digraph workflow {
	graph [_draw_="c 9 -#fffffe00 C 7 -#eeeeee P 4 0 0 0 368 1209 368 1209 0 ",
		bb="0,0,1209,368",
		bgcolor="#eeeeee",
		clusterrank=local,
		color=black,
		dpi=96,
		fontsize=10,
		labeljust=left,
		nodesep=0.05,
		ranksep=0.22,
		xdotversion=1.7
	];
	node [color=black,
		fillcolor=lightgoldenrodyellow,
		fontcolor=black,
		fontname=Helvetica,
		fontsize=10,
		height=0,
		label="\N",
		shape=record,
		style=filled,
		width=0
	];
	edge [arrowsize=0.7,
		color=black,
		fontcolor=black,
		fontname=Helvetica,
		fontsize=8
	];
	subgraph cluster_inputs {
		graph [_draw_="S 6 -dashed c 7 -#000000 C 7 -#eeeeee P 4 8 305 8 360 1201 360 1201 305 ",
			_ldraw_="F 10 11 -Times-Roman c 7 -#000000 T 58 348 0 84 15 -Workflow Inputs ",
			bb="8,305,1201,360",
			label="Workflow Inputs",
			lheight=0.15,
			lp="58,350.5",
			lwidth=1.17,
			rank=same,
			style=dashed
		];
		max_alt_alleles_in_normal_count	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 550 313.5 550 332.5 730 332.5 730 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 640 320.5 0 164 31 -max_alt_alleles_in_normal_count ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=max_alt_alleles_in_normal_count,
			pos="640,323",
			rects="550,313.5,730,332.5",
			width=2.5];
		scatter_count	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 16.5 313.5 16.5 332.5 99.5 332.5 99.5 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 58 320.5 0 67 13 -scatter_count ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=scatter_count,
			pos="58,323",
			rects="16.5,313.5,99.5,332.5",
			width=1.1528];
		artifact_detection_mode	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 410 313.5 410 332.5 546 332.5 546 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 478 320.5 0 120 23 -artifact_detection_mode ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=artifact_detection_mode,
			pos="478,323",
			rects="410,313.5,546,332.5",
			width=1.8889];
		dbsnp_vcf	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 182 313.5 182 332.5 248 332.5 248 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 215 320.5 0 50 9 -dbsnp_vcf ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=dbsnp_vcf,
			pos="215,323",
			rects="182,313.5,248,332.5",
			width=0.91667];
		reference	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 923.5 313.5 923.5 332.5 986.5 332.5 986.5 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 955 320.5 0 47 9 -reference ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=reference,
			pos="955,323",
			rects="923.5,313.5,986.5,332.5",
			width=0.875];
		cosmic_vcf	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 252.5 313.5 252.5 332.5 323.5 332.5 323.5 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 288 320.5 0 55 10 -cosmic_vcf ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=cosmic_vcf,
			pos="288,323",
			rects="252.5,313.5,323.5,332.5",
			width=0.98611];
		normal_bam	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 328 313.5 328 332.5 406 332.5 406 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 367 320.5 0 62 10 -normal_bam ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=normal_bam,
			pos="367,323",
			rects="328,313.5,406,332.5",
			width=1.0833];
		max_alt_allele_in_normal_fraction	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 734.5 313.5 734.5 332.5 919.5 332.5 919.5 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 827 320.5 0 169 33 -max_alt_allele_in_normal_fraction ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=max_alt_allele_in_normal_fraction,
			pos="827,323",
			rects="734.5,313.5,919.5,332.5",
			width=2.5694];
		interval_list	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 104 313.5 104 332.5 178 332.5 178 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 141 320.5 0 58 13 -interval_list ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=interval_list,
			pos="141,323",
			rects="104,313.5,178,332.5",
			width=1.0278];
