digraph workflow {
	graph [_draw_="c 9 -#fffffe00 C 7 -#eeeeee P 4 0 0 0 368 1209 368 1209 0 ",
		bb="0,0,1209,368",
		bgcolor="#eeeeee",
		clusterrank=local,
		color=black,
		dpi=96,
		fontsize=10,
		labeljust=left,
		nodesep=0.05,
		ranksep=0.22,
		xdotversion=1.7
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	node [color=black,
		fillcolor=lightgoldenrodyellow,
		fontcolor=black,
		fontname=Helvetica,
		fontsize=10,
		height=0,
		label="\N",
		shape=record,
		style=filled,
		width=0
	];
	edge [arrowsize=0.7,
		color=black,
		fontcolor=black,
		fontname=Helvetica,
		fontsize=8
	];
	subgraph cluster_inputs {
		graph [_draw_="S 6 -dashed c 7 -#000000 C 7 -#eeeeee P 4 8 305 8 360 1201 360 1201 305 ",
			_ldraw_="F 10 11 -Times-Roman c 7 -#000000 T 58 348 0 84 15 -Workflow Inputs ",
			bb="8,305,1201,360",
			label="Workflow Inputs",
			lheight=0.15,
			lp="58,350.5",
			lwidth=1.17,
			rank=same,
			style=dashed
		];
		cosmic_vcf	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 93.5 313.5 93.5 332.5 164.5 332.5 164.5 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 129 320.5 0 55 10 -cosmic_vcf ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=cosmic_vcf,
			pos="129,323",
			rects="93.5,313.5,164.5,332.5",
			width=0.98611];
		tumor_bam	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 16.5 313.5 16.5 332.5 89.5 332.5 89.5 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 53 320.5 0 57 9 -tumor_bam ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=tumor_bam,
			pos="53,323",
			rects="16.5,313.5,89.5,332.5",
			width=1.0139];
		normal_bam	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 297 313.5 297 332.5 375 332.5 375 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 336 320.5 0 62 10 -normal_bam ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=normal_bam,
			pos="336,323",
			rects="297,313.5,375,332.5",
			width=1.0833];
		max_alt_alleles_in_normal_count	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 519 313.5 519 332.5 699 332.5 699 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 609 320.5 0 164 31 -max_alt_alleles_in_normal_count ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=max_alt_alleles_in_normal_count,
			pos="609,323",
			rects="519,313.5,699,332.5",
			width=2.5];
		interval_list	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 791 313.5 791 332.5 865 332.5 865 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 828 320.5 0 58 13 -interval_list ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=interval_list,
			pos="828,323",
			rects="791,313.5,865,332.5",
			width=1.0278];
		dbsnp_vcf	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 937 313.5 937 332.5 1003 332.5 1003 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 970 320.5 0 50 9 -dbsnp_vcf ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=dbsnp_vcf,
			pos="970,323",
			rects="937,313.5,1003,332.5",
			width=0.91667];
		max_alt_allele_in_normal_fraction	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 1007.5 313.5 1007.5 332.5 1192.5 332.5 1192.5 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1100 320.5 0 169 33 -max_alt_allele_in_normal_fraction ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=max_alt_allele_in_normal_fraction,
			pos="1100,323",
			rects="1007.5,313.5,1192.5,332.5",
			width=2.5694];
		reference	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 869.5 313.5 869.5 332.5 932.5 332.5 932.5 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 901 320.5 0 47 9 -reference ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=reference,
			pos="901,323",
			rects="869.5,313.5,932.5,332.5",
			width=0.875];
		panel_of_normals_vcf	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 169 313.5 169 332.5 293 332.5 293 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 231 320.5 0 108 20 -panel_of_normals_vcf ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=panel_of_normals_vcf,
			pos="231,323",
			rects="169,313.5,293,332.5",
