digraph workflow { graph [_draw_="c 9 -#fffffe00 C 7 -#eeeeee P 4 0 0 0 683 4283 683 4283 0 ", bb="0,0,4283,683", bgcolor="#eeeeee", clusterrank=local, color=black, dpi=96, fontsize=10, labeljust=left, nodesep=0.05, ranksep=0.22, xdotversion=1.7 ]; node [color=black, fillcolor=lightgoldenrodyellow, fontcolor=black, fontname=Helvetica, fontsize=10, height=0, label="\N", shape=record, style=filled, width=0 ]; edge [arrowsize=0.7, color=black, fontcolor=black, fontname=Helvetica, fontsize=8 ]; subgraph cluster_outputs { graph [_draw_="S 6 -dashed c 7 -#000000 C 7 -#eeeeee P 4 848 45 848 100 3092 100 3092 45 ", _ldraw_="F 10 11 -Times-Roman c 7 -#000000 T 902 52 0 92 16 -Workflow Outputs ", bb="848,45,3092,100", label="Workflow Outputs", labelloc=b, lheight=0.15, lp="902,54.5", lwidth=1.28, rank=same, style=dashed ]; pindel_unfiltered_vcf [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 1209.5 72.5 1209.5 91.5 1328.5 91.5 1328.5 72.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1269 79.5 0 103 21 -pindel_unfiltered_vcf ", fillcolor="#94DDF4", height=0.27778, label=pindel_unfiltered_vcf, pos="1269,82", rects="1209.5,72.5,1328.5,91.5", width=1.6528]; 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varscan_min_coverage [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 1842.5 628.5 1842.5 647.5 1971.5 647.5 1971.5 628.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1907 635.5 0 113 20 -varscan_min_coverage ", fillcolor="#94DDF4", height=0.27778, label=varscan_min_coverage, pos="1907,638", rects="1842.5,628.5,1971.5,647.5", width=1.7917]; vep_to_table_fields [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 2357.5 628.5 2357.5 647.5 2468.5 647.5 2468.5 628.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2413 635.5 0 95 19 -vep_to_table_fields ", fillcolor="#94DDF4", height=0.27778, label=vep_to_table_fields, pos="2413,638", rects="2357.5,628.5,2468.5,647.5", width=1.5417]; tumor_cram [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 1390 628.5 1390 647.5 1466 647.5 1466 628.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1428 635.5 0 60 10 -tumor_cram ", fillcolor="#94DDF4", height=0.27778, label=tumor_cram, pos="1428,638", rects="1390,628.5,1466,647.5", width=1.0556]; readcount_minimum_base_quality [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 2817.5 628.5 2817.5 647.5 3002.5 647.5 3002.5 628.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2910 635.5 0 169 30 -readcount_minimum_base_quality ", fillcolor="#94DDF4", height=0.27778, label=readcount_minimum_base_quality, pos="2910,638", rects="2817.5,628.5,3002.5,647.5", width=2.5694]; cosmic_vcf [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 668.5 628.5 668.5 647.5 739.5 647.5 739.5 628.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 704 635.5 0 55 10 -cosmic_vcf ", fillcolor="#94DDF4", height=0.27778, label=cosmic_vcf, pos="704,638", rects="668.5,628.5,739.5,647.5", width=0.98611]; varscan_min_var_freq [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 1975.5 628.5 1975.5 647.5 2100.5 647.5 2100.5 628.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2038 635.5 0 109 20 -varscan_min_var_freq ", fillcolor="#94DDF4", height=0.27778, label=varscan_min_var_freq, pos="2038,638", rects="1975.5,628.5,2100.5,647.5", width=1.7361]; strelka_exome_mode [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 1594.5 628.5 1594.5 647.5 1715.5 647.5 1715.5 628.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1655 635.5 0 105 18 -strelka_exome_mode ", fillcolor="#94DDF4", height=0.27778, label=strelka_exome_mode, pos="1655,638", rects="1594.5,628.5,1715.5,647.5", width=1.6806]; normal_cram [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 1304.5 628.5 1304.5 647.5 1385.5 647.5 1385.5 628.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1345 635.5 0 65 11 -normal_cram ", fillcolor="#94DDF4", height=0.27778, label=normal_cram, pos="1345,638", rects="1304.5,628.5,1385.5,647.5", width=1.125]; filter_mapq0_threshold [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 3434.5 628.5 3434.5 647.5 3563.5 647.5 3563.5 628.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3499 635.5 0 113 22 -filter_mapq0_threshold ", fillcolor="#94DDF4", height=0.27778, label=filter_mapq0_threshold, pos="3499,638", rects="3434.5,628.5,3563.5,647.5", width=1.7917]; mutect_scatter_count [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 744 628.5 744 647.5 866 647.5 866 628.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 805 635.5 0 106 20 -mutect_scatter_count ", fillcolor="#94DDF4", height=0.27778, label=mutect_scatter_count, pos="805,638", rects="744,628.5,866,647.5", width=1.6944]; strelka_cpu_reserved [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 1470 628.5 1470 647.5 1590 647.5 1590 628.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1530 635.5 0 104 20 -strelka_cpu_reserved ", fillcolor="#94DDF4", height=0.27778, label=strelka_cpu_reserved, pos="1530,638", rects="1470,628.5,1590,647.5", width=1.6667]; docm_vcf [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 1158 628.5 1158 647.5 1222 647.5 1222 628.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1190 635.5 0 48 8 -docm_vcf ", fillcolor="#94DDF4", height=0.27778, label=docm_vcf, pos="1190,638", rects="1158,628.5,1222,647.5", width=0.88889]; 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mutect_artifact_detection_mode [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 870 628.5 870 647.5 1046 647.5 1046 628.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 958 635.5 0 160 30 -mutect_artifact_detection_mode ", fillcolor="#94DDF4", height=0.27778, label=mutect_artifact_detection_mode, pos="958,638", rects="870,628.5,1046,647.5", width=2.4444]; panel_of_normals_vcf [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 16 628.5 16 647.5 140 647.5 140 628.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 78 635.5 0 108 20 -panel_of_normals_vcf ", fillcolor="#94DDF4", height=0.27778, label=panel_of_normals_vcf, pos="78,638", rects="16,628.5,140,647.5", width=1.7222]; mutect_max_alt_alleles_in_normal_count [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 144 628.5 144 647.5 364 647.5 364 628.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 254 635.5 0 204 38 -mutect_max_alt_alleles_in_normal_count ", fillcolor="#94DDF4", height=0.27778, label=mutect_max_alt_alleles_in_normal_count, pos="254,638", rects="144,628.5,364,647.5", width=3.0556]; varscan_p_value [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 2255 628.5 2255 647.5 2353 647.5 2353 628.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2304 635.5 0 82 15 -varscan_p_value ", fillcolor="#94DDF4", height=0.27778, label=varscan_p_value, pos="2304,638", rects="2255,628.5,2353,647.5", width=1.3611]; mutect_max_alt_allele_in_normal_fraction [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 368.5 628.5 368.5 647.5 593.5 647.5 593.5 628.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 481 635.5 0 209 40 -mutect_max_alt_allele_in_normal_fraction ", fillcolor="#94DDF4", height=0.27778, label=mutect_max_alt_allele_in_normal_fraction, pos="481,638", rects="368.5,628.5,593.5,647.5", width=3.125]; vep_pick [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 2753 628.5 2753 647.5 2813 647.5 2813 628.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2783 635.5 0 44 8 -vep_pick ", fillcolor="#94DDF4", height=0.27778, label=vep_pick, pos="2783,638", rects="2753,628.5,2813,647.5", width=0.83333]; variants_to_table_genotype_fields [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 4083 628.5 4083 647.5 4267 647.5 4267 628.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 4175 635.5 0 168 33 -variants_to_table_genotype_fields ", fillcolor="#94DDF4", height=0.27778, label=variants_to_table_genotype_fields, pos="4175,638", rects="4083,628.5,4267,647.5", width=2.5556]; variants_to_table_fields [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 3945.5 628.5 3945.5 647.5 4078.5 647.5 4078.5 628.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 4012 635.5 0 117 24 -variants_to_table_fields ", fillcolor="#94DDF4", height=0.27778, label=variants_to_table_fields, pos="4012,638", rects="3945.5,628.5,4078.5,647.5", width=1.8472]; vep_cache_dir [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 3135 628.5 3135 647.5 3221 647.5 3221 628.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3178 635.5 0 70 13 -vep_cache_dir ", fillcolor="#94DDF4", height=0.27778, label=vep_cache_dir, pos="3178,638", rects="3135,628.5,3221,647.5", width=1.1944]; } pindel [_draw_="c 7 -#000000 C 7 -#f3cea1 P 4 1163 575.5 1163 594.5 1297 594.5 1297 575.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1230 582.5 0 118 24 -pindel parallel workflow ", fillcolor="#F3CEA1", height=0.27778, label="pindel parallel workflow", pos="1230,585", rects="1163,575.5,1297,594.5", width=1.8611]; pindel_insert_size -> pindel [_draw_="c 7 -#000000 B 13 1076.84 628.51 1067.27 625.51 1056.21 622.31 1046 620 1034.38 617.37 1000.77 621.03 993 612 990.39 608.97 990.27 \ 605.93 993 603 1003.97 591.22 1089.65 587.48 1154.87 586.36 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1154.65 588.82 1161.61 586.26 1154.57 583.92 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1015 605.6 0 44 11 -insert_size ", label=insert_size, lp="1015,607.5", pos="e,1163.1,586.23 1076.8,628.51 1067.3,625.51 1056.2,622.31 1046,620 1034.4,617.37 1000.8,621.03 993,612 990.39,608.97 990.27,605.93 \ 993,603 1004,591.22 1089.7,587.48 1154.9,586.36"]; mutect [_draw_="c 7 -#000000 C 7 -#f3cea1 P 4 635 575.5 635 594.5 773 594.5 773 575.