		tumor_bam	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 1119.5 313.5 1119.5 332.5 1192.5 332.5 1192.5 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1156 320.5 0 57 9 -tumor_bam ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=tumor_bam,
			pos="1156,323",
			rects="1119.5,313.5,1192.5,332.5",
			width=1.0139];
		panel_of_normals_vcf	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 991 313.5 991 332.5 1115 332.5 1115 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1053 320.5 0 108 20 -panel_of_normals_vcf ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=panel_of_normals_vcf,
			pos="1053,323",
			rects="991,313.5,1115,332.5",
			width=1.7222];
	}
	subgraph cluster_outputs {
		graph [_draw_="S 6 -dashed c 7 -#000000 C 7 -#eeeeee P 4 907 8 907 63 1082 63 1082 8 ",
			_ldraw_="F 10 11 -Times-Roman c 7 -#000000 T 961 15 0 92 16 -Workflow Outputs ",
			bb="907,8,1082,63",
			label="Workflow Outputs",
			labelloc=b,
			lheight=0.15,
			lp="961,17.5",
			lwidth=1.28,
			rank=same,
			style=dashed
		];
		unfiltered_vcf	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 915.5 35.5 915.5 54.5 998.5 54.5 998.5 35.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 957 42.5 0 67 14 -unfiltered_vcf ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=unfiltered_vcf,
			pos="957,45",
			rects="915.5,35.5,998.5,54.5",
			width=1.1528];
		filtered_vcf	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 1002.5 35.5 1002.5 54.5 1073.5 54.5 1073.5 35.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1038 42.5 0 55 12 -filtered_vcf ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=filtered_vcf,
			pos="1038,45",
			rects="1002.5,35.5,1073.5,54.5",
			width=0.98611];
	}
	mutect	[_draw_="c 7 -#000000 C 7 -#fafad2 P 4 575 215.5 575 234.5 687 234.5 687 215.5 ",
		_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 631 222.5 0 96 18 -mutect2 (GATK 3.6) ",
		height=0.27778,
		label="mutect2 (GATK 3.6)",
		pos="631,225",
		rects="575,215.5,687,234.5",
		width=1.5556];
	max_alt_alleles_in_normal_count -> mutect	[_draw_="c 7 -#000000 B 7 638.59 313.66 637.21 305.2 635.16 291.73 634 280 632.77 267.57 632.01 253.48 631.56 242.8 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 634.01 242.85 631.3 235.95 629.12 243.04 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 700.5 268.1 0 133 31 -max_alt_alleles_in_normal_count ",
		label=max_alt_alleles_in_normal_count,
		lp="700.5,270",
		pos="e,631.24,234.44 638.59,313.66 637.21,305.2 635.16,291.73 634,280 632.77,267.57 632.01,253.48 631.56,242.8"];
	split_interval_list	[_draw_="c 7 -#000000 C 7 -#fafad2 P 4 90.5 260.5 90.5 279.5 191.5 279.5 191.5 260.5 ",
		_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 141 267.5 0 85 19 -split_interval_list ",
		height=0.27778,
		label=split_interval_list,
		pos="141,270",
		rects="90.5,260.5,191.5,279.5",
		width=1.4028];
	scatter_count -> split_interval_list	[_draw_="c 7 -#000000 B 7 62.43 313.5 66.89 305.77 74.46 294.58 84 288 86.87 286.02 89.97 284.27 93.2 282.72 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 94.02 285.03 99.5 280.04 92.1 280.52 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 112 290.6 0 56 13 -scatter_count ",
		label=scatter_count,
		lp="112,292.5",
		pos="e,100.89,279.45 62.435,313.5 66.891,305.77 74.458,294.58 84,288 86.869,286.02 89.972,284.27 93.198,282.72"];
	artifact_detection_mode -> mutect	[_draw_="c 7 -#000000 B 7 483.1 313.51 491.49 300.25 509.43 274.62 531 260 546.53 249.47 565.63 241.93 582.95 236.67 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 583.27 239.12 589.31 234.83 581.91 234.42 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 581 268.1 0 100 23 -artifact_detection_mode ",
		label=artifact_detection_mode,
		lp="581,270",
		pos="e,590.77,234.41 483.1,313.51 491.49,300.25 509.43,274.62 531,260 546.53,249.47 565.63,241.93 582.95,236.67"];
	dbsnp_vcf -> mutect	[_draw_="c 7 -#000000 B 7 222.95 313.55 236.38 299.85 265.02 273.03 295 260 342.31 239.44 483.32 231.08 566.87 227.86 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 566.86 230.32 573.76 227.61 566.67 225.42 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 316 268.1 0 42 9 -dbsnp_vcf ",
