digraph workflow {
	graph [_draw_="c 9 -#fffffe00 C 7 -#eeeeee P 4 0 0 0 368 1213 368 1213 0 ",
		bb="0,0,1213,368",
		bgcolor="#eeeeee",
		clusterrank=local,
		color=black,
		dpi=96,
		fontsize=10,
		labeljust=left,
		nodesep=0.05,
		ranksep=0.22,
		xdotversion=1.7
	];
	node [color=black,
		fillcolor=lightgoldenrodyellow,
		fontcolor=black,
		fontname=Helvetica,
		fontsize=10,
		height=0,
		label="\N",
		shape=record,
		style=filled,
		width=0
	];
	edge [arrowsize=0.7,
		color=black,
		fontcolor=black,
		fontname=Helvetica,
		fontsize=8
	];
	subgraph cluster_inputs {
		graph [_draw_="S 6 -dashed c 7 -#000000 C 7 -#eeeeee P 4 8 305 8 360 1205 360 1205 305 ",
			_ldraw_="F 10 11 -Times-Roman c 7 -#000000 T 58 348 0 84 15 -Workflow Inputs ",
			bb="8,305,1205,360",
			label="Workflow Inputs",
			lheight=0.15,
			lp="58,350.5",
			lwidth=1.17,
			rank=same,
			style=dashed
		];
		cosmic_vcf	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 503.5 313.5 503.5 332.5 574.5 332.5 574.5 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 539 320.5 0 55 10 -cosmic_vcf ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=cosmic_vcf,
			pos="539,323",
			rects="503.5,313.5,574.5,332.5",
			width=0.98611];
		panel_of_normals_vcf	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 853 313.5 853 332.5 977 332.5 977 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 915 320.5 0 108 20 -panel_of_normals_vcf ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=panel_of_normals_vcf,
			pos="915,323",
			rects="853,313.5,977,332.5",
			width=1.7222];
		artifact_detection_mode	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 1061 313.5 1061 332.5 1197 332.5 1197 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1129 320.5 0 120 23 -artifact_detection_mode ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=artifact_detection_mode,
			pos="1129,323",
			rects="1061,313.5,1197,332.5",
			width=1.8889];
		reference	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 103.5 313.5 103.5 332.5 166.5 332.5 166.5 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 135 320.5 0 47 9 -reference ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=reference,
			pos="135,323",
			rects="103.5,313.5,166.5,332.5",
			width=0.875];
		scatter_count	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 16.5 313.5 16.5 332.5 99.5 332.5 99.5 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 58 320.5 0 67 13 -scatter_count ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=scatter_count,
			pos="58,323",
			rects="16.5,313.5,99.5,332.5",
			width=1.1528];
		max_alt_alleles_in_normal_count	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 249 313.5 249 332.5 429 332.5 429 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 339 320.5 0 164 31 -max_alt_alleles_in_normal_count ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=max_alt_alleles_in_normal_count,
			pos="339,323",
			rects="249,313.5,429,332.5",
			width=2.5];
		dbsnp_vcf	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 433 313.5 433 332.5 499 332.5 499 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 466 320.5 0 50 9 -dbsnp_vcf ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=dbsnp_vcf,
			pos="466,323",
			rects="433,313.5,499,332.5",
			width=0.91667];
		tumor_cram	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 981 313.5 981 332.5 1057 332.5 1057 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1019 320.5 0 60 10 -tumor_cram ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=tumor_cram,
			pos="1019,323",
			rects="981,313.5,1057,332.5",
			width=1.0556];
		interval_list	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 171 313.5 171 332.5 245 332.5 245 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 208 320.5 0 58 13 -interval_list ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=interval_list,
			pos="208,323",
			rects="171,313.5,245,332.5",
			width=1.0278];
		normal_cram	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 578.5 313.5 578.5 332.5 659.5 332.5 659.5 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 619 320.5 0 65 11 -normal_cram ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=normal_cram,
