digraph workflow {
	graph [_draw_="c 9 -#fffffe00 C 7 -#eeeeee P 4 0 0 0 368 1209 368 1209 0 ",
		bb="0,0,1209,368",
		bgcolor="#eeeeee",
		clusterrank=local,
		color=black,
		dpi=96,
		fontsize=10,
		labeljust=left,
		nodesep=0.05,
		ranksep=0.22,
		xdotversion=1.7
	];
	node [color=black,
		fillcolor=lightgoldenrodyellow,
		fontcolor=black,
		fontname=Helvetica,
		fontsize=10,
		height=0,
		label="\N",
		shape=record,
		style=filled,
		width=0
	];
	edge [arrowsize=0.7,
		color=black,
		fontcolor=black,
		fontname=Helvetica,
		fontsize=8
	];
	subgraph cluster_inputs {
		graph [_draw_="S 6 -dashed c 7 -#000000 C 7 -#eeeeee P 4 8 305 8 360 1201 360 1201 305 ",
			_ldraw_="F 10 11 -Times-Roman c 7 -#000000 T 58 348 0 84 15 -Workflow Inputs ",
			bb="8,305,1201,360",
			label="Workflow Inputs",
			lheight=0.15,
			lp="58,350.5",
			lwidth=1.17,
			rank=same,
			style=dashed
		];
		cosmic_vcf	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 471.5 313.5 471.5 332.5 542.5 332.5 542.5 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 507 320.5 0 55 10 -cosmic_vcf ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=cosmic_vcf,
			pos="507,323",
			rects="471.5,313.5,542.5,332.5",
			width=0.98611];
		dbsnp_vcf	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 547 313.5 547 332.5 613 332.5 613 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 580 320.5 0 50 9 -dbsnp_vcf ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=dbsnp_vcf,
			pos="580,323",
			rects="547,313.5,613,332.5",
			width=0.91667];
		reference	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 16.5 313.5 16.5 332.5 79.5 332.5 79.5 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 48 320.5 0 47 9 -reference ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=reference,
			pos="48,323",
			rects="16.5,313.5,79.5,332.5",
			width=0.875];
		max_alt_allele_in_normal_fraction	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 801.5 313.5 801.5 332.5 986.5 332.5 986.5 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 894 320.5 0 169 33 -max_alt_allele_in_normal_fraction ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=max_alt_allele_in_normal_fraction,
			pos="894,323",
			rects="801.5,313.5,986.5,332.5",
			width=2.5694];
		max_alt_alleles_in_normal_count	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 617 313.5 617 332.5 797 332.5 797 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 707 320.5 0 164 31 -max_alt_alleles_in_normal_count ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=max_alt_alleles_in_normal_count,
			pos="707,323",
			rects="617,313.5,797,332.5",
			width=2.5];
		panel_of_normals_vcf	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 991 313.5 991 332.5 1115 332.5 1115 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1053 320.5 0 108 20 -panel_of_normals_vcf ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=panel_of_normals_vcf,
			pos="1053,323",
			rects="991,313.5,1115,332.5",
			width=1.7222];
		normal_bam	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 84 313.5 84 332.5 162 332.5 162 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 123 320.5 0 62 10 -normal_bam ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=normal_bam,
			pos="123,323",
			rects="84,313.5,162,332.5",
			width=1.0833];
		artifact_detection_mode	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 166 313.5 166 332.5 302 332.5 302 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 234 320.5 0 120 23 -artifact_detection_mode ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=artifact_detection_mode,
			pos="234,323",
			rects="166,313.5,302,332.5",
			width=1.8889];
		scatter_count	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 384.5 313.5 384.5 332.5 467.5 332.5 467.5 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 426 320.5 0 67 13 -scatter_count ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=scatter_count,
			pos="426,323",