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 704 582.5 0 122 24 -mutect parallel workflow ", fillcolor="#F3CEA1", height=0.27778, label="mutect parallel workflow", pos="704,585", rects="635,575.5,773,594.5", width=1.9167]; dbsnp_vcf -> mutect [_draw_="c 7 -#000000 B 13 615.97 628.62 609.42 625.36 601.53 621.95 594 620 582.67 617.07 496.95 620.58 489 612 486.28 609.07 486.29 605.94 \ 489 603 498.42 592.81 568.99 588.72 626.76 587.08 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 626.73 589.54 633.66 586.9 626.6 584.64 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 510 605.6 0 42 9 -dbsnp_vcf ", label=dbsnp_vcf, lp="510,607.5", pos="e,635.18,586.86 615.97,628.62 609.42,625.36 601.53,621.95 594,620 582.67,617.07 496.95,620.58 489,612 486.28,609.07 486.29,605.94 \ 489,603 498.42,592.81 568.99,588.72 626.76,587.08"]; interval_list -> mutect [_draw_="c 7 -#000000 B 13 1246.7 628.58 1239.35 625.23 1230.45 621.76 1222 620 1172.06 609.6 811.25 628.55 763 612 756.69 609.84 756.87 \ 606.17 751 603 747.28 600.99 743.27 599.13 739.22 597.43 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 740.26 595.21 732.85 594.93 738.47 599.77 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 786.5 605.6 0 47 13 -interval_list ", label=interval_list, lp="786.5,607.5", pos="e,731.44,594.38 1246.7,628.58 1239.4,625.23 1230.4,621.76 1222,620 1172.1,609.6 811.25,628.55 763,612 756.69,609.84 756.87,606.17 \ 751,603 747.28,600.99 743.27,599.13 739.22,597.43"]; docm [_draw_="c 7 -#000000 C 7 -#f3cea1 P 4 1351.5 575.5 1351.5 594.5 1474.5 594.5 1474.5 575.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1413 582.5 0 107 20 -Detect Docm variants ", fillcolor="#F3CEA1", height=0.27778, label="Detect Docm variants", pos="1413,585", rects="1351.5,575.5,1474.5,594.5", width=1.7083]; interval_list -> docm [_draw_="c 7 -#000000 B 10 1242.71 628.55 1227.13 621.97 1208.09 613.67 1207 612 1204.82 608.64 1204.29 605.94 1207 603 1207.59 602.36 1283.88 \ 596.19 1343.43 591.47 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1343.42 593.93 1350.21 590.93 1343.04 589.04 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1230.5 605.6 0 47 13 -interval_list ", label=interval_list, lp="1230.5,607.5", pos="e,1351.7,590.81 1242.7,628.55 1227.1,621.97 1208.1,613.67 1207,612 1204.8,608.64 1204.3,605.94 1207,603 1207.6,602.36 1283.9,596.19 \ 1343.4,591.47"]; strelka [_draw_="c 7 -#000000 C 7 -#f3cea1 P 4 1601.5 575.5 1601.5 594.5 1698.5 594.5 1698.5 575.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1650 582.5 0 81 16 -strelka workflow ", fillcolor="#F3CEA1", height=0.27778, label="strelka workflow", pos="1650,585", rects="1601.5,575.5,1698.5,594.5", width=1.3472]; interval_list -> strelka [_draw_="c 7 -#000000 B 13 1281.82 628.63 1290.52 624.3 1300.74 618.56 1309 612 1313.19 608.67 1312.17 605.31 1317 603 1333.05 595.3 1459.22 \ 595.91 1477 595 1515.77 593.02 1559.41 590.75 1593.17 588.99 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1593.16 591.44 1600.02 588.63 1592.9 586.55 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1340.5 605.6 0 47 13 -interval_list ", label=interval_list, lp="1340.5,607.5", pos="e,1601.5,588.55 1281.8,628.63 1290.5,624.3 1300.7,618.56 1309,612 1313.2,608.67 1312.2,605.31 1317,603 1333.1,595.3 1459.2,595.91 \ 1477,595 1515.8,593.02 1559.4,590.75 1593.2,588.99"]; interval_list -> pindel [_draw_="c 7 -#000000 B 10 1246.28 628.51 1239.01 625.24 1230.27 621.84 1222 620 1202.35 615.63 1054.92 626.55 1041 612 1023.45 593.66 1094.68 \ 587.96 1154.67 586.34 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1154.59 588.79 1161.53 586.17 1154.48 583.89 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1064.5 605.6 0 47 13 -interval_list ", label=interval_list, lp="1064.5,607.5", pos="e,1163,586.14 1246.3,628.51 1239,625.24 1230.3,621.84 1222,620 1202.3,615.63 1054.9,626.55 1041,612 1023.5,593.66 1094.7,587.96 \ 1154.7,586.34"]; varscan [_draw_="c 7 -#000000 C 7 -#f3cea1 P 4 1919.5 575.5 1919.5 594.5 2022.5 594.5 2022.5 575.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1971 582.5 0 87 16 -Varscan Workflow ", fillcolor="#F3CEA1", height=0.27778, label="Varscan Workflow", pos="1971,585", rects="1919.5,575.5,2022.5,594.5", width=1.4306]; interval_list -> varscan [_draw_="c 7 -#000000 B 13 1279.31 628.62 1286.66 625.28 1295.56 621.8 1304 620 1336.72 613.03 1574.66 626.11 1605 612 1609.85 609.74 1608.17 \ 605.31 1613 603 1626.19 596.69 1813.12 590.48 1911.47 587.63 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1911.39 590.08 1918.32 587.43 1911.25 585.18 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1636.5 605.6 0 47 13 -interval_list ", label=interval_list, lp="1636.5,607.5", pos="e,1919.8,587.38 1279.3,628.62 1286.7,625.28 1295.6,621.8 1304,620 1336.7,613.03 1574.7,626.11 1605,612 1609.9,609.74 1608.2,605.31 \ 1613,603 1626.2,596.69 1813.1,590.48 1911.5,587.63"]; varscan_strand_filter -> varscan [_draw_="c 7 -#000000 B 10 1806.16 628.59 1817.45 625.4 1830.76 622.06 1843 620 1866.95 615.98 1930.76 623.78 1952 612 1956.4 609.56 1960.05 \ 605.62 1962.94 601.54 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1964.99 602.88 1966.53 595.63 1960.81 600.34 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1985.5 605.6 0 49 13 -strand_filter ", label=strand_filter, lp="1985.5,607.5", pos="e,1967.3,594.33 1806.2,628.59 1817.5,625.4 1830.8,622.06 1843,620 1867,615.98 1930.8,623.78 1952,612 1956.4,609.56 1960.1,605.62 \ 1962.9,601.54"]; tumor_cram_to_bam [_draw_="c 7 -#000000 C 7 -#f3cea1 P 4 2622.5 575.5 2622.5 594.5 2753.5 594.5 2753.5 575.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2688 582.5 0 115 20 -cram_to_bam workflow ", fillcolor="#F3CEA1", height=0.27778, label="cram_to_bam workflow", pos="2688,585", rects="2622.5,575.5,2753.5,594.5", width=1.8194]; reference -> tumor_cram_to_bam [_draw_="c 7 -#000000 B 10 2519.42 628.67 2525.66 625.57 2533.03 622.27 2540 620 2558.07 614.12 2563.43 616.04 2582 612 2603.71 607.27 2627.77 \ 601.42 2647.47 596.47 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2647.97 598.87 2654.16 594.78 2646.77 594.12 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2640 605.6 0 40 9 -reference ", label=reference, lp="2640,607.5", pos="e,2655.6,594.41 2519.4,628.67 2525.7,625.57 2533,622.27 2540,620 2558.1,614.12 2563.4,616.04 2582,612 2603.7,607.27 2627.8,601.42 \ 2647.5,596.47"]; normal_bam_readcount [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 2820 395.5 2820 414.5 2930 414.5 2930 395.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2875 402.5 0 94 17 -run bam-readcount ", height=0.27778, label="run bam-readcount", pos="2875,405", rects="2820,395.5,2930,414.5", width=1.5278]; reference -> normal_bam_readcount [_draw_="c 7 -#000000 B 16 2518.22 628.67 2524.65 625.33 2532.48 621.85 2540 620 2582.12 609.64 2693.82 625.61 2735 612 2784.07 595.79 2764.65 \ 554.09 2796 513 2817.99 484.18 2838 490.24 2858 460 2865.53 448.61 2869.89 433.69 2872.31 422.42 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2874.67 423.12 2873.57 415.78 2869.86 422.2 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2828.5 515.6 0 65 15 -reference_fasta ", label=reference_fasta, lp="2828.5,517.5", pos="e,2873.9,414.3 2518.2,628.67 2524.7,625.33 2532.5,621.85 2540,620 2582.1,609.64 2693.8,625.61 2735,612 2784.1,595.79 2764.7,554.09 \ 2796,513 2818,484.18 2838,490.24 2858,460 2865.5,448.61 2869.9,433.69 2872.3,422.42"]; reference -> mutect [_draw_="c 7 -#000000 B 13 2490.23 628.54 2483.99 625.18 2476.37 621.72 2469 620 2386.75 600.85 1031.82 628.51 949 612 938.64 609.93 937.28 \ 605.43 927 603 879.26 591.71 824.31 587.42 780.91 585.98 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 781.25 583.54 774.18 585.78 781.11 588.43 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 969 605.6 0 40 9 -reference ", label=reference, lp="969,607.5", pos="e,772.67,585.73 2490.2,628.54 2484,625.18 2476.4,621.72 2469,620 2386.8,600.85 1031.8,628.51 949,612 938.64,609.93 937.28,605.43 \ 927,603 879.26,591.71 824.31,587.42 780.91,585.98"]; reference -> docm [_draw_="c 7 -#000000 B 16 2490.22 628.59 2483.98 625.24 2476.36 621.76 2469 620 2421.34 608.58 2075.45 624.24 2028 612 2019.72 609.86 2019.28 \ 605.14 2011 603 1966.78 591.56 1645.65 596.54 1600 595 1561.21 593.69 1517.91 591.64 1482.76 589.83 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1483.09 587.4 1475.98 589.48 1482.84 592.29 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2048 605.6 0 40 9 -reference ", label=reference, lp="2048,607.5", pos="e,1474.5,589.4 2490.2,628.59 2484,625.24 2476.4,621.76 2469,620 2421.3,608.58 2075.5,624.24 2028,612 2019.7,609.86 2019.3,605.14 \ 2011,603 1966.8,591.56 1645.6,596.54 1600,595 1561.2,593.69 1517.9,591.64 1482.8,589.83"]; filter_vcf [_draw_="c 7 -#000000 C 7 -#f3cea1 P 4 3131 215.5 3131 234.5 3259 234.5 3259 215.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3195 222.5 0 112 25 -Apply filters to VCF file ", fillcolor="#F3CEA1", height=0.27778, label="Apply filters to VCF file", pos="3195,225", rects="3131,215.5,3259,234.5", width=1.7778]; reference -> filter_vcf [_draw_="c 7 -#000000 B 31 2518.22 628.66 2524.65 625.32 2532.48 621.84 2540 620 2584.72 609.06 2703.56 627.25 2747 612 2758.99 607.79 2761.91 \ 604.81 2770 595 2790.36 570.31 2774.39 547.78 2801 530 2815.15 520.54 2937.27 525.12 2954 522 3040.9 505.77 3067.69 506.3 3143 460 \ 3143.09 459.94 3187.95 415.1 3188 415 3194.9 402.43 3195 397.84 3195 383.5 3195 383.5 3195 383.5 3195 269 3195 260.31 3195 250.63 \ 3195 242.65 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3197.45 242.76 3195 235.76 3192.55 242.76 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3199 425.6 0 40 9 -reference ", label=reference, lp="3199,427.5", pos="e,3195,234.24 2518.2,628.66 2524.6,625.32 2532.5,621.84 2540,620 2584.7,609.06 2703.6,627.25 2747,612 2759,607.79 2761.9,604.81 \ 2770,595 2790.4,570.31 2774.4,547.78 2801,530 2815.2,520.54 2937.3,525.12 2954,522 3040.9,505.77 3067.7,506.3 3143,460 3143.1,459.94 \ 3187.9,415.1 3188,415 3194.9,402.43 3195,397.84 3195,383.5 3195,383.5 3195,383.5 3195,269 3195,260.31 3195,250.63 3195,242.65"]; combine [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 1657.5 530.5 1657.5 549.5 1812.5 549.5 1812.5 530.