			width=1.7222];
		artifact_detection_mode	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 379 313.5 379 332.5 515 332.5 515 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 447 320.5 0 120 23 -artifact_detection_mode ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=artifact_detection_mode,
			pos="447,323",
			rects="379,313.5,515,332.5",
			width=1.8889];
		scatter_count	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 703.5 313.5 703.5 332.5 786.5 332.5 786.5 313.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 745 320.5 0 67 13 -scatter_count ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=scatter_count,
			pos="745,323",
			rects="703.5,313.5,786.5,332.5",
			width=1.1528];
	}
	subgraph cluster_outputs {
		graph [_draw_="S 6 -dashed c 7 -#000000 C 7 -#eeeeee P 4 393 8 393 63 568 63 568 8 ",
			_ldraw_="F 10 11 -Times-Roman c 7 -#000000 T 447 15 0 92 16 -Workflow Outputs ",
			bb="393,8,568,63",
			label="Workflow Outputs",
			labelloc=b,
			lheight=0.15,
			lp="447,17.5",
			lwidth=1.28,
			rank=same,
			style=dashed
		];
		unfiltered_vcf	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 401.5 35.5 401.5 54.5 484.5 54.5 484.5 35.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 443 42.5 0 67 14 -unfiltered_vcf ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=unfiltered_vcf,
			pos="443,45",
			rects="401.5,35.5,484.5,54.5",
			width=1.1528];
		filtered_vcf	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 488.5 35.5 488.5 54.5 559.5 54.5 559.5 35.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 524 42.5 0 55 12 -filtered_vcf ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=filtered_vcf,
			pos="524,45",
			rects="488.5,35.5,559.5,54.5",
			width=0.98611];
	}
	mutect	[_draw_="c 7 -#000000 C 7 -#fafad2 P 4 445 215.5 445 234.5 557 234.5 557 215.5 ",
		_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 501 222.5 0 96 18 -mutect2 (GATK 3.6) ",
		height=0.27778,
		label="mutect2 (GATK 3.6)",
		pos="501,225",
		rects="445,215.5,557,234.5",
		width=1.5556];
	cosmic_vcf -> mutect	[_draw_="c 7 -#000000 B 7 137.11 313.65 150.8 300.09 179.94 273.46 210 260 249.28 242.41 363.79 233.22 436.9 229.01 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 436.8 231.47 443.66 228.63 436.53 226.58 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 232.5 268.1 0 45 10 -cosmic_vcf ",
		label=cosmic_vcf,
		lp="232.5,270",
		pos="e,445.17,228.54 137.11,313.65 150.8,300.09 179.94,273.46 210,260 249.28,242.41 363.79,233.22 436.9,229.01"];
	filter	[_draw_="c 7 -#000000 C 7 -#f3cea1 P 4 450.5 80.5 450.5 99.5 551.5 99.5 551.5 80.5 ",
		_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 501 87.5 0 85 18 -fp_filter workflow ",
		fillcolor="#F3CEA1",
		height=0.27778,
		label="fp_filter workflow",
		pos="501,90",
		rects="450.5,80.5,551.5,99.5",
		width=1.4028];
	tumor_bam -> filter	[_draw_="c 7 -#000000 B 10 54.05 313.71 55.24 303.63 57 286.1 57 271 57 271 57 271 57 134 57 95.71 321.94 90.92 442.51 90.72 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 442.42 93.17 449.42 90.71 442.42 88.27 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 66.5 200.6 0 19 3 -bam ",
		label=bam,
		lp="66.5,202.5",
		pos="e,450.93,90.712 54.051,313.71 55.236,303.63 57,286.1 57,271 57,271 57,271 57,134 57,95.713 321.94,90.919 442.51,90.719"];
	tumor_bam -> mutect	[_draw_="c 7 -#000000 B 7 60.46 313.54 73.08 299.83 100.11 272.98 129 260 182.35 236.02 345.19 228.95 436.75 226.87 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 436.65 229.32 443.6 226.72 436.54 224.42 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 152 268.1 0 46 9 -tumor_bam ",
		label=tumor_bam,
		lp="152,270",
		pos="e,445.11,226.69 60.46,313.54 73.082,299.83 100.11,272.98 129,260 182.35,236.02 345.19,228.95 436.75,226.87"];
	normal_bam -> mutect	[_draw_="c 7 -#000000 B 7 341.04 313.88 349.66 300.66 368.5 274.5 391 260 407.69 249.25 427.98 241.72 446.57 236.53 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 446.82 239 452.96 234.84 445.56 234.27 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 416.5 268.1 0 51 10 -normal_bam ",
