digraph workflow { graph [_draw_="c 9 -#fffffe00 C 7 -#eeeeee P 4 0 0 0 773 4968 773 4968 0 ", bb="0,0,4968,773", bgcolor="#eeeeee", clusterrank=local, color=black, dpi=96, fontsize=10, labeljust=left, nodesep=0.05, ranksep=0.22, xdotversion=1.7 ]; node [color=black, fillcolor=lightgoldenrodyellow, fontcolor=black, fontname=Helvetica, fontsize=10, height=0, label="\N", shape=record, style=filled, width=0 ]; edge [arrowsize=0.7, color=black, fontcolor=black, fontname=Helvetica, fontsize=8 ]; subgraph cluster_outputs { graph [_draw_="S 6 -dashed c 7 -#000000 C 7 -#eeeeee P 4 1174 45 1174 100 3298 100 3298 45 ", _ldraw_="F 10 11 -Times-Roman c 7 -#000000 T 1228 52 0 92 16 -Workflow Outputs ", bb="1174,45,3298,100", label="Workflow Outputs", labelloc=b, lheight=0.15, lp="1228,54.5", lwidth=1.28, rank=same, style=dashed ]; strelka_filtered_vcf [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 1847 72.5 1847 91.5 1957 91.5 1957 72.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1902 79.5 0 94 20 -strelka_filtered_vcf ", fillcolor="#94DDF4", height=0.27778, label=strelka_filtered_vcf, pos="1902,82", rects="1847,72.5,1957,91.5", width=1.5278]; 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tumor_bam [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 2056.5 718.5 2056.5 737.5 2129.5 737.5 2129.5 718.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2093 725.5 0 57 9 -tumor_bam ", fillcolor="#94DDF4", height=0.27778, label=tumor_bam, pos="2093,728", rects="2056.5,718.5,2129.5,737.5", width=1.0139]; reference [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 2472.5 718.5 2472.5 737.5 2535.5 737.5 2535.5 718.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2504 725.5 0 47 9 -reference ", fillcolor="#94DDF4", height=0.27778, label=reference, pos="2504,728", rects="2472.5,718.5,2535.5,737.5", width=0.875]; normal_bam [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 1486 718.5 1486 737.5 1564 737.5 1564 718.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1525 725.5 0 62 10 -normal_bam ", fillcolor="#94DDF4", height=0.27778, label=normal_bam, pos="1525,728", rects="1486,718.5,1564,737.5", width=1.0833]; variants_to_table_fields [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 4514.5 718.5 4514.5 737.5 4647.5 737.5 4647.5 718.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 4581 725.5 0 117 24 -variants_to_table_fields ", fillcolor="#94DDF4", height=0.27778, label=variants_to_table_fields, pos="4581,728", rects="4514.5,718.5,4647.5,737.5", width=1.8472]; vep_plugins [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 3050.5 718.5 3050.5 737.5 3125.5 737.5 3125.5 718.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3088 725.5 0 59 11 -vep_plugins ", fillcolor="#94DDF4", height=0.27778, label=vep_plugins, pos="3088,728", rects="3050.5,718.5,3125.5,737.5", width=1.0417]; mutect_artifact_detection_mode [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 246 718.5 246 737.5 422 737.5 422 718.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 334 725.5 0 160 30 -mutect_artifact_detection_mode ", fillcolor="#94DDF4", height=0.27778, label=mutect_artifact_detection_mode, pos="334,728", rects="246,718.5,422,737.5", width=2.4444]; annotate_coding_only [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 3130 718.5 3130 737.5 3254 737.5 3254 718.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3192 725.5 0 108 20 -annotate_coding_only ", fillcolor="#94DDF4", height=0.27778, label=annotate_coding_only, pos="3192,728", rects="3130,718.5,3254,737.5", width=1.7222]; vep_pick [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 3657 718.5 3657 737.5 3717 737.5 3717 718.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3687 725.5 0 44 8 -vep_pick ", fillcolor="#94DDF4", height=0.27778, label=vep_pick, pos="3687,728", rects="3657,718.5,3717,737.5", width=0.83333]; 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interval_list [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 1408 718.5 1408 737.5 1482 737.5 1482 718.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1445 725.5 0 58 13 -interval_list ", fillcolor="#94DDF4", height=0.27778, label=interval_list, pos="1445,728", rects="1408,718.5,1482,737.5", width=1.0278]; filter_mapq0_threshold [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 3850.5 718.5 3850.5 737.5 3979.5 737.5 3979.5 718.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3915 725.5 0 113 22 -filter_mapq0_threshold ", fillcolor="#94DDF4", height=0.27778, label=filter_mapq0_threshold, pos="3915,728", rects="3850.5,718.5,3979.5,737.5", width=1.7917]; readcount_minimum_mapping_quality [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 3258.5 718.5 3258.5 737.5 3463.5 737.5 3463.5 718.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3361 725.5 0 189 33 -readcount_minimum_mapping_quality ", fillcolor="#94DDF4", height=0.27778, label=readcount_minimum_mapping_quality, pos="3361,728", rects="3258.5,718.5,3463.5,737.5", width=2.8472]; 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cle_vcf_filter [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 4136.5 718.5 4136.5 737.5 4215.5 737.5 4215.5 718.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 4176 725.5 0 63 14 -cle_vcf_filter ", fillcolor="#94DDF4", height=0.27778, label=cle_vcf_filter, pos="4176,728", rects="4136.5,718.5,4215.5,737.5", width=1.0972]; dbsnp_vcf [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 980 718.5 980 737.5 1046 737.5 1046 718.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1013 725.5 0 50 9 -dbsnp_vcf ", fillcolor="#94DDF4", height=0.27778, label=dbsnp_vcf, pos="1013,728", rects="980,718.5,1046,737.5", width=0.91667]; synonyms_file [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 2539.5 718.5 2539.5 737.5 2626.5 737.5 2626.5 718.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2583 725.5 0 71 13 -synonyms_file ", fillcolor="#94DDF4", height=0.27778, label=synonyms_file, pos="2583,728", rects="2539.5,718.5,2626.5,737.5", width=1.2083]; varscan_strand_filter [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 1701.5 718.5 1701.5 737.5 1820.5 737.5 1820.5 718.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1761 725.5 0 103 21 -varscan_strand_filter ", fillcolor="#94DDF4", height=0.27778, label=varscan_strand_filter, pos="1761,728", rects="1701.5,718.5,1820.5,737.5", width=1.6528]; filter_gnomADe_maximum_population_allele_frequency [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 4219.5 718.5 4219.5 737.5 4510.5 737.5 4510.5 718.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 4365 725.5 0 275 50 -filter_gnomADe_maximum_population_allele_frequency ", fillcolor="#94DDF4", height=0.27778, label=filter_gnomADe_maximum_population_allele_frequency, pos="4365,728", rects="4219.5,718.5,4510.5,737.5", width=4.0417]; readcount_minimum_base_quality [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 3467.5 718.5 3467.5 737.5 3652.5 737.5 3652.5 718.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3560 725.5 0 169 30 -readcount_minimum_base_quality ", fillcolor="#94DDF4", height=0.27778, label=readcount_minimum_base_quality, pos="3560,728", rects="3467.5,718.5,3652.5,737.5", width=2.5694]; mutect_max_alt_allele_in_normal_fraction [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 16.5 718.5 16.5 737.5 241.5 737.5 241.5 718.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 129 725.5 0 209 40 -mutect_max_alt_allele_in_normal_fraction ", fillcolor="#94DDF4", height=0.27778, label=mutect_max_alt_allele_in_normal_fraction, pos="129,728", rects="16.5,718.5,241.5,737.5", width=3.125]; vep_cache_dir [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 2746 718.5 2746 737.5 2832 737.5 2832 718.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2789 725.5 0 70 13 -vep_cache_dir ", fillcolor="#94DDF4", height=0.27778, label=vep_cache_dir, pos="2789,728", rects="2746,718.5,2832,737.5", width=1.1944]; vep_assembly [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 2836.5 718.5 2836.5 737.5 2923.5 737.5 2923.5 718.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2880 725.5 0 71 12 -vep_assembly ", fillcolor="#94DDF4", height=0.27778, label=vep_assembly, pos="2880,728", rects="2836.5,718.5,2923.5,737.5", width=1.2083]; variants_to_table_genotype_fields [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 4652 718.5 4652 737.5 4836 737.5 4836 718.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 4744 725.5 0 168 33 -variants_to_table_genotype_fields ", fillcolor="#94DDF4", height=0.27778, label=variants_to_table_genotype_fields, pos="4744,728", rects="4652,718.5,4836,737.5", width=2.5556]; pindel_insert_size [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 1050 718.5 1050 737.5 1154 737.5 1154 718.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1102 725.5 0 88 18 -pindel_insert_size ", fillcolor="#94DDF4", height=0.27778, label=pindel_insert_size, pos="1102,728", rects="1050,718.5,1154,737.5", width=1.4444]; custom_gnomad_vcf [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 2928 718.5 2928 737.5 3046 737.5 3046 718.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2987 725.5 0 102 17 -custom_gnomad_vcf ", fillcolor="#94DDF4", height=0.27778, label=custom_gnomad_vcf, pos="2987,728", rects="2928,718.5,3046,737.5", width=1.6389]; varscan_min_var_freq [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 1824.5 718.5 1824.5 737.5 1949.5 737.5 1949.5 718.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1887 725.5 0 109 20 -varscan_min_var_freq ", fillcolor="#94DDF4", height=0.27778, label=varscan_min_var_freq, pos="1887,728", rects="1824.5,718.5,1949.5,737.5", width=1.7361]; vep_to_table_fields [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 4840.5 718.5 4840.5 737.5 4951.5 737.5 4951.5 718.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 4896 725.5 0 95 19 -vep_to_table_fields ", fillcolor="#94DDF4", height=0.27778, label=vep_to_table_fields, pos="4896,728", rects="4840.5,718.5,4951.5,737.5", width=1.5417]; } annotate_variants [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 2852.5 440.5 2852.5 459.5 3025.5 459.5 3025.5 440.