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1735 537.5 0 139 26 -CombineVariants (GATK 3.6) ", height=0.27778, label="CombineVariants (GATK 3.6)", pos="1735,540", rects="1657.5,530.5,1812.5,549.5", width=2.1528]; reference -> combine [_draw_="c 7 -#000000 B 10 2521.1 628.61 2538.86 619.49 2564.76 604.9 2570 595 2574.16 587.14 2576.16 581.41 2570 575 2544.36 548.29 2028.5 \ 542.56 1820.67 541.33 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1820.73 538.88 1813.72 541.29 1820.71 543.78 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2593 583.1 0 40 9 -reference ", label=reference, lp="2593,585", pos="e,1812.2,541.28 2521.1,628.61 2538.9,619.49 2564.8,604.9 2570,595 2574.2,587.14 2576.2,581.41 2570,575 2544.4,548.29 2028.5,542.56 \ 1820.7,541.33"]; annotate_variants [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 2684.5 440.5 2684.5 459.5 2857.5 459.5 2857.5 440.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2771 447.5 0 157 32 -Ensembl Variant Effect Predictor ", height=0.27778, label="Ensembl Variant Effect Predictor", pos="2771,450", rects="2684.5,440.5,2857.5,459.5", width=2.4028]; reference -> annotate_variants [_draw_="c 7 -#000000 B 13 2518.59 628.58 2524.96 625.31 2532.64 621.91 2540 620 2586.35 607.99 2723.34 631.77 2754 595 2784.5 558.42 2663.3 \ 555.4 2685 513 2696.92 489.71 2722.11 473.17 2742.17 463.06 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2743.23 465.27 2748.47 460.03 2741.1 460.86 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2728 538.1 0 40 9 -reference ", label=reference, lp="2728,540", pos="e,2749.8,459.38 2518.6,628.58 2525,625.31 2532.6,621.91 2540,620 2586.3,607.99 2723.3,631.77 2754,595 2784.5,558.42 2663.3,555.4 \ 2685,513 2696.9,489.71 2722.1,473.17 2742.2,463.06"]; tumor_bam_readcount [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 2507 395.5 2507 414.5 2617 414.5 2617 395.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2562 402.5 0 94 17 -run bam-readcount ", height=0.27778, label="run bam-readcount", pos="2562,405", rects="2507,395.5,2617,414.5", width=1.5278]; reference -> tumor_bam_readcount [_draw_="c 7 -#000000 B 16 2500.86 628.58 2497.46 620.67 2491.24 609.16 2482 603 2465.46 591.97 2451.43 609.66 2438 595 2421.72 577.23 2433 \ 565.1 2433 541 2433 541 2433 541 2433 449 2433 433.66 2466.26 422.81 2499 415.85 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2499.44 418.26 2505.81 414.46 2498.46 413.46 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2465.5 515.6 0 65 15 -reference_fasta ", label=reference_fasta, lp="2465.5,517.5", pos="e,2507.3,414.16 2500.9,628.58 2497.5,620.67 2491.2,609.16 2482,603 2465.5,591.97 2451.4,609.66 2438,595 2421.7,577.23 2433,565.1 \ 2433,541 2433,541 2433,541 2433,449 2433,433.66 2466.3,422.81 2499,415.85"]; reference -> strelka [_draw_="c 7 -#000000 B 13 2490.21 628.62 2483.97 625.27 2476.35 621.8 2469 620 2405.29 604.43 2237.62 627.93 2174 612 2165.32 609.83 2164.67 \ 605.2 2156 603 2156 603 1838.46 592.33 1706.48 587.9 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1706.65 585.45 1699.57 587.67 1706.49 590.35 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2194 605.6 0 40 9 -reference ", label=reference, lp="2194,607.5", pos="e,1698.1,587.61 2490.2,628.62 2484,625.27 2476.3,621.8 2469,620 2405.3,604.43 2237.6,627.93 2174,612 2165.3,609.83 2164.7,605.2 \ 2156,603 2156,603 1838.5,592.33 1706.5,587.9"]; reference -> pindel [_draw_="c 7 -#000000 B 16 2490.23 628.57 2483.98 625.21 2476.36 621.74 2469 620 2432.56 611.39 1829.07 627.54 1795 612 1790.13 609.78 1791.86 \ 605.24 1787 603 1764.94 592.85 1374.26 596.13 1350 595 1335.47 594.32 1319.97 593.35 1305.11 592.29 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1305.59 589.87 1298.43 591.8 1305.23 594.75 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1815 605.6 0 40 9 -reference ", label=reference, lp="1815,607.5", pos="e,1296.9,591.69 2490.2,628.57 2484,625.21 2476.4,621.74 2469,620 2432.6,611.39 1829.1,627.54 1795,612 1790.1,609.78 1791.9,605.24 \ 1787,603 1764.9,592.85 1374.3,596.13 1350,595 1335.5,594.32 1320,593.35 1305.1,592.29"]; normal_cram_to_bam [_draw_="c 7 -#000000 C 7 -#f3cea1 P 4 2438.5 575.5 2438.5 594.5 2569.5 594.5 2569.5 575.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2504 582.5 0 115 20 -cram_to_bam workflow ", fillcolor="#F3CEA1", height=0.27778, label="cram_to_bam workflow", pos="2504,585", rects="2438.5,575.5,2569.5,594.5", width=1.8194]; reference -> normal_cram_to_bam [_draw_="c 7 -#000000 B 4 2504 628.58 2504 621.52 2504 611.24 2504 602.55 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2506.45 602.78 2504 595.78 2501.55 602.78 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2524 605.6 0 40 9 -reference ", label=reference, lp="2524,607.5", pos="e,2504,594.26 2504,628.58 2504,621.52 2504,611.24 2504,602.55"]; reference -> varscan [_draw_="c 7 -#000000 B 10 2488.27 628.51 2482.34 625.54 2475.47 622.36 2469 620 2454.57 614.73 2417.2 605.2 2402 603 2332.17 592.88 2131.59 \ 588.45 2030.6 586.81 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2030.88 584.37 2023.84 586.7 2030.8 589.27 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2462 605.6 0 40 9 -reference ", label=reference, lp="2462,607.5", pos="e,2022.3,586.68 2488.3,628.51 2482.3,625.54 2475.5,622.36 2469,620 2454.6,614.73 2417.2,605.2 2402,603 2332.2,592.88 2131.6,588.45 \ 2030.6,586.81"]; variants_to_table [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 3290.5 72.5 3290.5 91.5 3431.5 91.5 3431.5 72.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3361 79.5 0 125 25 -SelectVariants (GATK 3.6) ", height=0.27778, label="SelectVariants (GATK 3.6)", pos="3361,82", rects="3290.5,72.5,3431.5,91.5", width=1.9583]; reference -> variants_to_table [_draw_="c 7 -#000000 B 28 2518.22 628.65 2524.65 625.31 2532.48 621.83 2540 620 2587.1 608.53 2710.03 619.02 2758 612 2866.58 596.12 2906.86 \ 612.59 2997 550 3005.91 543.81 3001.48 535.2 3011 530 3031.11 519.03 3200 537.35 3217 522 3249.98 492.21 3204.71 458.82 3231 423 \ 3268.87 371.39 3361 425.01 3361 361 3361 361 3361 361 3361 134 3361 122.59 3361 109.75 3361 99.81 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3363.45 99.82 3361 92.82 3358.55 99.82 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3381 358.1 0 40 9 -reference ", label=reference, lp="3381,360", pos="e,3361,91.304 2518.2,628.65 2524.6,625.31 2532.5,621.83 2540,620 2587.1,608.53 2710,619.02 2758,612 2866.6,596.12 2906.9,612.59 \ 2997,550 3005.9,543.81 3001.5,535.2 3011,530 3031.1,519.03 3200,537.35 3217,522 3250,492.21 3204.7,458.82 3231,423 3268.9,371.39 \ 3361,425.01 3361,361 3361,361 3361,361 3361,134 3361,122.59 3361,109.75 3361,99.808"]; varscan_min_coverage -> varscan [_draw_="c 7 -#000000 B 13 1936.32 628.58 1948.5 625.39 1962.83 622.05 1976 620 1989.09 617.96 2085.95 621.68 2095 612 2097.73 609.08 2097.63 \ 606.01 2095 603 2086.36 593.09 2058.19 588.75 2030.88 586.93 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2031.1 584.49 2023.97 586.53 2030.81 589.38 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2126 605.6 0 58 12 -min_coverage ", label=min_coverage, lp="2126,607.5", pos="e,2022.5,586.44 1936.3,628.58 1948.5,625.39 1962.8,622.05 1976,620 1989.1,617.96 2085.9,621.68 2095,612 2097.7,609.08 2097.6,606.01 \ 2095,603 2086.4,593.09 2058.2,588.75 2030.9,586.93"]; add_vep_fields_to_table [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 3036.5 0.5 3036.5 19.5 3193.5 19.5 3193.5 0.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3115 7.5 0 141 28 -add VEP annotation to report ", height=0.27778, label="add VEP annotation to report", pos="3115,10", rects="3036.5,0.5,3193.5,19.5", width=2.1806]; vep_to_table_fields -> add_vep_fields_to_table [_draw_="c 7 -#000000 B 16 2414.47 628.87 2416.78 615.36 2421 587.37 2421 563.5 2421 563.5 2421 563.5 2421 404 2421 203.63 2891.56 218.84 \ 2957 190 3023.33 160.77 3051.22 159.23 3093 100 3108.37 78.2 3113.05 46.81 3114.44 27.72 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3116.88 28.07 3114.81 20.94 3111.98 27.8 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2466 335.6 0 42 10 -vep_fields ", label=vep_fields, lp="2466,337.5", pos="e,3114.9,19.431 2414.5,628.87 2416.8,615.36 2421,587.37 2421,563.5 2421,563.5 2421,563.5 2421,404 2421,203.63 2891.6,218.84 2957,\ 190 3023.3,160.77 3051.2,159.23 3093,100 3108.4,78.203 3113,46.806 3114.4,27.717"]; tumor_cram -> tumor_cram_to_bam [_draw_="c 7 -#000000 B 13 1444.72 628.56 1452.24 625.2 1461.36 621.73 1470 620 1510.37 611.91 2173.54 629.07 2211 612 2215.87 609.78 2214.14 \ 605.24 2219 603 2238 594.24 2556.08 596.36 2616.98 594.82 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2616.82 597.28 2623.72 594.55 2616.62 592.38 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2229.5 605.6 0 21 4 -cram ", label=cram, lp="2229.5,607.5", pos="e,2625.2,594.48 1444.7,628.56 1452.2,625.2 1461.4,621.73 1470,620 1510.4,611.91 2173.5,629.07 2211,612 2215.9,609.78 2214.1,605.24 \ 2219,603 2238,594.24 2556.1,596.36 2617,594.82"]; tumor_cram -> mutect [_draw_="c 7 -#000000 B 13 1411.28 628.58 1403.75 625.23 1394.63 621.75 1386 620 1331 608.84 934.1 630.17 881 612 874.69 609.84 875.21 605.43 \ 869 603 852.99 596.73 816.01 592.61 781.1 590 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 781.43 587.57 774.27 589.51 781.08 592.46 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 905.5 605.6 0 49 10 -tumor_cram ", label=tumor_cram, lp="905.5,607.5", pos="e,772.76,589.4 1411.3,628.58 1403.8,625.23 1394.6,621.75 1386,620 1331,608.84 934.1,630.17 881,612 874.69,609.84 875.21,605.43 869,\ 603 852.99,596.73 816.01,592.61 781.1,590"]; tumor_cram -> docm [_draw_="c 7 -#000000 B 7 1429.23 628.6 1429.92 621.54 1430.11 611.29 1427 603 1426.78 602.41 1426.53 601.82 1426.25 601.25 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1428.39 600.03 1422.48 595.55 1424.3 602.74 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1453.5 605.6 0 49 10 -tumor_cram ", label=tumor_cram, lp="1453.5,607.5", pos="e,1421.6,594.29 1429.2,628.6 1429.9,621.54 1430.1,611.29 1427,603 1426.8,602.41 1426.5,601.82 1426.3,601.25"]; tumor_cram -> strelka [_draw_="c 7 -#000000 B 13 1445.62 628.58 1452.99 625.4 1461.76 622.05 