Workflow: abc-enhancer-gene-prediction

Fetched 2025-05-03 03:56:21 GMT

## Activity by Contact Model of Enhancer-Gene Specificity in Common Workflow Language [broadinstitute/ABC-Enhancer-Gene-Prediction: Cell type specific enhancer-gene predictions using ABC model (Fulco, Nasser et al, Nature Genetics 2019)](https://github.com/broadinstitute/ABC-Enhancer-Gene-Prediction)

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Inputs

ID Type Title Doc
bam File
dhs File

wgEncodeUwDnaseK562AlnRep1.chr22.bam

genes File
H3K27ac File

ENCFF384ZZM.chr22.bam

cell_type String
sort_order File
chrom_sizes File

example_chr22/reference/chr22

hi_c_directory Directory

example_chr22/input_data/HiC/raw/

hi_c_resolution Integer
expression_table File

K562.ENCFF934YBO.TPM.txt

regions_blocklist File
regions_includelist File
ubiquitously_expressed_genes File

UbiquitouslyExpressedGenesHG19.txt

Steps

ID Runs Label Doc
abc_step01 abc_step01

Outputs

ID Type Label Doc
abc_step01_outputs File[] ABC Step01 Outputs
run_neighborhood_output File[] Run Neighborhoods Output

Candidate enhancer regions with Dnase-seq and H3K27ac ChIP-seq read counts

outputs_compute_abc_score File[]
Permalink: https://w3id.org/cwl/view/git/6146d0867e60b9f72da3239fd800bfc5dc914700/abc_enhancer_gene_prediction/abc-enchancer-gene-prediction-wf.cwl