			rects="384.5,313.5,467.5,332.5",
			width=1.1528];
		tumor_bam	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 1119.5 313.5 1119.5 332.5 1192.5 332.5 1192.5 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1156 320.5 0 57 9 -tumor_bam ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=tumor_bam,
			pos="1156,323",
			rects="1119.5,313.5,1192.5,332.5",
			width=1.0139];
		interval_list	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 306 313.5 306 332.5 380 332.5 380 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 343 320.5 0 58 13 -interval_list ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=interval_list,
			pos="343,323",
			rects="306,313.5,380,332.5",
			width=1.0278];
	}
	subgraph cluster_outputs {
		graph [_draw_="S 6 -dashed c 7 -#000000 C 7 -#eeeeee P 4 456 8 456 63 631 63 631 8 ",
			_ldraw_="F 10 11 -Times-Roman c 7 -#000000 T 510 15 0 92 16 -Workflow Outputs ",
			bb="456,8,631,63",
			label="Workflow Outputs",
			labelloc=b,
			lheight=0.15,
			lp="510,17.5",
			lwidth=1.28,
			rank=same,
			style=dashed
		];
		filtered_vcf	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 464.5 35.5 464.5 54.5 535.5 54.5 535.5 35.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 500 42.5 0 55 12 -filtered_vcf ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=filtered_vcf,
			pos="500,45",
			rects="464.5,35.5,535.5,54.5",
			width=0.98611];
		unfiltered_vcf	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 539.5 35.5 539.5 54.5 622.5 54.5 622.5 35.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 581 42.5 0 67 14 -unfiltered_vcf ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=unfiltered_vcf,
			pos="581,45",
			rects="539.5,35.5,622.5,54.5",
			width=1.1528];
	}
	mutect	[_draw_="c 7 -#000000 C 7 -#fafad2 P 4 484 215.5 484 234.5 596 234.5 596 215.5 ",
		_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 540 222.5 0 96 18 -mutect2 (GATK 3.6) ",
		height=0.27778,
		label="mutect2 (GATK 3.6)",
		pos="540,225",
		rects="484,215.5,596,234.5",
		width=1.5556];
	cosmic_vcf -> mutect	[_draw_="c 7 -#000000 B 7 508.31 313.78 510.39 301.72 514.94 278.64 522 260 524.38 253.73 527.65 247.15 530.76 241.47 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 532.71 243 534.05 235.7 528.46 240.57 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 544.5 268.1 0 45 10 -cosmic_vcf ",
		label=cosmic_vcf,
		lp="544.5,270",
		pos="e,534.8,234.39 508.31,313.78 510.39,301.72 514.94,278.64 522,260 524.38,253.73 527.65,247.15 530.76,241.47"];
	dbsnp_vcf -> mutect	[_draw_="c 7 -#000000 B 7 578.83 313.65 576.9 301.43 572.41 278.16 564 260 560.93 253.36 556.53 246.66 552.34 240.97 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 554.4 239.64 548.18 235.6 550.53 242.64 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 592 268.1 0 42 9 -dbsnp_vcf ",
		label=dbsnp_vcf,
		lp="592,270",
		pos="e,547.25,234.41 578.83,313.65 576.9,301.43 572.41,278.16 564,260 560.93,253.36 556.53,246.66 552.34,240.97"];
	reference -> mutect	[_draw_="c 7 -#000000 B 7 55.96 313.58 69.41 299.93 98.09 273.17 128 260 188.56 233.34 375.6 227.45 475.52 226.23 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 475.54 228.68 482.51 226.16 475.49 223.79 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 148 268.1 0 40 9 -reference ",
		label=reference,
		lp="148,270",
		pos="e,484.03,226.14 55.964,313.58 69.41,299.93 98.087,273.17 128,260 188.56,233.34 375.6,227.45 475.52,226.23"];
	filter	[_draw_="c 7 -#000000 C 7 -#f3cea1 P 4 489.5 80.5 489.5 99.5 590.5 99.5 590.5 80.5 ",
		_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 540 87.5 0 85 18 -fp_filter workflow ",
		fillcolor="#F3CEA1",
		height=0.27778,
		label="fp_filter workflow",
		pos="540,90",
		rects="489.5,80.5,590.5,99.5",
		width=1.4028];
	reference -> filter	[_draw_="c 7 -#000000 B 10 49.84 313.74 51.91 303.7 55 286.19 55 271 55 271 55 271 55 134 55 91.61 352.79 89.25 481.68 90.21 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 481.39 92.66 488.41 90.27 481.43 87.76 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 75 200.6 0 40 9 -reference ",