		label=normal_bam,
		lp="416.5,270",
		pos="e,454.42,234.45 341.04,313.88 349.66,300.66 368.5,274.5 391,260 407.69,249.25 427.98,241.72 446.57,236.53"];
	max_alt_alleles_in_normal_count -> mutect	[_draw_="c 7 -#000000 B 10 596.53 313.79 585.44 306.03 569.28 293.6 558 280 551.52 272.19 553.68 267.64 547 260 540.02 252.02 530.87 244.79 \
522.56 239.06 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 524.01 237.08 516.82 235.27 521.31 241.17 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 624.5 268.1 0 133 31 -max_alt_alleles_in_normal_count ",
		label=max_alt_alleles_in_normal_count,
		lp="624.5,270",
		pos="e,515.56,234.44 596.53,313.79 585.44,306.03 569.28,293.6 558,280 551.52,272.19 553.68,267.64 547,260 540.02,252.02 530.87,244.79 \
522.56,239.06"];
	split_interval_list	[_draw_="c 7 -#000000 C 7 -#fafad2 P 4 692.5 260.5 692.5 279.5 793.5 279.5 793.5 260.5 ",
		_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 743 267.5 0 85 19 -split_interval_list ",
		height=0.27778,
		label=split_interval_list,
		pos="743,270",
		rects="692.5,260.5,793.5,279.5",
		width=1.4028];
	interval_list -> split_interval_list	[_draw_="c 7 -#000000 B 10 811.05 313.55 802.22 308.95 791.33 302.99 782 297 776.39 293.4 775.49 291.78 770 288 768.03 286.65 765.96 285.27 \
763.88 283.91 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 765.37 281.95 758.15 280.25 762.73 286.08 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 805.5 290.6 0 47 13 -interval_list ",
		label=interval_list,
		lp="805.5,292.5",
		pos="e,756.88,279.43 811.05,313.55 802.22,308.95 791.33,302.99 782,297 776.39,293.4 775.49,291.78 770,288 768.03,286.65 765.96,285.27 \
763.88,283.91"];
	dbsnp_vcf -> mutect	[_draw_="c 7 -#000000 B 7 960.32 313.69 943.7 299.95 908.14 272.74 873 260 818.09 240.09 656.28 231.36 565.19 227.94 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 565.47 225.5 558.38 227.69 565.29 230.4 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 933 268.1 0 42 9 -dbsnp_vcf ",
		label=dbsnp_vcf,
		lp="933,270",
		pos="e,556.87,227.64 960.32,313.69 943.7,299.95 908.14,272.74 873,260 818.09,240.09 656.28,231.36 565.19,227.94"];
	max_alt_allele_in_normal_fraction -> mutect	[_draw_="c 7 -#000000 B 7 1084.43 313.6 1058.44 299.97 1004.17 273.23 955 260 883.38 240.73 672.79 231.44 565.46 227.85 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 565.57 225.41 558.49 227.63 565.4 230.3 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1079.5 268.1 0 137 33 -max_alt_allele_in_normal_fraction ",
		label=max_alt_allele_in_normal_fraction,
		lp="1079.5,270",
		pos="e,556.98,227.58 1084.4,313.6 1058.4,299.97 1004.2,273.23 955,260 883.38,240.73 672.79,231.44 565.46,227.85"];
	reference -> filter	[_draw_="c 7 -#000000 B 10 909.23 313.79 917.81 304.33 930 287.91 930 271 930 271 930 271 930 134 930 97.22 677.16 91.57 559.69 90.93 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 560 88.48 552.99 90.9 559.98 93.38 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 950 200.6 0 40 9 -reference ",
		label=reference,
		lp="950,202.5",
		pos="e,551.47,90.891 909.23,313.79 917.81,304.33 930,287.91 930,271 930,271 930,271 930,134 930,97.223 677.16,91.571 559.69,90.929"];
	reference -> mutect	[_draw_="c 7 -#000000 B 7 888.18 313.61 864.62 298.33 815.11 266.91 796 260 754.92 245.15 638.95 235.06 565.25 229.94 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 565.58 227.5 558.43 229.47 565.25 232.39 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 852 268.1 0 40 9 -reference ",
		label=reference,
		lp="852,270",
		pos="e,556.92,229.37 888.18,313.61 864.62,298.33 815.11,266.91 796,260 754.92,245.15 638.95,235.06 565.25,229.94"];
	panel_of_normals_vcf -> mutect	[_draw_="c 7 -#000000 B 7 234.91 313.51 241.73 299.75 257.18 272.84 279 260 305.05 244.67 380.97 235.44 436.81 230.54 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 436.96 232.99 443.73 229.95 436.54 228.1 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 323 268.1 0 88 20 -panel_of_normals_vcf ",