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2939 447.5 0 157 32 -Ensembl Variant Effect Predictor ", height=0.27778, label="Ensembl Variant Effect Predictor", pos="2939,450", rects="2852.5,440.5,3025.5,459.5", width=2.4028]; custom_clinvar_vcf -> annotate_variants [_draw_="c 7 -#000000 B 19 2715.65 718.56 2738.3 712.08 2766.54 703.93 2772 702 2800.17 692.04 2834 705.88 2834 676 2834 676 2834 676 2834 \ 606.5 2834 592.16 2833.41 587.17 2841 575 2844.01 570.17 2847.03 571.08 2851 567 2883.02 534.15 2913.87 489.58 2929.11 466.41 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2931.07 467.9 2932.84 460.69 2926.96 465.22 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2879.5 583.1 0 77 18 -custom_clinvar_vcf ", label=custom_clinvar_vcf, lp="2879.5,585", pos="e,2933.7,459.43 2715.7,718.56 2738.3,712.08 2766.5,703.93 2772,702 2800.2,692.04 2834,705.88 2834,676 2834,676 2834,676 2834,606.5 \ 2834,592.16 2833.4,587.17 2841,575 2844,570.17 2847,571.08 2851,567 2883,534.15 2913.9,489.58 2929.1,466.41"]; varscan [_draw_="c 7 -#000000 C 7 -#f3cea1 P 4 1965.5 665.5 1965.5 684.5 2068.5 684.5 2068.5 665.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2017 672.5 0 87 16 -Varscan Workflow ", fillcolor="#F3CEA1", height=0.27778, label="Varscan Workflow", pos="2017,675", rects="1965.5,665.5,2068.5,684.5", width=1.4306]; varscan_p_value -> varscan [_draw_="c 7 -#000000 B 7 2029.5 718.55 2046.77 712.78 2066.55 705.55 2069 702 2072.87 696.39 2071.09 691.94 2066.36 688.41 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2067.65 686.33 2060.33 685.15 2065.32 690.64 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2087 695.6 0 32 7 -p_value ", label=p_value, lp="2087,697.5", pos="e,2059,684.43 2029.5,718.55 2046.8,712.78 2066.5,705.55 2069,702 2072.9,696.39 2071.1,691.94 2066.4,688.41"]; tumor_bam_readcount [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 2572 395.5 2572 414.5 2682 414.5 2682 395.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2627 402.5 0 94 17 -run bam-readcount ", height=0.27778, label="run bam-readcount", pos="2627,405", rects="2572,395.5,2682,414.5", width=1.5278]; tumor_bam -> tumor_bam_readcount [_draw_="c 7 -#000000 B 16 2109.73 718.55 2117 715.28 2125.73 711.88 2134 710 2166.12 702.7 2251.95 715.48 2282 702 2359.14 667.41 2364.77 \ 634.25 2416 567 2441.46 533.59 2432.25 513.62 2463 485 2499.45 451.07 2553.17 428.98 2589.08 417 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2589.57 419.42 2595.47 414.93 2588.06 414.76 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2431.5 560.6 0 19 3 -bam ", label=bam, lp="2431.5,562.5", pos="e,2596.9,414.46 2109.7,718.55 2117,715.28 2125.7,711.88 2134,710 2166.1,702.7 2251.9,715.48 2282,702 2359.1,667.41 2364.8,634.25 \ 2416,567 2441.5,533.59 2432.3,513.62 2463,485 2499.5,451.07 2553.2,428.98 2589.1,417"]; mutect [_draw_="c 7 -#000000 C 7 -#f3cea1 P 4 822 665.5 822 684.5 960 684.5 960 665.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 891 672.5 0 122 24 -mutect parallel workflow ", fillcolor="#F3CEA1", height=0.27778, label="mutect parallel workflow", pos="891,675", rects="822,665.5,960,684.5", width=1.9167]; tumor_bam -> mutect [_draw_="c 7 -#000000 B 13 2077.12 718.55 2069.96 715.19 2061.27 711.72 2053 710 1943.34 687.21 1154.63 724.96 1045 702 1035.06 699.92 1033.8 \ 695.67 1024 693 1006.18 688.14 986.63 684.67 968.13 682.18 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 968.47 679.75 961.22 681.29 967.85 684.61 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1068 695.6 0 46 9 -tumor_bam ", label=tumor_bam, lp="1068,697.5", pos="e,959.72,681.1 2077.1,718.55 2070,715.19 2061.3,711.72 2053,710 1943.3,687.21 1154.6,724.96 1045,702 1035.1,699.92 1033.8,695.67 \ 1024,693 1006.2,688.14 986.63,684.67 968.13,682.18"]; filter_vcf [_draw_="c 7 -#000000 C 7 -#f3cea1 P 4 3685 215.5 3685 234.5 3813 234.5 3813 215.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3749 222.5 0 112 25 -Apply filters to VCF file ", fillcolor="#F3CEA1", height=0.27778, label="Apply filters to VCF file", pos="3749,225", rects="3685,215.5,3813,234.5", width=1.7778]; tumor_bam -> filter_vcf [_draw_="c 7 -#000000 B 28 2109.3 718.58 2116.65 715.22 2125.55 711.75 2134 710 2161.53 704.29 2615.53 715.85 2640 702 2692.12 672.51 2656.56 \ 627.7 2685 575 2687.39 570.58 2690.48 571.35 2693 567 2698.99 556.64 2700 552.97 2700 541 2700 541 2700 541 2700 404 2700 212.02 \ 2781.38 330.99 3092 260 3140.65 248.88 3153.3 247.56 3203 243 3372.42 227.45 3572.51 225.34 3677.09 225.48 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3676.86 227.93 3683.86 225.49 3676.87 223.03 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2723 470.6 0 46 9 -tumor_bam ", label=tumor_bam, lp="2723,472.5", pos="e,3685.4,225.49 2109.3,718.58 2116.6,715.22 2125.5,711.75 2134,710 2161.5,704.29 2615.5,715.85 2640,702 2692.1,672.51 2656.6,627.7 \ 2685,575 2687.4,570.58 2690.5,571.35 2693,567 2699,556.64 2700,552.97 2700,541 2700,541 2700,541 2700,404 2700,212.02 2781.4,330.99 \ 3092,260 3140.7,248.88 3153.3,247.56 3203,243 3372.4,227.45 3572.5,225.34 3677.1,225.48"]; tumor_bam -> varscan [_draw_="c 7 -#000000 B 13 2112.47 718.54 2119.24 715.7 2126.91 712.6 2134 710 2144.95 705.98 2152.12 711.42 2159 702 2161.36 698.77 2161.66 \ 695.99 2159 693 2148.1 680.72 2110.55 676.59 2076.8 675.47 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2076.89 673.02 2069.83 675.28 2076.76 677.92 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2183 695.6 0 46 9 -tumor_bam ", label=tumor_bam, lp="2183,697.5", pos="e,2068.3,675.24 2112.5,718.54 2119.2,715.7 2126.9,712.6 2134,710 2145,705.98 2152.1,711.42 2159,702 2161.4,698.77 2161.7,695.99 \ 2159,693 2148.1,680.72 2110.5,676.59 2076.8,675.47"]; docm [_draw_="c 7 -#000000 C 7 -#f3cea1 P 4 2353.5 665.5 2353.5 684.5 2476.5 684.5 2476.5 665.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2415 672.5 0 107 20 -Detect Docm variants ", fillcolor="#F3CEA1", height=0.27778, label="Detect Docm variants", pos="2415,675", rects="2353.5,665.5,2476.5,684.5", width=1.7083]; tumor_bam -> docm [_draw_="c 7 -#000000 B 13 2109.72 718.52 2117 715.25 2125.73 711.85 2134 710 2170.91 701.75 2268.41 714.8 2304 702 2310.27 699.74 2309.88 \ 695.64 2316 693 2325.29 689 2335.45 685.94 2345.61 683.6 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2345.93 686.03 2352.26 682.18 2344.91 681.24 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2339 695.6 0 46 9 -tumor_bam ", label=tumor_bam, lp="2339,697.5", pos="e,2353.7,681.87 2109.7,718.52 2117,715.25 2125.7,711.85 2134,710 2170.9,701.75 2268.4,714.8 2304,702 2310.3,699.74 2309.9,695.64 \ 2316,693 2325.3,689 2335.4,685.94 2345.6,683.6"]; pindel [_draw_="c 7 -#000000 C 7 -#f3cea1 P 4 1383 665.5 1383 684.5 1517 684.5 1517 665.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1450 672.5 0 118 24 -pindel parallel workflow ", fillcolor="#F3CEA1", height=0.27778, label="pindel parallel workflow", pos="1450,675", rects="1383,665.5,1517,684.5", width=1.8611]; tumor_bam -> pindel [_draw_="c 7 -#000000 B 10 2077.12 718.57 2069.96 715.21 2061.27 711.74 2053 710 2036.58 706.54 1460.79 713.94 1449 702 1446.57 699.54 1445.68 \ 696.22 1445.63 692.79 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1448.05 693.18 1446.62 685.9 1443.2 692.49 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1472 695.6 0 46 9 -tumor_bam ", label=tumor_bam, lp="1472,697.5", pos="e,1446.8,684.4 2077.1,718.57 2070,715.21 2061.3,711.74 2053,710 2036.6,706.54 1460.8,713.94 1449,702 1446.6,699.54 1445.7,696.22 \ 1445.6,692.79"]; strelka [_draw_="c 7 -#000000 C 7 -#f3cea1 P 4 1671.5 665.5 1671.5 684.5 1768.5 684.5 1768.5 665.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1720 672.5 0 81 16 -strelka workflow ", fillcolor="#F3CEA1", height=0.27778, label="strelka workflow", pos="1720,675", rects="1671.5,665.5,1768.5,684.5", width=1.3472]; tumor_bam -> strelka [_draw_="c 7 -#000000 B 10 2077.11 718.61 2069.95 715.26 2061.26 711.79 2053 710 2035.13 706.13 1737.73 714.07 1724 702 1721.26 699.59 1719.84 \ 696.15 1719.18 692.57 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1721.64 692.71 1718.85 685.84 1716.75 692.95 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1747 695.6 0 46 9 -tumor_bam ", label=tumor_bam, lp="1747,697.5", pos="e,1718.8,684.33 2077.1,718.61 2069.9,715.26 2061.3,711.79 2053,710 2035.1,706.13 1737.7,714.07 1724,702 1721.3,699.59 1719.8,696.15 \ 1719.2,692.57"]; reference -> tumor_bam_readcount [_draw_="c 7 -#000000 B 22 2518.6 718.62 2524.97 715.36 2532.65 711.95 2540 710 2562.41 704.06 2627.16 717.93 2644 702 2676.2 671.55 2669.25 \ 645.3 2656 603 2650.18 584.41 2638.22 585.09 2631 567 2626.67 556.14 2627 552.69 2627 541 2627 541 2627 541 2627 449 2627 440.31 \ 2627 430.63 2627 422.65 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2629.45 422.76 2627 415.76 2624.55 422.76 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2663.5 560.6 0 65 15 -reference_fasta ", label=reference_fasta, lp="2663.5,562.5", pos="e,2627,414.24 2518.6,718.62 2525,715.36 2532.7,711.95 2540,710 2562.4,704.06 2627.2,717.93 2644,702 2676.2,671.55 2669.2,645.3 2656,\ 603 2650.2,584.41 2638.2,585.09 2631,567 2626.7,556.14 2627,552.69 2627,541 2627,541 2627,541 2627,449 2627,440.31 2627,430.63 2627,\ 422.65"]; normal_bam_readcount [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 3086 395.5 3086 414.5 3196 414.5 3196 395.