		label=reference,
		lp="75,202.5",
		pos="e,489.92,90.282 49.839,313.74 51.913,303.7 55,286.19 55,271 55,271 55,271 55,134 55,91.608 352.79,89.249 481.68,90.214"];
	max_alt_allele_in_normal_fraction -> mutect	[_draw_="c 7 -#000000 B 7 882.01 313.58 861.94 299.93 819.78 273.16 780 260 722.21 240.89 653.12 232.52 603.93 228.85 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 604.27 226.42 597.11 228.37 603.92 231.31 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 893.5 268.1 0 137 33 -max_alt_allele_in_normal_fraction ",
		label=max_alt_allele_in_normal_fraction,
		lp="893.5,270",
		pos="e,595.6,228.26 882.01,313.58 861.94,299.93 819.78,273.16 780,260 722.21,240.89 653.12,232.52 603.93,228.85"];
	max_alt_alleles_in_normal_count -> mutect	[_draw_="c 7 -#000000 B 7 695.63 313.56 678.46 301.03 644.66 277.13 614 260 599.21 251.74 582.06 243.76 567.99 237.62 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 569.31 235.52 561.92 235 567.37 240.02 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 712.5 268.1 0 133 31 -max_alt_alleles_in_normal_count ",
		label=max_alt_alleles_in_normal_count,
		lp="712.5,270",
		pos="e,560.53,234.4 695.63,313.56 678.46,301.03 644.66,277.13 614,260 599.21,251.74 582.06,243.76 567.99,237.62"];
	panel_of_normals_vcf -> mutect	[_draw_="c 7 -#000000 B 7 1044.44 313.73 1029.39 299.79 996.61 271.95 963 260 898.69 237.13 705.87 229.55 604.27 227.11 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 604.49 224.67 597.43 226.96 604.37 229.57 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1045 268.1 0 88 20 -panel_of_normals_vcf ",
		label=panel_of_normals_vcf,
		lp="1045,270",
		pos="e,595.92,226.92 1044.4,313.73 1029.4,299.79 996.61,271.95 963,260 898.69,237.13 705.87,229.55 604.27,227.11"];
	normal_bam -> mutect	[_draw_="c 7 -#000000 B 7 130.87 313.63 144.15 300.06 172.47 273.4 202 260 249.31 238.53 391.62 230.51 475.74 227.59 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 475.76 230.04 482.68 227.36 475.6 225.15 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 227.5 268.1 0 51 10 -normal_bam ",
		label=normal_bam,
		lp="227.5,270",
		pos="e,484.19,227.31 130.87,313.63 144.15,300.06 172.47,273.4 202,260 249.31,238.53 391.62,230.51 475.74,227.59"];
	artifact_detection_mode -> mutect	[_draw_="c 7 -#000000 B 7 236.66 313.92 241.61 300.26 253.63 272.84 274 260 306.53 239.49 407.83 231.3 475.61 228.06 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 475.72 230.51 482.6 227.74 475.49 225.61 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 324 268.1 0 100 23 -artifact_detection_mode ",
		label=artifact_detection_mode,
		lp="324,270",
		pos="e,484.11,227.67 236.66,313.92 241.61,300.26 253.63,272.84 274,260 306.53,239.49 407.83,231.3 475.61,228.06"];
	split_interval_list	[_draw_="c 7 -#000000 C 7 -#fafad2 P 4 375.5 260.5 375.5 279.5 476.5 279.5 476.5 260.5 ",
		_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 426 267.5 0 85 19 -split_interval_list ",
		height=0.27778,
		label=split_interval_list,
		pos="426,270",
		rects="375.5,260.5,476.5,279.5",
		width=1.4028];
	scatter_count -> split_interval_list	[_draw_="c 7 -#000000 B 4 426 313.58 426 306.52 426 296.24 426 287.55 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 428.45 287.78 426 280.78 423.55 287.78 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 454 290.6 0 56 13 -scatter_count ",
		label=scatter_count,
		lp="454,292.5",
		pos="e,426,279.26 426,313.58 426,306.52 426,296.24 426,287.55"];
	tumor_bam -> mutect	[_draw_="c 7 -#000000 B 10 1144.15 313.74 1133.13 305.77 1116.57 293.03 1104 280 1096.29 272 1098.69 265.43 1089 260 1047.63 236.84 740.07 \
229.15 604.2 226.87 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 604.45 224.42 597.41 226.76 604.37 229.32 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1127 268.1 0 46 9 -tumor_bam ",