		label=dbsnp_vcf,
		lp="316,270",
		pos="e,575.27,227.55 222.95,313.55 236.38,299.85 265.02,273.03 295,260 342.31,239.44 483.32,231.08 566.87,227.86"];
	filter	[_draw_="c 7 -#000000 C 7 -#f3cea1 P 4 946.5 80.5 946.5 99.5 1047.5 99.5 1047.5 80.5 ",
		_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 997 87.5 0 85 18 -fp_filter workflow ",
		fillcolor="#F3CEA1",
		height=0.27778,
		label="fp_filter workflow",
		pos="997,90",
		rects="946.5,80.5,1047.5,99.5",
		width=1.4028];
	reference -> filter	[_draw_="c 7 -#000000 B 13 956.08 313.61 957.89 301.34 962.25 277.99 971 260 979.32 242.89 997 245.02 997 226 997 226 997 226 997 134 997 \
125.31 997 115.63 997 107.65 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 999.45 107.76 997 100.76 994.55 107.76 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1017 200.6 0 40 9 -reference ",
		label=reference,
		lp="1017,202.5",
		pos="e,997,99.243 956.08,313.61 957.89,301.34 962.25,277.99 971,260 979.32,242.89 997,245.02 997,226 997,226 997,226 997,134 997,125.31 \
997,115.63 997,107.65"];
	reference -> mutect	[_draw_="c 7 -#000000 B 10 947.26 313.69 939.8 305.48 928.45 292.39 920 280 914.28 271.62 917.4 265.68 909 260 875.24 237.16 766.43 229.65 \
695.37 227.19 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 695.49 224.74 688.42 226.96 695.33 229.64 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 940 268.1 0 40 9 -reference ",
		label=reference,
		lp="940,270",
		pos="e,686.9,226.92 947.26,313.69 939.8,305.48 928.45,292.39 920,280 914.28,271.62 917.4,265.68 909,260 875.24,237.16 766.43,229.65 695.37,\
227.19"];
	cosmic_vcf -> mutect	[_draw_="c 7 -#000000 B 7 296.56 313.57 310.99 299.9 341.66 273.11 373 260 406.98 245.79 502.31 235.89 567.07 230.57 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 566.92 233.04 573.7 230.04 566.53 228.16 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 395.5 268.1 0 45 10 -cosmic_vcf ",
		label=cosmic_vcf,
		lp="395.5,270",
		pos="e,575.21,229.92 296.56,313.57 310.99,299.9 341.66,273.11 373,260 406.98,245.79 502.31,235.89 567.07,230.57"];
	normal_bam -> mutect	[_draw_="c 7 -#000000 B 7 376.09 313.69 391.38 300.2 423.75 273.66 456 260 491.22 245.08 533.22 236.64 567.25 231.9 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 567.16 234.39 573.77 231.03 566.51 229.53 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 481.5 268.1 0 51 10 -normal_bam ",
		label=normal_bam,
		lp="481.5,270",
		pos="e,575.27,230.83 376.09,313.69 391.38,300.2 423.75,273.66 456,260 491.22,245.08 533.22,236.64 567.25,231.9"];
	max_alt_allele_in_normal_fraction -> mutect	[_draw_="c 7 -#000000 B 10 813.83 313.53 802.53 305.79 786.32 293.52 775 280 768.49 272.22 772.02 266.21 764 260 744.37 244.79 718.68 236.33 \
695.12 231.64 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 695.7 229.26 688.37 230.41 694.82 234.08 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 843.5 268.1 0 137 33 -max_alt_allele_in_normal_fraction ",
		label=max_alt_allele_in_normal_fraction,
		lp="843.5,270",
		pos="e,686.88,230.14 813.83,313.53 802.53,305.79 786.32,293.52 775,280 768.49,272.22 772.02,266.21 764,260 744.37,244.79 718.68,236.33 \
695.12,231.64"];
	interval_list -> split_interval_list	[_draw_="c 7 -#000000 B 4 141 313.58 141 306.52 141 296.24 141 287.55 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 143.45 287.78 141 280.78 138.55 287.78 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 164.5 290.6 0 47 13 -interval_list ",
		label=interval_list,
		lp="164.5,292.5",
		pos="e,141,279.26 141,313.58 141,306.52 141,296.24 141,287.55"];
	tumor_bam -> filter	[_draw_="c 7 -#000000 B 10 1152.85 313.84 1149.29 303.88 1144 286.46 1144 271 1144 271 1144 271 1144 134 1144 114.66 1096.53 103.41 1055.54 \
97.31 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1055.95 94.89 1048.68 96.33 1055.26 99.74 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1153.5 200.6 0 19 3 -bam ",
		label=bam,
		lp="1153.5,202.5",