		label=panel_of_normals_vcf,
		lp="323,270",
		pos="e,445.24,229.82 234.91,313.51 241.73,299.75 257.18,272.84 279,260 305.05,244.67 380.97,235.44 436.81,230.54"];
	artifact_detection_mode -> mutect	[_draw_="c 7 -#000000 B 7 445.18 313.73 442.89 301.2 440.33 277.06 450 260 455.16 250.89 463.9 243.75 472.69 238.43 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 473.75 240.64 478.69 235.11 471.38 236.35 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 500 268.1 0 100 23 -artifact_detection_mode ",
		label=artifact_detection_mode,
		lp="500,270",
		pos="e,480.02,234.37 445.18,313.73 442.89,301.2 440.33,277.06 450,260 455.16,250.89 463.9,243.75 472.69,238.43"];
	scatter_count -> split_interval_list	[_draw_="c 7 -#000000 B 10 731.51 313.72 725.92 309.48 720.04 303.78 717 297 715.37 293.35 715.1 291.52 717 288 717.52 287.04 718.12 286.12 \
718.78 285.25 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 720.42 287.08 723.78 280.48 717.03 283.54 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 745 290.6 0 56 13 -scatter_count ",
		label=scatter_count,
		lp="745,292.5",
		pos="e,724.88,279.43 731.51,313.72 725.92,309.48 720.04,303.78 717,297 715.37,293.35 715.1,291.52 717,288 717.52,287.04 718.12,286.12 \
718.78,285.25"];
	merge	[_draw_="c 7 -#000000 C 7 -#fafad2 P 4 468 170.5 468 189.5 534 189.5 534 170.5 ",
		_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 501 177.5 0 50 9 -vcf merge ",
		height=0.27778,
		label="vcf merge",
		pos="501,180",
		rects="468,170.5,534,189.5",
		width=0.91667];
	index	[_draw_="c 7 -#000000 C 7 -#fafad2 P 4 470 125.5 470 144.5 532 144.5 532 125.5 ",
		_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 501 132.5 0 46 9 -vcf index ",
		height=0.27778,
		label="vcf index",
		pos="501,135",
		rects="470,125.5,532,144.5",
		width=0.86111];
	merge -> index	[_draw_="c 7 -#000000 B 4 501 170.71 501 165.59 501 158.85 501 152.67 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 503.45 152.78 501 145.78 498.55 152.78 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 507.5 155.6 0 13 3 -vcf ",
		label=vcf,
		lp="507.5,157.5",
		pos="e,501,144.27 501,170.71 501,165.59 501,158.85 501,152.67"];
	filter -> unfiltered_vcf	[_draw_="c 7 -#000000 B 4 489.54 80.5 481.44 74.5 470.41 66.32 461.12 59.43 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 462.73 57.58 455.65 55.38 459.82 61.52 ",
		pos="e,454.44,54.478 489.54,80.505 481.44,74.497 470.41,66.32 461.12,59.435"];
	filter -> filtered_vcf	[_draw_="c 7 -#000000 B 4 505.43 80.71 508.36 75.24 512.29 67.9 515.77 61.38 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 517.72 62.93 518.87 55.6 513.4 60.62 ",
		pos="e,519.58,54.265 505.43,80.709 508.36,75.236 512.29,67.899 515.77,61.381"];
	mutect -> merge	[_draw_="c 7 -#000000 B 4 501 215.71 501 210.59 501 203.85 501 197.67 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 503.45 197.78 501 190.78 498.55 197.78 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 509.5 200.6 0 17 4 -vcfs ",
		label=vcfs,
		lp="509.5,202.5",
		pos="e,501,189.27 501,215.71 501,210.59 501,203.85 501,197.67"];
	split_interval_list -> mutect	[_draw_="c 7 -#000000 B 4 695.19 260.5 655.41 253.44 598.74 243.37 556.88 235.93 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 557.52 233.56 550.2 234.74 556.67 238.38 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 666.5 245.6 0 47 13 -interval_list ",
		label=interval_list,
		lp="666.5,247.5",
		pos="e,548.71,234.48 695.19,260.5 655.41,253.44 598.74,243.37 556.88,235.93"];
	index -> filter	[_draw_="c 7 -#000000 B 4 501 125.71 501 120.59 501 113.85 501 107.67 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 503.45 107.78 501 100.78 498.55 107.78 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 507.5 110.6 0 13 3 -vcf ",
		label=vcf,
		lp="507.5,112.5",
		pos="e,501,99.265 501,125.71 501,120.59 501,113.85 501,107.67"];
}