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3141 402.5 0 94 17 -run bam-readcount ", height=0.27778, label="run bam-readcount", pos="3141,405", rects="3086,395.5,3196,414.5", width=1.5278]; reference -> normal_bam_readcount [_draw_="c 7 -#000000 B 22 2518.22 718.66 2524.65 715.32 2532.48 711.84 2540 710 2562.68 704.46 2731.74 716.55 2750 702 2759.36 694.54 2757 \ 687.97 2757 676 2757 676 2757 676 2757 606.5 2757 587.79 2795.97 485.32 2810 468 2823.89 450.85 2830.33 447.73 2851 440 2852.32 \ 439.5 2992.88 423.16 3077.8 413.32 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3077.92 415.77 3084.59 412.53 3077.35 410.9 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2802.5 560.6 0 65 15 -reference_fasta ", label=reference_fasta, lp="2802.5,562.5", pos="e,3086.1,412.36 2518.2,718.66 2524.6,715.32 2532.5,711.84 2540,710 2562.7,704.46 2731.7,716.55 2750,702 2759.4,694.54 2757,687.97 \ 2757,676 2757,676 2757,676 2757,606.5 2757,587.79 2796,485.32 2810,468 2823.9,450.85 2830.3,447.73 2851,440 2852.3,439.5 2992.9,\ 423.16 3077.8,413.32"]; reference -> mutect [_draw_="c 7 -#000000 B 13 2490.23 718.55 2483.99 715.2 2476.37 711.73 2469 710 2444.28 704.2 1578.12 712.5 1555 702 1550.13 699.79 1551.85 \ 695.26 1547 693 1534.05 686.98 1139.03 679.96 968.33 677.2 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 968.43 674.75 961.39 677.09 968.35 679.65 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1575 695.6 0 40 9 -reference ", label=reference, lp="1575,697.5", pos="e,959.88,677.07 2490.2,718.55 2484,715.2 2476.4,711.73 2469,710 2444.3,704.2 1578.1,712.5 1555,702 1550.1,699.79 1551.9,695.26 1547,\ 693 1534.1,686.98 1139,679.96 968.33,677.2"]; reference -> filter_vcf [_draw_="c 7 -#000000 B 40 2518.59 718.57 2524.96 715.31 2532.64 711.9 2540 710 2593.47 696.19 2612.13 720.96 2664 702 2675.94 697.64 2678.95 \ 694.84 2687 685 2714.94 650.83 2713.9 636.48 2729 595 2748.99 540.09 2726.57 513.69 2763 468 2779.61 447.17 2790.77 448.54 2816 \ 440 2859.12 425.4 2871.77 428.13 2917 423 2931.93 421.31 3041.69 425.93 3052 415 3071.81 393.98 3063.06 376.69 3052 350 3050.08 \ 345.35 3045.92 346.65 3044 342 3042.47 338.3 3042.41 336.67 3044 333 3069.03 275.4 3104.35 276.3 3165 260 3259.51 234.6 3542.68 \ 228.18 3676.9 226.55 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3676.65 229 3683.62 226.47 3676.6 224.1 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2783 470.6 0 40 9 -reference ", label=reference, lp="2783,472.5", pos="e,3685.1,226.45 2518.6,718.57 2525,715.31 2532.6,711.9 2540,710 2593.5,696.19 2612.1,720.96 2664,702 2675.9,697.64 2679,694.84 2687,\ 685 2714.9,650.83 2713.9,636.48 2729,595 2749,540.09 2726.6,513.69 2763,468 2779.6,447.17 2790.8,448.54 2816,440 2859.1,425.4 2871.8,\ 428.13 2917,423 2931.9,421.31 3041.7,425.93 3052,415 3071.8,393.98 3063.1,376.69 3052,350 3050.1,345.35 3045.9,346.65 3044,342 3042.5,\ 338.3 3042.4,336.67 3044,333 3069,275.4 3104.3,276.3 3165,260 3259.5,234.6 3542.7,228.18 3676.9,226.55"]; reference -> varscan [_draw_="c 7 -#000000 B 7 2523.06 718.56 2535.79 711.81 2548.73 702.02 2540 693 2538.01 690.94 2213.46 681.54 2076.69 677.67 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2076.93 675.23 2069.86 677.48 2076.79 680.13 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2562 695.6 0 40 9 -reference ", label=reference, lp="2562,697.5", pos="e,2068.3,677.44 2523.1,718.56 2535.8,711.81 2548.7,702.02 2540,693 2538,690.94 2213.5,681.54 2076.7,677.67"]; reference -> docm [_draw_="c 7 -#000000 B 10 2519.02 718.68 2525.33 715.51 2532.85 712.15 2540 710 2564.91 702.52 2613.51 712.23 2596 693 2594.05 690.86 2534.8 \ 685.58 2484.61 681.47 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2485.01 679.04 2477.84 680.92 2484.62 683.93 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2619 695.6 0 40 9 -reference ", label=reference, lp="2619,697.5", pos="e,2476.3,680.79 2519,718.68 2525.3,715.51 2532.9,712.15 2540,710 2564.9,702.52 2613.5,712.23 2596,693 2594.1,690.86 2534.8,685.58 \ 2484.6,681.47"]; reference -> pindel [_draw_="c 7 -#000000 B 16 2490.22 718.6 2483.97 715.26 2476.35 711.78 2469 710 2431.08 700.82 2155.3 713.42 2118 702 2110.93 699.83 2111.08 \ 695.15 2104 693 2080.93 685.99 1694.1 685.72 1670 685 1621.82 683.57 1567.73 681.37 1525.24 679.5 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1525.51 677.06 1518.41 679.19 1525.3 681.95 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2138 695.6 0 40 9 -reference ", label=reference, lp="2138,697.5", pos="e,1516.9,679.13 2490.2,718.6 2484,715.26 2476.4,711.78 2469,710 2431.1,700.82 2155.3,713.42 2118,702 2110.9,699.83 2111.1,695.15 \ 2104,693 2080.9,685.99 1694.1,685.72 1670,685 1621.8,683.57 1567.7,681.37 1525.2,679.5"]; reference -> annotate_variants [_draw_="c 7 -#000000 B 22 2518.6 718.61 2524.97 715.34 2532.65 711.93 2540 710 2586.98 697.64 2602.52 716.1 2649 702 2663.67 697.55 2670.52 \ 697.76 2679 685 2706.24 644 2666.26 616.96 2692 575 2695.35 569.54 2698.81 570.76 2704 567 2735.56 544.18 2739.03 532.04 2773 513 \ 2814.12 489.96 2865.48 472.29 2900.1 461.81 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2900.62 464.21 2906.63 459.87 2899.23 459.52 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2712 583.1 0 40 9 -reference ", label=reference, lp="2712,585", pos="e,2908.1,459.44 2518.6,718.61 2525,715.34 2532.6,711.93 2540,710 2587,697.64 2602.5,716.1 2649,702 2663.7,697.55 2670.5,697.76 2679,\ 685 2706.2,644 2666.3,616.96 2692,575 2695.4,569.54 2698.8,570.76 2704,567 2735.6,544.18 2739,532.04 2773,513 2814.1,489.96 2865.5,\ 472.29 2900.1,461.81"]; add_docm_variants [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 2464.5 485.5 2464.5 504.5 2619.5 504.5 2619.5 485.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2542 492.5 0 139 26 -CombineVariants (GATK 3.6) ", height=0.27778, label="CombineVariants (GATK 3.6)", pos="2542,495", rects="2464.5,485.5,2619.5,504.5", width=2.1528]; reference -> add_docm_variants [_draw_="c 7 -#000000 B 13 2518.6 718.62 2524.97 715.36 2532.65 711.95 2540 710 2551.2 707.03 2636.13 710.5 2644 702 2647.79 697.9 2648.44 \ 687.58 2641 665 2620.58 603.04 2575.16 539.03 2553.69 510.84 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2555.68 509.41 2549.46 505.37 2551.8 512.41 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2637 605.6 0 40 9 -reference ", label=reference, lp="2637,607.5", pos="e,2548.5,504.17 2518.6,718.62 2525,715.36 2532.7,711.95 2540,710 2551.2,707.03 2636.1,710.5 2644,702 2647.8,697.9 2648.4,687.58 \ 2641,665 2620.6,603.04 2575.2,539.03 2553.7,510.84"]; reference -> strelka [_draw_="c 7 -#000000 B 16 2489.83 718.62 2483.64 715.36 2476.17 711.95 2469 710 2447.06 704.04 2387.36 712.12 2367 702 2362.21 699.62 2363.86 \ 695.24 2359 693 2339.07 683.81 1985.94 685.63 1964 685 1899.71 683.16 1825.92 680.34 1776.47 678.35 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1776.75 675.91 1769.65 678.07 1776.55 680.8 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2387 695.6 0 40 9 -reference ", label=reference, lp="2387,697.5", pos="e,1768.1,678.01 2489.8,718.62 2483.6,715.36 2476.2,711.95 2469,710 2447.1,704.04 2387.4,712.12 2367,702 2362.2,699.62 2363.9,695.24 \ 2359,693 2339.1,683.81 1985.9,685.63 1964,685 1899.7,683.16 1825.9,680.34 1776.5,678.35"]; combine [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 1843.5 620.5 1843.5 639.5 1998.5 639.5 1998.5 620.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1921 627.5 0 139 26 -CombineVariants (GATK 3.6) ", height=0.27778, label="CombineVariants (GATK 3.6)", pos="1921,630", rects="1843.5,620.5,1998.5,639.5", width=2.1528]; reference -> combine [_draw_="c 7 -#000000 B 16 2518.6 718.63 2524.97 715.37 2532.65 711.96 2540 710 2550.77 707.13 2632.44 710.19 2640 702 2642.71 699.06 2642.57 \ 696.06 2640 693 2637.08 689.53 2483.51 665.53 2479 665 2312.48 645.51 2116.6 636.84 2006.82 633.26 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2007 630.82 1999.93 633.04 2006.85 635.72 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2620 673.1 0 40 9 -reference ", label=reference, lp="2620,675", pos="e,1998.4,632.99 2518.6,718.63 2525,715.37 2532.7,711.96 2540,710 2550.8,707.13 2632.4,710.19 2640,702 2642.7,699.06 2642.6,696.06 \ 2640,693 2637.1,689.53 2483.5,665.53 2479,665 2312.5,645.51 2116.6,636.84 2006.8,633.26"]; variants_to_table [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 3419.5 72.5 3419.5 91.5 3560.5 91.5 3560.5 72.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3490 79.5 0 125 25 -SelectVariants (GATK 3.6) ", height=0.27778, label="SelectVariants (GATK 3.6)", pos="3490,82", rects="3419.5,72.5,3560.5,91.5", width=1.9583]; reference -> variants_to_table [_draw_="c 7 -#000000 B 25 2518.22 718.65 2524.65 715.32 2532.48 711.83 2540 710 2586.88 698.58 2708.99 706.84 2757 702 2960.68 681.48 3044.17 \ 721.65 3205 595 3220.4 582.87 3216.45 573.06 3229 558 3306.88 464.52 3366.1 474.75 3428 370 3440.61 348.66 3442 340.79 3442 316 \ 3442 316 3442 316 3442 134 3442 117.89 3454.85 104.8 3467.26 95.91 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3468.28 98.17 3472.76 92.26 3465.57 94.09 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3431 403.1 0 40 9 -reference ", label=reference, lp="3431,405", pos="e,3474,91.418 2518.2,718.65 2524.6,715.32 2532.5,711.83 2540,710 2586.9,698.58 2709,706.84 2757,702 2960.7,681.48 3044.2,721.65 \ 3205,595 3220.4,582.87 3216.5,573.06 3229,558 3306.9,464.52 3366.1,474.75 3428,370 3440.6,348.66 3442,340.79 3442,316 3442,316 3442,\ 316 3442,134 3442,117.89 3454.9,104.8 3467.3,95.914"]; normal_bam -> normal_bam_readcount [_draw_="c 7 -#000000 B 25 1542.13 718.54 1549.84 715.18 1559.17 711.72 1568 710 1626.46 698.64 2580.9 709.37 2640 702 2688.14 696 2746 724.51 \ 2746 676 2746 676 2746 676 2746 584 2746 572.44 2739.52 566.82 2747 558 2887.6 392.32 3088.61 628.35 3226 460 3238.24 445 3220.42 \ 431.46 3203 423 3198.39 420.76 3193.43 418.78 3188.41 417.03 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3189.35 414.76 3181.94 414.94 3187.85 419.42 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2756.5 560.6 0 19 3 -bam ", label=bam, lp="2756.5,562.5", pos="e,3180.5,414.48 1542.1,718.54 1549.8,715.18 1559.2,711.72 1568,710 1626.5,698.64 2580.9,709.37 2640,702 2688.1,696 2746,724.51 2746,\ 676 2746,676 2746,676 2746,584 2746,572.44 2739.5,566.82 2747,558 2887.6,392.32 3088.6,628.35 3226,460 3238.2,445 3220.4,431.46 \ 3203,423 3198.4,420.76 3193.4,418.78 3188.4,417.03"]; normal_bam -> mutect [_draw_="c 7 -#000000 B 13 1507.86 718.58 1500.15 715.23 1490.82 711.75 1482 710 1426.85 699.04 1029.2 720.2 976 702 969.69 699.84 970.04 \ 695.82 964 693 958.93 690.64 953.5 688.59 947.98 686.81 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 948.71 684.48 941.31 684.84 947.32 689.17 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1001.5 695.6 0 51 10 -normal_bam ", label=normal_bam, lp="1001.5,697.5", pos="e,939.86,684.41 1507.9,718.58 1500.2,715.23 1490.8,711.75 1482,710 1426.8,699.04 1029.2,720.2 976,702 969.69,699.84 970.04,695.82 \ 964,693 958.93,690.64 953.5,688.59 947.98,686.81"]; normal_bam -> varscan [_draw_="c 7 -#000000 B 13 1543.05 718.55 1550.6 715.37 1559.57 712.02 1568 710 1604.47 701.24 1616.37 713.71 1652 702 1659.39 699.57 1659.56 \ 695.26 1667 693 1680.6 688.88 1860.82 681.71 1957.18 678.15 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1957.25 680.6 1964.15 677.89 1957.07 675.7 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1692.5 695.6 0 51 10 -normal_bam ", label=normal_bam, lp="1692.5,697.5", pos="e,1965.7,677.83 1543,718.55 1550.6,715.37 1559.6,712.02 1568,710 1604.5,701.24 1616.4,713.71 1652,702 1659.4,699.57 1659.6,695.26 \ 1667,693 1680.6,688.88 1860.8,681.71 1957.2,678.15"]; normal_bam -> docm [_draw_="c 7 -#000000 B 13 1542.15 718.62 1549.86 715.27 1559.19 711.79 1568 710 1603.07 702.87 1857.54 717.07 1890 702 1894.85 699.75 1893.15 \ 695.27 1898 693 1903 690.66 2205.56 681.88 2345.45 677.94 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2345.17 680.4 2352.1 677.75 2345.03 675.5 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1923.5 695.6 0 51 10 -normal_bam ", label=normal_bam, lp="1923.5,697.5", pos="e,2353.6,677.71 1542.1,718.62 1549.9,715.27 1559.2,711.79 1568,710 1603.1,702.87 1857.5,717.07 1890,702 1894.9,699.75 1893.2,695.27 \ 1898,693 1903,690.66 2205.6,681.88 2345.4,677.94"]; normal_bam -> pindel [_draw_="c 7 -#000000 B 10 1507.84 718.67 1500.13 715.33 1490.8 711.84 1482 710 1470.14 707.51 1272.41 710.73 1264 702 1246.74 684.09 1316.12 \ 678.29 1375 676.53 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1374.78 678.99 1381.71 676.35 1374.65 674.09 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1289.5 695.6 0 51 10 -normal_bam ", label=normal_bam, lp="1289.5,697.5", pos="e,1383.2,676.31 1507.8,718.67 1500.1,715.33 1490.8,711.84 1482,710 1470.1,707.51 1272.4,710.73 1264,702 1246.7,684.09 1316.1,678.29 \ 1375,676.53"]; normal_bam -> strelka [_draw_="c 7 -#000000 B 7 1511.42 718.55 1501.65 711.45 1491.43 701.18 1499 693 1509.96 681.17 1601.31 677.54 1663.08 676.45 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1663.12 678.9 1670.07 676.34 1663.04 674 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1524.5 695.6 0 51 10 -normal_bam ", label=normal_bam, lp="1524.5,697.5", pos="e,1671.6,676.31 1511.4,718.55 1501.7,711.45 1491.4,701.18 1499,693 1510,681.17 1601.3,677.54 1663.1,676.45"]; variants_to_table_fields -> variants_to_table [_draw_="c 7 -#000000 B 10 4552.12 718.53 4532.84 710.9 4511 697.5 4511 676 4511 676 4511 676 4511 134 4511 86.86 3807.63 82.84 3568.49 82.83 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3568.69 80.38 3561.69 82.83 3568.69 85.28 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 4522.5 403.1 0 23 6 -fields ", label=fields, lp="4522.5,405", pos="e,3560.2,82.835 4552.1,718.53 4532.8,710.9 4511,697.5 4511,676 4511,676 4511,676 4511,134 4511,86.862 3807.6,82.839 3568.5,82.834"]; vep_plugins -> annotate_variants [_draw_="c 7 -#000000 B 10 3096.23 718.79 3104.81 709.33 3117 692.91 3117 676 3117 676 3117 676 3117 494 3117 474.51 3076.18 463.83 3033.63 \ 457.98 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3034.15 455.58 3026.89 457.11 3033.52 460.44 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3132.5 583.1 0 31 7 -plugins ", label=plugins, lp="3132.5,585", pos="e,3025.4,456.91 3096.2,718.79 3104.8,709.33 3117,692.91 3117,676 3117,676 3117,676 3117,494 3117,474.51 3076.2,463.83 3033.6,457.98"]; mutect_artifact_detection_mode -> mutect [_draw_="c 7 -#000000 B 7 350.89 718.62 368.43 710.39 396.9 698.31 423 693 495.38 678.28 700.79 675.89 813.91 675.75 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 813.72 678.2 820.72 675.74 813.71 673.3 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 473 695.6 0 100 23 -artifact_detection_mode ", label=artifact_detection_mode, lp="473,697.5", pos="e,822.23,675.74 350.89,718.62 368.43,710.39 396.9,698.31 423,693 495.38,678.28 700.79,675.89 813.91,675.75"]; annotate_coding_only -> annotate_variants [_draw_="c 7 -#000000 B 22 3181 718.52 3170.42 709.32 3156 693.56 3156 676 3156 676 3156 676 3156 606.5 3156 592.06 3155.82 587.14 3148 575 \ 3144.92 570.22 3140.98 571.85 3138 567 3118.54 535.27 3141.68 515.95 3121 485 3113.54 473.83 3108.61 472.64 3096 468 3083.87 463.54 \ 3059.4 460.06 3033.31 457.44 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3033.88 455.04 3026.68 456.8 3033.41 459.91 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3179.5 583.1 0 49 11 -coding_only ", label=coding_only, lp="3179.5,585", pos="e,3025.2,456.66 3181,718.52 3170.4,709.32 3156,693.56 3156,676 3156,676 3156,676 3156,606.5 3156,592.06 3155.8,587.14 3148,575 3144.9,\ 570.22 3141,571.85 3138,567 3118.5,535.27 3141.7,515.95 3121,485 3113.5,473.83 3108.6,472.64 3096,468 3083.9,463.54 3059.4,460.06 \ 3033.3,457.44"]; vep_pick -> annotate_variants [_draw_="c 7 -#000000 B 16 3672.91 718.53 3666.96 715.34 3659.84 712 3653 710 3618.25 699.85 3329 712.2 3329 676 3329 676 3329 676 3329 584 \ 3329 465.05 3123.57 471.72 3109 468 3084.99 461.88 3058.54 457.94 3033.8 455.41 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3034.2 452.99 3026.99 454.75 3033.72 457.87 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3337.5 583.1 0 17 4 -pick ", label=pick, lp="3337.5,585", pos="e,3025.5,454.61 3672.9,718.53 3667,715.34 3659.8,712 3653,710 3618.3,699.85 3329,712.2 3329,676 3329,676 3329,676 3329,584 3329,\ 465.05 3123.6,471.72 3109,468 3085,461.88 3058.5,457.94 3033.8,455.41"]; filter_minimum_depth -> filter_vcf [_draw_="c 7 -#000000 B 13 3784 718.7 3784 708.6 3784 691.05 3784 676 3784 676 3784 676 3784 269 3784 257.03 3784.19 252.57 3777 243 3776.13 \ 241.84 3775.16 240.75 3774.11 239.71 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3775.69 237.84 3768.69 235.4 3772.64 241.67 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3828 470.6 0 88 20 -filter_minimum_depth ", label=filter_minimum_depth, lp="3828,472.5", pos="e,3767.5,234.46 3784,718.7 3784,708.6 3784,691.05 3784,676 3784,676 3784,676 3784,269 3784,257.03 3784.2,252.57 3777,243 3776.1,\ 241.84 3775.2,240.75 3774.1,239.71"]; filter_docm_variants -> docm [_draw_="c 7 -#000000 B 7 2382.33 718.51 2391.84 714.82 2401.17 709.54 2408 702 2410.4 699.35 2411.99 695.96 2413.04 692.5 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2415.44 693.02 2414.4 685.67 2410.63 692.06 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2453 695.6 0 82 20 -filter_docm_variants ", label=filter_docm_variants, lp="2453,697.5", pos="e,2414.7,684.19 2382.3,718.51 2391.8,714.82 2401.2,709.54 2408,702 2410.4,699.35 2412,695.96 2413,692.5"]; varscan_min_coverage -> varscan [_draw_="c 7 -#000000 B 13 1664.09 718.51 1675.89 715.5 1689.5 712.3 1702 710 1730.63 704.73 1740 712.88 1767 702 1773.18 699.51 1772.75 \ 695.33 1779 693 1810.5 681.24 1897.78 677.56 1957.41 676.44 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1957.17 678.89 1964.12 676.32 1957.08 673.99 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1808 695.6 0 58 12 -min_coverage ", label=min_coverage, lp="1808,697.5", pos="e,1965.6,676.3 1664.1,718.51 1675.9,715.5 1689.5,712.3 1702,710 1730.6,704.73 1740,712.88 1767,702 1773.2,699.51 1772.8,695.33 1779,\ 693 1810.5,681.24 1897.8,677.56 1957.4,676.44"]; mutect_max_alt_alleles_in_normal_count -> mutect [_draw_="c 7 -#000000 B 7 529.94 718.64 525.2 711.01 520.42 699.89 527 693 536.75 682.78 710.18 678.54 814.08 676.92 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 813.89 679.37 820.85 676.82 813.81 674.47 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 593.5 695.6 0 133 31 -max_alt_alleles_in_normal_count ", label=max_alt_alleles_in_normal_count, lp="593.5,697.5", pos="e,822.36,676.79 529.94,718.64 525.2,711.01 520.42,699.89 527,693 536.75,682.78 710.18,678.54 814.08,676.92"]; interval_list -> mutect [_draw_="c 7 -#000000 B 10 1428.7 718.58 1421.35 715.23 1412.45 711.76 1404 710 1377.67 704.53 945.04 711.82 920 702 918.16 701.28 911.94 \ 695.79 905.74 690.03 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 907.58 688.4 900.8 685.4 904.22 691.97 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 943.5 695.6 0 47 13 -interval_list ", label=interval_list, lp="943.5,697.5", pos="e,899.69,684.36 1428.7,718.58 1421.4,715.23 1412.5,711.76 1404,710 1377.7,704.53 945.04,711.82 920,702 918.16,701.28 911.94,695.79 \ 905.74,690.03"]; interval_list -> varscan [_draw_="c 7 -#000000 B 13 1461.75 718.63 1469.02 715.37 1477.75 711.96 1486 710 1509.85 704.35 1574.02 712.85 1596 702 1600.8 699.63 1599.16 \ 695.29 1604 693 1607.94 691.13 1844.02 682.3 1957.43 678.16 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1957.29 680.61 1964.19 677.91 1957.11 675.72 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1627.5 695.6 0 47 13 -interval_list ", label=interval_list, lp="1627.5,697.5", pos="e,1965.7,677.85 1461.7,718.63 1469,715.37 1477.8,711.96 1486,710 1509.8,704.35 1574,712.85 1596,702 1600.8,699.63 1599.2,695.29 \ 1604,693 1607.9,691.13 1844,682.3 1957.4,678.16"]; interval_list -> docm [_draw_="c 7 -#000000 B 13 1461.31 718.61 1468.65 715.26 1477.56 711.78 1486 710 1523.84 702.01 1798.9 718.25 1834 702 1838.86 699.75 1837.15 \ 695.26 1842 693 1844.82 691.68 2193.29 682.04 2345.35 677.89 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2345.32 680.34 2352.25 677.7 2345.19 675.44 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1865.5 695.6 0 47 13 -interval_list ", label=interval_list, lp="1865.5,697.5", pos="e,2353.8,677.66 1461.3,718.61 1468.7,715.26 1477.6,711.78 1486,710 1523.8,702.01 1798.9,718.25 1834,702 1838.9,699.75 1837.2,695.26 \ 1842,693 1844.8,691.68 2193.3,682.04 2345.4,677.89"]; interval_list -> pindel [_draw_="c 7 -#000000 B 13 1428.69 718.64 1421.34 715.3 1412.44 711.82 1404 710 1389.87 706.96 1154.06 712.37 1144 702 1141.22 699.13 1141.25 \ 695.91 1144 693 1151.85 684.7 1286.84 679.89 1374.88 677.62 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1374.8 680.07 1381.73 677.44 1374.67 675.17 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1167.5 695.6 0 47 13 -interval_list ", label=interval_list, lp="1167.5,697.5", pos="e,1383.2,677.41 1428.7,718.64 1421.3,715.3 1412.4,711.82 1404,710 1389.9,706.96 1154.1,712.37 1144,702 1141.2,699.13 1141.3,695.91 \ 1144,693 1151.8,684.7 1286.8,679.89 1374.9,677.62"]; interval_list -> strelka [_draw_="c 7 -#000000 B 10 1424.35 718.56 1408.49 711.99 1389.11 703.7 1388 702 1385.81 698.65 1385.24 695.9 1388 693 1389.17 691.77 1568.73 \ 683.13 1663.26 678.66 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1663.19 681.12 1670.07 678.34 1662.96 676.22 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1411.5 695.6 0 47 13 -interval_list ", label=interval_list, lp="1411.5,697.5", pos="e,1671.6,678.27 1424.3,718.56 1408.5,711.99 1389.1,703.7 1388,702 1385.8,698.65 1385.2,695.9 1388,693 1389.2,691.77 1568.7,683.13 \ 1663.3,678.66"]; filter_mapq0_threshold -> filter_vcf [_draw_="c 7 -#000000 B 10 3910.35 718.62 3905.32 708.74 3898 691.68 3898 676 3898 676 3898 676 3898 269 3898 251.34 3858.88 240.49 3820.73 \ 234.11 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3821.42 231.73 3814.12 233.05 3820.64 236.57 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3945 470.6 0 94 22 -filter_mapq0_threshold ", label=filter_mapq0_threshold, lp="3945,472.5", pos="e,3812.6,232.81 3910.4,718.62 3905.3,708.74 3898,691.68 3898,676 3898,676 3898,676 3898,269 3898,251.34 3858.9,240.49 3820.7,234.11"]; readcount_minimum_mapping_quality -> tumor_bam_readcount [_draw_="c 7 -#000000 B 19 3315.23 718.54 3294.51 714.28 3269.82 708.62 3248 702 3122.49 663.95 3076.16 675.98 2973 595 2964.47 588.3 2967.74 \ 581.44 2959 575 2949.61 