digraph workflow { graph [_draw_="c 9 -#fffffe00 C 7 -#eeeeee P 4 0 0 0 241 10829.5 241 10829.5 0 ", bb="0,0,10830,241", bgcolor="#eeeeee", clusterrank=local, color=black, dpi=96, fontsize=10, labeljust=left, nodesep=0.05, ranksep=0.22, xdotversion=1.7 ]; node [color=black, fillcolor=lightgoldenrodyellow, fontcolor=black, fontname=Helvetica, fontsize=10, height=0, label="\N", shape=record, style=filled, width=0 ]; edge [arrowsize=0.7, color=black, fontcolor=black, fontname=Helvetica, fontsize=8 ]; subgraph cluster_outputs { graph [_draw_="S 6 -dashed c 7 -#000000 C 7 -#eeeeee P 4 2123 8 2123 63 10579 63 10579 8 ", _ldraw_="F 10 11 -Times-Roman c 7 -#000000 T 2177 15 0 92 16 -Workflow Outputs ", bb="2123,8,10579,63", label="Workflow Outputs", labelloc=b, lheight=0.15, lp="2177,17.5", lwidth=1.28, rank=same, style=dashed ]; cn_scatter_plot [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 9376.5 35.5 9376.5 54.5 9467.5 54.5 9467.5 35.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 9422 42.5 0 75 15 -cn_scatter_plot ", fillcolor="#94DDF4", height=0.27778, label=cn_scatter_plot, pos="9422,45", rects="9376.5,35.5,9467.5,54.5", width=1.2639]; 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normal_mark_duplicates_metrics [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 7036.5 35.5 7036.5 54.5 7215.5 54.5 7215.5 35.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 7126 42.5 0 163 30 -normal_mark_duplicates_metrics ", fillcolor="#94DDF4", height=0.27778, label=normal_mark_duplicates_metrics, pos="7126,45", rects="7036.5,35.5,7215.5,54.5", width=2.4861]; normal_alignment_summary_metrics [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 7220 35.5 7220 54.5 7420 54.5 7420 35.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 7320 42.5 0 184 32 -normal_alignment_summary_metrics ", fillcolor="#94DDF4", height=0.27778, label=normal_alignment_summary_metrics, pos="7320,45", rects="7220,35.5,7420,54.5", width=2.7778]; mutect_unfiltered_vcf [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 3690.5 35.5 3690.5 54.5 3813.5 54.5 3813.5 35.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3752 42.5 0 107 21 -mutect_unfiltered_vcf ", fillcolor="#94DDF4", height=0.27778, label=mutect_unfiltered_vcf, pos="3752,45", rects="3690.5,35.5,3813.5,54.5", width=1.7083]; normal_antitarget_coverage [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 8377.5 35.5 8377.5 54.5 8532.5 54.5 8532.5 35.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 8455 42.5 0 139 26 -normal_antitarget_coverage ", fillcolor="#94DDF4", height=0.27778, label=normal_antitarget_coverage, pos="8455,45", rects="8377.5,35.5,8532.5,54.5", width=2.1528]; tumor_mark_duplicates_metrics [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 4705 35.5 4705 54.5 4879 54.5 4879 35.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 4792 42.5 0 158 29 -tumor_mark_duplicates_metrics ", fillcolor="#94DDF4", height=0.27778, label=tumor_mark_duplicates_metrics, pos="4792,45", rects="4705,35.5,4879,54.5", width=2.4167]; varscan_filtered_vcf [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 3817.5 35.5 3817.5 54.5 3932.5 54.5 3932.5 35.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3875 42.5 0 99 20 -varscan_filtered_vcf ", fillcolor="#94DDF4", height=0.27778, label=varscan_filtered_vcf, pos="3875,45", rects="3817.5,35.5,3932.5,54.5", width=1.5972]; reference_coverage [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 8536.5 35.5 8536.5 54.5 8649.5 54.5 8649.5 35.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 8593 42.5 0 97 18 -reference_coverage ", fillcolor="#94DDF4", height=0.27778, label=reference_coverage, pos="8593,45", rects="8536.5,35.5,8649.5,54.5", width=1.5694]; tumor_target_coverage [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 8653.5 35.5 8653.5 54.5 8784.5 54.5 8784.5 35.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 8719 42.5 0 115 21 -tumor_target_coverage ", fillcolor="#94DDF4", height=0.27778, label=tumor_target_coverage, pos="8719,45", rects="8653.5,35.5,8784.5,54.5", width=1.8194]; tumor_alignment_summary_metrics [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 4883 35.5 4883 54.5 5077 54.5 5077 35.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 4980 42.5 0 178 31 -tumor_alignment_summary_metrics ", fillcolor="#94DDF4", height=0.27778, label=tumor_alignment_summary_metrics, pos="4980,45", rects="4883,35.5,5077,54.5", width=2.6944]; final_tsv [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 3937 35.5 3937 54.5 3995 54.5 3995 35.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3966 42.5 0 42 9 -final_tsv ", fillcolor="#94DDF4", height=0.27778, label=final_tsv, pos="3966,45", rects="3937,35.5,3995,54.5", width=0.80556]; intervals_target [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 8789 35.5 8789 54.5 8883 54.5 8883 35.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 8836 42.5 0 78 16 -intervals_target ", fillcolor="#94DDF4", height=0.27778, label=intervals_target, pos="8836,45", rects="8789,35.5,8883,54.5", width=1.3056]; small_candidates [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 9926 35.5 9926 54.5 10028 54.5 10028 35.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 9977 42.5 0 86 16 -small_candidates ", fillcolor="#94DDF4", height=0.27778, label=small_candidates, pos="9977,45", rects="9926,35.5,10028,54.5", width=1.4167]; strelka_filtered_vcf [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 3999 35.5 3999 54.5 4109 54.5 4109 35.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 4054 42.5 0 94 20 -strelka_filtered_vcf ", fillcolor="#94DDF4", height=0.27778, label=strelka_filtered_vcf, pos="4054,45", rects="3999,35.5,4109,54.5", width=1.5278]; cn_diagram [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 8887 35.5 8887 54.5 8961 54.5 8961 35.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 8924 42.5 0 58 10 -cn_diagram ", fillcolor="#94DDF4", height=0.27778, label=cn_diagram, pos="8924,45", rects="8887,35.5,8961,54.5", width=1.0278]; 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docm_filtered_vcf [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 2131 35.5 2131 54.5 2235 54.5 2235 35.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2183 42.5 0 88 17 -docm_filtered_vcf ", fillcolor="#94DDF4", height=0.27778, label=docm_filtered_vcf, pos="2183,45", rects="2131,35.5,2235,54.5", width=1.4444]; somatic_variants [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 10032.5 35.5 10032.5 54.5 10133.5 54.5 10133.5 35.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 10083 42.5 0 85 16 -somatic_variants ", fillcolor="#94DDF4", height=0.27778, label=somatic_variants, pos="10083,45", rects="10032,35.5,10134,54.5", width=1.4028]; vep_summary [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 2239 35.5 2239 54.5 2325 54.5 2325 35.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2282 42.5 0 70 11 -vep_summary ", fillcolor="#94DDF4", height=0.27778, label=vep_summary, pos="2282,45", rects="2239,35.5,2325,54.5", width=1.1944]; tumor_per_target_hs_metrics [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 5247 35.5 5247 54.5 5407 54.5 5407 35.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 5327 42.5 0 144 27 -tumor_per_target_hs_metrics ", fillcolor="#94DDF4", height=0.27778, label=tumor_per_target_hs_metrics, pos="5327,45", rects="5247,35.5,5407,54.5", width=2.2222]; 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vep_cache_dir [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 1470 186.5 1470 205.5 1556 205.5 1556 186.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1513 193.5 0 70 13 -vep_cache_dir ", fillcolor="#94DDF4", height=0.27778, label=vep_cache_dir, pos="1513,196", rects="1470,186.5,1556,205.5", width=1.1944]; synonyms_file [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 2051.5 186.5 2051.5 205.5 2138.5 205.5 2138.5 186.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2095 193.5 0 71 13 -synonyms_file ", fillcolor="#94DDF4", height=0.27778, label=synonyms_file, pos="2095,196", rects="2051.5,186.5,2138.5,205.5", width=1.2083]; somalier_vcf [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 10425 186.5 10425 205.5 10505 205.5 10505 186.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 10465 193.5 0 64 12 -somalier_vcf ", fillcolor="#94DDF4", height=0.27778, label=somalier_vcf, pos="10465,196", rects="10425,186.5,10505,205.5", width=1.1111]; qc_minimum_base_quality [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 7849 186.5 7849 205.5 7997 205.5 7997 186.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 7923 193.5 0 132 23 -qc_minimum_base_quality ", fillcolor="#94DDF4", height=0.27778, label=qc_minimum_base_quality, pos="7923,196", rects="7849,186.5,7997,205.5", width=2.0556]; 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qc_minimum_mapping_quality [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 8001.5 186.5 8001.5 205.5 8168.5 205.5 8168.5 186.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 8085 193.5 0 151 26 -qc_minimum_mapping_quality ", fillcolor="#94DDF4", height=0.27778, label=qc_minimum_mapping_quality, pos="8085,196", rects="8001.5,186.5,8168.5,205.5", width=2.3194]; vep_ensembl_species [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 16 186.5 16 205.5 140 205.5 140 186.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 78 193.5 0 108 19 -vep_ensembl_species ", fillcolor="#94DDF4", height=0.27778, label=vep_ensembl_species, pos="78,196", rects="16,186.5,140,205.5", width=1.7222]; tumor_sequence [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 5443 186.5 5443 205.5 5811 205.5 5811 186.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 5627 193.5 0 352 70 -tumor_sequence: yml file specifying the location of MT sequencing data ", fillcolor="#94DDF4", height=0.27778, label="tumor_sequence: yml file specifying the location of MT sequencing data", pos="5627,196", rects="5443,186.5,5811,205.5", width=5.1111]; cle_vcf_filter [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 144.5 186.5 144.5 205.5 223.5 205.5 223.5 186.