			pos="619,323",
			rects="578.5,313.5,659.5,332.5",
			width=1.125];
		max_alt_allele_in_normal_fraction	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 663.5 313.5 663.5 332.5 848.5 332.5 848.5 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 756 320.5 0 169 33 -max_alt_allele_in_normal_fraction ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=max_alt_allele_in_normal_fraction,
			pos="756,323",
			rects="663.5,313.5,848.5,332.5",
			width=2.5694];
	}
	subgraph cluster_outputs {
		graph [_draw_="S 6 -dashed c 7 -#000000 C 7 -#eeeeee P 4 473 8 473 63 648 63 648 8 ",
			_ldraw_="F 10 11 -Times-Roman c 7 -#000000 T 527 15 0 92 16 -Workflow Outputs ",
			bb="473,8,648,63",
			label="Workflow Outputs",
			labelloc=b,
			lheight=0.15,
			lp="527,17.5",
			lwidth=1.28,
			rank=same,
			style=dashed
		];
		unfiltered_vcf	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 481.5 35.5 481.5 54.5 564.5 54.5 564.5 35.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 523 42.5 0 67 14 -unfiltered_vcf ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=unfiltered_vcf,
			pos="523,45",
			rects="481.5,35.5,564.5,54.5",
			width=1.1528];
		filtered_vcf	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 568.5 35.5 568.5 54.5 639.5 54.5 639.5 35.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 604 42.5 0 55 12 -filtered_vcf ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=filtered_vcf,
			pos="604,45",
			rects="568.5,35.5,639.5,54.5",
			width=0.98611];
	}
	mutect	[_draw_="c 7 -#000000 C 7 -#fafad2 P 4 507 215.5 507 234.5 619 234.5 619 215.5 ",
		_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 563 222.5 0 96 18 -mutect2 (GATK 3.6) ",
		height=0.27778,
		label="mutect2 (GATK 3.6)",
		pos="563,225",
		rects="507,215.5,619,234.5",
		width=1.5556];
	cosmic_vcf -> mutect	[_draw_="c 7 -#000000 B 7 537.67 313.74 536.05 301.62 534.17 278.48 540 260 542.14 253.21 546.11 246.55 550.16 240.94 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 551.89 242.7 554.26 235.67 548.03 239.69 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 562.5 268.1 0 45 10 -cosmic_vcf ",
		label=cosmic_vcf,
		lp="562.5,270",
		pos="e,555.19,234.48 537.67,313.74 536.05,301.62 534.17,278.48 540,260 542.14,253.21 546.11,246.55 550.16,240.94"];
	panel_of_normals_vcf -> mutect	[_draw_="c 7 -#000000 B 10 884.35 313.57 854.6 304.93 812.1 291.21 799 280 791.29 273.41 796.32 265.8 788 260 762.67 242.34 684.39 233.57 \
627.26 229.42 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 627.66 226.99 620.51 228.94 627.32 231.88 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 843 268.1 0 88 20 -panel_of_normals_vcf ",
		label=panel_of_normals_vcf,
		lp="843,270",
		pos="e,619,228.84 884.35,313.57 854.6,304.93 812.1,291.21 799,280 791.29,273.41 796.32,265.8 788,260 762.67,242.34 684.39,233.57 627.26,\
229.42"];
	artifact_detection_mode -> mutect	[_draw_="c 7 -#000000 B 7 1106.4 313.58 1071.36 300.74 1001.63 276.07 941 260 833.31 231.45 702.97 225.78 626.88 225.22 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 627.31 222.78 620.3 225.19 627.29 227.68 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1057 268.1 0 100 23 -artifact_detection_mode ",
		label=artifact_detection_mode,
		lp="1057,270",
		pos="e,618.79,225.18 1106.4,313.58 1071.4,300.74 1001.6,276.07 941,260 833.31,231.45 702.97,225.78 626.88,225.22"];
	filter	[_draw_="c 7 -#000000 C 7 -#f3cea1 P 4 512.5 80.5 512.5 99.5 613.5 99.5 613.5 80.5 ",
		_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 563 87.5 0 85 18 -fp_filter workflow ",
		fillcolor="#F3CEA1",
		height=0.27778,
		label="fp_filter workflow",
		pos="563,90",
		rects="512.5,80.5,613.5,99.5",
		width=1.4028];
	reference -> filter	[_draw_="c 7 -#000000 B 10 135 313.7 135 303.6 135 286.05 135 271 135 271 135 271 135 134 135 97.31 387.25 91.61 504.45 90.94 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 504.14 93.39 511.13 90.91 504.12 88.49 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 155 200.6 0 40 9 -reference ",