568.08 2945.02 570.83 2934 567 2826.8 529.69 2789.72 539.54 2695 477 2671.53 461.5 2650.1 436.54 2637.81 \ 420.72 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2639.93 419.46 2633.75 415.37 2636.03 422.42 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2977.5 560.6 0 87 19 -min_mapping_quality ", label=min_mapping_quality, lp="2977.5,562.5", pos="e,2632.8,414.16 3315.2,718.54 3294.5,714.28 3269.8,708.62 3248,702 3122.5,663.95 3076.2,675.98 2973,595 2964.5,588.3 2967.7,581.44 \ 2959,575 2949.6,568.08 2945,570.83 2934,567 2826.8,529.69 2789.7,539.54 2695,477 2671.5,461.5 2650.1,436.54 2637.8,420.72"]; readcount_minimum_mapping_quality -> normal_bam_readcount [_draw_="c 7 -#000000 B 13 3319.42 718.55 3282.38 709.8 3234 694.77 3234 676 3234 676 3234 676 3234 584 3234 538.9 3175.58 495.85 3158 460 \ 3152.12 448 3147.69 433.52 3144.83 422.58 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3147.22 422.02 3143.16 415.81 3142.46 423.2 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3274.5 560.6 0 87 19 -min_mapping_quality ", label=min_mapping_quality, lp="3274.5,562.5", pos="e,3142.8,414.35 3319.4,718.55 3282.4,709.8 3234,694.77 3234,676 3234,676 3234,676 3234,584 3234,538.9 3175.6,495.85 3158,460 3152.1,\ 448 3147.7,433.52 3144.8,422.58"]; varscan_max_normal_freq -> varscan [_draw_="c 7 -#000000 B 7 2209.84 718.6 2211.85 710.93 2213.21 699.8 2207 693 2198.25 683.43 2129.09 679.21 2076.71 677.37 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2077.05 674.93 2069.97 677.15 2076.89 679.83 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2246 695.6 0 70 15 -max_normal_freq ", label=max_normal_freq, lp="2246,697.5", pos="e,2068.5,677.1 2209.8,718.6 2211.9,710.93 2213.2,699.8 2207,693 2198.2,683.43 2129.1,679.21 2076.7,677.37"]; strelka_exome_mode -> strelka [_draw_="c 7 -#000000 B 10 1211.08 718.75 1204.77 711.2 1198.05 700.13 1205 693 1211.09 686.75 1510.28 685.31 1519 685 1567.72 683.29 1623.07 \ 680.77 1663.33 678.83 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1663.3 681.28 1670.17 678.5 1663.06 676.39 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1232.5 695.6 0 55 10 -exome_mode ", label=exome_mode, lp="1232.5,697.5", pos="e,1671.7,678.43 1211.1,718.75 1204.8,711.2 1198,700.13 1205,693 1211.1,686.75 1510.3,685.31 1519,685 1567.7,683.29 1623.1,680.77 \ 1663.3,678.83"]; docm_vcf -> docm [_draw_="c 7 -#000000 B 13 2452.62 718.5 2458.64 715.6 2465.54 712.46 2472 710 2483.69 705.54 2491.51 712.03 2499 702 2501.39 698.79 2501.53 \ 696.1 2499 693 2496.41 689.83 2491.04 687.23 2484.21 685.12 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2485.16 682.83 2477.76 683.39 2483.89 687.57 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2519.5 695.6 0 39 8 -docm_vcf ", label=docm_vcf, lp="2519.5,697.5", pos="e,2476.3,683 2452.6,718.5 2458.6,715.6 2465.5,712.46 2472,710 2483.7,705.54 2491.5,712.03 2499,702 2501.4,698.79 2501.5,696.1 2499,\ 693 2496.4,689.83 2491,687.23 2484.2,685.12"]; mutect_scatter_count -> mutect [_draw_="c 7 -#000000 B 7 684.56 718.62 669.15 712.4 654.48 703.26 664 693 674.21 682 752.25 678.07 814.02 676.69 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 813.77 679.14 820.72 676.55 813.67 674.25 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 692 695.6 0 56 13 -scatter_count ", label=scatter_count, lp="692,697.5", pos="e,822.23,676.52 684.56,718.62 669.15,712.4 654.48,703.26 664,693 674.21,682 752.25,678.07 814.02,676.69"]; panel_of_normals_vcf -> mutect [_draw_="c 7 -#000000 B 13 807.58 718.53 796.44 715.6 783.7 712.44 772 710 760.98 707.71 729.3 710.56 722 702 719.4 698.96 719.32 695.97 \ 722 693 728.47 685.85 772.43 681.57 813.9 679.09 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 813.78 681.55 820.63 678.71 813.5 676.66 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 766 695.6 0 88 20 -panel_of_normals_vcf ", label=panel_of_normals_vcf, lp="766,697.5", pos="e,822.14,678.62 807.58,718.53 796.44,715.6 783.7,712.44 772,710 760.98,707.71 729.3,710.56 722,702 719.4,698.96 719.32,695.97 722,\ 693 728.47,685.85 772.43,681.57 813.9,679.09"]; filter_somatic_llr_threshold -> filter_vcf [_draw_="c 7 -#000000 B 10 4049.77 718.79 4041.19 709.33 4029 692.91 4029 676 4029 676 4029 676 4029 269 4029 247.99 3904.24 235.87 3821.28 \ 230.13 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3821.55 227.69 3814.4 229.67 3821.22 232.58 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 4083.5 470.6 0 109 28 -filter_somatic_llr_threshold ", label=filter_somatic_llr_threshold, lp="4083.5,472.5", pos="e,3812.9,229.56 4049.8,718.79 4041.2,709.33 4029,692.91 4029,676 4029,676 4029,676 4029,269 4029,247.99 3904.2,235.87 3821.3,230.13"]; cosmic_vcf -> mutect [_draw_="c 7 -#000000 B 10 923.71 718.52 916.87 715.32 908.73 711.99 901 710 882.41 705.22 827.93 716.19 815 702 809.65 696.13 810.44 691.58 \ 814.91 688.07 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 815.96 690.28 821.01 684.84 813.67 685.95 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 837.5 695.6 0 45 10 -cosmic_vcf ", label=cosmic_vcf, lp="837.5,697.5", pos="e,822.34,684.13 923.71,718.52 916.87,715.32 908.73,711.99 901,710 882.41,705.22 827.93,716.19 815,702 809.65,696.13 810.44,691.58 \ 814.91,688.07"]; strelka_cpu_reserved -> strelka [_draw_="c 7 -#000000 B 10 1336.11 718.78 1329.82 711.24 1323.11 700.19 1330 693 1337.27 685.41 1508.5 685.46 1519 685 1567.71 682.88 1623.05 \ 680.4 1663.32 678.58 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1663.28 681.03 1670.16 678.27 1663.06 676.13 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1357.5 695.6 0 55 12 -cpu_reserved ", label=cpu_reserved, lp="1357.5,697.5", pos="e,1671.7,678.2 1336.1,718.78 1329.8,711.24 1323.1,700.19 1330,693 1337.3,685.41 1508.5,685.46 1519,685 1567.7,682.88 1623.1,680.4 \ 1663.3,678.58"]; cle_vcf_filter -> filter_vcf [_draw_="c 7 -#000000 B 10 4171.9 718.56 4167.46 708.62 4161 691.51 4161 676 4161 676 4161 676 4161 269 4161 235.25 3939.41 227.87 3821.25 \ 226.34 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3821.47 223.89 3814.44 226.26 3821.41 228.79 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 4193.5 470.6 0 65 17 -do_cle_vcf_filter ", label=do_cle_vcf_filter, lp="4193.5,472.5", pos="e,3812.9,226.24 4171.9,718.56 4167.5,708.62 4161,691.51 4161,676 4161,676 4161,676 4161,269 4161,235.25 3939.4,227.87 3821.2,226.34"]; dbsnp_vcf -> mutect [_draw_="c 7 -#000000 B 10 997.97 718.62 991.42 715.36 983.53 711.94 976 710 964.46 707.02 877.11 710.74 869 702 865.43 698.16 866.98 693.86 \ 870.52 689.88 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 872.01 691.83 875.64 685.36 868.77 688.15 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 890 695.6 0 42 9 -dbsnp_vcf ", label=dbsnp_vcf, lp="890,697.5", pos="e,876.78,684.36 997.97,718.62 991.42,715.36 983.53,711.94 976,710 964.46,707.02 877.11,710.74 869,702 865.43,698.16 866.98,693.86 \ 870.52,689.88"]; synonyms_file -> annotate_variants [_draw_="c 7 -#000000 B 28 2602.73 718.61 2611.27 715.35 2621.47 711.94 2631 710 2645.18 707.11 2749.79 711.15 2761 702 2770.27 694.43 2768 \ 687.97 2768 676 2768 676 2768 676 2768 606.5 2768 592.16 2764.38 584.64 2775 575 2796.55 555.43 2815.04 581.97 2840 567 2857.23 \ 556.66 2854.05 546.16 2866 530 2881.07 509.63 2883.71 503.52 2901 485 2907.52 478.01 2915.31 470.87 2922.12 464.94 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2923.65 466.86 2927.39 460.46 2920.47 463.14 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2804 583.1 0 58 13 -synonyms_file ", label=synonyms_file, lp="2804,585", pos="e,2928.5,459.48 2602.7,718.61 2611.3,715.35 2621.5,711.94 2631,710 2645.2,707.11 2749.8,711.15 2761,702 2770.3,694.43 2768,687.97 \ 2768,676 2768,676 2768,676 2768,606.5 2768,592.16 2764.4,584.64 2775,575 2796.5,555.43 2815,581.97 2840,567 2857.2,556.66 2854,546.16 \ 2866,530 2881.1,509.63 2883.7,503.52 2901,485 2907.5,478.01 2915.3,470.87 2922.1,464.94"]; varscan_strand_filter -> varscan [_draw_="c 7 -#000000 B 13 1788.15 718.53 1799.44 715.34 1812.75 712 1825 710 1852.47 705.52 1924.99 714.21 1950 702 1954.81 699.65 1953.47 \ 695.85 1958 693 1961.32 690.91 1964.9 689.07 1968.61 687.45 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1969.3 689.8 1974.93 684.97 1967.52 685.24 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1982.5 695.6 0 49 13 -strand_filter ", label=strand_filter, lp="1982.5,697.5", pos="e,1976.3,684.42 1788.2,718.53 1799.4,715.34 1812.7,712 1825,710 1852.5,705.52 1925,714.21 1950,702 1954.8,699.65 1953.5,695.85 1958,\ 693 1961.3,690.91 1964.9,689.07 1968.6,687.45"]; filter_gnomADe_maximum_population_allele_frequency -> filter_vcf [_draw_="c 7 -#000000 B 13 4306.85 718.53 4283.94 711.59 4263 698.97 4263 676 4263 676 4263 676 4263 269 4263 204.4 4184.19 250.27 4120 243 \ 4016.67 231.29 3896.28 227.59 3821.34 226.45 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3821.43 224 3814.4 226.35 3821.36 228.9 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 4376 470.6 0 226 50 -filter_gnomADe_maximum_population_allele_frequency ", label=filter_gnomADe_maximum_population_allele_frequency, lp="4376,472.5", pos="e,3812.9,226.33 4306.8,718.53 4283.9,711.59 4263,698.97 4263,676 4263,676 4263,676 4263,269 4263,204.4 4184.2,250.27 4120,243 4016.7,\ 231.29 3896.3,227.59 3821.3,226.45"]; readcount_minimum_base_quality -> tumor_bam_readcount [_draw_="c 7 -#000000 B 25 3517.12 718.51 3500.58 715.46 3481.46 712.24 3464 710 3419.78 704.33 3407.13 713.32 3364 702 3300.53 685.35 3274.84 \ 687.91 3230 640 3208.85 617.4 3229.01 594.53 3205 575 3187.88 561.08 3172.77 581.34 3156 567 3126.83 542.07 3150.42 516.84 3129 \ 485 3101.57 444.23 3076.08 450.18 3028 440 2910.45 415.1 2769.86 408.31 2690.24 406.54 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2690.35 404.09 2683.3 406.39 2690.24 408.99 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3191.5 560.6 0 71 16 -min_base_quality ", label=min_base_quality, lp="3191.5,562.5", pos="e,2681.8,406.36 3517.1,718.51 3500.6,715.46 3481.5,712.24 3464,710 3419.8,704.33 3407.1,713.32 3364,702 3300.5,685.35 3274.8,687.91 \ 3230,640 3208.8,617.4 3229,594.53 3205,575 3187.9,561.08 3172.8,581.34 3156,567 3126.8,542.07 3150.4,516.84 3129,485 3101.6,444.23 \ 3076.1,450.18 3028,440 2910.4,415.1 2769.9,408.31 2690.2,406.54"]; readcount_minimum_base_quality -> normal_bam_readcount [_draw_="c 7 -#000000 B 10 3508.35 718.55 3485.62 711.58 3464 698.93 3464 676 3464 676 3464 676 3464 449 3464 436.03 3298.11 419.56 3204.1 \ 411.28 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3204.49 408.85 3197.3 