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 184 193.5 0 63 14 -cle_vcf_filter ", fillcolor="#94DDF4", height=0.27778, label=cle_vcf_filter, pos="184,196", rects="144.5,186.5,223.5,205.5", width=1.0972]; vep_ensembl_assembly [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 457 186.5 457 205.5 591 205.5 591 186.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 524 193.5 0 118 20 -vep_ensembl_assembly ", fillcolor="#94DDF4", height=0.27778, label=vep_ensembl_assembly, pos="524,196", rects="457,186.5,591,205.5", width=1.8611]; filter_docm_variants [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 819 186.5 819 205.5 935 205.5 935 186.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 877 193.5 0 100 20 -filter_docm_variants ", fillcolor="#94DDF4", height=0.27778, label=filter_docm_variants, pos="877,196", rects="819,186.5,935,205.5", width=1.6111]; known_indels [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 8173 186.5 8173 205.5 8535 205.5 8535 186.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 8354 193.5 0 346 66 -known_indels: File specifying common polymorphic indels from 1000G ", fillcolor="#94DDF4", height=0.27778, label="known_indels: File specifying common polymorphic indels from 1000G", pos="8354,196", rects="8173,186.5,8535,205.5", width=5.0278]; vep_ensembl_version [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 2935.5 186.5 2935.5 205.5 3058.5 205.5 3058.5 186.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2997 193.5 0 107 19 -vep_ensembl_version ", fillcolor="#94DDF4", height=0.27778, label=vep_ensembl_version, pos="2997,196", rects="2935.5,186.5,3058.5,205.5", width=1.7083]; mutect_scatter_count [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 3063 186.5 3063 205.5 3185 205.5 3185 186.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3124 193.5 0 106 20 -mutect_scatter_count ", fillcolor="#94DDF4", height=0.27778, label=mutect_scatter_count, pos="3124,196", rects="3063,186.5,3185,205.5", width=1.6944]; vep_custom_annotations [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 3189.5 186.5 3189.5 205.5 3328.5 205.5 3328.5 186.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3259 193.5 0 123 22 -vep_custom_annotations ", fillcolor="#94DDF4", height=0.27778, label=vep_custom_annotations, pos="3259,196", rects="3189.5,186.5,3328.5,205.5", width=1.9306]; per_target_intervals [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 6942.5 186.5 6942.5 205.5 7475.5 205.5 7475.5 186.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 7209 193.5 0 517 105 -per_target_intervals: additional intervals over which to summarize coverage/\ QC at a per-target resolution ", fillcolor="#94DDF4", height=0.27778, label="per_target_intervals: additional intervals over which to summarize coverage/QC at a per-target resolution", pos="7209,196", rects="6942.5,186.5,7475.5,205.5", width=7.4028]; normal_name [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 9301 186.5 9301 205.5 9611 205.5 9611 186.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 9456 193.5 0 294 56 -normal_name: String specifying the name of the WT sample ", fillcolor="#94DDF4", height=0.27778, label="normal_name: String specifying the name of the WT sample", pos="9456,196", rects="9301,186.5,9611,205.5", width=4.3056]; per_base_intervals [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 4775.5 186.5 4775.5 205.5 5296.5 205.5 5296.5 186.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 5036 193.5 0 505 101 -per_base_intervals: additional intervals over which to summarize coverage/\ QC at a per-base resolution ", fillcolor="#94DDF4", height=0.27778, label="per_base_intervals: additional intervals over which to summarize coverage/QC at a per-base resolution", pos="5036,196", rects="4775.5,186.5,5296.5,205.5", width=7.2361]; trimming [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 5301 186.5 5301 205.5 5363 205.5 5363 186.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 5332 193.5 0 46 8 -trimming ", fillcolor="#94DDF4", height=0.27778, label=trimming, pos="5332,196", rects="5301,186.5,5363,205.5", width=0.86111]; normal_sequence [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 8539 186.5 8539 205.5 8913 205.5 8913 186.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 8726 193.5 0 358 71 -normal_sequence: yml file specifying the location of WT sequencing data ", fillcolor="#94DDF4", height=0.27778, label="normal_sequence: yml file specifying the location of WT sequencing data", pos="8726,196", rects="8539,186.5,8913,205.5", width=5.1944]; normal_sample_name [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 3332.5 186.5 3332.5 205.5 3457.5 205.5 3457.5 186.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3395 193.5 0 109 18 -normal_sample_name ", fillcolor="#94DDF4", height=0.27778, label=normal_sample_name, pos="3395,196", rects="3332.5,186.5,3457.5,205.5", width=1.7361]; summary_intervals [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 7479.5 186.5 7479.5 205.5 7590.5 205.5 7590.5 186.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 7535 193.5 0 95 17 -summary_intervals ", fillcolor="#94DDF4", height=0.27778, label=summary_intervals, pos="7535,196", rects="7479.5,186.5,7590.5,205.5", width=1.5417]; variants_to_table_genotype_fields [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 3462 186.5 3462 205.5 3646 205.5 3646 186.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3554 193.5 0 168 33 -variants_to_table_genotype_fields ", fillcolor="#94DDF4", height=0.27778, label=variants_to_table_genotype_fields, pos="3554,196", rects="3462,186.5,3646,205.5", width=2.5556]; known_variants [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 3650 186.5 3650 205.5 3744 205.5 3744 186.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3697 193.5 0 78 14 -known_variants ", fillcolor="#94DDF4", height=0.27778, label=known_variants, pos="3697,196", rects="3650,186.5,3744,205.5", width=1.3056]; panel_of_normals_vcf [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 939 186.5 939 205.5 1063 205.5 1063 186.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1001 193.5 0 108 20 -panel_of_normals_vcf ", fillcolor="#94DDF4", height=0.27778, label=panel_of_normals_vcf, pos="1001,196", rects="939,186.5,1063,205.5", width=1.7222]; varscan_min_coverage [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 3748.5 186.5 3748.5 205.5 3877.5 205.5 3877.5 186.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3813 193.5 0 113 20 -varscan_min_coverage ", fillcolor="#94DDF4", height=0.27778, label=varscan_min_coverage, pos="3813,196", rects="3748.5,186.5,3877.5,205.5", width=1.7917]; mutect_max_alt_alleles_in_normal_count [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 595 186.5 595 205.5 815 205.5 815 186.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 705 193.5 0 204 38 -mutect_max_alt_alleles_in_normal_count ", fillcolor="#94DDF4", height=0.27778, label=mutect_max_alt_alleles_in_normal_count, pos="705,196", rects="595,186.5,815,205.5", width=3.0556]; vep_pick [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 3882 186.5 3882 205.5 3942 205.5 3942 186.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 3912 193.5 0 44 8 -vep_pick ", fillcolor="#94DDF4", height=0.27778, label=vep_pick, pos="3912,196", rects="3882,186.5,3942,205.5", width=0.83333]; mutect_max_alt_allele_in_normal_fraction [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 227.5 186.5 227.5 205.5 452.5 205.5 452.5 186.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 340 193.5 0 209 40 -mutect_max_alt_allele_in_normal_fraction ", fillcolor="#94DDF4", height=0.27778, label=mutect_max_alt_allele_in_normal_fraction, pos="340,196", rects="227.5,186.5,452.5,205.5", width=3.125]; mills [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 5815.5 186.5 5815.5 205.5 6154.5 205.5 6154.5 186.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 5985 193.5 0 323 66 -mills: File specifying common polymorphic indels from mills et al. ", fillcolor="#94DDF4", height=0.27778, label="mills: File specifying common polymorphic indels from mills et al.", pos="5985,196", rects="5815.5,186.5,6154.5,205.5", width=4.7083]; vep_to_table_fields [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 3946.5 186.5 3946.5 205.5 4057.5 205.5 4057.5 186.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 4002 193.5 0 95 19 -vep_to_table_fields ", fillcolor="#94DDF4", height=0.27778, label=vep_to_table_fields, pos="4002,196", rects="3946.5,186.5,4057.5,205.5", width=1.5417]; } tumor_alignment_and_qc [_draw_="c 7 -#000000 C 7 -#f3cea1 P 4 5730 133.5 5730 152.5 5870 152.5 5870 133.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 5800 140.5 0 124 23 -exome alignment with qc ", fillcolor="#F3CEA1", height=0.27778, label="exome alignment with qc", pos="5800,143", rects="5730,133.5,5870,152.5", width=1.9444]; dbsnp_vcf -> tumor_alignment_and_qc [_draw_="c 7 -#000000 B 10 6255.73 186.5 6224.59 183.31 6188.09 179.97 6155 178 6145.26 177.42 5811.33 176.43 5804 170 5801.26 167.59 5799.84 \ 164.16 5799.18 160.57 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 5801.64 160.71 5798.85 153.84 5796.75 160.95 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 5825 163.6 0 42 9 -dbsnp_vcf ", label=dbsnp_vcf, lp="5825,165.5", pos="e,5798.8,152.33 6255.7,186.5 6224.6,183.31 6188.1,179.97 6155,178 6145.3,177.42 5811.3,176.43 5804,170 5801.3,167.59 5799.8,164.16 \ 5799.2,160.57"]; normal_alignment_and_qc [_draw_="c 7 -#000000 C 7 -#f3cea1 P 4 7541 133.5 7541 152.5 7681 152.5 7681 133.