		label=reference,
		lp="155,202.5",
		pos="e,512.64,90.903 135,313.7 135,303.6 135,286.05 135,271 135,271 135,271 135,134 135,97.307 387.25,91.61 504.45,90.943"];
	reference -> mutect	[_draw_="c 7 -#000000 B 16 151.68 313.65 157.7 310.76 164.6 307.6 171 305 202.78 292.1 211.85 291.93 244 280 266.44 271.68 271.31 267.62 \
294 260 321.09 250.9 327.86 247.97 356 243 403.51 234.61 457.89 230.35 498.99 228.19 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 498.91 230.65 505.78 227.85 498.67 225.75 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 314 268.1 0 40 9 -reference ",
		label=reference,
		lp="314,270",
		pos="e,507.29,227.77 151.68,313.65 157.7,310.76 164.6,307.6 171,305 202.78,292.1 211.85,291.93 244,280 266.44,271.68 271.31,267.62 294,\
260 321.09,250.9 327.86,247.97 356,243 403.51,234.61 457.89,230.35 498.99,228.19"];
	split_interval_list	[_draw_="c 7 -#000000 C 7 -#fafad2 P 4 142.5 260.5 142.5 279.5 243.5 279.5 243.5 260.5 ",
		_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 193 267.5 0 85 19 -split_interval_list ",
		height=0.27778,
		label=split_interval_list,
		pos="193,270",
		rects="142.5,260.5,243.5,279.5",
		width=1.4028];
	scatter_count -> split_interval_list	[_draw_="c 7 -#000000 B 4 80.29 313.58 102.86 305.05 137.91 291.81 162.93 282.36 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 163.58 284.73 169.26 279.97 161.84 280.15 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 173 290.6 0 56 13 -scatter_count ",
		label=scatter_count,
		lp="173,292.5",
		pos="e,170.67,279.43 80.293,313.58 102.86,305.05 137.91,291.81 162.93,282.36"];
	max_alt_alleles_in_normal_count -> mutect	[_draw_="c 7 -#000000 B 7 337 313.91 334.28 300.73 331.2 274.63 345 260 365.54 238.22 442.28 230.36 498.92 227.55 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 498.73 230.01 505.61 227.24 498.51 225.11 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 411.5 268.1 0 133 31 -max_alt_alleles_in_normal_count ",
		label=max_alt_alleles_in_normal_count,
		lp="411.5,270",
		pos="e,507.12,227.16 337,313.91 334.28,300.73 331.2,274.63 345,260 365.54,238.22 442.28,230.36 498.92,227.55"];
	dbsnp_vcf -> mutect	[_draw_="c 7 -#000000 B 7 467.66 313.74 470.64 300.8 478.04 275.59 493 260 502.36 250.24 515.1 242.92 527.15 237.62 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 527.98 239.92 533.52 234.99 526.11 235.39 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 514 268.1 0 42 9 -dbsnp_vcf ",
		label=dbsnp_vcf,
		lp="514,270",
		pos="e,534.92,234.42 467.66,313.74 470.64,300.8 478.04,275.59 493,260 502.36,250.24 515.1,242.92 527.15,237.62"];
	tumor_cram -> filter	[_draw_="c 7 -#000000 B 13 1026.55 313.62 1033.41 305.57 1043.31 292.77 1049 280 1054.84 266.9 1056 262.84 1056 248.5 1056 248.5 1056 248.5 \
1056 134 1056 112.43 752.56 98.24 621.8 93.12 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 622.04 90.68 614.96 92.86 621.86 95.58 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1066.5 200.6 0 21 4 -cram ",
		label=cram,
		lp="1066.5,202.5",
		pos="e,613.44,92.801 1026.6,313.62 1033.4,305.57 1043.3,292.77 1049,280 1054.8,266.9 1056,262.84 1056,248.5 1056,248.5 1056,248.5 1056,\
134 1056,112.43 752.56,98.239 621.8,93.125"];
	tumor_cram -> mutect	[_draw_="c 7 -#000000 B 13 999.06 313.51 992.13 310.67 984.27 307.57 977 305 941.08 292.28 924.58 304.01 895 280 887.12 273.61 892.37 265.74 \
884 260 843.56 232.27 708.42 226.56 626.94 225.73 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 627.27 223.28 620.25 225.67 627.23 228.18 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 919.5 268.1 0 49 10 -tumor_cram ",
		label=tumor_cram,
		lp="919.5,270",
		pos="e,618.74,225.66 999.06,313.51 992.13,310.67 984.27,307.57 977,305 941.08,292.28 924.58,304.01 895,280 887.12,273.61 892.37,265.74 \
884,260 843.56,232.27 708.42,226.56 626.94,225.73"];
	interval_list -> split_interval_list	[_draw_="c 7 -#000000 B 4 205.52 313.58 203.43 306.45 200.36 296.02 197.79 287.27 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 200.18 286.74 195.86 280.72 195.48 288.12 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 223.5 290.6 0 47 13 -interval_list ",