		pos="e,1047.2,96.119 1152.8,313.84 1149.3,303.88 1144,286.46 1144,271 1144,271 1144,271 1144,134 1144,114.66 1096.5,103.41 1055.5,97.309"];
	tumor_bam -> mutect	[_draw_="c 7 -#000000 B 7 1143.44 313.52 1118.56 296.73 1065.23 260.83 1063 260 997.45 235.51 799.06 228.66 695.5 226.74 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 695.55 224.29 688.51 226.62 695.46 229.19 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1115 268.1 0 46 9 -tumor_bam ",
		label=tumor_bam,
		lp="1115,270",
		pos="e,687,226.59 1143.4,313.52 1118.6,296.73 1065.2,260.83 1063,260 997.45,235.51 799.06,228.66 695.5,226.74"];
	panel_of_normals_vcf -> mutect	[_draw_="c 7 -#000000 B 10 1033.65 313.53 1017.76 306.04 995.17 294.13 978 280 968.99 272.59 971.03 265.95 961 260 917.48 234.19 778.23 227.79 \
695.17 226.32 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 695.37 223.87 688.33 226.21 695.29 228.77 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1022 268.1 0 88 20 -panel_of_normals_vcf ",
		label=panel_of_normals_vcf,
		lp="1022,270",
		pos="e,686.82,226.18 1033.6,313.53 1017.8,306.04 995.17,294.13 978,280 968.99,272.59 971.03,265.95 961,260 917.48,234.19 778.23,227.79 \
695.17,226.32"];
	merge	[_draw_="c 7 -#000000 C 7 -#fafad2 P 4 843 170.5 843 189.5 909 189.5 909 170.5 ",
		_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 876 177.5 0 50 9 -vcf merge ",
		height=0.27778,
		label="vcf merge",
		pos="876,180",
		rects="843,170.5,909,189.5",
		width=0.91667];
	index	[_draw_="c 7 -#000000 C 7 -#fafad2 P 4 928 125.5 928 144.5 990 144.5 990 125.5 ",
		_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 959 132.5 0 46 9 -vcf index ",
		height=0.27778,
		label="vcf index",
		pos="959,135",
		rects="928,125.5,990,144.5",
		width=0.86111];
	merge -> index	[_draw_="c 7 -#000000 B 4 892.4 170.5 904.68 164.14 921.65 155.35 935.39 148.23 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 936.2 150.57 941.29 145.17 933.95 146.22 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 930.5 155.6 0 13 3 -vcf ",
		label=vcf,
		lp="930.5,157.5",
		pos="e,942.64,144.48 892.4,170.5 904.68,164.14 921.65,155.35 935.39,148.23"];
	filter -> unfiltered_vcf	[_draw_="c 7 -#000000 B 4 989.29 80.71 983.86 74.88 976.47 66.93 970.13 60.12 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 972.28 58.83 965.72 55.37 968.69 62.17 ",
		pos="e,964.69,54.265 989.29,80.709 983.86,74.879 976.47,66.934 970.13,60.117"];
	filter -> filtered_vcf	[_draw_="c 7 -#000000 B 4 1004.91 80.71 1010.46 74.88 1018.04 66.93 1024.54 60.12 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1026.02 62.12 1029.07 55.36 1022.47 58.74 ",
		pos="e,1030.1,54.265 1004.9,80.709 1010.5,74.879 1018,66.934 1024.5,60.117"];
	mutect -> merge	[_draw_="c 7 -#000000 B 4 679.4 215.5 724.9 207.52 792.24 195.7 835.11 188.18 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 835.39 190.62 841.86 186.99 834.54 185.79 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 783.5 200.6 0 17 4 -vcfs ",
		label=vcfs,
		lp="783.5,202.5",
		pos="e,843.35,186.73 679.4,215.5 724.9,207.52 792.24,195.7 835.11,188.18"];
	split_interval_list -> mutect	[_draw_="c 7 -#000000 B 7 162.19 260.57 178.52 254.49 201.82 246.73 223 243 287.11 231.71 469.21 227.87 567.01 226.6 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 566.86 229.05 573.83 226.51 566.8 224.15 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 246.5 245.6 0 47 13 -interval_list ",
		label=interval_list,
		lp="246.5,247.5",
		pos="e,575.35,226.5 162.19,260.57 178.52,254.49 201.82,246.73 223,243 287.11,231.71 469.21,227.87 567.01,226.6"];
	index -> filter	[_draw_="c 7 -#000000 B 7 965.4 125.62 969.46 120.43 974.88 113.7 980 108 980.72 107.2 981.47 106.38 982.24 105.57 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 983.98 107.28 987.11 100.56 980.47 103.87 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 986.5 110.6 0 13 3 -vcf ",
		label=vcf,
		lp="986.5,112.5",
		pos="e,988.17,99.476 965.4,125.62 969.46,120.43 974.88,113.7 980,108 980.72,107.2 981.47,106.38 982.24,105.57"];
}