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 7611 140.5 0 124 23 -exome alignment with qc ", fillcolor="#F3CEA1", height=0.27778, label="exome alignment with qc", pos="7611,143", rects="7541,133.5,7681,152.5", width=1.9444]; dbsnp_vcf -> normal_alignment_and_qc [_draw_="c 7 -#000000 B 13 6404.11 186.52 6435.7 183.22 6473.13 179.81 6507 178 6528.44 176.86 7259.81 177.32 7280 170 7285.94 167.85 7285.11 \ 163.28 7291 161 7312.93 152.51 7445.43 147.82 7532.91 145.61 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 7532.78 148.07 7539.72 145.44 7532.66 143.17 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 7312 163.6 0 42 9 -dbsnp_vcf ", label=dbsnp_vcf, lp="7312,165.5", pos="e,7541.2,145.41 6404.1,186.52 6435.7,183.22 6473.1,179.81 6507,178 6528.4,176.86 7259.8,177.32 7280,170 7285.9,167.85 7285.1,163.28 \ 7291,161 7312.9,152.51 7445.4,147.82 7532.9,145.61"]; detect_variants [_draw_="c 7 -#000000 C 7 -#f3cea1 P 4 2828.5 88.5 2828.5 107.5 2967.5 107.5 2967.5 88.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2898 95.5 0 123 24 -Detect Variants workflow ", fillcolor="#F3CEA1", height=0.27778, label="Detect Variants workflow", pos="2898,98", rects="2828.5,88.5,2967.5,107.5", width=1.9306]; reference -> detect_variants [_draw_="c 7 -#000000 B 19 9696.69 186.52 9670.81 183.16 9639.95 179.69 9612 178 9571.23 175.53 6710.18 181.56 6671 170 6663.91 167.91 6664.1 \ 163.09 6657 161 6641.38 156.4 1978.51 164.52 1967 153 1937.16 123.11 1998.6 116.82 2002 116 2080.25 97.22 2617.19 97.69 2820.35 \ 98.56 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2820.08 101.01 2827.09 98.59 2820.1 96.11 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1987 141.1 0 40 9 -reference ", label=reference, lp="1987,143", pos="e,2828.6,98.6 9696.7,186.52 9670.8,183.16 9640,179.69 9612,178 9571.2,175.53 6710.2,181.56 6671,170 6663.9,167.91 6664.1,163.09 \ 6657,161 6641.4,156.4 1978.5,164.52 1967,153 1937.2,123.11 1998.6,116.82 2002,116 2080.2,97.219 2617.2,97.691 2820.3,98.563"]; cnvkit [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 8900.5 88.5 8900.5 107.5 8947.5 107.5 8947.5 88.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 8924 95.5 0 31 6 -cnvkit ", height=0.27778, label=cnvkit, pos="8924,98", rects="8900.5,88.5,8947.5,107.5", width=0.65278]; reference -> cnvkit [_draw_="c 7 -#000000 B 7 9735.31 186.6 9694.06 169.48 9595.2 130.91 9508 116 9400.42 97.61 9061.02 98.12 8955.58 98.76 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 8955.74 96.31 8948.76 98.8 8955.78 101.2 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 9664 141.1 0 40 9 -reference ", label=reference, lp="9664,143", pos="e,8947.2,98.809 9735.3,186.6 9694.1,169.48 9595.2,130.91 9508,116 9400.4,97.608 9061,98.124 8955.6,98.756"]; reference -> tumor_alignment_and_qc [_draw_="c 7 -#000000 B 13 9695.64 186.52 9669.98 183.23 9639.57 179.81 9612 178 9594.79 176.87 9006.69 177.17 8991 170 8986.13 167.78 8987.88 \ 163.21 8983 161 8983 161 6367.27 147.03 5878.24 144.42 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 5878.34 141.97 5871.33 144.38 5878.32 146.87 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 9011 163.6 0 40 9 -reference ", label=reference, lp="9011,165.5", pos="e,5869.8,144.37 9695.6,186.52 9670,183.23 9639.6,179.81 9612,178 9594.8,176.87 9006.7,177.17 8991,170 8986.1,167.78 8987.9,163.21 \ 8983,161 8983,161 6367.3,147.03 5878.2,144.42"]; reference -> normal_alignment_and_qc [_draw_="c 7 -#000000 B 10 9693.88 186.52 9668.59 183.33 9638.93 179.99 9612 178 9354.81 158.98 9289.83 166.32 9032 161 8519.92 150.43 7903.88 \ 145.82 7689.26 144.46 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 7689.4 142.01 7682.38 144.42 7689.37 146.91 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 9497 163.6 0 40 9 -reference ", label=reference, lp="9497,165.5", pos="e,7680.9,144.41 9693.9,186.52 9668.6,183.33 9638.9,179.99 9612,178 9354.8,158.98 9289.8,166.32 9032,161 8519.9,150.43 7903.9,145.82 \ 7689.3,144.46"]; manta [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 9692 88.5 9692 107.5 9836 107.5 9836 88.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 9764 95.5 0 128 24 -Set up and execute manta ", height=0.27778, label="Set up and execute manta", pos="9764,98", rects="9692,88.5,9836,107.5", width=2]; reference -> manta [_draw_="c 7 -#000000 B 4 9755.77 186.82 9757.24 171.09 9760.49 136.4 9762.44 115.63 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 9764.85 116.14 9763.07 108.94 9759.97 115.69 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 9780 141.1 0 40 9 -reference ", label=reference, lp="9780,143", pos="e,9763.2,107.44 9755.8,186.82 9757.2,171.09 9760.5,136.4 9762.4,115.63"]; tumor_bam_to_cram [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 10134 88.5 10134 107.5 10274 107.5 10274 88.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 10204 95.5 0 124 22 -BAM to CRAM conversion ", height=0.27778, label="BAM to CRAM conversion", pos="10204,98", rects="10134,88.5,10274,107.5", width=1.9444]; reference -> tumor_bam_to_cram [_draw_="c 7 -#000000 B 13 9825.66 186.51 9849.01 183.75 9875.11 180.7 9899 178 10002.05 166.36 10034.97 192.15 10131 153 10155.62 142.96 \ 10156.41 131.51 10178 116 10179.89 114.64 10181.88 113.26 10183.88 111.9 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 10184.88 114.18 10189.36 108.26 10182.17 110.09 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 10178 141.1 0 40 9 -reference ", label=reference, lp="10178,143", pos="e,10191,107.43 9825.7,186.51 9849,183.75 9875.1,180.7 9899,178 10002,166.36 10035,192.15 10131,153 10156,142.96 10156,131.51 10178,\ 116 10180,114.64 10182,113.26 10184,111.9"]; concordance [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 9840 88.5 9840 107.5 10130 107.5 10130 88.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 9985 95.5 0 274 49 -Concordance checking between Tumor and Normal BAM ", height=0.27778, label="Concordance checking between Tumor and Normal BAM", pos="9985,98", rects="9840,88.5,10130,107.5", width=4.0278]; reference -> concordance [_draw_="c 7 -#000000 B 7 9853.52 186.5 9885.39 180.47 9919.77 170.26 9948 153 9962.48 144.15 9972.65 127.26 9978.62 114.71 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 9980.73 116 9981.32 108.61 9976.25 114.02 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 9988 141.1 0 40 9 -reference ", label=reference, lp="9988,143", pos="e,9981.9,107.22 9853.5,186.5 9885.4,180.47 9919.8,170.26 9948,153 9962.5,144.15 9972.7,127.26 9978.6,114.71"]; normal_bam_to_cram [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 10278 88.5 10278 107.5 10418 107.5 10418 88.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 10348 95.5 0 124 22 -BAM to CRAM conversion ", height=0.27778, label="BAM to CRAM conversion", pos="10348,98", rects="10278,88.5,10418,107.5", width=1.9444]; reference -> normal_bam_to_cram [_draw_="c 7 -#000000 B 10 9817.63 186.54 9842.86 183.41 9872.27 180.11 9899 178 10032.38 167.46 10069.61 187.04 10199 153 10242.54 141.55 \ 10291.29 122.68 10320.8 110.55 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 10321.67 112.84 10327.2 107.9 10319.79 108.31 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 10281 141.1 0 40 9 -reference ", label=reference, lp="10281,143", pos="e,10329,107.32 9817.6,186.54 9842.9,183.41 9872.3,180.11 9899,178 10032,167.46 10070,187.04 10199,153 10243,141.55 10291,122.68 \ 10321,110.55"]; tumor_name -> tumor_alignment_and_qc [_draw_="c 7 -#000000 B 7 4281.47 186.51 4308.9 183.36 4340.92 180.05 4370 178 4636.19 159.22 5463.29 148.01 5721.9 144.9 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 5721.64 147.35 5728.61 144.81 5721.58 142.45 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 4804 163.6 0 46 10 -final_name ", label=final_name, lp="4804,165.5", pos="e,5730.1,144.8 4281.5,186.51 4308.9,183.36 4340.9,180.05 4370,178 4636.2,159.22 5463.3,148.01 5721.9,144.9"]; manta_call_regions -> manta [_draw_="c 7 -#000000 B 7 9926.73 186.58 9895.84 177.16 9848.53 162.03 9832 153 9811.95 142.04 9791.8 125.13 9778.7 113.15 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 9780.43 111.42 9773.64 108.43 9777.09 115 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 9856.5 141.1 0 49 12 -call_regions ", label=call_regions, lp="9856.5,143", pos="e,9772.5,107.4 9926.7,186.58 9895.8,177.16 9848.5,162.03 9832,153 9811.9,142.04 9791.8,125.13 9778.7,113.15"]; bqsr_intervals -> tumor_alignment_and_qc [_draw_="c 7 -#000000 B 13 6630.91 186.51 6591.81 183.26 6545.72 179.87 6504 178 6467.98 176.38 5889.14 181.61 5855 170 5848.69 167.85 5848.82 \ 164.25 5843 161 5839.59 159.09 5835.92 157.29 5832.21 155.64 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 5833.42 153.49 5826.02 153.02 5831.52 158 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 5884 163.6 0 58 14 -bqsr_intervals ", label=bqsr_intervals, lp="5884,165.5", pos="e,5824.6,152.43 6630.9,186.51 6591.8,183.26 6545.7,179.87 6504,178 6468,176.38 5889.1,181.61 5855,170 5848.7,167.85 5848.8,164.25 \ 5843,161 5839.6,159.09 5835.9,157.29 5832.2,155.64"]; bqsr_intervals -> normal_alignment_and_qc [_draw_="c 7 -#000000 B 13 6817.68 186.5 6856.49 183.33 6901.87 180.01 6943 178 7029.8 173.76 7247.9 181.79 7334 170 7349.91 167.82 7353.15 \ 163.57 7369 161 7423.32 152.18 7485.23 147.94 7532.83 145.89 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 7532.84 148.35 7539.73 145.61 7532.64 143.45 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 7398 163.6 0 58 14 -bqsr_intervals ", label=bqsr_intervals, lp="7398,165.5", pos="e,7541.2,145.55 6817.7,186.5 6856.5,183.33 6901.9,180.01 6943,178 7029.8,173.76 7247.9,181.79 7334,170 7349.9,167.82 7353.1,163.57 \ 7369,161 7423.3,152.18 7485.2,147.94 7532.8,145.89"]; picard_metric_accumulation_level -> tumor_alignment_and_qc [_draw_="c 7 -#000000 B 13 7647.97 186.54 7630.61 183.18 7609.88 179.71 7591 178 7549.72 174.26 6138.28 183.21 6099 170 6092.68 167.87 6093.26 \ 163.29 6087 161 6050.05 147.46 5949.75 144.15 5878.14 143.6 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 5878.53 141.16 5871.51 143.56 5878.49 146.06 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 6168 163.6 0 138 32 -picard_metric_accumulation_level ", label=picard_metric_accumulation_level, lp="6168,165.5", pos="e,5870,143.55 7648,186.54 7630.6,183.18 7609.9,179.71 7591,178 7549.7,174.26 6138.3,183.21 6099,170 6092.7,167.87 6093.3,163.29 \ 6087,161 6050.1,147.46 5949.7,144.15 5878.1,143.6"]; picard_metric_accumulation_level -> normal_alignment_and_qc [_draw_="c 7 -#000000 B 4 7674.45 186.58 7662.46 178.53 7644.21 166.29 7630.36 156.99 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 7632 155.14 7624.83 153.28 7629.27 159.21 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 7718 163.6 0 138 32 -picard_metric_accumulation_level ", label=picard_metric_accumulation_level, lp="7718,165.5", pos="e,7623.6,152.43 7674.5,186.58 7662.5,178.53 7644.2,166.29 7630.4,156.99"]; manta_output_contigs -> manta [_draw_="c 7 -#000000 B 16 10229.64 186.54 10218.07 183.39 10204.49 180.08 10192 178 10146.71 170.47 10134.77 173.69 10089 170 10043.88 166.36 \ 9922.39 179.92 9886 153 9878.3 147.31 9885.07 139.46 9878 133 9866.25 122.27 9851.24 114.91 9836 109.88 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 9836.88 107.59 9829.47 107.89 9835.46 112.28 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 9916.5 141.1 0 61 14 -output_contigs ", label=output_contigs, lp="9916.5,143", pos="e,9828,107.45 10230,186.54 10218,183.39 10204,180.08 10192,178 10147,170.47 10135,173.69 10089,170 10044,166.36 9922.4,179.92 9886,\ 153 9878.3,147.31 9885.1,139.46 9878,133 9866.2,122.27 9851.2,114.91 9836,109.88"]; varscan_strand_filter -> detect_variants [_draw_="c 7 -#000000 B 10 1135.16 186.86 1149.49 173.12 1180.76 145.57 1213 133 1272.22 109.9 1291.57 120.13 1355 116 1644.56 97.13 2548.97 \ 98.02 2820.29 98.74 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2820 101.19 2827.01 98.76 2820.01 96.29 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1255.5 141.1 0 85 21 -varscan_strand_filter ", label=varscan_strand_filter, lp="1255.5,143", pos="e,2828.5,98.766 1135.2,186.86 1149.5,173.12 1180.8,145.57 1213,133 1272.2,109.9 1291.6,120.13 1355,116 1644.6,97.128 2549,98.022 \ 2820.3,98.743"]; varscan_min_var_freq -> detect_variants [_draw_="c 7 -#000000 B 10 1260.48 186.88 1273.65 173.17 1302.49 145.67 1333 133 1387.63 110.31 1405.99 120.14 1465 116 1732.01 97.29 2562.47 \ 98.02 2820.62 98.73 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2820.31 101.18 2827.32 98.75 2820.32 96.28 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1377 141.1 0 88 20 -varscan_min_var_freq ", label=varscan_min_var_freq, lp="1377,143", pos="e,2828.8,98.754 1260.5,186.88 1273.6,173.17 1302.5,145.67 1333,133 1387.6,110.31 1406,120.14 1465,116 1732,97.286 2562.5,98.021 \ 2820.6,98.731"]; target_intervals -> tumor_alignment_and_qc [_draw_="c 7 -#000000 B 7 4663.81 186.51 4698.93 183.5 4739.29 180.3 4776 178 5128.43 155.93 5550.06 147.64 5721.62 145.03 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 5721.62 147.48 5728.58 144.93 5721.55 142.58 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 5145 163.6 0 64 16 -target_intervals ", label=target_intervals, lp="5145,165.5", pos="e,5730.1,144.91 4663.8,186.51 4698.9,183.5 4739.3,180.3 4776,178 5128.4,155.93 5550.1,147.64 5721.6,145.03"]; target_intervals -> normal_alignment_and_qc [_draw_="c 7 -#000000 B 13 4655.19 186.52 4692.2 183.18 4736.22 179.73 4776 178 5193.61 159.82 6239.3 185.91 6657 170 6712.66 167.88 6726.36 \ 163.57 6782 161 7057.91 148.25 7385.93 145.06 7532.94 144.26 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 7532.59 146.72 7539.57 144.23 7532.56 141.82 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 6814 163.6 0 64 16 -target_intervals ", label=target_intervals, lp="6814,165.5", pos="e,7541.1,144.22 4655.2,186.52 4692.2,183.18 4736.2,179.73 4776,178 5193.6,159.82 6239.3,185.91 6657,170 6712.7,167.88 6726.4,163.57 \ 6782,161 7057.9,148.25 7385.9,145.06 7532.9,144.26"]; pad_target_intervals [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 1649 133.5 1649 152.5 1957 152.5 1957 133.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1803 140.5 0 292 59 -expand interval list regions by a given number of basepairs ", height=0.27778, label="expand interval list regions by a given number of basepairs", pos="1803,143", rects="1649,133.5,1957,152.5", width=4.2778]; target_intervals -> pad_target_intervals [_draw_="c 7 -#000000 B 10 4485.73 186.5 4449.21 183.22 4406.05 179.83 4367 178 3298.78 128.01 3029.79 188.97 1961 153 1959.16 152.94 1957.31 \ 152.87 1955.44 152.81 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1955.82 150.37 1948.73 152.55 1955.63 155.26 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 4148.5 163.6 0 47 13 -interval_list ", label=interval_list, lp="4148.5,165.5", pos="e,1947.2,152.49 4485.7,186.5 4449.2,183.22 4406.1,179.83 4367,178 3298.8,128.01 3029.8,188.97 1961,153 1959.2,152.94 1957.3,152.87 \ 1955.4,152.81"]; varscan_max_normal_freq -> detect_variants [_draw_="c 7 -#000000 B 10 1397.49 186.81 1405.55 173 1423.93 145.35 1448 133 1513.6 99.36 1539.4 120.27 1613 116 1849.77 102.26 2579.54 \ 99.62 2820.15 99.12 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2820 101.57 2826.99 99.1 2819.99 96.67 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1501 141.1 0 106 23 -varscan_max_normal_freq ", label=varscan_max_normal_freq, lp="1501,143", pos="e,2828.5,99.099 1397.5,186.81 1405.6,173 1423.9,145.35 1448,133 1513.6,99.356 1539.4,120.27 1613,116 1849.8,102.26 2579.5,99.618 \ 2820.2,99.116"]; omni_vcf -> tumor_alignment_and_qc [_draw_="c 7 -#000000 B 13 7800.23 186.54 7793.99 183.18 7786.37 179.72 7779 178 7737.52 168.35 6286.36 183.57 6246 170 6239.68 167.88 6240.28 \ 163.23 6234 161 6201.52 149.46 5994 145.73 5878.08 144.54 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 5878.43 142.1 5871.41 144.48 5878.38 147 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 6264.5 163.6 0 37 8 -omni_vcf ", label=omni_vcf, lp="6264.5,165.5", pos="e,5869.9,144.46 7800.2,186.54 7794,183.18 7786.4,179.72 7779,178 7737.5,168.35 6286.4,183.57 6246,170 6239.7,167.88 6240.3,163.23 \ 6234,161 6201.5,149.46 5994,145.73 5878.1,144.54"]; omni_vcf -> normal_alignment_and_qc [_draw_="c 7 -#000000 B 7 7810.16 186.68 7805.95 178.61 7798.39 166.77 7788 161 7771.12 151.63 7728.47 147.35 7689.26 145.44 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 7689.58 143 7682.47 145.13 7689.36 147.89 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 7816.5 163.6 0 37 8 -omni_vcf ", label=omni_vcf, lp="7816.5,165.5", pos="e,7681,145.06 7810.2,186.68 7806,178.61 7798.4,166.77 7788,161 7771.1,151.63 7728.5,147.35 7689.3,145.44"]; vep_cache_dir -> detect_variants [_draw_="c 7 -#000000 B 10 1519.93 186.67 1532.17 172.63 1559.19 144.66 1589 133 1703.45 88.23 1742.19 120.79 1865 116 2221.69 102.09 2648.1 \ 99.53 2820.26 99.08 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2820.25 101.53 2827.24 99.07 2820.24 96.63 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1618 141.1 0 58 13 -vep_cache_dir ", label=vep_cache_dir, lp="1618,143", pos="e,2828.8,99.063 1519.9,186.67 1532.2,172.63 1559.2,144.66 1589,133 1703.5,88.225 1742.2,120.79 1865,116 2221.7,102.09 2648.1,99.532 \ 2820.3,99.084"]; synonyms_file -> detect_variants [_draw_="c 7 -#000000 B 19 2114.72 186.54 2123.25 183.27 2133.46 179.86 2143 178 2219.85 162.99 2241.36 180.15 2319 170 2354.18 165.4 2370.43 \ 176.51 2397 153 2404.05 146.76 2396.89 139.18 2404 133 2433.07 107.72 2450.75 120.59 2489 116 2603.78 102.22 2737.82 99.09 2820.31 \ 98.64 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2820.12 101.09 2827.11 98.61 2820.1 96.19 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2433 141.1 0 58 13 -synonyms_file ", label=synonyms_file, lp="2433,143", pos="e,2828.6,98.6 2114.7,186.54 2123.3,183.27 2133.5,179.86 2143,178 2219.9,162.99 2241.4,180.15 2319,170 2354.2,165.4 2370.4,176.51 \ 2397,153 2404.1,146.76 2396.9,139.18 2404,133 2433.1,107.72 2450.7,120.59 2489,116 2603.8,102.22 2737.8,99.09 2820.3,98.637"]; somalier_vcf -> concordance [_draw_="c 7 -#000000 B 10 10448.58 186.55 10422.82 173.57 10371.08 148.58 10325 133 10294.26 122.61 10286.09 120.82 10254 116 10250.57 115.49 \ 10192.75 111.81 10131.58 108.01 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 10131.98 105.58 10124.84 107.59 10131.68 110.47 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 10381.5 141.1 0 13 3 -vcf ", label=vcf, lp="10382,143", pos="e,10123,107.49 10449,186.55 10423,173.57 10371,148.58 10325,133 10294,122.61 10286,120.82 10254,116 10251,115.49 10193,111.81 10132,\ 108.01"]; qc_minimum_base_quality -> tumor_alignment_and_qc [_draw_="c 7 -#000000 B 13 7891.37 186.53 7877.29 183.17 7860.43 179.7 7845 178 7802.12 173.27 6332.89 183.75 6292 170 6285.68 167.88 6286.29 \ 163.22 6280 161 6243.26 148.03 6004.33 144.94 5878.01 144.21 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 5878.39 141.76 5871.37 144.18 5878.36 146.66 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 6345.5 163.6 0 107 23 -qc_minimum_base_quality ", label=qc_minimum_base_quality, lp="6345.5,165.5", pos="e,5869.9,144.17 7891.4,186.53 7877.3,183.17 7860.4,179.7 7845,178 7802.1,173.27 6332.9,183.75 6292,170 6285.7,167.88 6286.3,163.22 \ 6280,161 6243.3,148.03 6004.3,144.94 5878,144.21"]; qc_minimum_base_quality -> normal_alignment_and_qc [_draw_="c 7 -#000000 B 7 7905.82 186.52 7888.61 178.46 7861.14 166.73 7836 161 7788.01 150.07 7732.92 145.77 7689.27 144.23 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 7689.56 141.79 7682.49 144.01 7689.41 146.69 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 7918.5 163.6 0 107 23 -qc_minimum_base_quality ", label=qc_minimum_base_quality, lp="7918.5,165.5", pos="e,7681,143.97 7905.8,186.52 7888.6,178.46 7861.1,166.73 7836,161 7788,150.07 7732.9,145.77 7689.3,144.23"]; strelka_cpu_reserved -> detect_variants [_draw_="c 7 -#000000 B 16 2229.83 186.57 2241.19 183.35 2254.62 179.97 2267 178 2329.42 168.06 2346.82 181.36 2409 170 2433.75 165.48 2444.93 \ 170.51 2463 153 2469.76 146.45 2462.79 139.05 2470 133 2496.17 111.04 2704.4 103.1 2820.48 100.35 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2820.22 102.81 2827.16 100.2 2820.11 97.91 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2513.5 141.1 0 87 20 -strelka_cpu_reserved ", label=strelka_cpu_reserved, lp="2513.5,143", pos="e,2828.7,100.17 2229.8,186.57 2241.2,183.35 2254.6,179.97 2267,178 2329.4,168.06 2346.8,181.36 