410.68 3204.06 413.73 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3499.5 560.6 0 71 16 -min_base_quality ", label=min_base_quality, lp="3499.5,562.5", pos="e,3195.8,410.55 3508.3,718.55 3485.6,711.58 3464,698.93 3464,676 3464,676 3464,676 3464,449 3464,436.03 3298.1,419.56 3204.1,411.28"]; mutect_max_alt_allele_in_normal_fraction -> mutect [_draw_="c 7 -#000000 B 7 153.26 718.61 178.37 710.36 218.91 698.28 255 693 360.49 677.58 668.49 675.75 813.63 675.78 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 813.6 678.23 820.6 675.78 813.6 673.33 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 323.5 695.6 0 137 33 -max_alt_allele_in_normal_fraction ", label=max_alt_allele_in_normal_fraction, lp="323.5,697.5", pos="e,822.11,675.78 153.26,718.61 178.37,710.36 218.91,698.28 255,693 360.49,677.58 668.49,675.75 813.63,675.78"]; vep_cache_dir -> annotate_variants [_draw_="c 7 -#000000 B 16 2811.94 718.61 2849.26 704.88 2919 678.84 2919 676 2919 676 2919 676 2919 606.5 2919 591.35 2920.8 585.2 2932 \ 575 2940.94 566.86 2950.82 576.73 2958 567 2980.22 536.91 2960.89 490.45 2948.11 466.48 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2950.38 465.52 2944.83 460.59 2946.09 467.9 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2952 583.1 0 40 9 -cache_dir ", label=cache_dir, lp="2952,585", pos="e,2944.1,459.27 2811.9,718.61 2849.3,704.88 2919,678.84 2919,676 2919,676 2919,676 2919,606.5 2919,591.35 2920.8,585.2 2932,575 \ 2940.9,566.86 2950.8,576.73 2958,567 2980.2,536.91 2960.9,490.45 2948.1,466.48"]; vep_assembly -> annotate_variants [_draw_="c 7 -#000000 B 10 2900.1 718.65 2928.51 706.54 2977 684.61 2977 676 2977 676 2977 676 2977 494 2977 482.09 2968.72 471.93 2959.88 \ 464.48 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2961.4 462.55 2954.35 460.25 2958.42 466.45 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2997 583.1 0 40 8 -assembly ", label=assembly, lp="2997,585", pos="e,2953.1,459.33 2900.1,718.65 2928.5,706.54 2977,684.61 2977,676 2977,676 2977,676 2977,494 2977,482.09 2968.7,471.93 2959.9,464.48"]; variants_to_table_genotype_fields -> variants_to_table [_draw_="c 7 -#000000 B 13 4726.45 718.51 4711.7 710.01 4693 695.41 4693 676 4693 676 4693 676 4693 134 4693 79.91 4504.97 111.6 4451 108 \ 4123.68 86.2 3732.47 83.14 3568.44 82.89 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3568.84 80.44 3561.84 82.88 3568.83 85.34 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 4726 403.1 0 66 15 -genotype_fields ", label=genotype_fields, lp="4726,405", pos="e,3560.3,82.881 4726.4,718.51 4711.7,710.01 4693,695.41 4693,676 4693,676 4693,676 4693,134 4693,79.913 4505,111.6 4451,108 4123.7,\ 86.195 3732.5,83.136 3568.4,82.891"]; pindel_insert_size -> pindel [_draw_="c 7 -#000000 B 7 1097.02 718.59 1093.19 710.91 1089.55 699.77 1096 693 1105.47 683.06 1273.81 678.72 1374.89 677 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1374.78 679.45 1381.73 676.89 1374.69 674.55 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1118 695.6 0 44 11 -insert_size ", label=insert_size, lp="1118,697.5", pos="e,1383.2,676.86 1097,718.59 1093.2,710.91 1089.5,699.77 1096,693 1105.5,683.06 1273.8,678.72 1374.9,677"]; custom_gnomad_vcf -> annotate_variants [_draw_="c 7 -#000000 B 10 2998.61 718.66 3009.78 709.56 3025 693.89 3025 676 3025 676 3025 676 3025 494 3025 478.65 3013.9 468.78 2999.68 \ 462.43 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3000.82 460.24 2993.41 459.97 2999.03 464.81 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3067 583.1 0 84 17 -custom_gnomad_vcf ", label=custom_gnomad_vcf, lp="3067,585", pos="e,2992,459.42 2998.6,718.66 3009.8,709.56 3025,693.89 3025,676 3025,676 3025,676 3025,494 3025,478.65 3013.9,468.78 2999.7,462.43"]; varscan_min_var_freq -> varscan [_draw_="c 7 -#000000 B 10 1917.54 718.56 1928.92 715.59 1942 712.41 1954 710 1965.89 707.62 1998.66 709.74 2008 702 2010.94 699.56 2012.92 \ 696.12 2014.25 692.53 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2016.62 693.15 2015.97 685.77 2011.87 691.95 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2039 695.6 0 52 12 -min_var_freq ", label=min_var_freq, lp="2039,697.5", pos="e,2016.3,684.3 1917.5,718.56 1928.9,715.59 1942,712.41 1954,710 1965.9,707.62 1998.7,709.74 2008,702 2010.9,699.56 2012.9,696.12 \ 2014.3,692.53"]; add_vep_fields_to_table [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 3348.5 0.5 3348.5 19.5 3505.5 19.5 3505.5 0.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3427 7.5 0 141 28 -add VEP annotation to report ", height=0.27778, label="add VEP annotation to report", pos="3427,10", rects="3348.5,0.5,3505.5,19.5", width=2.1806]; vep_to_table_fields -> add_vep_fields_to_table [_draw_="c 7 -#000000 B 10 4891.9 718.56 4887.46 708.62 4881 691.51 4881 676 4881 676 4881 676 4881 81 4881 12.13 3826.58 9.79 3513.58 10.62 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3513.94 8.17 3506.94 10.64 3513.95 13.07 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 4902 380.6 0 42 10 -vep_fields ", label=vep_fields, lp="4902,382.5", pos="e,3505.4,10.64 4891.9,718.56 4887.5,708.62 4881,691.51 4881,676 4881,676 4881,676 4881,81 4881,12.132 3826.6,9.7939 3513.6,10.617"]; tumor_bam_readcount -> tumor_indel_bam_readcount_tsv [_draw_="c 7 -#000000 B 10 2619.8 395.75 2613.38 387.52 2605 374.25 2605 361 2605 361 2605 361 2605 134 2605 121.28 2598.98 108.22 2593.1 \ 98.51 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2595.23 97.29 2589.36 92.77 2591.13 99.97 ", pos="e,2588.5,91.5 2619.8,395.75 2613.4,387.52 2605,374.25 2605,361 2605,361 2605,361 2605,134 2605,121.28 2599,108.22 2593.1,98.506"]; tumor_bam_readcount -> tumor_snv_bam_readcount_tsv [_draw_="c 7 -#000000 B 10 2579 395.52 2546.34 388.34 2509 376.7 2509 361 2509 361 2509 361 2509 134 2509 113.67 2492.79 101.45 2473.16 94.09 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2474.05 91.81 2466.63 91.9 2472.48 96.45 ", pos="e,2465.2,91.415 2579,395.52 2546.3,388.34 2509,376.7 2509,361 2509,361 2509,361 2509,134 2509,113.67 2492.8,101.45 2473.2,94.093"]; add_tumor_bam_readcount_to_vcf [_draw_="c 7 -#000000 C 7 -#f3cea1 P 4 2808 350.5 2808 369.5 3052 369.5 3052 350.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2930 357.5 0 228 46 -Add snv and indel bam-readcount files to a vcf ", fillcolor="#F3CEA1", height=0.27778, label="Add snv and indel bam-readcount files to a vcf", pos="2930,360", rects="2808,350.5,3052,369.5", width=3.3889]; tumor_bam_readcount -> add_tumor_bam_readcount_to_vcf [_draw_="c 7 -#000000 B 10 2681.72 402.22 2727.25 400.14 2788.17 395.8 2811 387 2817.22 384.6 2816.86 380.6 2823 378 2828.85 375.52 2835.01 \ 373.41 2841.31 371.59 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2841.74 374.01 2847.88 369.85 2840.48 369.28 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2875 380.6 0 104 23 -indel_bam_readcount_tsv ", label=indel_bam_readcount_tsv, lp="2875,382.5", pos="e,2849.3,369.46 2681.7,402.22 2727.2,400.14 2788.2,395.8 2811,387 2817.2,384.6 2816.9,380.6 2823,378 2828.8,375.52 2835,373.41 2841.3,\ 371.59"]; tumor_bam_readcount -> add_tumor_bam_readcount_to_vcf [_draw_="c 7 -#000000 B 7 2649.75 395.55 2666.67 389.63 2690.47 382.08 2712 378 2740.21 372.65 2770.78 368.98 2799.86 366.46 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2799.73 368.93 2806.51 365.91 2799.33 364.05 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2761 380.6 0 98 21 -snv_bam_readcount_tsv ", label=snv_bam_readcount_tsv, lp="2761,382.5", pos="e,2808,365.78 2649.7,395.55 2666.7,389.63 2690.5,382.08 2712,378 2740.2,372.65 2770.8,368.98 2799.9,366.46"]; normal_bam_readcount -> normal_indel_bam_readcount_tsv [_draw_="c 7 -#000000 B 16 3107.43 395.5 3101.97 393.26 3096.6 390.46 3092 387 3070.23 370.62 3083.45 351 3063 333 3018.95 294.22 2937 352.19 \ 2937 293.5 2937 293.5 2937 293.5 2937 134 2937 114.26 2919.64 101.88 2900.9 94.28 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2901.95 92.06 2894.54 91.93 2900.25 96.65 ", pos="e,2893.1,91.402 3107.4,395.5 3102,393.26 3096.6,390.46 3092,387 3070.2,370.62 3083.4,351 3063,333 3019,294.22 2937,352.19 2937,293.5 \ 2937,293.5 2937,293.5 2937,134 2937,114.26 2919.6,101.88 2900.9,94.28"]; normal_bam_readcount -> normal_snv_bam_readcount_tsv [_draw_="c 7 -#000000 B 16 3113.54 395.53 3108.7 393.25 3103.95 390.44 3100 387 3093.39 381.25 3093.82 377.89 3090 370 3086.85 363.48 3043 \ 255.74 3043 248.5 3043 248.5 3043 248.5 3043 134 3043 122.42 3041.71 109.43 3040.44 99.46 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3042.9 99.38 3039.52 92.78 3038.04 100.05 ", pos="e,3039.3,91.279 3113.5,395.53 3108.7,393.25 3104,390.44 3100,387 3093.4,381.25 3093.8,377.89 3090,370 3086.8,363.48 3043,255.74 \ 3043,248.5 3043,248.5 3043,248.5 3043,134 3043,122.42 3041.7,109.43 3040.4,99.461"]; add_normal_bam_readcount_to_vcf [_draw_="c 7 -#000000 C 7 -#f3cea1 P 4 3076 305.5 3076 324.5 3320 324.5 3320 305.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3198 312.5 0 228 46 -Add snv and indel bam-readcount files to a vcf ", fillcolor="#F3CEA1", height=0.27778, label="Add snv and indel bam-readcount files to a vcf", pos="3198,315", rects="3076,305.5,3320,324.5", width=3.3889]; normal_bam_readcount -> add_normal_bam_readcount_to_vcf [_draw_="c 7 -#000000 B 7 3124.76 395.56 3107.04 385.21 3082.73 366.97 3095 350 3102.42 339.73 3113.05 332.52 3124.7 327.45 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3125.43 329.8 3131.06 324.98 3123.65 325.23 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3144 358.1 0 98 21 -snv_bam_readcount_tsv ", label=snv_bam_readcount_tsv, lp="3144,360", pos="e,3132.5,324.43 3124.8,395.56 3107,385.21 3082.7,366.97 3095,350 3102.4,339.73 3113.1,332.52 3124.7,327.45"]; normal_bam_readcount -> add_normal_bam_readcount_to_vcf [_draw_="c 7 -#000000 B 7 3159.77 395.71 3170.37 390.02 3182.9 381.44 3190 370 3196.87 358.93 3198.67 344.17 3198.86 332.88 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3201.31 332.84 3198.75 325.89 3196.41 332.93 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3249 358.1 0 104 23 -indel_bam_readcount_tsv ", label=indel_bam_readcount_tsv, lp="3249,360", pos="e,3198.7,324.37 3159.8,395.71 3170.4,390.02 3182.9,381.44 3190,370 3196.9,358.93 3198.7,344.17 3198.9,332.88"]; mutect -> mutect_filtered_vcf [_draw_="c 7 -#000000 B 13 959.98 668.39 1031.83 661.58 1134 648.78 1134 631 1134 631 1134 631 1134 134 1134 95.04 1268.14 109.18 1306 100 \ 1313.61 98.16 1321.71 95.97 1329.39 93.79 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1330.01 96.16 1336.06 91.87 1328.66 91.45 ", pos="e,1337.5,91.447 959.98,668.39 1031.8,661.58 1134,648.78 1134,631 1134,631 1134,631 1134,134 1134,95.038 1268.1,109.18 1306,100 1313.6,\ 98.156 1321.7,95.97 1329.4,93.792"]; mutect -> mutect_unfiltered_vcf [_draw_="c 7 -#000000 B 10 959.94 669.89 1009.64 664.97 1068 654.24 1068 631 1068 631 1068 631 1068 134 1068 110.72 1125.52 97.39 1174.8 \ 90.24 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1174.84 92.71 1181.44 89.31 1174.17 87.86 ", pos="e,1182.9,89.105 959.94,669.89 1009.6,664.97 1068,654.24 1068,631 1068,631 1068,631 1068,134 1068,110.72 1125.5,97.39 1174.8,90.242"]; mutect -> combine [_draw_="c 7 -#000000 B 4 959.78 671.13 1141.74 663.53 1635.46 642.92 1835.3 634.58 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1835.33 637.03 1842.22 634.29 1835.12 632.13 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1520.5 650.6 0 45 10 -mutect_vcf ", label=mutect_vcf, lp="1520.5,652.5", pos="e,1843.7,634.23 959.78,671.13 1141.7,663.53 1635.5,642.92 1835.3,634.58"]; annotated_filter_bgzip [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 3369.5 170.5 3369.5 189.5 3434.5 189.5 3434.5 170.