		label=interval_list,
		lp="223.5,292.5",
		pos="e,195.43,279.26 205.52,313.58 203.43,306.45 200.36,296.02 197.79,287.27"];
	normal_cram -> mutect	[_draw_="c 7 -#000000 B 10 613.69 313.71 608.35 305.29 599.92 291.85 593 280 587.88 271.24 586.92 268.87 582 260 578.66 253.98 574.98 247.38 \
571.75 241.6 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 574 240.61 568.44 235.7 569.72 243 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 619.5 268.1 0 53 11 -normal_cram ",
		label=normal_cram,
		lp="619.5,270",
		pos="e,567.7,234.37 613.69,313.71 608.35,305.29 599.92,291.85 593,280 587.88,271.24 586.92,268.87 582,260 578.66,253.98 574.98,247.38 \
571.75,241.6"];
	max_alt_allele_in_normal_fraction -> mutect	[_draw_="c 7 -#000000 B 10 719.69 313.55 698.58 307.16 672.56 296.59 654 280 646.44 273.24 650.53 266.8 643 260 631.86 249.93 617.3 242.56 \
603.66 237.3 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 604.6 235.04 597.19 234.96 602.94 239.64 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 722.5 268.1 0 137 33 -max_alt_allele_in_normal_fraction ",
		label=max_alt_allele_in_normal_fraction,
		lp="722.5,270",
		pos="e,595.76,234.44 719.69,313.55 698.58,307.16 672.56,296.59 654,280 646.44,273.24 650.53,266.8 643,260 631.86,249.93 617.3,242.56 \
603.66,237.3"];
	filter -> unfiltered_vcf	[_draw_="c 7 -#000000 B 4 555.29 80.71 549.86 74.88 542.47 66.93 536.13 60.12 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 538.28 58.83 531.72 55.37 534.69 62.17 ",
		pos="e,530.69,54.265 555.29,80.709 549.86,74.879 542.47,66.934 536.13,60.117"];
	filter -> filtered_vcf	[_draw_="c 7 -#000000 B 4 570.91 80.71 576.46 74.88 584.04 66.93 590.54 60.12 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 592.02 62.12 595.07 55.36 588.47 58.74 ",
		pos="e,596.12,54.265 570.91,80.709 576.46,74.879 584.04,66.934 590.54,60.117"];
	split_interval_list -> mutect	[_draw_="c 7 -#000000 B 7 193.19 260.57 193.82 254.66 195.7 247.11 201 243 212.55 234.05 397.97 229.14 498.83 227.11 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 498.67 229.57 505.62 226.98 498.57 224.67 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 224.5 245.6 0 47 13 -interval_list ",
		label=interval_list,
		lp="224.5,247.5",
		pos="e,507.13,226.95 193.19,260.57 193.82,254.66 195.7,247.11 201,243 212.55,234.05 397.97,229.14 498.83,227.11"];
	merge	[_draw_="c 7 -#000000 C 7 -#fafad2 P 4 530 170.5 530 189.5 596 189.5 596 170.5 ",
		_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 563 177.5 0 50 9 -vcf merge ",
		height=0.27778,
		label="vcf merge",
		pos="563,180",
		rects="530,170.5,596,189.5",
		width=0.91667];
	mutect -> merge	[_draw_="c 7 -#000000 B 4 563 215.71 563 210.59 563 203.85 563 197.67 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 565.45 197.78 563 190.78 560.55 197.78 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 571.5 200.6 0 17 4 -vcfs ",
		label=vcfs,
		lp="571.5,202.5",
		pos="e,563,189.27 563,215.71 563,210.59 563,203.85 563,197.67"];
	index	[_draw_="c 7 -#000000 C 7 -#fafad2 P 4 532 125.5 532 144.5 594 144.5 594 125.5 ",
		_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 563 132.5 0 46 9 -vcf index ",
		height=0.27778,
		label="vcf index",
		pos="563,135",
		rects="532,125.5,594,144.5",
		width=0.86111];
	merge -> index	[_draw_="c 7 -#000000 B 4 563 170.71 563 165.59 563 158.85 563 152.67 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 565.45 152.78 563 145.78 560.55 152.78 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 569.5 155.6 0 13 3 -vcf ",
		label=vcf,
		lp="569.5,157.5",
		pos="e,563,144.27 563,170.71 563,165.59 563,158.85 563,152.67"];
	index -> filter	[_draw_="c 7 -#000000 B 4 563 125.71 563 120.59 563 113.85 563 107.67 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 565.45 107.78 563 100.78 560.55 107.78 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 569.5 110.6 0 13 3 -vcf ",
		label=vcf,
		lp="569.5,112.5",
		pos="e,563,99.265 563,125.71 563,120.59 563,113.85 563,107.67"];
}