		label=tumor_bam,
		lp="1127,270",
		pos="e,595.9,226.73 1144.1,313.74 1133.1,305.77 1116.6,293.03 1104,280 1096.3,272 1098.7,265.43 1089,260 1047.6,236.84 740.07,229.15 \
604.2,226.87"];
	tumor_bam -> filter	[_draw_="c 7 -#000000 B 10 1155.47 313.7 1154.88 303.61 1154 286.06 1154 271 1154 271 1154 271 1154 134 1154 106.34 752.22 95.29 598.68 92.08 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 598.81 89.63 591.76 91.94 598.71 94.53 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1163.5 200.6 0 19 3 -bam ",
		label=bam,
		lp="1163.5,202.5",
		pos="e,590.25,91.906 1155.5,313.7 1154.9,303.61 1154,286.06 1154,271 1154,271 1154,271 1154,134 1154,106.34 752.22,95.292 598.68,92.08"];
	interval_list -> split_interval_list	[_draw_="c 7 -#000000 B 7 349.71 313.68 356.23 306.07 366.77 294.97 378 288 381.17 286.03 384.6 284.25 388.12 282.65 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 388.96 284.95 394.49 280 387.09 280.42 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 401.5 290.6 0 47 13 -interval_list ",
		label=interval_list,
		lp="401.5,292.5",
		pos="e,395.89,279.42 349.71,313.68 356.23,306.07 366.77,294.97 378,288 381.17,286.03 384.6,284.25 388.12,282.65"];
	split_interval_list -> mutect	[_draw_="c 7 -#000000 B 7 433.92 260.72 439.98 254.88 448.82 247.36 458 243 463.73 240.28 469.88 238 476.15 236.07 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 476.6 238.49 482.67 234.24 475.27 233.78 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 481.5 245.6 0 47 13 -interval_list ",
		label=interval_list,
		lp="481.5,247.5",
		pos="e,484.13,233.83 433.92,260.72 439.98,254.88 448.82,247.36 458,243 463.73,240.28 469.88,238 476.15,236.07"];
	merge	[_draw_="c 7 -#000000 C 7 -#fafad2 P 4 507 170.5 507 189.5 573 189.5 573 170.5 ",
		_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 540 177.5 0 50 9 -vcf merge ",
		height=0.27778,
		label="vcf merge",
		pos="540,180",
		rects="507,170.5,573,189.5",
		width=0.91667];
	index	[_draw_="c 7 -#000000 C 7 -#fafad2 P 4 509 125.5 509 144.5 571 144.5 571 125.5 ",
		_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 540 132.5 0 46 9 -vcf index ",
		height=0.27778,
		label="vcf index",
		pos="540,135",
		rects="509,125.5,571,144.5",
		width=0.86111];
	merge -> index	[_draw_="c 7 -#000000 B 4 540 170.71 540 165.59 540 158.85 540 152.67 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 542.45 152.78 540 145.78 537.55 152.78 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 546.5 155.6 0 13 3 -vcf ",
		label=vcf,
		lp="546.5,157.5",
		pos="e,540,144.27 540,170.71 540,165.59 540,158.85 540,152.67"];
	mutect -> merge	[_draw_="c 7 -#000000 B 4 540 215.71 540 210.59 540 203.85 540 197.67 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 542.45 197.78 540 190.78 537.55 197.78 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 548.5 200.6 0 17 4 -vcfs ",
		label=vcfs,
		lp="548.5,202.5",
		pos="e,540,189.27 540,215.71 540,210.59 540,203.85 540,197.67"];
	index -> filter	[_draw_="c 7 -#000000 B 4 540 125.71 540 120.59 540 113.85 540 107.67 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 542.45 107.78 540 100.78 537.55 107.78 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 546.5 110.6 0 13 3 -vcf ",
		label=vcf,
		lp="546.5,112.5",
		pos="e,540,99.265 540,125.71 540,120.59 540,113.85 540,107.67"];
	filter -> filtered_vcf	[_draw_="c 7 -#000000 B 4 532.29 80.71 526.86 74.88 519.47 66.93 513.13 60.12 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 515.28 58.83 508.72 55.37 511.69 62.17 ",
		pos="e,507.69,54.265 532.29,80.709 526.86,74.879 519.47,66.934 513.13,60.117"];
	filter -> unfiltered_vcf	[_draw_="c 7 -#000000 B 4 547.91 80.71 553.46 74.88 561.04 66.93 567.54 60.12 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 569.02 62.12 572.07 55.36 565.47 58.74 ",
		pos="e,573.12,54.265 547.91,80.709 553.46,74.879 561.04,66.934 567.54,60.117"];
}