1470 620 1503.39 611.69 1514.97 624.55 1547 612 1553.21 609.57 1552.9 \ 605.68 1559 603 1569.76 598.27 1581.8 594.86 1593.5 592.39 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1593.65 594.86 1600.05 591.12 1592.71 590.05 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1583.5 605.6 0 49 10 -tumor_cram ", label=tumor_cram, lp="1583.5,607.5", pos="e,1601.5,590.83 1445.6,628.58 1453,625.4 1461.8,622.05 1470,620 1503.4,611.69 1515,624.55 1547,612 1553.2,609.57 1552.9,605.68 1559,\ 603 1569.8,598.27 1581.8,594.86 1593.5,592.39"]; tumor_cram -> pindel [_draw_="c 7 -#000000 B 10 1410.83 628.6 1403.38 625.34 1394.44 621.93 1386 620 1359.3 613.89 1288.58 621.81 1263 612 1261.95 611.6 1254.24 \ 605.54 1246.54 599.37 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1248.38 597.71 1241.39 595.24 1245.31 601.53 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1287.5 605.6 0 49 10 -tumor_cram ", label=tumor_cram, lp="1287.5,607.5", pos="e,1240.2,594.29 1410.8,628.6 1403.4,625.34 1394.4,621.93 1386,620 1359.3,613.89 1288.6,621.81 1263,612 1261.9,611.6 1254.2,605.54 \ 1246.5,599.37"]; tumor_cram -> varscan [_draw_="c 7 -#000000 B 13 1444.73 628.6 1452.25 625.25 1461.37 621.78 1470 620 1509.84 611.79 1799.08 629.07 1836 612 1840.86 609.75 1839.27 \ 605.51 1844 603 1855.75 596.75 1884.25 592.63 1911.28 590.02 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1911.35 592.47 1918.09 589.39 1910.9 587.59 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1868.5 605.6 0 49 10 -tumor_cram ", label=tumor_cram, lp="1868.5,607.5", pos="e,1919.6,589.25 1444.7,628.6 1452.3,625.25 1461.4,621.78 1470,620 1509.8,611.79 1799.1,629.07 1836,612 1840.9,609.75 1839.3,605.51 \ 1844,603 1855.7,596.75 1884.2,592.63 1911.3,590.02"]; readcount_minimum_base_quality -> normal_bam_readcount [_draw_="c 7 -#000000 B 13 2965.26 628.53 3040.04 614.84 3159 583.8 3112 530 3094.59 510.07 3075.35 536.17 3053 522 3036.45 511.5 3042.57 \ 499.14 3029 485 2996.44 451.08 2946.16 429.12 2911.98 417.16 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2912.93 414.9 2905.52 414.96 2911.36 419.54 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3088.5 515.6 0 71 16 -min_base_quality ", label=min_base_quality, lp="3088.5,517.5", pos="e,2904.1,414.48 2965.3,628.53 3040,614.84 3159,583.8 3112,530 3094.6,510.07 3075.3,536.17 3053,522 3036.4,511.5 3042.6,499.14 3029,\ 485 2996.4,451.08 2946.2,429.12 2912,417.16"]; readcount_minimum_base_quality -> tumor_bam_readcount [_draw_="c 7 -#000000 B 19 2900.63 628.72 2877.03 608.35 2812.5 555.6 2749 530 2730.57 522.57 2721.32 533.34 2705 522 2689.29 511.09 2695.16 \ 499.77 2683 485 2675.8 476.25 2674.32 472.67 2664 468 2637.08 455.81 2623.16 475.49 2598 460 2583.67 451.18 2573.81 434.28 2568.08 \ 421.73 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2570.48 421.12 2565.5 415.63 2565.97 423.03 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2740.5 515.6 0 71 16 -min_base_quality ", label=min_base_quality, lp="2740.5,517.5", pos="e,2564.9,414.23 2900.6,628.72 2877,608.35 2812.5,555.6 2749,530 2730.6,522.57 2721.3,533.34 2705,522 2689.3,511.09 2695.2,499.77 \ 2683,485 2675.8,476.25 2674.3,472.67 2664,468 2637.1,455.81 2623.2,475.49 2598,460 2583.7,451.18 2573.8,434.28 2568.1,421.73"]; cosmic_vcf -> mutect [_draw_="c 7 -#000000 B 13 688.12 628.57 681.21 625.31 672.9 621.9 665 620 650.93 616.61 544.91 622.54 535 612 532.26 609.09 532.32 605.97 \ 535 603 541.47 595.85 585.43 591.57 626.9 589.09 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 626.78 591.55 633.63 588.71 626.5 586.66 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 557.5 605.6 0 45 10 -cosmic_vcf ", label=cosmic_vcf, lp="557.5,607.5", pos="e,635.14,588.62 688.12,628.57 681.21,625.31 672.9,621.9 665,620 650.93,616.61 544.91,622.54 535,612 532.26,609.09 532.32,605.97 \ 535,603 541.47,595.85 585.43,591.57 626.9,589.09"]; varscan_min_var_freq -> varscan [_draw_="c 7 -#000000 B 13 2066.45 628.51 2078.27 625.32 2092.19 621.98 2105 620 2119.96 617.68 2230.62 623.01 2241 612 2243.74 609.09 2243.74 \ 605.92 2241 603 2226.93 588.02 2105.92 585.58 2030.75 585.53 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2030.79 583.08 2023.79 585.53 2030.79 587.98 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2269 605.6 0 52 12 -min_var_freq ", label=min_var_freq, lp="2269,607.5", pos="e,2022.3,585.53 2066.4,628.51 2078.3,625.32 2092.2,621.98 2105,620 2120,617.68 2230.6,623.01 2241,612 2243.7,609.09 2243.7,605.92 \ 2241,603 2226.9,588.02 2105.9,585.58 2030.8,585.53"]; strelka_exome_mode -> strelka [_draw_="c 7 -#000000 B 10 1682.25 628.51 1693.78 625.28 1707.43 621.91 1720 620 1758.41 614.16 1920.5 631.41 1894 603 1881.48 589.57 1774.49 \ 586.53 1706.4 585.97 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1706.83 583.52 1699.81 585.92 1706.8 588.42 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1923.5 605.6 0 55 10 -exome_mode ", label=exome_mode, lp="1923.5,607.5", pos="e,1698.3,585.91 1682.2,628.51 1693.8,625.28 1707.4,621.91 1720,620 1758.4,614.16 1920.5,631.41 1894,603 1881.5,589.57 1774.5,586.53 \ 1706.4,585.97"]; normal_cram -> mutect [_draw_="c 7 -#000000 B 13 1327.44 628.58 1319.55 625.23 1310 621.76 1301 620 1248.43 609.75 869.67 629.36 819 612 812.69 609.84 813.13 605.62 \ 807 603 798.83 599.51 790.02 596.74 781.1 594.53 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 781.75 592.16 774.38 592.99 780.66 596.94 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 845.5 605.6 0 53 11 -normal_cram ", label=normal_cram, lp="845.5,607.5", pos="e,772.9,592.66 1327.4,628.58 1319.5,625.23 1310,621.76 1301,620 1248.4,609.75 869.67,629.36 819,612 812.69,609.84 813.13,605.62 \ 807,603 798.83,599.51 790.02,596.74 781.1,594.53"]; normal_cram -> docm [_draw_="c 7 -#000000 B 7 1351.64 628.74 1359.5 618.99 1371.68 603.98 1373 603 1375.38 601.22 1377.97 599.59 1380.65 598.1 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1381.36 600.49 1386.52 595.17 1379.17 596.1 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1399.5 605.6 0 53 11 -normal_cram ", label=normal_cram, lp="1399.5,607.5", pos="e,1387.9,594.49 1351.6,628.74 1359.5,618.99 1371.7,603.98 1373,603 1375.4,601.22 1378,599.59 1380.6,598.1"]; normal_cram -> strelka [_draw_="c 7 -#000000 B 13 1363.92 628.55 1371.83 625.36 1381.21 622.02 1390 620 1428.71 611.12 1441.43 624.89 1479 612 1486 609.6 1486.03 \ 605.46 1493 603 1525.02 591.69 1562.8 587.34 1593.28 585.87 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1593.27 588.32 1600.16 585.59 1593.07 583.43 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1519.5 605.6 0 53 11 -normal_cram ", label=normal_cram, lp="1519.5,607.5", pos="e,1601.7,585.53 1363.9,628.55 1371.8,625.36 1381.2,622.02 1390,620 1428.7,611.12 1441.4,624.89 1479,612 1486,609.6 1486,605.46 1493,\ 603 1525,591.69 1562.8,587.34 1593.3,585.87"]; normal_cram -> pindel [_draw_="c 7 -#000000 B 13 1327.42 628.68 1319.53 625.34 1309.98 621.86 1301 620 1289.89 617.7 1104.86 620.18 1097 612 1094.23 609.12 1094.36 \ 606 1097 603 1105.15 593.74 1129.37 589.23 1154.94 587.13 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1154.96 589.59 1161.76 586.64 1154.6 584.7 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1123.5 605.6 0 53 11 -normal_cram ", label=normal_cram, lp="1123.5,607.5", pos="e,1163.3,586.53 1327.4,628.68 1319.5,625.34 1310,621.86 1301,620 1289.9,617.7 1104.9,620.18 1097,612 1094.2,609.12 1094.4,606 1097,\ 603 1105.2,593.74 1129.4,589.23 1154.9,587.13"]; normal_cram -> normal_cram_to_bam [_draw_="c 7 -#000000 B 13 1362.97 628.56 1371.05 625.21 1380.81 621.73 1390 620 1426.85 613.05 2030.88 627.57 2065 612 2069.87 609.78 2068.16 \ 605.29 2073 603 2104.33 588.18 2315.72 585.91 2430.38 585.78 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2430.29 588.23 2437.28 585.78 2430.28 583.33 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2083.5 605.6 0 21 4 -cram ", label=cram, lp="2083.5,607.5", pos="e,2438.8,585.77 1363,628.56 1371,625.21 1380.8,621.73 1390,620 1426.9,613.05 2030.9,627.57 2065,612 2069.9,609.78 2068.2,605.29 \ 2073,603 2104.3,588.18 2315.7,585.91 2430.4,585.78"]; normal_cram -> varscan [_draw_="c 7 -#000000 B 13 1362.98 628.62 1371.06 625.27 1380.82 621.79 1390 620 1461.78 605.99 1648.03 629.67 1719 612 1727.68 609.84 1728.38 \ 605.37 1737 603 1768.59 594.32 1852.85 589.84 1911.13 587.7 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1911.11 590.16 1918.02 587.46 1910.94 585.26 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1763.5 605.6 0 53 11 -normal_cram ", label=normal_cram, lp="1763.5,607.5", pos="e,1919.5,587.41 1363,628.62 1371.1,625.27 1380.8,621.79 1390,620 1461.8,605.99 1648,629.67 1719,612 1727.7,609.84 1728.4,605.37 \ 1737,603 1768.6,594.32 1852.9,589.84 1911.1,587.7"]; filter_mapq0_threshold -> filter_vcf [_draw_="c 7 -#000000 B 13 3469.43 628.5 3457.57 625.38 3443.73 622.11 3431 620 3387.6 612.82 3236 629.99 3236 586 3236 586 3236 586 3236 \ 269 3236 256.72 3227.13 246.55 3217.64 239.2 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3219.11 237.24 3211.97 235.22 3216.29 241.25 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3283 425.6 0 94 22 -filter_mapq0_threshold ", label=filter_mapq0_threshold, lp="3283,427.5", pos="e,3210.7,234.35 3469.4,628.5 3457.6,625.38 3443.7,622.11 3431,620 3387.6,612.82 3236,629.99 3236,586 3236,586 3236,586 3236,269 \ 3236,256.72 3227.1,246.55 3217.6,239.2"]; mutect_scatter_count -> mutect [_draw_="c 7 -#000000 B 13 777.74 628.56 766.21 625.33 752.56 621.95 740 620 723.4 617.42 600.56 624.19 589 612 586.25 609.1 586.39 606.03 \ 589 603 594.72 596.38 609.76 592.29 627.15 589.78 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 627.15 592.25 633.78 588.93 626.52 587.39 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 617 605.6 0 56 13 -scatter_count ", label=scatter_count, lp="617,607.5", pos="e,635.28,588.73 777.74,628.56 766.21,625.33 752.56,621.95 740,620 723.4,617.42 600.56,624.19 589,612 586.25,609.1 586.39,606.03 \ 589,603 594.72,596.38 609.76,592.29 