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3402 177.5 0 49 9 -bgzip VCF ", height=0.27778, label="bgzip VCF", pos="3402,180", rects="3369.5,170.5,3434.5,189.5", width=0.90278]; filter_vcf -> annotated_filter_bgzip [_draw_="c 7 -#000000 B 4 3685.35 216.11 3614.68 207.35 3502.68 193.48 3442.85 186.06 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3443.17 183.63 3435.92 185.2 3442.56 188.5 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3612.5 200.6 0 13 4 -file ", label=file, lp="3612.5,202.5", pos="e,3434.4,185.02 3685.4,216.11 3614.7,207.35 3502.7,193.48 3442.9,186.06"]; index [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 3167 260.5 3167 279.5 3229 279.5 3229 260.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3198 267.5 0 46 9 -vcf index ", height=0.27778, label="vcf index", pos="3198,270", rects="3167,260.5,3229,279.5", width=0.86111]; index -> final_vcf [_draw_="c 7 -#000000 B 10 3191.45 260.64 3185.62 252.34 3178 239.01 3178 226 3178 226 3178 226 3178 134 3178 121.6 3173.01 108.51 3168.14 \ 98.69 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3170.37 97.66 3164.91 92.64 3166.04 99.97 ", pos="e,3164.2,91.309 3191.5,260.64 3185.6,252.34 3178,239.01 3178,226 3178,226 3178,226 3178,134 3178,121.6 3173,108.51 3168.1,98.694"]; index -> filter_vcf [_draw_="c 7 -#000000 B 4 3228.8 266.6 3314.21 259.93 3555.7 241.09 3677.24 231.6 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3677.13 234.07 3683.92 231.08 3676.75 229.18 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3528.5 245.6 0 13 3 -vcf ", label=vcf, lp="3528.5,247.5", pos="e,3685.4,230.96 3228.8,266.6 3314.2,259.93 3555.7,241.09 3677.2,231.6"]; varscan -> varscan_unfiltered_vcf [_draw_="c 7 -#000000 B 10 2053.64 665.6 2070.58 659.33 2087 648.69 2087 631 2087 631 2087 631 2087 134 2087 116.81 2101.57 103.97 2115.98 \ 95.47 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2117.11 97.64 2122.09 92.14 2114.77 93.34 ", pos="e,2123.4,91.419 2053.6,665.6 2070.6,659.33 2087,648.69 2087,631 2087,631 2087,631 2087,134 2087,116.81 2101.6,103.97 2116,95.468"]; varscan -> varscan_filtered_vcf [_draw_="c 7 -#000000 B 10 2017.31 665.76 2017.6 657.1 2018 643.1 2018 631 2018 631 2018 631 2018 134 2018 122.59 2018.25 109.75 2018.5 99.81 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2020.95 99.88 2018.7 92.82 2016.06 99.75 ", pos="e,2018.7,91.303 2017.3,665.76 2017.6,657.1 2018,643.1 2018,631 2018,631 2018,631 2018,134 2018,122.59 2018.3,109.75 2018.5,99.806"]; varscan -> combine [_draw_="c 7 -#000000 B 7 1987.42 665.56 1979.98 663.11 1972.1 660.21 1965 657 1956.63 653.21 1947.84 648.24 1940.33 643.66 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1941.83 641.71 1934.6 640.07 1939.23 645.86 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1989.5 650.6 0 49 11 -varscan_vcf ", label=varscan_vcf, lp="1989.5,652.5", pos="e,1933.3,639.26 1987.4,665.56 1980,663.11 1972.1,660.21 1965,657 1956.6,653.21 1947.8,648.24 1940.3,643.66"]; docm -> docm_filtered_vcf [_draw_="c 7 -#000000 B 10 2414.36 665.53 2413.48 653.05 2412 628.99 2412 608.5 2412 608.5 2412 608.5 2412 134 2412 131.01 2342.01 108.01 \ 2298.29 93.94 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2299.31 91.7 2291.9 91.89 2297.82 96.36 ", pos="e,2290.5,91.426 2414.4,665.53 2413.5,653.05 2412,628.99 2412,608.5 2412,608.5 2412,608.5 2412,134 2412,131.01 2342,108.01 2298.3,\ 93.942"]; docm -> add_docm_variants [_draw_="c 7 -#000000 B 10 2469.6 665.55 2504.02 658.63 2542 647.29 2542 631 2542 631 2542 631 2542 539 2542 530.31 2542 520.63 2542 512.65 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2544.45 512.76 2542 505.76 2539.55 512.76 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2561.5 583.1 0 39 8 -docm_vcf ", label=docm_vcf, lp="2561.5,585", pos="e,2542,504.24 2469.6,665.55 2504,658.63 2542,647.29 2542,631 2542,631 2542,631 2542,539 2542,530.31 2542,520.63 2542,512.65"]; decompose_index [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 2457 530.5 2457 549.5 2519 549.5 2519 530.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2488 537.5 0 46 9 -vcf index ", height=0.27778, label="vcf index", pos="2488,540", rects="2457,530.5,2519,549.5", width=0.86111]; decompose_index -> add_docm_variants [_draw_="c 7 -#000000 B 7 2488.28 530.79 2488.89 525.14 2490.57 517.82 2495 513 2496.44 511.43 2498.03 510.01 2499.74 508.72 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2500.83 510.93 2505.5 505.16 2498.26 506.76 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2516.5 515.6 0 43 11 -callers_vcf ", label=callers_vcf, lp="2516.5,517.5", pos="e,2506.8,504.37 2488.3,530.79 2488.9,525.14 2490.6,517.82 2495,513 2496.4,511.43 2498,510.01 2499.7,508.72"]; pindel -> pindel_filtered_vcf [_draw_="c 7 -#000000 B 10 1452.85 665.54 1455.48 656.95 1459 643.2 1459 631 1459 631 1459 631 1459 134 1459 121.6 1463.99 108.51 1468.86 \ 98.69 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1470.96 99.97 1472.09 92.64 1466.63 97.66 ", pos="e,1472.8,91.309 1452.8,665.54 1455.5,656.95 1459,643.2 1459,631 1459,631 1459,631 1459,134 1459,121.6 1464,108.51 1468.9,98.694"]; pindel -> pindel_unfiltered_vcf [_draw_="c 7 -#000000 B 10 1498.65 665.58 1516.3 659.48 1532 649 1532 631 1532 631 1532 631 1532 134 1532 116.1 1547.55 103.4 1563.2 95.15 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1564.23 97.37 1569.46 92.11 1562.09 92.96 ", pos="e,1570.8,91.452 1498.6,665.58 1516.3,659.48 1532,649 1532,631 1532,631 1532,631 1532,134 1532,116.1 1547.6,103.4 1563.2,95.148"]; pindel -> combine [_draw_="c 7 -#000000 B 10 1516.83 671.21 1621.66 666.8 1813.68 658.56 1821 657 1831.74 654.72 1833.5 651.19 1844 648 1851.96 645.58 1860.47 \ 643.35 1868.84 641.36 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1869.38 643.75 1875.65 639.79 1868.27 638.98 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1865 650.6 0 42 10 -pindel_vcf ", label=pindel_vcf, lp="1865,652.5", pos="e,1877.1,639.45 1516.8,671.21 1621.7,666.8 1813.7,658.56 1821,657 1831.7,654.72 1833.5,651.19 1844,648 1852,645.58 1860.5,643.35 \ 1868.8,641.36"]; decompose [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 2430 575.5 2430 594.5 2534 594.5 2534 575.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2482 582.5 0 88 16 -run vt decompose ", height=0.27778, label="run vt decompose", pos="2482,585", rects="2430,575.5,2534,594.5", width=1.4444]; decompose -> decompose_index [_draw_="c 7 -#000000 B 4 2483.16 575.71 2483.87 570.59 2484.81 563.85 2485.67 557.67 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2488.1 558.04 2486.64 550.76 2483.24 557.36 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2491.5 560.6 0 13 3 -vcf ", label=vcf, lp="2491.5,562.5", pos="e,2486.8,549.27 2483.2,575.71 2483.9,570.59 2484.8,563.85 2485.7,557.67"]; add_normal_bam_readcount_to_vcf -> index [_draw_="c 7 -#000000 B 4 3198 305.71 3198 300.59 3198 293.85 3198 287.67 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3200.45 287.78 3198 280.78 3195.55 287.78 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3204.5 290.6 0 13 3 -vcf ", label=vcf, lp="3204.5,292.5", pos="e,3198,279.27 3198,305.71 3198,300.59 3198,293.85 3198,287.67"]; annotate_variants -> vep_summary [_draw_="c 7 -#000000 B 10 2898.83 440.55 2828.16 425.4 2689 394.21 2689 383.5 2689 383.5 2689 383.5 2689 134 2689 120.64 2696.48 107.47 \ 2703.7 97.86 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2705.59 99.42 2708.1 92.44 2701.79 96.33 ", pos="e,2709.1,91.261 2898.8,440.55 2828.2,425.4 2689,394.21 2689,383.5 2689,383.5 2689,383.5 2689,134 2689,120.64 2696.5,107.47 2703.7,\ 97.859"]; annotate_variants -> tumor_bam_readcount [_draw_="c 7 -#000000 B 4 2873.43 440.51 2824.42 434.1 2755.54 424.92 2690.3 415.61 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2690.73 413.2 2683.45 414.63 2690.04 418.05 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2809.5 425.6 0 13 3 -vcf ", label=vcf, lp="2809.5,427.5", pos="e,2682,414.42 2873.4,440.51 2824.4,434.1 2755.5,424.92 2690.3,415.61"]; annotate_variants -> normal_bam_readcount [_draw_="c 7 -#000000 B 4 2978.91 440.5 3011.69 433.53 3058.24 423.62 3093.04 416.21 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3093.36 418.65 3099.69 414.79 3092.34 413.85 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3064.5 425.6 0 13 3 -vcf ", label=vcf, lp="3064.5,427.5", pos="e,3101.2,414.48 2978.9,440.5 3011.7,433.53 3058.2,423.62 3093,416.21"]; annotate_variants -> add_tumor_bam_readcount_to_vcf [_draw_="c 7 -#000000 B 10 2933.83 440.71 2929.99 434.05 2925.08 424.3 2923 415 2921.06 406.33 2922.1 403.84 2923 395 2923.59 389.18 2924.74 \ 382.88 2925.94 377.3 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2928.26 378.16 2927.45 370.78 2923.49 377.05 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2929.5 403.1 0 13 3 -vcf ", label=vcf, lp="2929.5,405", pos="e,2927.8,369.31 2933.8,440.71 2930,434.05 2925.1,424.3 2923,415 2921.1,406.33 2922.1,403.84 2923,395 2923.6,389.18 2924.7,382.88 \ 2925.9,377.3"]; add_docm_variants -> annotate_variants [_draw_="c 7 -#000000 B 10 2619.32 491.41 2681.46 488.85 2763.54 484.25 2796 477 2806.71 474.61 2808.38 470.79 2819 468 2829.64 465.2 2840.95 \ 462.84 2852.2 460.85 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2852.39 463.3 2858.88 459.72 2851.57 458.47 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2825.5 470.6 0 13 3 -vcf ", label=vcf, lp="2825.5,472.5", pos="e,2860.4,459.47 