2409,170 2433.8,165.48 2444.9,170.51 \ 2463,153 2469.8,146.45 2462.8,139.05 2470,133 2496.2,111.04 2704.4,103.1 2820.5,100.35"]; docm_vcf -> detect_variants [_draw_="c 7 -#000000 B 19 2313.58 186.55 2319.95 183.28 2327.63 179.87 2335 178 2395.4 162.63 2413.2 178.05 2475 170 2512.34 165.14 2529.64 \ 177.77 2558 153 2565.09 146.8 2558.19 139.5 2565 133 2584.13 114.75 2595.97 120.62 2622 116 2688.2 104.25 2764.58 100.27 2820.18 \ 99.07 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2820.11 101.52 2827.06 98.94 2820.02 96.62 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2584.5 141.1 0 39 8 -docm_vcf ", label=docm_vcf, lp="2584.5,143", pos="e,2828.6,98.908 2313.6,186.55 2319.9,183.28 2327.6,179.87 2335,178 2395.4,162.63 2413.2,178.05 2475,170 2512.3,165.14 2529.6,177.77 \ 2558,153 2565.1,146.8 2558.2,139.5 2565,133 2584.1,114.75 2596,120.62 2622,116 2688.2,104.25 2764.6,100.27 2820.2,99.071"]; pindel_insert_size -> detect_variants [_draw_="c 7 -#000000 B 19 2410.41 186.57 2420.33 183.34 2432.1 179.97 2443 178 2498.65 167.94 2515.31 184.4 2570 170 2586.72 165.6 2593.5 \ 165.91 2605 153 2611.26 145.97 2604.84 139.11 2612 133 2644.29 105.44 2663.92 121.66 2706 116 2743.46 110.96 2785.24 107.06 2820.23 \ 104.28 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2820.22 106.73 2827 103.75 2819.83 101.85 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2648.5 141.1 0 73 18 -pindel_insert_size ", label=pindel_insert_size, lp="2648.5,143", pos="e,2828.5,103.63 2410.4,186.57 2420.3,183.34 2432.1,179.97 2443,178 2498.7,167.94 2515.3,184.4 2570,170 2586.7,165.6 2593.5,165.91 \ 2605,153 2611.3,145.97 2604.8,139.11 2612,133 2644.3,105.44 2663.9,121.66 2706,116 2743.5,110.96 2785.2,107.06 2820.2,104.28"]; variants_to_table_fields -> detect_variants [_draw_="c 7 -#000000 B 13 2544.64 186.59 2556.2 183.81 2569.14 180.74 2581 178 2627.74 167.21 2650.51 185.27 2686 153 2692.97 146.66 2685.79 \ 139.06 2693 133 2712.16 116.89 2770.79 108.25 2820.46 103.72 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2820.4 106.19 2827.16 103.14 2819.97 101.31 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2741.5 141.1 0 97 24 -variants_to_table_fields ", label=variants_to_table_fields, lp="2741.5,143", pos="e,2828.7,103 2544.6,186.59 2556.2,183.81 2569.1,180.74 2581,178 2627.7,167.21 2650.5,185.27 2686,153 2693,146.66 2685.8,139.06 2693,\ 133 2712.2,116.89 2770.8,108.25 2820.5,103.72"]; annotate_coding_only -> detect_variants [_draw_="c 7 -#000000 B 10 2675.71 186.53 2717.98 175.47 2786.71 157.04 2791 153 2797.86 146.54 2791.31 139.63 2798 133 2808.71 122.38 2822.87 \ 115.08 2837.15 110.05 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2837.72 112.44 2843.63 107.95 2836.22 107.78 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2843.5 141.1 0 91 20 -annotate_coding_only ", label=annotate_coding_only, lp="2843.5,143", pos="e,2845.1,107.49 2675.7,186.53 2718,175.47 2786.7,157.04 2791,153 2797.9,146.54 2791.3,139.63 2798,133 2808.7,122.38 2822.9,115.08 \ 2837.1,110.05"]; manta_non_wgs -> manta [_draw_="c 7 -#000000 B 13 10350.5 186.52 10341.45 183.4 10330.84 180.12 10321 178 10221.35 156.49 10192.77 173.9 10093 153 10039.21 141.73 \ 10029.06 125.92 9975 116 9918.42 105.62 9901.33 112.65 9842.55 108.16 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 9843.06 105.74 9835.88 107.61 9842.66 110.63 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 10111.5 141.1 0 37 7 -non_wgs ", label=non_wgs, lp="10112,143", pos="e,9834.4,107.48 10350,186.52 10341,183.4 10331,180.12 10321,178 10221,156.49 10193,173.9 10093,153 10039,141.73 10029,125.92 9975,\ 116 9918.4,105.62 9901.3,112.65 9842.6,108.16"]; bait_intervals -> cnvkit [_draw_="c 7 -#000000 B 4 9091.08 186.65 9058.77 169.7 8985.36 131.19 8947.52 111.34 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 8948.69 109.19 8941.35 108.1 8946.41 113.53 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 9051.5 141.1 0 55 14 -bait_intervals ", label=bait_intervals, lp="9051.5,143", pos="e,8940,107.4 9091.1,186.65 9058.8,169.7 8985.4,131.19 8947.5,111.34"]; bait_intervals -> tumor_alignment_and_qc [_draw_="c 7 -#000000 B 13 9027.34 186.5 8992.32 183.16 8950.66 179.71 8913 178 8896.96 177.27 6615.64 176.6 6601 170 6596.12 167.8 6597.86 \ 163.24 6593 161 6560.97 146.2 6071.95 144.2 5878.2 143.99 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 5878.27 141.54 5871.27 143.99 5878.27 146.44 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 6628.5 163.6 0 55 14 -bait_intervals ", label=bait_intervals, lp="6628.5,165.5", pos="e,5869.8,143.99 9027.3,186.5 8992.3,183.16 8950.7,179.71 8913,178 8897,177.27 6615.6,176.6 6601,170 6596.1,167.8 6597.9,163.24 6593,\ 161 6561,146.2 6071.9,144.2 5878.2,143.99"]; bait_intervals -> normal_alignment_and_qc [_draw_="c 7 -#000000 B 7 9020.64 186.51 8987.06 183.46 8948.26 180.22 8913 178 8449.69 148.87 7892.13 144.59 7689.46 144.04 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 7689.46 141.59 7682.46 144.03 7689.45 146.49 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 8763.5 163.6 0 55 14 -bait_intervals ", label=bait_intervals, lp="8763.5,165.5", pos="e,7680.9,144.02 9020.6,186.51 8987.1,183.46 8948.3,180.22 8913,178 8449.7,148.87 7892.1,144.59 7689.5,144.04"]; target_interval_padding -> pad_target_intervals [_draw_="c 7 -#000000 B 4 1803.83 186.58 1803.7 179.52 1803.49 169.24 1803.32 160.55 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1805.78 160.73 1803.19 153.78 1800.88 160.82 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1827.5 163.6 0 49 11 -roi_padding ", label=roi_padding, lp="1827.5,165.5", pos="e,1803.2,152.26 1803.8,186.58 1803.7,179.52 1803.5,169.24 1803.3,160.55"]; tumor_sample_name -> detect_variants [_draw_="c 7 -#000000 B 7 2798.45 186.52 2832.29 176.51 2883.95 160.3 2890 153 2894.61 147.43 2896.57 129.32 2897.4 115.59 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2899.83 116 2897.72 108.89 2894.94 115.77 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2937.5 141.1 0 85 17 -tumor_sample_name ", label=tumor_sample_name, lp="2937.5,143", pos="e,2897.8,107.38 2798.5,186.52 2832.3,176.51 2884,160.3 2890,153 2894.6,147.43 2896.6,129.32 2897.4,115.59"]; varscan_p_value -> detect_variants [_draw_="c 7 -#000000 B 7 2906.27 186.51 2934.69 176.32 2978.48 159.77 2983 153 2996.47 132.81 2970.34 118.64 2943.6 109.9 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2944.56 107.63 2937.15 107.91 2943.12 112.31 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3020 141.1 0 68 15 -varscan_p_value ", label=varscan_p_value, lp="3020,143", pos="e,2935.7,107.47 2906.3,186.51 2934.7,176.32 2978.5,159.77 2983,153 2996.5,132.81 2970.3,118.64 2943.6,109.9"]; qc_minimum_mapping_quality -> tumor_alignment_and_qc [_draw_="c 7 -#000000 B 13 8049.67 186.53 8033.95 183.17 8015.15 179.7 7998 178 7954.05 173.63 6449.87 184.07 6408 170 6401.68 167.88 6402.29 \ 163.2 6396 161 6348.46 144.4 6028.9 143.21 5878.27 143.6 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 5878.42 141.15 5871.42 143.62 5878.43 146.05 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 6469.5 163.6 0 123 26 -qc_minimum_mapping_quality ", label=qc_minimum_mapping_quality, lp="6469.5,165.5", pos="e,5869.9,143.62 8049.7,186.53 8033.9,183.17 8015.2,179.7 7998,178 7954,173.63 6449.9,184.07 6408,170 6401.7,167.88 6402.3,163.2 \ 6396,161 6348.5,144.4 6028.9,143.21 5878.3,143.6"]; qc_minimum_mapping_quality -> normal_alignment_and_qc [_draw_="c 7 -#000000 B 7 8063.08 186.57 8040.78 178.43 8005.04 166.53 7973 161 7920.47 151.94 7778.86 147.42 7689.13 145.41 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 7689.44 142.96 7682.39 145.26 7689.33 147.86 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 8071.5 163.6 0 123 26 -qc_minimum_mapping_quality ", label=qc_minimum_mapping_quality, lp="8071.5,165.5", pos="e,7680.9,145.23 8063.1,186.57 8040.8,178.43 8005,166.53 7973,161 7920.5,151.94 7778.9,147.42 7689.1,145.41"]; vep_ensembl_species -> detect_variants [_draw_="c 7 -#000000 B 16 104.68 186.52 116.58 183.16 130.86 179.69 144 178 157.1 176.31 2035.96 178.58 2046 170 2058.66 159.18 2040.19 \ 144.75 2052 133 2056.3 128.72 2153.95 116.54 2160 116 2286.23 104.66 2657.93 100.7 2820.45 99.48 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2820.01 101.93 2826.99 99.43 2819.97 97.03 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2097 141.1 0 90 19 -vep_ensembl_species ", label=vep_ensembl_species, lp="2097,143", pos="e,2828.5,99.419 104.68,186.52 116.58,183.16 130.86,179.69 144,178 157.1,176.31 2036,178.58 2046,170 2058.7,159.18 2040.2,144.75 \ 2052,133 2056.3,128.72 2154,116.54 2160,116 2286.2,104.66 2657.9,100.7 2820.5,99.479"]; tumor_sequence -> tumor_alignment_and_qc [_draw_="c 7 -#000000 B 7 5649.2 186.63 5669.12 179.29 5699.27 168.64 5726 161 5734.26 158.64 5743.11 156.38 5751.72 154.32 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 5752.13 156.74 5758.39 152.76 5751.01 151.97 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 5746.5 163.6 0 41 8 -sequence ", label=sequence, lp="5746.5,165.5", pos="e,5759.9,152.41 5649.2,186.63 5669.1,179.29 5699.3,168.64 5726,161 5734.3,158.64 5743.1,156.38 5751.7,154.32"]; cle_vcf_filter -> detect_variants [_draw_="c 7 -#000000 B 19 201.13 186.53 208.84 183.17 218.17 179.7 227 178 276.91 168.38 2006.42 175.06 2057 170 2095.77 166.12 2113.57 \ 178.53 2143 153 2150.11 146.83 2143.03 139.34 2150 133 2173.37 111.75 2187.7 120.2 2219 116 2332.99 100.71 2667.48 98.85 2820.27 \ 98.83 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2820.23 101.28 2827.23 98.83 2820.23 96.38 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2175.5 141.1 0 51 14 -cle_vcf_filter ", label=cle_vcf_filter, lp="2175.5,143", pos="e,2828.7,98.834 201.13,186.53 208.84,183.17 218.17,179.7 227,178 276.91,168.38 2006.4,175.06 2057,170 2095.8,166.12 2113.6,178.53 \ 2143,153 2150.1,146.83 2143,139.34 2150,133 2173.4,111.75 2187.7,120.2 2219,116 2333,100.71 2667.5,98.853 2820.3,98.833"]; vep_ensembl_assembly -> detect_variants [_draw_="c 7 -#000000 B 19 552.74 186.53 