627.15,589.78"]; strelka_cpu_reserved -> strelka [_draw_="c 7 -#000000 B 10 1558.48 628.52 1569.49 625.48 1582.26 622.25 1594 620 1608.73 617.18 1651.05 623.21 1661 612 1663.63 609.04 1663.5 \ 605.36 1662.1 601.71 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1664.3 600.62 1658.66 595.8 1660.07 603.09 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1690.5 605.6 0 55 12 -cpu_reserved ", label=cpu_reserved, lp="1690.5,607.5", pos="e,1657.9,594.5 1558.5,628.52 1569.5,625.48 1582.3,622.25 1594,620 1608.7,617.18 1651,623.21 1661,612 1663.6,609.04 1663.5,605.36 \ 1662.1,601.71"]; docm_vcf -> docm [_draw_="c 7 -#000000 B 10 1177.19 628.74 1167.61 621.57 1157.36 611.11 1165 603 1175.23 592.14 1284.12 596.03 1299 595 1313.46 594 1328.93 \ 592.84 1343.68 591.69 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1343.49 594.16 1350.27 591.17 1343.1 589.27 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1184.5 605.6 0 39 8 -docm_vcf ", label=docm_vcf, lp="1184.5,607.5", pos="e,1351.8,591.05 1177.2,628.74 1167.6,621.57 1157.4,611.11 1165,603 1175.2,592.14 1284.1,596.03 1299,595 1313.5,594 1328.9,592.84 \ 1343.7,591.69"]; varscan_max_normal_freq -> varscan [_draw_="c 7 -#000000 B 13 2215.56 628.51 2228.09 625.73 2242.13 622.68 2255 620 2273.18 616.22 2284.2 626.33 2296 612 2298.54 608.91 2298.75 \ 605.9 2296 603 2287.03 593.55 2122.2 588.89 2030.81 587.03 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2031.03 584.58 2023.99 586.89 2030.94 589.48 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2332 605.6 0 70 15 -max_normal_freq ", label=max_normal_freq, lp="2332,607.5", pos="e,2022.5,586.86 2215.6,628.51 2228.1,625.73 2242.1,622.68 2255,620 2273.2,616.22 2284.2,626.33 2296,612 2298.5,608.91 2298.8,605.9 \ 2296,603 2287,593.55 2122.2,588.89 2030.8,587.03"]; custom_gnomad_vcf -> annotate_variants [_draw_="c 7 -#000000 B 16 2718.03 628.55 2728.88 625.52 2741.44 622.28 2753 620 2780.69 614.53 2790.94 624.99 2816 612 2826.96 606.32 2880.04 \ 535.68 2891 530 2903.53 523.51 2944.67 532.59 2954 522 2986.11 485.55 2925.73 467.68 2865.89 459 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2866.23 456.57 2858.96 458.04 2865.56 461.43 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2933 538.1 0 84 17 -custom_gnomad_vcf ", label=custom_gnomad_vcf, lp="2933,540", pos="e,2857.5,457.83 2718,628.55 2728.9,625.52 2741.4,622.28 2753,620 2780.7,614.53 2790.9,624.99 2816,612 2827,606.32 2880,535.68 2891,\ 530 2903.5,523.51 2944.7,532.59 2954,522 2986.1,485.55 2925.7,467.68 2865.9,459"]; annotate_coding_only -> annotate_variants [_draw_="c 7 -#000000 B 13 3050.11 628.62 3034.54 620.28 3015 605.86 3015 586 3015 586 3015 586 3015 494 3015 471.67 2993.24 474.9 2972 468 \ 2952.29 461.6 2907.84 457.48 2865.74 454.91 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2866 452.47 2858.87 454.5 2865.71 457.36 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3039.5 538.1 0 49 11 -coding_only ", label=coding_only, lp="3039.5,540", pos="e,2857.4,454.41 3050.1,628.62 3034.5,620.28 3015,605.86 3015,586 3015,586 3015,586 3015,494 3015,471.67 2993.2,474.9 2972,468 2952.3,\ 461.6 2907.8,457.48 2865.7,454.91"]; cle_vcf_filter -> filter_vcf [_draw_="c 7 -#000000 B 13 3589.41 628.55 3581.78 625.28 3572.63 621.88 3564 620 3514.59 609.26 3339 636.57 3339 586 3339 586 3339 586 3339 \ 269 3339 252.32 3303.09 241.58 3267.14 235 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3267.81 232.63 3260.49 233.84 3266.96 237.46 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3371.5 425.6 0 65 17 -do_cle_vcf_filter ", label=do_cle_vcf_filter, lp="3371.5,427.5", pos="e,3259,233.58 3589.4,628.55 3581.8,625.28 3572.6,621.88 3564,620 3514.6,609.26 3339,636.57 3339,586 3339,586 3339,586 3339,269 3339,\ 252.32 3303.1,241.58 3267.1,235"]; readcount_minimum_mapping_quality -> normal_bam_readcount [_draw_="c 7 -#000000 B 16 3277.48 628.57 3262.3 624.81 3245.97 619.48 3232 612 3173.72 580.8 3175.11 550.98 3121 513 3065.17 473.81 3047.94 \ 468.57 2986 440 2966.96 431.22 2961.97 429.37 2942 423 2934.86 420.72 2927.22 418.55 2919.75 416.56 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2920.59 414.25 2913.2 414.86 2919.36 418.99 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3175.5 515.6 0 87 19 -min_mapping_quality ", label=min_mapping_quality, lp="3175.5,517.5", pos="e,2911.7,414.48 3277.5,628.57 3262.3,624.81 3246,619.48 3232,612 3173.7,580.8 3175.1,550.98 3121,513 3065.2,473.81 3047.9,468.57 \ 2986,440 2967,431.22 2962,429.37 2942,423 2934.9,420.72 2927.2,418.55 2919.7,416.56"]; readcount_minimum_mapping_quality -> tumor_bam_readcount [_draw_="c 7 -#000000 B 19 3279.7 628.54 3168.12 608.85 2900.65 560.83 2884 550 2867.15 539.04 2874.61 524.32 2858 513 2788.42 465.6 2756.82 \ 483.09 2674 468 2644.93 462.7 2633.81 474.38 2608 460 2598.06 454.46 2599.32 448.71 2592 440 2586.5 433.45 2580.26 426.33 2574.9 \ 420.31 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2577.01 419 2570.52 415.41 2573.36 422.26 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2909.5 515.6 0 87 19 -min_mapping_quality ", label=min_mapping_quality, lp="2909.5,517.5", pos="e,2569.5,414.29 3279.7,628.54 3168.1,608.85 2900.6,560.83 2884,550 2867.2,539.04 2874.6,524.32 2858,513 2788.4,465.6 2756.8,483.09 \ 2674,468 2644.9,462.7 2633.8,474.38 2608,460 2598.1,454.46 2599.3,448.71 2592,440 2586.5,433.45 2580.3,426.33 2574.9,420.31"]; synonyms_file -> annotate_variants [_draw_="c 7 -#000000 B 19 2602.72 628.55 2611.25 625.28 2621.46 621.88 2631 620 2648.9 616.47 2781.14 623.86 2795 612 2823.28 587.81 2785.95 \ 556.58 2812 530 2823.17 518.6 2837.05 534.48 2847 522 2849.49 518.87 2848.72 516.61 2847 513 2836.52 490.93 2813.91 474.12 2796.06 \ 463.61 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2797.37 461.53 2790.07 460.24 2794.97 465.8 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2841 538.1 0 58 13 -synonyms_file ", label=synonyms_file, lp="2841,540", pos="e,2788.8,459.49 2602.7,628.55 2611.3,625.28 2621.5,621.88 2631,620 2648.9,616.47 2781.1,623.86 2795,612 2823.3,587.81 2786,556.58 \ 2812,530 2823.2,518.6 2837.1,534.48 2847,522 2849.5,518.87 2848.7,516.61 2847,513 2836.5,490.93 2813.9,474.12 2796.1,463.61"]; filter_gnomADe_maximum_population_allele_frequency -> filter_vcf [_draw_="c 7 -#000000 B 22 3725.75 628.52 3615.18 615.05 3413 589.9 3413 586 3413 586 3413 586 3413 449 3413 436.91 3410.98 433.51 3405 423 \ 3386.79 390.98 3350 397.84 3350 361 3350 361 3350 361 3350 269 3350 257.34 3327.1 246.5 3318 243 3302.09 236.88 3284.28 232.92 3267.25 \ 230.37 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3267.74 227.96 3260.47 229.43 3267.07 232.81 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3522 425.6 0 226 50 -filter_gnomADe_maximum_population_allele_frequency ", label=filter_gnomADe_maximum_population_allele_frequency, lp="3522,427.5", pos="e,3259,229.22 3725.8,628.52 3615.2,615.05 3413,589.9 3413,586 3413,586 3413,586 3413,449 3413,436.91 3411,433.51 3405,423 3386.8,\ 390.98 3350,397.84 3350,361 3350,361 3350,361 3350,269 3350,257.34 3327.1,246.5 3318,243 3302.1,236.88 3284.3,232.92 3267.3,230.37"]; mutect_artifact_detection_mode -> mutect [_draw_="c 7 -#000000 B 10 919.24 628.55 902.89 625.32 883.6 621.95 866 620 854.29 618.7 662.18 620.49 654 612 648.5 606.29 651.49 601.59 \ 658.14 597.84 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 659.07 600.1 664.46 595.01 657.07 595.63 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 704 605.6 0 100 23 -artifact_detection_mode ", label=artifact_detection_mode, lp="704,607.5", pos="e,665.84,594.39 919.24,628.55 902.89,625.32 883.6,621.95 866,620 854.29,618.7 662.18,620.49 654,612 648.5,606.29 651.49,601.59 658.14,\ 597.84"]; panel_of_normals_vcf -> mutect [_draw_="c 7 -#000000 B 7 85.28 628.75 93.14 620.49 106.51 608.27 121 603 167.23 586.17 479.2 585.1 626.84 585.55 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 626.51 588 633.52 585.58 626.53 583.1 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 165 605.6 0 88 20 -panel_of_normals_vcf ", label=panel_of_normals_vcf, lp="165,607.5", pos="e,635.04,585.58 85.275,628.75 93.141,620.49 106.51,608.27 121,603 167.23,586.17 479.2,585.1 626.84,585.55"]; mutect_max_alt_alleles_in_normal_count -> mutect [_draw_="c 7 -#000000 B 7 231.23 628.61 216.88 622.13 202.68 612.65 212 603 226.15 588.35 492.05 586.09 626.92 585.89 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 626.7 588.34 633.7 585.89 626.7 583.44 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 278.5 605.6 0 133 31 -max_alt_alleles_in_normal_count ", label=max_alt_alleles_in_normal_count, lp="278.5,607.5", pos="e,635.21,585.88 231.23,628.61 216.88,622.13 202.68,612.65 212,603 226.15,588.35 492.05,586.09 626.92,585.89"]; varscan_p_value -> varscan [_draw_="c 7 -#000000 B 10 2334.88 628.56 2349.17 623.97 2363.9 618.01 2368 612 2370.26 608.7 2370.77 605.89 2368 603 2356.53 591.03 2138.41 \ 587.45 2030.48 586.41 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2030.81 583.96 2023.78 586.35 2030.76 588.86 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2385 605.6 0 32 7 -p_value ", label=p_value, lp="2385,607.5", pos="e,2022.3,586.33 2334.9,628.56 2349.2,623.97 2363.9,618.01 2368,612 2370.3,608.7 2370.8,605.89 2368,603 2356.5,591.03 2138.4,587.45 \ 2030.5,586.41"]; mutect_max_alt_allele_in_normal_fraction -> mutect [_draw_="c 7 -#000000 B 10 416.22 628.56 384.76 623.79 352.71 617.67 348 612 345.45 608.92 345.24 605.9 348 603 357.47 593.06 524.97 588.73 \ 626.8 587.01 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 626.75 589.46 633.71 586.9 626.67 584.56 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 416.5 605.6 0 137 33 -max_alt_allele_in_normal_fraction ", label=max_alt_allele_in_normal_fraction, lp="416.5,607.5", pos="e,635.22,586.87 416.22,628.56 384.76,623.79 352.71,617.67 348,612 345.45,608.92 345.24,605.9 348,603 357.47,593.06 524.97,588.73 \ 626.8,587.01"]; vep_pick -> annotate_variants [_draw_="c 7 -#000000 B 16 2797.09 628.53 2803.04 625.34 2810.16 622 2817 620 2852.51 609.6 2980 