2619.3,491.41 2681.5,488.85 2763.5,484.25 2796,477 2806.7,474.61 2808.4,470.79 2819,468 2829.6,465.2 2840.9,462.84 \ 2852.2,460.85"]; add_tumor_bam_readcount_to_vcf -> add_normal_bam_readcount_to_vcf [_draw_="c 7 -#000000 B 7 2974.67 350.51 3003.3 345.19 3041.28 338.35 3075 333 3091.19 330.43 3108.62 327.89 3125.12 325.58 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3125.04 328.07 3131.64 324.68 3124.37 323.21 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3081.5 335.6 0 13 3 -vcf ", label=vcf, lp="3081.5,337.5", pos="e,3133.1,324.47 2974.7,350.51 3003.3,345.19 3041.3,338.35 3075,333 3091.2,330.43 3108.6,327.89 3125.1,325.58"]; strelka -> strelka_filtered_vcf [_draw_="c 7 -#000000 B 10 1735.73 665.65 1747.3 658.25 1761 646.27 1761 631 1761 631 1761 631 1761 134 1761 128.39 1825.02 107.18 1866.78 \ 93.95 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1867.43 96.31 1873.37 91.87 1865.96 91.64 ", pos="e,1874.8,91.413 1735.7,665.65 1747.3,658.25 1761,646.27 1761,631 1761,631 1761,631 1761,134 1761,128.39 1825,107.18 1866.8,93.946"]; strelka -> strelka_unfiltered_vcf [_draw_="c 7 -#000000 B 10 1720 665.76 1720 657.1 1720 643.09 1720 631 1720 631 1720 631 1720 134 1720 122.59 1720 109.75 1720 99.81 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1722.45 99.82 1720 92.82 1717.55 99.82 ", pos="e,1720,91.304 1720,665.76 1720,657.1 1720,643.09 1720,631 1720,631 1720,631 1720,134 1720,122.59 1720,109.75 1720,99.808"]; strelka -> combine [_draw_="c 7 -#000000 B 7 1768.47 671.99 1809.94 669.74 1866.14 665.26 1887 657 1894.15 654.17 1901.08 649.38 1906.79 644.67 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1908.11 646.77 1911.75 640.31 1904.87 643.1 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1924 650.6 0 44 11 -strelka_vcf ", label=strelka_vcf, lp="1924,652.5", pos="e,1912.9,639.31 1768.5,671.99 1809.9,669.74 1866.1,665.26 1887,657 1894.2,654.17 1901.1,649.38 1906.8,644.67"]; annotated_filter_index [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 3371 125.5 3371 144.5 3433 144.5 3433 125.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3402 132.5 0 46 9 -vcf index ", height=0.27778, label="vcf index", pos="3402,135", rects="3371,125.5,3433,144.5", width=0.86111]; annotated_filter_index -> final_filtered_vcf [_draw_="c 7 -#000000 B 4 3375.41 125.58 3348.15 116.94 3305.61 103.47 3275.7 93.99 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3276.48 91.67 3269.07 91.89 3275 96.34 ", pos="e,3267.6,91.434 3375.4,125.58 3348.1,116.94 3305.6,103.47 3275.7,93.992"]; annotated_filter_index -> add_vep_fields_to_table [_draw_="c 7 -#000000 B 7 3400.86 125.9 3398.93 109.97 3396.02 73.62 3405 45 3407.13 38.21 3411.02 31.47 3414.94 25.81 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3416.68 27.57 3418.89 20.5 3412.74 24.65 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3411.5 80.1 0 13 3 -vcf ", label=vcf, lp="3411.5,82", pos="e,3419.8,19.282 3400.9,125.9 3398.9,109.97 3396,73.617 3405,45 3407.1,38.208 3411,31.47 3414.9,25.806"]; annotated_filter_index -> variants_to_table [_draw_="c 7 -#000000 B 7 3407.62 125.79 3411.84 120.14 3418.07 112.81 3425 108 3432.99 102.45 3442.37 97.92 3451.49 94.32 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3452.26 96.65 3457.97 91.92 3450.56 92.05 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3431.5 110.6 0 13 3 -vcf ", label=vcf, lp="3431.5,112.5", pos="e,3459.4,91.39 3407.6,125.79 3411.8,120.14 3418.1,112.81 3425,108 3433,102.45 3442.4,97.925 3451.5,94.321"]; combine -> decompose [_draw_="c 7 -#000000 B 4 1998.42 623.07 2111.41 614.41 2319.18 598.48 2421.63 590.63 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2421.72 593.08 2428.51 590.1 2421.34 588.19 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2257.5 605.6 0 13 3 -vcf ", label=vcf, lp="2257.5,607.5", pos="e,2430,589.98 1998.4,623.07 2111.4,614.41 2319.2,598.48 2421.6,590.63"]; annotated_filter_bgzip -> annotated_filter_index [_draw_="c 7 -#000000 B 4 3402 170.71 3402 165.59 3402 158.85 3402 152.67 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3404.45 152.78 3402 145.78 3399.55 152.78 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3408.5 155.6 0 13 3 -vcf ", label=vcf, lp="3408.5,157.5", pos="e,3402,144.27 3402,170.71 3402,165.59 3402,158.85 3402,152.67"]; add_vep_fields_to_table -> final_tsv [_draw_="c 7 -#000000 B 7 3348.51 10.98 3038.92 11.12 1915.91 13.8 1847 45 1837.3 49.39 1829.18 58.14 1823.42 65.91 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1821.61 64.21 1819.67 71.37 1825.65 66.98 ", pos="e,1818.8,72.616 3348.5,10.98 3038.9,11.123 1915.9,13.798 1847,45 1837.3,49.391 1829.2,58.135 1823.4,65.906"]; variants_to_table -> add_vep_fields_to_table [_draw_="c 7 -#000000 B 4 3482.53 72.7 3472.01 61.01 3452.7 39.56 3439.86 25.29 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3441.98 23.98 3435.48 20.42 3438.34 27.26 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3455.5 30.6 0 13 3 -tsv ", label=tsv, lp="3455.5,32.5", pos="e,3434.5,19.294 3482.5,72.695 3472,61.012 3452.7,39.559 3439.9,25.286"]; default1 [_draw_="c 7 -#000000 C 7 -#d5aefc P 4 2419 440.5 2419 459.5 2481 459.5 2481 440.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2450 447.5 0 46 7 -\"TUMOR\" ", fillcolor="#D5AEFC", height=0.27778, label="\"TUMOR\"", pos="2450,450", rects="2419,440.5,2481,459.5", width=0.86111]; default1 -> tumor_bam_readcount [_draw_="c 7 -#000000 B 7 2448.49 440.57 2447.99 434.82 2448.46 427.46 2453 423 2460.99 415.15 2517.63 410.7 2564.16 408.34 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2564.03 410.8 2570.9 408.01 2563.79 405.9 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2468.5 425.6 0 31 6 -sample ", label=sample, lp="2468.5,427.5", pos="e,2572.4,407.94 2448.5,440.57 2448,434.82 2448.5,427.46 2453,423 2461,415.15 2517.6,410.7 2564.2,408.34"]; default2 [_draw_="c 7 -#000000 C 7 -#d5aefc P 4 3158 440.5 3158 459.5 3226 459.5 3226 440.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3192 447.5 0 52 8 -\"NORMAL\" ", fillcolor="#D5AEFC", height=0.27778, label="\"NORMAL\"", pos="3192,450", rects="3158,440.5,3226,459.5", width=0.94444]; default2 -> normal_bam_readcount [_draw_="c 7 -#000000 B 4 3182.17 440.71 3175.11 434.76 3165.44 426.61 3157.25 419.7 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3158.89 417.88 3151.96 415.24 3155.73 421.63 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3186.5 425.6 0 31 6 -sample ", label=sample, lp="3186.5,427.5", pos="e,3150.8,414.27 3182.2,440.71 3175.1,434.76 3165.4,426.61 3157.2,419.7"]; default3 [_draw_="c 7 -#000000 C 7 -#d5aefc P 4 3660 260.5 3660 279.5 3768 279.5 3768 260.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3714 267.5 0 92 14 -\"NORMAL,TUMOR\" ", fillcolor="#D5AEFC", height=0.27778, label="\"NORMAL,TUMOR\"", pos="3714,270", rects="3660,260.5,3768,279.5", width=1.5]; default3 -> filter_vcf [_draw_="c 7 -#000000 B 7 3713.46 260.57 3713.53 255.11 3714.44 248.09 3718 243 3718.92 241.68 3719.98 240.45 3721.14 239.31 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3722.37 241.46 3726.39 235.24 3719.36 237.59 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3749 245.6 0 62 12 -sample_names ", label=sample_names, lp="3749,247.5", pos="e,3727.6,234.31 3713.5,260.57 3713.5,255.11 3714.4,248.09 3718,243 3718.9,241.68 3720,240.45 3721.1,239.31"]; default4 [_draw_="c 7 -#000000 C 7 -#d5aefc P 4 3358 350.5 3358 369.5 3426 369.5 3426 350.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3392 357.5 0 52 8 -\"NORMAL\" ", fillcolor="#D5AEFC", height=0.27778, label="\"NORMAL\"", pos="3392,360", rects="3358,350.5,3426,369.5", width=0.94444]; default4 -> add_normal_bam_readcount_to_vcf [_draw_="c 7 -#000000 B 7 3371.88 350.59 3357.41 344.85 3337.29 337.49 3319 333 3307.62 330.2 3295.51 327.82 3283.53 325.81 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3284.05 323.41 3276.75 324.71 3283.27 328.25 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3376 335.6 0 58 11 -sample_name ", label=sample_name, lp="3376,337.5", pos="e,3275.3,324.47 3371.9,350.59 3357.4,344.85 3337.3,337.49 3319,333 3307.6,330.2 3295.5,327.82 3283.5,325.81"]; default5 [_draw_="c 7 -#000000 C 7 -#d5aefc P 4 3306.5 350.5 3306.5 369.5 3353.5 369.5 3353.5 350.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3330 357.5 0 31 5 -\"DNA\" ", fillcolor="#D5AEFC", height=0.27778, label="\"DNA\"", pos="3330,360", rects="3306.5,350.5,3353.5,369.5", width=0.65278]; default5 -> add_normal_bam_readcount_to_vcf [_draw_="c 7 -#000000 B 7 3306.73 351.23 3305.47 350.81 3304.22 350.4 3303 350 3279.38 342.24 3252.72 333.61 3232.18 326.99 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3233.2 324.74 3225.78 324.93 3231.69 329.4 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3297.5 335.6 0 41 9 -data_type ", label=data_type, lp="3297.5,337.5", pos="e,3224.3,324.46 3306.7,351.23 3305.5,350.81 3304.2,350.4 3303,350 3279.4,342.24 3252.7,333.61 3232.2,326.99"]; default6 [_draw_="c 7 -#000000 C 7 -#d5aefc P 4 3004.5 395.5 3004.5 414.5 3051.5 414.5 3051.5 395.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3028 402.5 0 31 5 -\"DNA\" ", fillcolor="#D5AEFC", height=0.27778, label="\"DNA\"", pos="3028,405", rects="3004.5,395.5,3051.5,414.5", width=0.65278]; default6 -> add_tumor_bam_readcount_to_vcf [_draw_="c 7 -#000000 B 7 3021.63 395.5 3016.85 389.72 3009.81 382.35 3002 378 2998 375.77 2993.73 373.83 2989.32 372.15 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2990.14 369.84 2982.72 369.88 2988.54 374.47 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3033.5 380.6 0 41 9 -data_type ", label=data_type, lp="3033.5,382.5", pos="e,2981.3,369.38 3021.6,395.5 3016.8,389.72 3009.8,382.35 3002,378 2998,375.77 2993.7,373.83 2989.3,372.15"]; default7 [_draw_="c 7 -#000000 C 7 -#d5aefc P 4 2938 395.5 2938 414.5 3000 414.5 3000 395.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2969 402.5 0 46 7 -\"TUMOR\" ", fillcolor="#D5AEFC", height=0.27778, label="\"TUMOR\"", pos="2969,405", rects="2938,395.5,3000,414.5", width=0.86111]; default7 -> add_tumor_bam_readcount_to_vcf [_draw_="c 7 -#000000 B 7 2956.74 395.68 2953.38 393.1 2949.88 390.12 2947 387 2944.04 383.8 2941.26 380.03 2938.84 376.37 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2940.98 375.19 2935.22 370.52 2936.81 377.76 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2976 380.6 0 58 11 -sample_name ", label=sample_name, lp="2976,382.5", pos="e,2934.4,369.23 2956.7,395.68 2953.4,393.1 2949.9,390.12 2947,387 2944,383.8 2941.3,380.03 2938.8,376.37"]; }