565.55 183.17 580.91 179.7 595 178 681.04 167.62 2069.67 185.18 2155 170 2176.87 166.11 2186.37 \ 168.79 2202 153 2208.62 146.31 2201.74 139 2209 133 2248.83 100.09 2272.53 120.55 2324 116 2501.12 100.34 2710.05 98.25 2820.5 98.42 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2820.41 100.87 2827.42 98.44 2820.42 95.97 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2257.5 141.1 0 97 20 -vep_ensembl_assembly ", label=vep_ensembl_assembly, lp="2257.5,143", pos="e,2828.9,98.439 552.74,186.53 565.55,183.17 580.91,179.7 595,178 681.04,167.62 2069.7,185.18 2155,170 2176.9,166.11 2186.4,168.79 \ 2202,153 2208.6,146.31 2201.7,139 2209,133 2248.8,100.09 2272.5,120.55 2324,116 2501.1,100.34 2710.1,98.249 2820.5,98.421"]; filter_docm_variants -> detect_variants [_draw_="c 7 -#000000 B 19 902.03 186.53 913.2 183.17 926.62 179.71 939 178 1079.34 158.66 2072.95 183.23 2214 170 2255.83 166.08 2275.07 \ 180.31 2307 153 2314.16 146.88 2306.8 139.08 2314 133 2348.44 103.91 2369.15 120.58 2414 116 2556.9 101.41 2724.63 98.72 2820.4 \ 98.55 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2820.36 101 2827.36 98.54 2820.36 96.1 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2355 141.1 0 82 20 -filter_docm_variants ", label=filter_docm_variants, lp="2355,143", pos="e,2828.9,98.539 902.03,186.53 913.2,183.17 926.62,179.71 939,178 1079.3,158.66 2072.9,183.23 2214,170 2255.8,166.08 2275.1,180.31 \ 2307,153 2314.2,146.88 2306.8,139.08 2314,133 2348.4,103.91 2369.2,120.58 2414,116 2556.9,101.41 2724.6,98.722 2820.4,98.548"]; known_indels -> tumor_alignment_and_qc [_draw_="c 7 -#000000 B 13 8278.05 186.52 8244.65 183.18 8204.92 179.74 8169 178 8146.4 176.91 6561.45 177.21 6540 170 6533.68 167.88 6534.3 \ 163.18 6528 161 6497.77 150.53 6060.23 145.99 5878.37 144.55 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 5878.44 142.1 5871.42 144.49 5878.4 147 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 6568 163.6 0 56 12 -known_indels ", label=known_indels, lp="6568,165.5", pos="e,5869.9,144.48 8278,186.52 8244.6,183.18 8204.9,179.74 8169,178 8146.4,176.91 6561.4,177.21 6540,170 6533.7,167.88 6534.3,163.18 \ 6528,161 6497.8,150.53 6060.2,145.99 5878.4,144.55"]; known_indels -> normal_alignment_and_qc [_draw_="c 7 -#000000 B 7 8309.53 186.51 8265.23 178.44 8195.19 166.7 8134 161 7976.73 146.35 7791.85 143.76 7689.4 143.6 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 7689.48 141.15 7682.47 143.6 7689.47 146.05 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 8234 163.6 0 56 12 -known_indels ", label=known_indels, lp="8234,165.5", pos="e,7681,143.59 8309.5,186.51 8265.2,178.44 8195.2,166.7 8134,161 7976.7,146.35 7791.9,143.76 7689.4,143.6"]; vep_ensembl_version -> detect_variants [_draw_="c 7 -#000000 B 7 3015.22 186.54 3037.77 174.92 3071.29 153.19 3055 133 3044.54 120.04 3009.68 111.77 2975.45 106.64 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2976.02 104.24 2968.74 105.68 2975.32 109.1 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3103 141.1 0 88 19 -vep_ensembl_version ", label=vep_ensembl_version, lp="3103,143", pos="e,2967.2,105.46 3015.2,186.54 3037.8,174.92 3071.3,153.19 3055,133 3044.5,120.04 3009.7,111.77 2975.4,106.64"]; mutect_scatter_count -> detect_variants [_draw_="c 7 -#000000 B 7 3131.91 186.87 3143.39 174.09 3161.84 149.1 3148 133 3126.09 107.52 3040.64 100.37 2975.68 98.73 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2976.03 96.29 2968.98 98.58 2975.92 101.18 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3196 141.1 0 88 20 -mutect_scatter_count ", label=mutect_scatter_count, lp="3196,143", pos="e,2967.5,98.548 3131.9,186.87 3143.4,174.09 3161.8,149.1 3148,133 3126.1,107.52 3040.6,100.37 2975.7,98.729"]; vep_custom_annotations -> detect_variants [_draw_="c 7 -#000000 B 7 3259.21 186.72 3259.06 173.26 3256.65 146.77 3241 133 3221.51 115.85 3070.87 106.33 2975.81 101.97 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2975.98 99.53 2968.88 101.66 2975.76 104.43 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3304.5 141.1 0 103 22 -vep_custom_annotations ", label=vep_custom_annotations, lp="3304.5,143", pos="e,2967.4,101.59 3259.2,186.72 3259.1,173.26 3256.7,146.77 3241,133 3221.5,115.85 3070.9,106.33 2975.8,101.97"]; per_target_intervals -> tumor_alignment_and_qc [_draw_="c 7 -#000000 B 13 7096.09 186.5 7047.74 183.22 6990.63 179.83 6939 178 6910.77 177 5948.77 179.04 5922 170 5915.68 167.87 5916.14 \ 163.59 5910 161 5899.9 156.75 5888.87 153.54 5877.82 151.13 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 5878.62 148.8 5871.27 149.82 5877.65 153.6 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 5963 163.6 0 82 20 -per_target_intervals ", label=per_target_intervals, lp="5963,165.5", pos="e,5869.8,149.52 7096.1,186.5 7047.7,183.22 6990.6,179.83 6939,178 6910.8,177 5948.8,179.04 5922,170 5915.7,167.87 5916.1,163.59 \ 5910,161 5899.9,156.75 5888.9,153.54 5877.8,151.13"]; per_target_intervals -> normal_alignment_and_qc [_draw_="c 7 -#000000 B 10 7302 186.51 7341.04 182.39 7386.85 176.85 7428 170 7446.4 166.94 7450.61 164.11 7469 161 7489.64 157.51 7512.09 \ 154.47 7532.91 151.97 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 7532.94 154.43 7539.61 151.18 7532.37 149.57 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 7510 163.6 0 82 20 -per_target_intervals ", label=per_target_intervals, lp="7510,165.5", pos="e,7541.1,151 7302,186.51 7341,182.39 7386.9,176.85 7428,170 7446.4,166.94 7450.6,164.11 7469,161 7489.6,157.51 7512.1,154.47 7532.9,\ 151.97"]; normal_name -> normal_alignment_and_qc [_draw_="c 7 -#000000 B 13 9388.41 186.5 9360.2 183.29 9327.06 179.94 9297 178 9138.62 167.78 9098.57 176.6 8940 170 8874.16 167.26 8857.85 \ 163.47 8792 161 8376.57 145.39 7878.45 143.84 7689.15 143.87 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 7689.43 141.42 7682.43 143.88 7689.43 146.32 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 8963 163.6 0 46 10 -final_name ", label=final_name, lp="8963,165.5", pos="e,7680.9,143.88 9388.4,186.5 9360.2,183.29 9327.1,179.94 9297,178 9138.6,167.78 9098.6,176.6 8940,170 8874.2,167.26 8857.9,163.47 \ 8792,161 8376.6,145.39 7878.4,143.84 7689.1,143.87"]; per_base_intervals -> tumor_alignment_and_qc [_draw_="c 7 -#000000 B 7 5097.38 186.53 5157.15 178.62 5250.63 167.14 5332 161 5468.93 150.66 5628.9 146.57 5721.9 144.98 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 5721.66 147.43 5728.62 144.86 5721.58 142.53 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 5370.5 163.6 0 77 18 -per_base_intervals ", label=per_base_intervals, lp="5370.5,165.5", pos="e,5730.1,144.84 5097.4,186.53 5157.1,178.62 5250.6,167.14 5332,161 5468.9,150.66 5628.9,146.57 5721.9,144.98"]; per_base_intervals -> normal_alignment_and_qc [_draw_="c 7 -#000000 B 13 5145.52 186.52 5193.24 183.2 5249.86 179.77 5301 178 5472.68 172.05 6675.71 183.01 6847 170 6874.33 167.92 6880.7 \ 163.34 6908 161 7027.2 150.8 7375.94 146.26 7532.88 144.68 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 7532.63 147.14 7539.6 144.62 7532.58 142.24 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 6946.5 163.6 0 77 18 -per_base_intervals ", label=per_base_intervals, lp="6946.5,165.5", pos="e,7541.1,144.6 5145.5,186.52 5193.2,183.2 5249.9,179.77 5301,178 5472.7,172.05 6675.7,183.01 6847,170 6874.3,167.92 6880.7,163.34 \ 6908,161 7027.2,150.8 7375.9,146.26 7532.9,144.68"]; trimming -> tumor_alignment_and_qc [_draw_="c 7 -#000000 B 7 5346.17 186.62 5352.36 183.36 5359.83 179.95 5367 178 5431.74 160.41 5615.66 150.85 5721.82 146.65 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 5721.86 149.1 5728.75 146.38 5721.66 144.2 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 5497.5 163.6 0 37 8 -trimming ", label=trimming, lp="5497.5,165.5", pos="e,5730.3,146.32 5346.2,186.62 5352.4,183.36 5359.8,179.95 5367,178 5431.7,160.41 5615.7,150.85 5721.8,146.65"]; trimming -> normal_alignment_and_qc [_draw_="c 7 -#000000 B 10 5345.77 186.54 5352.01 183.18 5359.63 179.71 5367 178 5410.8 167.81 6941.04 171.05 6986 170 6999.48 169.69 7368.36 \ 154.2 7532.97 147.28 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 7532.73 149.75 7539.62 147 7532.53 144.85 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 7213.5 163.6 0 37 8 -trimming ", label=trimming, lp="7213.5,165.5", pos="e,7541.1,146.94 5345.8,186.54 5352,183.18 5359.6,179.71 5367,178 5410.8,167.81 6941,171.05 6986,170 6999.5,169.69 7368.4,154.2 7533,\ 147.28"]; normal_sequence -> normal_alignment_and_qc [_draw_="c 7 -#000000 B 10 8636.16 186.51 8604.24 183.63 8568.03 180.5 8535 178 8414.22 168.85 8384.01 166.36 8263 161 8055.94 151.83 7811.65 \ 147.08 7689.23 145.12 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 7689.53 142.68 7682.5 145.01 7689.46 147.58 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 8446.5 163.6 0 41 8 -sequence ", label=sequence, lp="8446.5,165.5", pos="e,7681,144.99 8636.2,186.51 8604.2,183.63 8568,180.5 8535,178 8414.2,168.85 8384,166.36 8263,161 8055.9,151.83 7811.6,147.08 7689.2,\ 145.12"]; normal_sample_name -> detect_variants [_draw_="c 7 -#000000 B 7 3392.63 186.88 3388.15 173.17 3377.07 145.68 3357 133 3325.63 113.18 3098.17 104.23 2975.67 100.8 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2975.97 98.36 2968.91 100.61 2975.84 103.26 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3421 141.1 0 90 18 -normal_sample_name ", label=normal_sample_name, lp="3421,143", pos="e,2967.4,100.57 3392.6,186.88 3388.2,173.17 3377.1,145.68 3357,133 3325.6,113.18 3098.2,104.23 2975.7,100.8"]; summary_intervals -> tumor_alignment_and_qc [_draw_="c 7 -#000000 B 13 7511.21 186.53 7500.59 183.17 7487.82 179.7 7476 178 7435.78 172.21 6051.52 182.96 6013 170 6006.68 167.87 6007.23 \ 163.37 6001 161 5979.04 152.64 5924.87 148.37 5878.3 146.2 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 5878.61 143.76 5871.51 145.9 5878.4 148.66 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 6051.5 163.6 0 77 17 -summary_intervals ", label=summary_intervals, lp="6051.5,165.5", pos="e,5870,145.83 7511.2,186.53 