623 2980 586 2980 586 2980 586 2980 494 \ 2980 479.95 2974.15 475.07 2962 468 2945.41 458.35 2905.02 453.94 2865.64 452.01 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2865.87 449.57 2858.77 451.71 2865.65 454.47 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2988.5 538.1 0 17 4 -pick ", label=pick, lp="2988.5,540", pos="e,2857.3,451.64 2797.1,628.53 2803,625.34 2810.2,622 2817,620 2852.5,609.6 2980,623 2980,586 2980,586 2980,586 2980,494 2980,479.95 \ 2974.1,475.07 2962,468 2945.4,458.35 2905,453.94 2865.6,452.01"]; variants_to_table_genotype_fields -> variants_to_table [_draw_="c 7 -#000000 B 10 4134.42 628.52 4097.92 619.7 4050 604.57 4050 586 4050 586 4050 586 4050 134 4050 103.71 3620.83 89.46 3439.92 \ 84.8 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3440.07 82.36 3433.01 84.63 3439.95 87.26 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 4083 358.1 0 66 15 -genotype_fields ", label=genotype_fields, lp="4083,360", pos="e,3431.5,84.59 4134.4,628.52 4097.9,619.7 4050,604.57 4050,586 4050,586 4050,586 4050,134 4050,103.71 3620.8,89.463 3439.9,84.805"]; variants_to_table_fields -> variants_to_table [_draw_="c 7 -#000000 B 13 3978.6 628.59 3967.03 625.75 3953.97 622.64 3942 620 3904.17 611.65 3771 624.74 3771 586 3771 586 3771 586 3771 \ 134 3771 100.99 3559 89.08 3439.89 85 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3440.07 82.55 3432.99 84.77 3439.91 87.45 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3782.5 358.1 0 23 6 -fields ", label=fields, lp="3782.5,360", pos="e,3431.5,84.717 3978.6,628.59 3967,625.75 3954,622.64 3942,620 3904.2,611.65 3771,624.74 3771,586 3771,586 3771,586 3771,134 3771,\ 100.99 3559,89.083 3439.9,84.998"]; vep_cache_dir -> annotate_variants [_draw_="c 7 -#000000 B 22 3154.27 628.52 3144.62 624.41 3133.72 618.86 3125 612 3097.17 590.12 3094.72 579.4 3075 550 3069.35 541.57 3071.6 \ 536.72 3064 530 3056.83 523.66 3051.45 528.01 3044 522 3028.55 509.54 3033.26 498.81 3019 485 3008.81 475.14 3005.46 472.45 2992 \ 468 2968.9 460.36 2914.71 456.12 2865.78 453.79 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2865.96 451.34 2858.86 453.47 2865.74 456.24 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3095 538.1 0 40 9 -cache_dir ", label=cache_dir, lp="3095,540", pos="e,2857.3,453.4 3154.3,628.52 3144.6,624.41 3133.7,618.86 3125,612 3097.2,590.12 3094.7,579.4 3075,550 3069.3,541.57 3071.6,536.72 \ 3064,530 3056.8,523.66 3051.5,528.01 3044,522 3028.5,509.54 3033.3,498.81 3019,485 3008.8,475.14 3005.5,472.45 2992,468 2968.9,460.36 \ 2914.7,456.12 2865.8,453.79"]; tumor_cram_to_bam -> filter_vcf [_draw_="c 7 -#000000 B 28 2705.76 575.52 2718.3 569.2 2735.26 559.97 2749 550 2768.6 535.78 2767.24 523.63 2789 513 2900.28 458.65 2941.32 \ 484.94 3064 468 3079.73 465.83 3123.55 471 3135 460 3156.08 439.75 3131.79 421.07 3145 395 3152.1 380.98 3162.44 383.77 3170 370 \ 3176.9 357.43 3177 352.84 3177 338.5 3177 338.5 3177 338.5 3177 269 3177 259.51 3180.78 249.69 3184.87 241.84 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3186.99 243.06 3188.35 235.77 3182.74 240.62 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3168 403.1 0 46 9 -tumor_bam ", label=tumor_bam, lp="3168,405", pos="e,3189.1,234.46 2705.8,575.52 2718.3,569.2 2735.3,559.97 2749,550 2768.6,535.78 2767.2,523.63 2789,513 2900.3,458.65 2941.3,484.94 \ 3064,468 3079.7,465.83 3123.5,471 3135,460 3156.1,439.75 3131.8,421.07 3145,395 3152.1,380.98 3162.4,383.77 3170,370 3176.9,357.43 \ 3177,352.84 3177,338.5 3177,338.5 3177,338.5 3177,269 3177,259.51 3180.8,249.69 3184.9,241.84"]; tumor_cram_to_bam -> tumor_bam_readcount [_draw_="c 7 -#000000 B 7 2658.5 575.55 2627.19 564.82 2579.36 542.98 2558 505 2543.46 479.14 2550.32 443.19 2556.36 422.48 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2558.69 423.23 2558.45 415.82 2554.01 421.76 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2567.5 493.1 0 19 3 -bam ", label=bam, lp="2567.5,495", pos="e,2558.9,414.37 2658.5,575.55 2627.2,564.82 2579.4,542.98 2558,505 2543.5,479.14 2550.3,443.19 2556.4,422.48"]; normal_bam_readcount -> normal_indel_bam_readcount_tsv [_draw_="c 7 -#000000 B 19 2847.54 395.54 2842.41 393.24 2837.31 390.42 2833 387 2825.75 381.25 2825.26 378.21 2821 370 2798.66 326.97 2787 \ 233.25 2787 226 2787 226 2787 226 2787 134 2787 102.77 2538.88 104.64 2508 100 2494.15 97.92 2479.21 95.38 2465.38 92.91 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2466.19 90.57 2458.87 91.74 2465.32 95.39 ", pos="e,2457.4,91.471 2847.5,395.54 2842.4,393.24 2837.3,390.42 2833,387 2825.8,381.25 2825.3,378.21 2821,370 2798.7,326.97 2787,233.25 \ 2787,226 2787,226 2787,226 2787,134 2787,102.77 2538.9,104.64 2508,100 2494.1,97.918 2479.2,95.384 2465.4,92.914"]; normal_bam_readcount -> normal_snv_bam_readcount_tsv [_draw_="c 7 -#000000 B 19 2854.26 395.62 2849.89 393.25 2845.55 390.38 2842 387 2829.4 375 2809 333.4 2809 316 2809 316 2809 316 2809 224 \ 2809 171.83 2829.27 143.46 2791 108 2782.58 100.2 2699.38 101.49 2688 100 2673.86 98.15 2658.61 95.57 2644.66 92.98 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2645.44 90.63 2638.1 91.74 2644.52 95.45 ", pos="e,2636.6,91.457 2854.3,395.62 2849.9,393.25 2845.5,390.38 2842,387 2829.4,375 2809,333.4 2809,316 2809,316 2809,316 2809,224 2809,\ 171.83 2829.3,143.46 2791,108 2782.6,100.2 2699.4,101.49 2688,100 2673.9,98.15 2658.6,95.57 2644.7,92.979"]; add_normal_bam_readcount_to_vcf [_draw_="c 7 -#000000 C 7 -#f3cea1 P 4 2822 305.5 2822 324.5 3066 324.5 3066 305.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2944 312.5 0 228 46 -Add snv and indel bam-readcount files to a vcf ", fillcolor="#F3CEA1", height=0.27778, label="Add snv and indel bam-readcount files to a vcf", pos="2944,315", rects="2822,305.5,3066,324.5", width=3.3889]; normal_bam_readcount -> add_normal_bam_readcount_to_vcf [_draw_="c 7 -#000000 B 7 2862.49 395.62 2848.01 384.88 2827.53 365.76 2839 350 2846.44 339.77 2857.03 332.55 2868.65 327.48 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2869.37 329.82 2875 324.99 2867.59 325.26 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2888 358.1 0 98 21 -snv_bam_readcount_tsv ", label=snv_bam_readcount_tsv, lp="2888,360", pos="e,2876.4,324.44 2862.5,395.62 2848,384.88 2827.5,365.76 2839,350 2846.4,339.77 2857,332.55 2868.6,327.48"]; normal_bam_readcount -> add_normal_bam_readcount_to_vcf [_draw_="c 7 -#000000 B 7 2899.43 395.62 2911.66 390.18 2925.6 381.87 2934 370 2941.73 359.07 2943.99 343.88 2944.45 332.39 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2946.9 332.66 2944.5 325.64 2942 332.62 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2994 358.1 0 104 23 -indel_bam_readcount_tsv ", label=indel_bam_readcount_tsv, lp="2994,360", pos="e,2944.5,324.13 2899.4,395.62 2911.7,390.18 2925.6,381.87 2934,370 2941.7,359.07 2944,343.88 2944.5,332.39"]; annotated_filter_bgzip [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 3151.5 170.5 3151.5 189.5 3216.5 189.5 3216.5 170.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3184 177.5 0 49 9 -bgzip VCF ", height=0.27778, label="bgzip VCF", pos="3184,180", rects="3151.5,170.5,3216.5,189.5", width=0.90278]; annotated_filter_index [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 3111 125.5 3111 144.5 3173 144.5 3173 125.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3142 132.5 0 46 9 -vcf index ", height=0.27778, label="vcf index", pos="3142,135", rects="3111,125.5,3173,144.5", width=0.86111]; annotated_filter_bgzip -> annotated_filter_index [_draw_="c 7 -#000000 B 4 3175.9 170.71 3170.21 164.88 3162.45 156.93 3155.79 150.12 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3157.77 148.64 3151.13 145.35 3154.27 152.07 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3172.5 155.6 0 13 3 -vcf ", label=vcf, lp="3172.5,157.5", pos="e,3150.1,144.27 3175.9,170.71 3170.2,164.88 3162.4,156.93 3155.8,150.12"]; decompose [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 2579 485.5 2579 504.5 2683 504.5 2683 485.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2631 492.5 0 88 16 -run vt decompose ", height=0.27778, label="run vt decompose", pos="2631,495", rects="2579,485.5,2683,504.5", width=1.4444]; decompose -> annotate_variants [_draw_="c 7 -#000000 B 7 2645.11 485.62 2655.32 479.89 2669.62 472.54 2683 468 2690.63 465.41 2698.76 463.18 2706.9 461.25 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2707.24 463.69 2713.53 459.77 2706.16 458.91 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2689.5 470.6 0 13 3 -vcf ", label=vcf, lp="2689.5,472.5", pos="e,2715,459.44 2645.1,485.62 2655.3,479.89 2669.6,472.54 2683,468 2690.6,465.41 2698.8,463.18 2706.9,461.25"]; mutect -> mutect_unfiltered_vcf [_draw_="c 7 -#000000 B 10 772.57 579.28 820.14 574.04 875 563.19 875 541 875 541 875 541 875 134 875 127.78 946.85 106.76 993.65 93.72 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 994.23 96.1 1000.33 91.87 992.93 91.38 ", pos="e,1001.8,91.468 772.57,579.28 820.14,574.04 875,563.19 875,541 875,541 875,541 875,134 875,127.78 946.85,106.76 993.65,93.724"]; mutect -> mutect_filtered_vcf [_draw_="c 7 -#000000 B 10 772.86 577.68 792.66 571.79 809 560.9 809 541 809 541 809 541 809 134 809 112.41 827.4 99.96 848.65 92.78 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 849.15 95.19 855.13 90.8 847.72 90.5 ", pos="e,856.58,90.364 772.86,577.68 792.66,571.79 809,560.9 809,541 809,541 809,541 809,134 809,112.41 827.4,99.957 848.65,92.778"]; mutect -> combine [_draw_="c 7 -#000000 B 4 772.85 581.13 954.98 573.53 1449.18 552.92 1649.22 544.58 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1649.25 547.03 1656.14 544.29 1649.05 542.13 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1333.5 560.6 0 45 10 -mutect_vcf ", label=mutect_vcf, lp="1333.5,562.5", pos="e,1657.7,544.23 772.85,581.13 954.98,573.53 1449.2,552.92 1649.2,544.58"]; add_vep_fields_to_table -> final_tsv [_draw_="c 7 -#000000 B 7 3036.72 11.76 2944.79 13.78 2798.67 20.84 2750 45 2740.46 49.73 2732.34 58.49 2726.54 66.17 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2724.79 64.41 2722.77 71.55 2728.8 67.23 ", pos="e,2721.9,72.789 3036.7,11.761 2944.8,13.781 2798.7,20.836 2750,45 2740.5,49.734 2732.3,58.485 2726.5,66.173"]; docm -> docm_unfiltered_vcf [_draw_="c 7 -#000000 B 10 1405.8 575.75 1399.38 567.52 1391 554.25 1391 541 1391 541 1391 541 1391 134 1391 122.59 1391 109.75 1391 99.81 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1393.45 99.82 1391 92.82 1388.55 99.82 ", pos="e,1391,91.304 1405.8,575.75 1399.4,567.52 1391,554.25 1391,541 1391,541 1391,541 1391,134 1391,122.59 1391,109.75 1391,99.808"]; docm -> docm_filtered_vcf [_draw_="c 7 -#000000 B 10 1427.15 575.67 1437.95 568.14 1451 555.94 1451 541 1451 541 1451 541 1451 134 1451 117.09 1465.17 104.12 1478.99 \ 95.49 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1479.97 97.76 1484.8 92.14 1477.52 93.52 ", pos="e,1486.1,91.379 1427.1,575.67 1438,568.14 1451,555.94 1451,541 1451,541 1451,541 1451,134 1451,117.09 1465.2,104.12 1479,95.493"]; docm -> combine [_draw_="c 7 -#000000 B 7 1474.26 578.33 1504.35 575.34 1541.13 571.39 1574 567 1608.91 562.34 1647.9 556.07 1678.77 550.86 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1678.86 553.33 1685.35 549.74 1678.04 548.5 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1650.5 560.6 0 39 8 -docm_vcf ", label=docm_vcf, lp="1650.5,562.5", pos="e,1686.8,549.49 1474.3,578.33 1504.4,575.34 1541.1,571.39 1574,567 1608.9,562.34 1647.9,556.07 1678.8,550.86"]; filter_vcf -> annotated_filter_bgzip [_draw_="c 7 -#000000 B 4 3192.88 215.71 3191.54 210.47 3189.76 203.53 3188.15 197.24 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3190.6 196.91 3186.49 190.73 3185.85 198.12 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3196.5 200.6 0 13 4 -file ", label=file, lp="3196.5,202.5", pos="e,3186.1,189.27 3192.9,215.71 3191.5,210.47 3189.8,203.53 3188.2,197.24"]; combine -> decompose [_draw_="c 7 -#000000 B 4 1812.14 536.13 2004.06 528.95 2492.97 510.45 2571.7 505.12 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2571.47 507.6 2578.25 504.6 2571.08 502.71 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2400.5 515.6 0 13 3 -vcf ", label=vcf, lp="2400.5,517.5", pos="e,2579.8,504.48 1812.1,536.13 2004.1,528.95 2493,510.45 2571.7,505.12"]; annotate_variants -> vep_summary [_draw_="c 7 -#000000 B 22 2708.65 440.55 2702.75 438.31 2697.08 435.51 2692 432 2670.24 416.97 2688.17 393.86 2667 378 2648.45 364.1 2580.51 \ 385.19 2563 370 2552.17 360.6 2556 352.84 2556 338.5 2556 338.5 2556 338.5 2556 134 2556 81.45 2373.31 111.33 2322 100 2315.57 98.58 \ 2308.81 96.51 2302.5 94.29 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2303.62 92.09 2296.21 91.97 2301.93 96.69 ", pos="e,2294.8,91.449 2708.7,440.55 2702.7,438.31 2697.1,435.51 2692,432 2670.2,416.97 2688.2,393.86 2667,378 2648.4,364.1 2580.5,385.19 \ 2563,370 2552.2,360.6 2556,352.84 2556,338.5 2556,338.5 2556,338.5 2556,134 2556,81.454 2373.3,111.33 2322,100 2315.6,98.579 2308.8,\ 96.505 2302.5,94.291"]; annotate_variants -> normal_bam_readcount [_draw_="c 7 -#000000 B 4 2791.55 440.5 2807.36 433.97 2829.38 424.86 2846.84 417.64 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2847.56 419.99 2853.1 415.06 2845.69 415.47 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2838.5 425.6 0 13 3 -vcf ", label=vcf, lp="2838.5,427.5", pos="e,2854.5,414.48 2791.5,440.5 2807.4,433.97 2829.4,424.86 2846.8,417.64"]; add_tumor_bam_readcount_to_vcf [_draw_="c 7 -#000000 C 7 -#f3cea1 P 4 2563 350.5 2563 369.5 2807 369.5 2807 350.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2685 357.5 0 228 46 -Add snv and indel bam-readcount files to a vcf ", fillcolor="#F3CEA1", height=0.27778, label="Add snv and indel bam-readcount files to a vcf", pos="2685,360", rects="2563,350.5,2807,369.5", width=3.3889]; annotate_variants -> add_tumor_bam_readcount_to_vcf [_draw_="c 7 -#000000 B 7 2724.62 440.56 2710.24 435.56 2695.85 427.62 2687 415 2679.43 404.21 2679.57 389.01 2681.23 377.48 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2683.63 377.99 2682.5 370.66 2678.81 377.1 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2693.5 403.1 0 13 3 -vcf ", label=vcf, lp="2693.5,405", pos="e,2682.8,369.18 2724.6,440.56 2710.2,435.56 2695.9,427.62 2687,415 2679.4,404.21 2679.6,389.01 2681.2,377.48"]; annotate_variants -> tumor_bam_readcount [_draw_="c 7 -#000000 B 10 2684.77 440.83 2675.21 438.55 2665.77 435.66 2657 432 2650.85 429.43 2651.08 425.74 2645 423 2638.64 420.14 2631.78 \ 417.75 2624.84 415.76 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2625.52 413.41 2618.13 414 2624.27 418.15 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2663.5 425.6 0 13 3 -vcf ", label=vcf, lp="2663.5,427.5", pos="e,2616.7,413.61 2684.8,440.83 2675.2,438.55 2665.8,435.66 2657,432 2650.8,429.43 2651.1,425.74 2645,423 2638.6,420.14 2631.8,417.75 \ 2624.8,415.76"]; index [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 2922 260.5 2922 279.5 2984 279.5 2984 260.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2953 267.5 0 46 9 -vcf index ", height=0.27778, label="vcf index", pos="2953,270", rects="2922,260.5,2984,279.5", width=0.86111]; add_normal_bam_readcount_to_vcf -> index [_draw_="c 7 -#000000 B 4 2945.74 305.71 2946.83 300.47 2948.28 293.53 2949.6 287.24 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2951.92 288.1 2950.96 280.75 2947.13 287.1 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2955.5 290.6 0 13 3 -vcf ", label=vcf, lp="2955.5,292.5", pos="e,2951.3,279.27 2945.7,305.71 2946.8,300.47 2948.3,293.53 2949.6,287.24"]; add_tumor_bam_readcount_to_vcf -> add_normal_bam_readcount_to_vcf [_draw_="c 7 -#000000 B 7 2728.12 350.51 2755.76 345.19 2792.43 338.35 2825 333 2840.52 330.45 2857.22 327.93 2873.05 325.64 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2873.16 328.1 2879.74 324.68 2872.46 323.25 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2831.5 335.6 0 13 3 -vcf ", label=vcf, lp="2831.5,337.5", pos="e,2881.2,324.47 2728.1,350.51 2755.8,345.19 2792.4,338.35 2825,333 2840.5,330.45 2857.2,327.93 2873,325.64"]; tumor_bam_readcount -> tumor_snv_bam_readcount_tsv [_draw_="c 7 -#000000 B 16 2507.08 401.01 2486.85 398.66 2467.32 394.47 2461 387 2458.42 383.95 2459.27 381.61 2461 378 2472.21 354.63 2529.67 \ 318.16 2552 305 2650.9 246.7 2711.8 290.11 2791 207 2820.04 176.53 2830.07 125.68 2833.41 99.57 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2835.81 100.18 2834.16 92.95 2830.94 99.63 ", pos="e,2834.3,91.444 2507.1,401.01 2486.9,398.66 2467.3,394.47 2461,387 2458.4,383.95 2459.3,381.61 2461,378 2472.2,354.63 2529.7,318.16 \ 2552,305 2650.9,246.7 2711.8,290.11 2791,207 2820,176.53 2830.1,125.68 2833.4,99.572"]; tumor_bam_readcount -> tumor_indel_bam_readcount_tsv [_draw_="c 7 -#000000 B 16 2507.08 401.46 2490.62 399.03 2472.98 394.68 2458 387 2443.46 379.54 2432 377.34 2432 361 2432 361 2432 361 2432 \ 134 2432 88.92 2276.39 107.87 2232 100 2219.41 97.77 2205.85 95.3 2193.13 92.95 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2193.72 90.57 2186.39 91.7 2192.82 95.39 ", pos="e,2184.9,91.43 2507.1,401.46 2490.6,399.03 2473,394.68 2458,387 2443.5,379.54 2432,377.34 2432,361 2432,361 2432,361 2432,134 2432,\ 88.918 2276.4,107.87 2232,100 2219.4,97.766 2205.9,95.298 2193.1,92.951"]; tumor_bam_readcount -> add_tumor_bam_readcount_to_vcf [_draw_="c 7 -#000000 B 7 2566.55 395.59 2570.2 389.7 2575.88 382.15 2583 378 2586.64 375.88 2590.47 374 2594.42 372.34 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2595.06 374.72 2600.74 369.95 2593.32 370.14 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2632 380.6 0 98 21 -snv_bam_readcount_tsv ", label=snv_bam_readcount_tsv, lp="2632,382.5", pos="e,2602.2,369.42 2566.6,395.59 2570.2,389.7 2575.9,382.15 2583,378 2586.6,375.88 2590.5,374 2594.4,372.34"]; tumor_bam_readcount -> add_tumor_bam_readcount_to_vcf [_draw_="c 7 -#000000 B 7 2507.24 403.37 2478.2 401.16 2451.44 394.82 2467 378 2473.81 370.64 2512.15 366.46 2554.83 364.08 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2554.76 366.54 2561.62 363.73 2554.5 361.65 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2519 380.6 0 104 23 -indel_bam_readcount_tsv ", label=indel_bam_readcount_tsv, lp="2519,382.5", pos="e,2563.1,363.65 2507.2,403.37 2478.2,401.16 2451.4,394.82 2467,378 2473.8,370.64 2512.2,366.46 2554.8,364.08"]; strelka -> strelka_filtered_vcf [_draw_="c 7 -#000000 B 10 1650 575.76 1650 567.1 1650 553.09 1650 541 1650 541 1650 541 1650 134 1650 120.1 1682.54 104.69 1708.92 94.49 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1709.76 96.79 1715.44 92.03 1708.03 92.21 ", pos="e,1716.9,91.498 1650,575.76 1650,567.1 1650,553.09 1650,541 1650,541 1650,541 1650,134 1650,120.1 1682.5,104.69 1708.9,94.49"]; strelka -> strelka_unfiltered_vcf [_draw_="c 7 -#000000 B 10 1645.57 575.69 1641.47 567.22 1636 553.56 1636 541 1636 541 1636 541 1636 134 1636 122.07 1632.39 109.11 1628.84 \ 99.24 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1631.19 98.52 1626.37 92.88 1626.62 100.29 ", pos="e,1625.8,91.468 1645.6,575.69 1641.5,567.22 1636,553.56 1636,541 1636,541 1636,541 1636,134 1636,122.07 1632.4,109.11 1628.8,99.242"]; strelka -> combine [_draw_="c 7 -#000000 B 4 1666.79 575.5 1679.37 569.14 1696.75 560.35 1710.82 553.23 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1711.75 555.51 1716.89 550.16 1709.54 551.13 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1722 560.6 0 44 11 -strelka_vcf ", label=strelka_vcf, lp="1722,562.5", pos="e,1718.2,549.48 1666.8,575.5 1679.4,569.14 1696.7,560.35 1710.8,553.23"]; pindel -> pindel_unfiltered_vcf [_draw_="c 7 -#000000 B 10 1232.53 575.52 1234.88 566.91 1238 553.15 1238 541 1238 541 1238 541 1238 134 1238 120.33 1246.24 107.2 1254.22 \ 97.69 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1255.97 99.4 1258.85 92.56 1252.34 96.11 ", pos="e,1259.9,91.442 1232.5,575.52 1234.9,566.91 1238,553.15 1238,541 1238,541 1238,541 1238,134 1238,120.33 1246.2,107.2 1254.2,97.685"]; pindel -> pindel_filtered_vcf [_draw_="c 7 -#000000 B 10 1228.47 575.79 1227 567.16 1225 553.18 1225 541 1225 541 1225 541 1225 134 1225 114.93 1208.05 102.39 1190.48 \ 94.52 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1191.76 92.4 1184.36 92.01 1189.9 96.94 ", pos="e,1183,91.432 1228.5,575.79 1227,567.16 1225,553.18 1225,541 1225,541 1225,541 1225,134 1225,114.93 1208,102.39 1190.5,94.524"]; pindel -> combine [_draw_="c 7 -#000000 B 13 1296.94 578.68 1314.22 577.39 1332.8 576.07 1350 575 1385.53 572.78 1475.32 575.03 1510 567 1519.89 564.71 1521.15 \ 560.45 1531 558 1569.15 548.5 1612.43 544.04 1649.28 542.03 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1649.14 544.49 1656.01 541.69 1648.89 539.6 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1552 560.6 0 42 10 -pindel_vcf ", label=pindel_vcf, lp="1552,562.5", pos="e,1657.5,541.62 1296.9,578.68 1314.2,577.39 1332.8,576.07 1350,575 1385.5,572.78 1475.3,575.03 1510,567 1519.9,564.71 1521.1,560.45 \ 1531,558 1569.2,548.5 1612.4,544.04 1649.3,542.03"]; index -> final_vcf [_draw_="c 7 -#000000 B 10 2953 260.76 2953 252.1 2953 238.09 2953 226 2953 226 2953 226 2953 134 2953 122.59 2953 109.75 2953 99.81 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2955.45 99.82 2953 92.82 2950.55 99.82 ", pos="e,2953,91.304 2953,260.76 2953,252.1 2953,238.09 2953,226 2953,226 2953,226 2953,134 2953,122.59 2953,109.75 2953,99.808"]; index -> filter_vcf [_draw_="c 7 -#000000 B 4 2983.65 263.55 3022.72 256.61 3091 244.48 3139.37 235.88 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3139.6 238.33 3146.07 234.69 3138.75 233.51 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3101.5 245.6 0 13 3 -vcf ", label=vcf, lp="3101.5,247.5", pos="e,3147.6,234.43 2983.6,263.55 3022.7,256.61 3091,244.48 3139.4,235.88"]; normal_cram_to_bam -> normal_bam_readcount [_draw_="c 7 -#000000 B 13 2503.45 575.61 2502.69 556.44 2503.75 509.22 2530 485 2576.45 442.13 2616.73 494.02 2670 460 2679.14 454.16 2674.85 \ 445.84 2684 440 2689.55 436.46 2759.67 424.54 2813.35 415.81 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2813.47 418.28 2819.98 414.74 2812.68 413.44 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2539.5 493.1 0 19 3 -bam ", label=bam, lp="2539.5,495", pos="e,2821.5,414.5 2503.4,575.61 2502.7,556.44 2503.8,509.22 2530,485 2576.4,442.13 2616.7,494.02 2670,460 2679.1,454.16 2674.9,445.84 \ 2684,440 2689.6,436.46 2759.7,424.54 2813.4,415.81"]; varscan -> varscan_unfiltered_vcf [_draw_="c 7 -#000000 B 10 1972.53 575.79 1974 567.16 1976 553.18 1976 541 1976 541 1976 541 1976 134 1976 122.33 1978.07 109.35 1980.1 99.4 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1982.46 100.08 1981.57 92.72 1977.67 99.03 ", pos="e,1981.9,91.241 1972.5,575.79 1974,567.16 1976,553.18 1976,541 1976,541 1976,541 1976,134 1976,122.33 1978.1,109.35 1980.1,99.399"]; varscan -> varscan_filtered_vcf [_draw_="c 7 -#000000 B 10 1940.24 575.51 1924.25 569.03 1908 558.22 1908 541 1908 541 1908 541 1908 134 1908 117.84 1895.05 104.81 1882.46 \ 95.97 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1884.06 94.09 1876.86 92.32 1881.39 98.2 ", pos="e,1875.6,91.498 1940.2,575.51 1924.2,569.03 1908,558.22 1908,541 1908,541 1908,541 1908,134 1908,117.84 1895,104.81 1882.5,95.973"]; varscan -> combine [_draw_="c 7 -#000000 B 7 1919.77 577.26 1899.54 574.39 1876.13 570.83 1855 567 1829.78 562.43 1801.78 556.41 1779.18 551.32 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1779.95 548.99 1772.58 549.83 1778.87 553.76 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1879.5 560.6 0 49 11 -varscan_vcf ", label=varscan_vcf, lp="1879.5,562.5", pos="e,1771.1,549.49 1919.8,577.26 1899.5,574.39 1876.1,570.83 1855,567 1829.8,562.43 1801.8,556.41 1779.2,551.32"]; variants_to_table -> add_vep_fields_to_table [_draw_="c 7 -#000000 B 4 3331.33 72.56 3286.63 59.84 3202.05 35.77 3152.93 21.79 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3153.64 19.45 3146.23 19.89 3152.3 24.16 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3207.5 30.6 0 13 3 -tsv ", label=tsv, lp="3207.5,32.5", pos="e,3144.8,19.474 3331.3,72.556 3286.6,59.838 3202,35.769 3152.9,21.794"]; annotated_filter_index -> final_filtered_vcf [_draw_="c 7 -#000000 B 4 3124.33 125.58 3106.83 117.24 3079.86 104.38 3060.13 94.98 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3061.43 92.89 3054.06 92.09 3059.33 97.31 ", pos="e,3052.7,91.434 3124.3,125.58 3106.8,117.24 3079.9,104.38 3060.1,94.978"]; annotated_filter_index -> add_vep_fields_to_table [_draw_="c 7 -#000000 B 4 3140.14 125.55 3135.71 105.35 3124.44 54 3118.61 27.45 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3121.02 26.98 3117.12 20.67 3116.23 28.03 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3140.5 80.1 0 13 3 -vcf ", label=vcf, lp="3140.5,82", pos="e,3116.8,19.19 3140.1,125.55 3135.7,105.35 3124.4,54.002 3118.6,27.454"]; annotated_filter_index -> variants_to_table [_draw_="c 7 -#000000 B 4 3172.91 126.8 3210.38 118.07 3273.81 103.31 3316.53 93.36 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3317.04 95.75 3323.31 91.78 3315.93 90.98 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3257.5 110.6 0 13 3 -vcf ", label=vcf, lp="3257.5,112.5", pos="e,3324.8,91.435 3172.9,126.8 3210.4,118.07 3273.8,103.31 3316.5,93.357"]; default1 [_draw_="c 7 -#000000 C 7 -#d5aefc P 4 3067 440.5 3067 459.5 3135 459.5 3135 440.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3101 447.5 0 52 8 -\"NORMAL\" ", fillcolor="#D5AEFC", height=0.27778, label="\"NORMAL\"", pos="3101,450", rects="3067,440.5,3135,459.5", width=0.94444]; default1 -> normal_bam_readcount [_draw_="c 7 -#000000 B 7 3092.05 440.66 3085 434.63 3074.62 426.89 3064 423 3041.58 414.79 2983.94 410.42 2938.16 408.18 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2938.38 405.74 2931.27 407.86 2938.15 410.64 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3095.5 425.6 0 31 6 -sample ", label=sample, lp="3095.5,427.5", pos="e,2929.8,407.79 3092,440.66 3085,434.63 3074.6,426.89 3064,423 3041.6,414.79 2983.9,410.42 2938.2,408.18"]; default2 [_draw_="c 7 -#000000 C 7 -#d5aefc P 4 3050 350.5 3050 369.5 3118 369.5 3118 350.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3084 357.5 0 52 8 -\"NORMAL\" ", fillcolor="#D5AEFC", height=0.27778, label="\"NORMAL\"", pos="3084,360", rects="3050,350.5,3118,369.5", width=0.94444]; default2 -> add_normal_bam_readcount_to_vcf [_draw_="c 7 -#000000 B 4 3056.34 350.5 3034.39 343.76 3003.53 334.28 2979.71 326.97 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2980.46 324.64 2973.05 324.92 2979.02 329.32 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3055 335.6 0 58 11 -sample_name ", label=sample_name, lp="3055,337.5", pos="e,2971.6,324.48 3056.3,350.5 3034.4,343.76 3003.5,334.28 2979.7,326.97"]; default3 [_draw_="c 7 -#000000 C 7 -#d5aefc P 4 3122.5 350.5 3122.5 369.5 3169.5 369.5 3169.5 350.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3146 357.5 0 31 5 -\"DNA\" ", fillcolor="#D5AEFC", height=0.27778, label="\"DNA\"", pos="3146,360", rects="3122.5,350.5,3169.5,369.5", width=0.65278]; default3 -> add_normal_bam_readcount_to_vcf [_draw_="c 7 -#000000 B 7 3129.62 350.51 3117.59 344.66 3100.68 337.2 3085 333 3074.36 330.15 3063.15 327.78 3051.87 325.81 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3052.47 323.42 3045.16 324.69 3051.66 328.26 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3130.5 335.6 0 41 9 -data_type ", label=data_type, lp="3130.5,337.5", pos="e,3043.7,324.44 3129.6,350.51 3117.6,344.66 3100.7,337.2 3085,333 3074.4,330.15 3063.1,327.78 3051.9,325.81"]; default4 [_draw_="c 7 -#000000 C 7 -#d5aefc P 4 2702 395.5 2702 414.5 2764 414.5 2764 395.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2733 402.5 0 46 7 -\"TUMOR\" ", fillcolor="#D5AEFC", height=0.27778, label="\"TUMOR\"", pos="2733,405", rects="2702,395.5,2764,414.5", width=0.86111]; default4 -> add_tumor_bam_readcount_to_vcf [_draw_="c 7 -#000000 B 7 2714.3 395.67 2709.98 393.25 2705.6 390.34 2702 387 2698.8 384.04 2695.93 380.36 2693.5 376.71 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2695.65 375.53 2689.94 370.8 2691.45 378.06 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2731 380.6 0 58 11 -sample_name ", label=sample_name, lp="2731,382.5", pos="e,2689.2,369.5 2714.3,395.67 2710,393.25 2705.6,390.34 2702,387 2698.8,384.04 2695.9,380.36 2693.5,376.71"]; default5 [_draw_="c 7 -#000000 C 7 -#d5aefc P 4 2768.5 395.5 2768.5 414.5 2815.5 414.5 2815.5 395.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2792 402.5 0 31 5 -\"DNA\" ", fillcolor="#D5AEFC", height=0.27778, label="\"DNA\"", pos="2792,405", rects="2768.5,395.5,2815.5,414.5", width=0.65278]; default5 -> add_tumor_bam_readcount_to_vcf [_draw_="c 7 -#000000 B 10 2780.76 395.71 2777.01 392.95 2772.82 389.85 2769 387 2763.65 383.02 2763.04 380.83 2757 378 2752 375.66 2746.64 \ 373.63 2741.2 371.86 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2742.04 369.56 2734.64 369.9 2740.64 374.25 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2789.5 380.6 0 41 9 -data_type ", label=data_type, lp="2789.5,382.5", pos="e,2733.2,369.46 2780.8,395.71 2777,392.95 2772.8,389.85 2769,387 2763.7,383.02 2763,380.83 2757,378 2752,375.66 2746.6,373.63 2741.2,\ 371.86"]; default6 [_draw_="c 7 -#000000 C 7 -#d5aefc P 4 2608 440.5 2608 459.5 2670 459.5 2670 440.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2639 447.5 0 46 7 -\"TUMOR\" ", fillcolor="#D5AEFC", height=0.27778, label="\"TUMOR\"", pos="2639,450", rects="2608,440.5,2670,459.5", width=0.86111]; default6 -> tumor_bam_readcount [_draw_="c 7 -#000000 B 7 2628.07 440.52 2618.61 433.21 2606.26 423.71 2605 423 2601.6 421.08 2597.93 419.27 2594.23 417.6 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2595.44 415.46 2588.04 414.98 2593.53 419.97 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2631.5 425.6 0 31 6 -sample ", label=sample, lp="2631.5,427.5", pos="e,2586.6,414.39 2628.1,440.52 2618.6,433.21 2606.3,423.71 2605,423 2601.6,421.08 2597.9,419.27 2594.2,417.6"]; }