7500.6,183.17 7487.8,179.7 7476,178 7435.8,172.21 6051.5,182.96 6013,170 6006.7,167.87 6007.2,163.37 \ 6001,161 5979,152.64 5924.9,148.37 5878.3,146.2"]; summary_intervals -> normal_alignment_and_qc [_draw_="c 7 -#000000 B 7 7539.75 186.6 7544.48 178.94 7552.41 167.8 7562 161 7564.69 159.09 7567.62 157.38 7570.65 155.85 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 7571.58 158.12 7576.98 153.03 7569.59 153.64 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 7600.5 163.6 0 77 17 -summary_intervals ", label=summary_intervals, lp="7600.5,165.5", pos="e,7578.4,152.41 7539.8,186.6 7544.5,178.94 7552.4,167.8 7562,161 7564.7,159.09 7567.6,157.38 7570.7,155.85"]; variants_to_table_genotype_fields -> detect_variants [_draw_="c 7 -#000000 B 7 3545.75 186.81 3531.25 172.98 3499.62 145.32 3467 133 3422.3 116.11 3121.14 105.35 2975.96 101.09 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2976.05 98.64 2968.99 100.88 2975.91 103.54 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3573.5 141.1 0 139 33 -variants_to_table_genotype_fields ", label=variants_to_table_genotype_fields, lp="3573.5,143", pos="e,2967.5,100.84 3545.8,186.81 3531.2,172.98 3499.6,145.32 3467,133 3422.3,116.11 3121.1,105.35 2976,101.09"]; known_variants -> detect_variants [_draw_="c 7 -#000000 B 7 3692.81 186.72 3685.23 172.76 3667.81 144.9 3644 133 3585.42 103.72 3154.64 99.48 2975.64 98.99 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2975.83 96.54 2968.83 98.98 2975.82 101.44 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3700 141.1 0 64 14 -known_variants ", label=known_variants, lp="3700,143", pos="e,2967.3,98.972 3692.8,186.72 3685.2,172.76 3667.8,144.9 3644,133 3585.4,103.72 3154.6,99.479 2975.6,98.992"]; varscan_min_coverage -> detect_variants [_draw_="c 7 -#000000 B 10 3805.54 186.84 3792.39 173.06 3763.59 145.47 3733 133 3672.1 108.16 3651.61 120.59 3586 116 3364.99 100.52 3103.19 \ 98.55 2975.64 98.63 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2975.94 96.18 2968.95 98.64 2975.95 101.08 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3814 141.1 0 94 20 -varscan_min_coverage ", label=varscan_min_coverage, lp="3814,143", pos="e,2967.4,98.643 3805.5,186.84 3792.4,173.06 3763.6,145.47 3733,133 3672.1,108.16 3651.6,120.59 3586,116 3365,100.52 3103.2,98.547 \ 2975.6,98.635"]; vep_pick -> detect_variants [_draw_="c 7 -#000000 B 10 3908.16 186.77 3901.17 172.89 3884.98 145.15 3862 133 3779.22 89.22 3745.51 120.84 3652 116 3405.29 103.24 3112.67 \ 100.06 2975.83 99.26 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2975.97 96.81 2968.95 99.22 2975.94 101.71 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3903 141.1 0 36 8 -vep_pick ", label=vep_pick, lp="3903,143", pos="e,2967.4,99.215 3908.2,186.77 3901.2,172.89 3885,145.15 3862,133 3779.2,89.224 3745.5,120.84 3652,116 3405.3,103.24 3112.7,100.06 \ 2975.8,99.262"]; mills -> tumor_alignment_and_qc [_draw_="c 7 -#000000 B 7 5890.91 186.53 5837.35 181.24 5780.07 174.59 5776 170 5772.36 165.89 5774.18 161.49 5778.1 157.49 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 5779.36 159.62 5783.25 153.31 5776.27 155.81 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 5785.5 163.6 0 19 5 -mills ", label=mills, lp="5785.5,165.5", pos="e,5784.4,152.35 5890.9,186.53 5837.3,181.24 5780.1,174.59 5776,170 5772.4,165.89 5774.2,161.49 5778.1,157.49"]; mills -> normal_alignment_and_qc [_draw_="c 7 -#000000 B 13 6056.85 186.51 6088.17 183.19 6125.36 179.76 6159 178 6189.13 176.42 7215.96 178.16 7245 170 7252.48 167.9 7252.56 \ 163.26 7260 161 7309.14 146.1 7445.4 143.45 7532.97 143.37 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 7532.78 145.82 7539.78 143.37 7532.78 140.92 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 7269.5 163.6 0 19 5 -mills ", label=mills, lp="7269.5,165.5", pos="e,7541.3,143.37 6056.8,186.51 6088.2,183.19 6125.4,179.76 6159,178 6189.1,176.42 7216,178.16 7245,170 7252.5,167.9 7252.6,163.26 \ 7260,161 7309.1,146.1 7445.4,143.45 7533,143.37"]; vep_to_table_fields -> detect_variants [_draw_="c 7 -#000000 B 10 3994.56 186.79 3981.45 172.93 3952.69 145.23 3922 133 3851.05 104.73 3827.24 120.54 3751 116 3465.67 99 3125.81 \ 97.97 2975.76 98.49 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2975.96 96.04 2968.97 98.52 2975.98 100.94 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 3995.5 141.1 0 79 19 -vep_to_table_fields ", label=vep_to_table_fields, lp="3995.5,143", pos="e,2967.5,98.524 3994.6,186.79 3981.4,172.93 3952.7,145.23 3922,133 3851.1,104.73 3827.2,120.54 3751,116 3465.7,99 3125.8,97.97 2975.8,\ 98.493"]; detect_variants -> mutect_filtered_vcf [_draw_="c 7 -#000000 B 4 2888.59 88.58 2879.87 80.78 2866.75 69.04 2856.49 59.86 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2858.22 58.12 2851.37 55.27 2854.95 61.77 ", pos="e,2850.2,54.265 2888.6,88.578 2879.9,80.78 2866.7,69.039 2856.5,59.86"]; detect_variants -> pindel_filtered_vcf [_draw_="c 7 -#000000 B 4 2907.25 88.58 2915.81 80.78 2928.7 69.04 2938.78 59.86 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2940.28 61.81 2943.81 55.28 2936.98 58.19 ", pos="e,2944.9,54.265 2907.2,88.578 2915.8,80.78 2928.7,69.039 2938.8,59.86"]; detect_variants -> tumor_indel_bam_readcount_tsv [_draw_="c 7 -#000000 B 4 2931.36 88.58 2966.15 79.79 3020.77 66 3058.37 56.51 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3058.94 58.89 3065.13 54.8 3057.74 54.14 ", pos="e,3066.6,54.434 2931.4,88.578 2966.2,79.793 3020.8,66.003 3058.4,56.51"]; detect_variants -> normal_indel_bam_readcount_tsv [_draw_="c 7 -#000000 B 7 2967.3 90.06 3026.15 83.89 3112.78 74.13 3188 63 3201.99 60.93 3217.09 58.38 3231.04 55.88 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3231.16 58.35 3237.61 54.69 3230.29 53.53 ", pos="e,3239.1,54.426 2967.3,90.064 3026.1,83.889 3112.8,74.129 3188,63 3202,60.93 3217.1,58.376 3231,55.882"]; detect_variants -> pindel_unfiltered_vcf [_draw_="c 7 -#000000 B 7 2967.22 96.23 3060.47 94.24 3231.33 87.27 3375 63 3384.24 61.44 3394.08 59.11 3403.17 56.68 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3403.72 59.07 3409.82 54.84 3402.42 54.35 ", pos="e,3411.3,54.432 2967.2,96.229 3060.5,94.244 3231.3,87.272 3375,63 3384.2,61.44 3394.1,59.114 3403.2,56.679"]; detect_variants -> strelka_unfiltered_vcf [_draw_="c 7 -#000000 B 7 2967.4 95.01 3102.83 90.82 3397.84 80.02 3498 63 3507.52 61.38 3517.67 59.04 3527.06 56.6 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3527.49 59.02 3533.62 54.84 3526.22 54.29 ", pos="e,3535.1,54.448 2967.4,95.015 3102.8,90.82 3397.8,80.017 3498,63 3507.5,61.383 3517.7,59.035 3527.1,56.597"]; detect_variants -> final_vcf [_draw_="c 7 -#000000 B 10 2967.33 95.29 3060.84 92.81 3232.55 87.67 3379 80 3488 74.29 3518.88 92.38 3624 63 3628.16 61.84 3632.4 60.12 \ 3636.4 58.21 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3637.28 60.52 3642.36 55.12 3635.02 56.17 ", pos="e,3643.7,54.419 2967.3,95.288 3060.8,92.811 3232.6,87.666 3379,80 3488,74.294 3518.9,92.375 3624,63 3628.2,61.837 3632.4,60.118 \ 3636.4,58.213"]; detect_variants -> mutect_unfiltered_vcf [_draw_="c 7 -#000000 B 10 2967.09 96.27 3077.32 94.83 3299.76 90.74 3488 80 3576.62 74.94 3599.52 78.06 3687 63 3696.51 61.36 3706.67 59.01 \ 3716.06 56.57 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3716.48 58.99 3722.61 54.81 3715.22 54.26 ", pos="e,3724.1,54.421 2967.1,96.272 3077.3,94.826 3299.8,90.744 3488,80 3576.6,74.942 3599.5,78.063 3687,63 3696.5,61.362 3706.7,59.006 \ 3716.1,56.568"]; detect_variants -> varscan_filtered_vcf [_draw_="c 7 -#000000 B 10 2967.07 96.2 3088.06 94.59 3346.21 90.18 3564 80 3675.25 74.8 3704.23 81.82 3814 63 3822.87 61.48 3832.3 59.19 \ 3841.03 56.79 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3841.63 59.16 3847.69 54.88 3840.28 54.45 ", pos="e,3849.1,54.464 2967.1,96.201 3088.1,94.585 3346.2,90.18 3564,80 3675.2,74.8 3704.2,81.824 3814,63 3822.9,61.479 3832.3,59.193 3841,\ 56.787"]; detect_variants -> final_tsv [_draw_="c 7 -#000000 B 10 2967.48 96.41 3101.99 95.06 3407.34 90.95 3664 80 3783.69 74.89 3817.53 94.88 3933 63 3937.16 61.85 3941.41 60.14 \ 3945.41 58.23 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 3946.29 60.54 3951.37 55.14 3944.03 56.19 ", pos="e,3952.7,54.44 2967.5,96.41 3102,95.055 3407.3,90.953 3664,80 3783.7,74.892 3817.5,94.884 3933,63 3937.2,61.85 3941.4,60.137 3945.4,\ 58.234"]; detect_variants -> strelka_filtered_vcf [_draw_="c 7 -#000000 B 10 2967.42 97.13 3117.09 97.1 3481.27 95.3 3786 80 3879.08 75.33 3903.32 79.76 3995 63 4003.41 61.46 4012.35 59.22 \ 4020.66 56.86 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 4021.23 59.24 4027.26 54.92 4019.85 54.54 ", pos="e,4028.7,54.488 2967.4,97.134 3117.1,97.102 3481.3,95.295 3786,80 3879.1,75.328 3903.3,79.763 3995,63 4003.4,61.461 4012.4,59.217 \ 4020.7,56.86"]; detect_variants -> varscan_unfiltered_vcf [_draw_="c 7 -#000000 B 10 2967.43 97.04 3126.71 96.84 3530.62 94.8 3868 80 3975.72 75.28 4003.54 80.1 4110 63 4120 61.39 4130.68 59 4140.52 \ 56.51 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 4140.93 58.94 4147.08 54.8 4139.69 54.2 ", pos="e,4148.5,54.414 2967.4,97.036 3126.7,96.843 3530.6,94.796 3868,80 3975.7,75.276 4003.5,80.104 4110,63 4120,61.394 4130.7,59 4140.5,\ 56.511"]; detect_variants -> docm_filtered_vcf [_draw_="c 7 -#000000 B 10 2828.62 96.52 2729.93 95.43 2543.4 91.83 2385 80 2319.85 75.14 2302.96 76.32 2239 63 2231.33 61.4 2223.2 59.23 \ 2215.58 56.96 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2216.42 54.66 2209.01 54.94 2214.98 59.34 ", pos="e,2207.6,54.496 2828.6,96.521 2729.9,95.425 2543.4,91.826 2385,80 2319.9,75.136 2303,76.319 2239,63 2231.3,61.403 2223.2,59.225 \ 2215.6,56.962"]; detect_variants -> vep_summary [_draw_="c 7 -#000000 B 7 2828.56 95.43 2698.39 92.06 2422.43 82.78 2329 63 2322.43 61.61 2315.55 59.51 2309.13 57.25 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2310.15 55.02 2302.73 54.88 2308.44 59.61 ", pos="e,2301.3,54.352 2828.6,95.429 2698.4,92.058 2422.4,82.776 2329,63 2322.4,61.61 2315.5,59.508 2309.1,57.252"]; detect_variants -> normal_snv_bam_readcount_tsv [_draw_="c 7 -#000000 B 7 2828.83 93.54 2750.81 89.04 2620.29 79.7 2509 63 2495.56 60.98 2481.09 58.47 2467.68 56 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2468.32 53.63 2460.98 54.75 2467.42 58.44 ", pos="e,2459.5,54.473 2828.8,93.539 2750.8,89.037 2620.3,79.698 2509,63 2495.6,60.984 2481.1,58.471 2467.7,56"]; detect_variants -> final_filtered_vcf [_draw_="c 7 -#000000 B 7 2828.67 92.54 2770.15 87.89 2684.42 78.97 2611 63 2603.65 61.4 2595.87 59.2 2588.6 56.92 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2589.81 54.74 2582.39 54.9 2588.29 59.39 ", pos="e,2581,54.428 2828.7,92.543 2770.2,87.889 2684.4,78.968 2611,63 2603.6,61.401 2595.9,59.203 2588.6,56.918"]; detect_variants -> tumor_snv_bam_readcount_tsv [_draw_="c 7 -#000000 B 4 2864.64 88.58 2829.85 79.79 2775.23 66 2737.63 56.51 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2738.26 54.14 2730.87 54.8 2737.06 58.89 ", pos="e,2729.4,54.434 2864.6,88.578 2829.8,79.793 2775.2,66.003 2737.6,56.51"]; cnvkit -> cn_scatter_plot [_draw_="c 7 -#000000 B 7 8947.21 97.43 9014.12 98.2 9212.84 97.21 9373 63 9379.84 61.54 9387.03 59.4 9393.74 57.13 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 9394.13 59.59 9399.91 54.94 9392.5 54.97 ", pos="e,9401.3,54.439 8947.2,97.429 9014.1,98.199 9212.8,97.213 9373,63 9379.8,61.54 9387,59.402 9393.7,57.132"]; cnvkit -> tumor_segmented_ratios [_draw_="c 7 -#000000 B 7 8947.26 97.26 9022.9 97.74 9268.51 96.43 9468 63 9478.53 61.24 9489.81 58.85 9500.28 56.43 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 9500.75 58.84 9507 54.85 9499.62 54.07 ", pos="e,9508.5,54.497 8947.3,97.259 9022.9,97.738 9268.5,96.431 9468,63 9478.5,61.235 9489.8,58.855 9500.3,56.435"]; cnvkit -> tumor_bin_level_ratios [_draw_="c 7 -#000000 B 7 8900.62 97.19 8824.61 97.46 8577.75 95.58 8377 63 8366.96 61.37 8356.22 58.99 8346.32 56.53 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 8347.09 54.2 8339.7 54.83 8345.87 58.94 ", pos="e,8338.2,54.453 8900.6,97.189 8824.6,97.457 8577.8,95.578 8377,63 8367,61.371 8356.2,58.993 8346.3,56.529"]; cnvkit -> normal_antitarget_coverage [_draw_="c 7 -#000000 B 7 8900.75 96.06 8840.4 93.38 8673.93 84.46 8537 63 8524.98 61.12 8512.06 58.65 8500.1 56.18 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 8500.84 53.83 8493.49 54.79 8499.83 58.62 ", pos="e,8492,54.474 8900.7,96.058 8840.4,93.376 8673.9,84.461 8537,63 8525,61.116 8512.1,58.647 8500.1,56.177"]; cnvkit -> reference_coverage [_draw_="c 7 -#000000 B 7 8900.7 95.22 8853.7 91.39 8744.32 81.17 8654 63 8645.59 61.31 8636.65 59.07 8628.27 56.77 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 8628.98 54.43 8621.58 54.89 8627.65 59.15 ", pos="e,8620.1,54.478 8900.7,95.224 8853.7,91.387 8744.3,81.17 8654,63 8645.6,61.309 8636.6,59.07 8628.3,56.774"]; cnvkit -> tumor_target_coverage [_draw_="c 7 -#000000 B 4 8900.88 91.25 8867.01 82.82 8803.35 66.99 8761.06 56.46 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 8761.75 54.11 8754.37 54.8 8760.57 58.87 ", pos="e,8752.9,54.433 8900.9,91.249 8867,82.823 8803.4,66.986 8761.1,56.463"]; cnvkit -> intervals_target [_draw_="c 7 -#000000 B 4 8909.47 88.58 8895.33 80.38 8873.68 67.83 8857.53 58.48 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 8859.15 56.58 8851.86 55.19 8856.69 60.82 ", pos="e,8850.6,54.434 8909.5,88.578 8895.3,80.384 8873.7,67.835 8857.5,58.48"]; cnvkit -> cn_diagram [_draw_="c 7 -#000000 B 4 8924 88.58 8924 81.52 8924 71.24 8924 62.55 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 8926.45 62.78 8924 55.78 8921.55 62.78 ", pos="e,8924,54.265 8924,88.578 8924,81.523 8924,71.24 8924,62.547"]; cnvkit -> tumor_antitarget_coverage [_draw_="c 7 -#000000 B 4 8943.16 88.58 8962.21 80.2 8991.63 67.27 9013.04 57.85 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 9014.01 60.1 9019.43 55.04 9012.04 55.62 ", pos="e,9020.8,54.434 8943.2,88.578 8962.2,80.199 8991.6,67.267 9013,57.853"]; cnvkit -> normal_target_coverage [_draw_="c 7 -#000000 B 7 8947.31 93.28 8983.37 87.43 9054.81 75.45 9115 63 9124.73 60.99 9135.15 58.64 9144.96 56.34 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 9145.3 58.78 9151.55 54.78 9144.18 54.01 ", pos="e,9153,54.432 8947.3,93.281 8983.4,87.43 9054.8,75.454 9115,63 9124.7,60.987 9135.1,58.639 9145,56.342"]; cnvkit -> intervals_antitarget [_draw_="c 7 -#000000 B 7 8947.14 96.02 9001.49 93.41 9141.33 84.94 9256 63 9264.45 61.38 9273.44 59.13 9281.82 56.79 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 9282.45 59.16 9288.5 54.87 9281.09 54.45 ", pos="e,9290,54.448 8947.1,96.017 9001.5,93.407 9141.3,84.943 9256,63 9264.5,61.382 9273.4,59.13 9281.8,56.793"]; tumor_alignment_and_qc -> tumor_per_target_coverage_metrics [_draw_="c 7 -#000000 B 4 5823.66 133.65 5872.69 116.34 5985.39 76.57 6040.5 57.12 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 6040.99 59.54 6046.77 54.9 6039.36 54.92 ", pos="e,6048.2,54.4 5823.7,133.65 5872.7,116.34 5985.4,76.568 6040.5,57.118"]; tumor_alignment_and_qc -> tumor_hs_metrics [_draw_="c 7 -#000000 B 13 5730.18 141.33 5590.01 139.81 5264.39 135.39 4991 125 4853.56 119.78 4818.91 121.11 4682 108 4535.09 93.93 4497.18 \ 94.53 4353 63 4345.42 61.34 4337.38 59.16 4329.82 56.91 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 4330.72 54.63 4323.31 54.92 4329.29 59.31 ", pos="e,4321.9,54.475 5730.2,141.33 5590,139.81 5264.4,135.39 4991,125 4853.6,119.78 4818.9,121.11 4682,108 4535.1,93.935 4497.2,94.535 \ 4353,63 4345.4,61.342 4337.4,59.16 4329.8,56.915"]; tumor_alignment_and_qc -> tumor_summary_hs_metrics [_draw_="c 7 -#000000 B 10 5730.16 141.97 5576.51 141.35 5197.67 136.74 4882 108 4717.47 93.02 4676.03 89.79 4513 63 4501.11 61.05 4488.33 \ 58.58 4476.47 56.13 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 4477.27 53.79 4469.92 54.75 4476.26 58.59 ", pos="e,4468.4,54.443 5730.2,141.97 5576.5,141.35 5197.7,136.74 4882,108 4717.5,93.022 4676,89.792 4513,63 4501.1,61.046 4488.3,58.576 \ 4476.5,56.128"]; tumor_alignment_and_qc -> tumor_per_base_coverage_metrics [_draw_="c 7 -#000000 B 10 5730.2 140.01 5638.72 137.27 5473.3 131.9 5332 125 5052.31 111.34 4981.89 104.8 4705 63 4690.87 60.87 4675.63 \ 58.34 4661.48 55.89 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 4662.1 53.51 4654.79 54.72 4661.26 58.34 ", pos="e,4653.3,54.46 5730.2,140.01 5638.7,137.27 5473.3,131.9 5332,125 5052.3,111.34 4981.9,104.8 4705,63 4690.9,60.867 4675.6,58.337 \ 4661.5,55.888"]; tumor_alignment_and_qc -> tumor_mark_duplicates_metrics [_draw_="c 7 -#000000 B 10 5730.13 138.83 5663.31 135.7 5559.75 130.59 5470 125 5208.17 108.71 5142.17 103.65 4883 63 4869.85 60.94 4855.69 \ 58.43 4842.54 55.98 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 4843.32 53.64 4835.99 54.75 4842.42 58.45 ", pos="e,4834.5,54.471 5730.1,138.83 5663.3,135.7 5559.8,130.59 5470,125 5208.2,108.71 5142.2,103.65 4883,63 4869.9,60.938 4855.7,58.431 \ 4842.5,55.983"]; tumor_alignment_and_qc -> tumor_alignment_summary_metrics [_draw_="c 7 -#000000 B 13 5730.14 136.46 5689.04 133.18 5636.06 128.92 5589 125 5500.98 117.68 5478.74 118.13 5391 108 5252.7 92.04 5218.54 \ 84.56 5081 63 5066.83 60.78 5051.56 58.27 5037.29 55.87 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 5037.83 53.48 5030.52 54.73 5037.01 58.31 ", pos="e,5029,54.48 5730.1,136.46 5689,133.18 5636.1,128.92 5589,125 5501,117.68 5478.7,118.13 5391,108 5252.7,92.038 5218.5,84.556 5081,\ 63 5066.8,60.779 5051.6,58.27 5037.3,55.875"]; tumor_alignment_and_qc -> tumor_verify_bam_id_metrics [_draw_="c 7 -#000000 B 10 5730.01 133.87 5675.24 127.35 5597.19 117.71 5529 108 5403.35 90.1 5371.92 85.45 5247 63 5235.21 60.88 5222.53 \ 58.43 5210.65 56.07 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 5211.41 53.72 5204.06 54.75 5210.45 58.53 ", pos="e,5202.6,54.452 5730,133.87 5675.2,127.35 5597.2,117.71 5529,108 5403.3,90.098 5371.9,85.45 5247,63 5235.2,60.88 5222.5,58.435 5210.7,\ 56.071"]; tumor_alignment_and_qc -> tumor_per_target_hs_metrics [_draw_="c 7 -#000000 B 7 5756.25 133.52 5721.26 126.72 5670.96 116.86 5627 108 5538.12 90.08 5434.57 68.53 5375.31 56.14 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 5376.08 53.79 5368.73 54.76 5375.08 58.59 ", pos="e,5367.2,54.448 5756.2,133.52 5721.3,126.72 5671,116.86 5627,108 5538.1,90.082 5434.6,68.533 5375.3,56.135"]; tumor_alignment_and_qc -> tumor_verify_bam_id_depth [_draw_="c 7 -#000000 B 4 5772.59 133.56 5715.95 116.14 5586.08 76.18 5523.28 56.86 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 5524.1 54.54 5516.69 54.83 5522.66 59.23 ", pos="e,5515.2,54.382 5772.6,133.56 5715.9,116.14 5586.1,76.177 5523.3,56.856"]; tumor_alignment_and_qc -> tumor_per_base_hs_metrics [_draw_="c 7 -#000000 B 4 5786.6 133.65 5759.64 116.84 5698.67 78.83 5666.6 58.84 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 5668 56.83 5660.76 55.2 5665.4 60.98 ", pos="e,5659.5,54.4 5786.6,133.65 5759.6,116.84 5698.7,78.831 5666.6,58.841"]; tumor_alignment_and_qc -> tumor_insert_size_metrics [_draw_="c 7 -#000000 B 4 5800 133.82 5800 118.17 5800 83.71 5800 62.91 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 5802.45 62.95 5800 55.95 5797.55 62.95 ", pos="e,5800,54.438 5800,133.82 5800,118.17 5800,83.71 5800,62.915"]; tumor_alignment_and_qc -> tumor_flagstats [_draw_="c 7 -#000000 B 4 5810.57 133.82 5831.97 117.25 5880.59 79.61 5906.68 59.41 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 5907.87 61.59 5911.9 55.36 5904.87 57.71 ", pos="e,5913.1,54.438 5810.6,133.82 5832,117.25 5880.6,79.611 5906.7,59.409"]; tumor_alignment_and_qc -> detect_variants [_draw_="c 7 -#000000 B 10 5730.08 141.61 5516.82 140.33 4855.77 135.7 4308 125 4163.53 122.18 4127.47 119.13 3983 116 3605.24 107.81 3153.41 \ 102.02 2975.45 99.89 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2975.73 97.45 2968.7 99.81 2975.67 102.35 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 4331 118.6 0 46 9 -tumor_bam ", label=tumor_bam, lp="4331,120.5", pos="e,2967.2,99.796 5730.1,141.61 5516.8,140.33 4855.8,135.7 4308,125 4163.5,122.18 4127.5,119.13 3983,116 3605.2,107.81 3153.4,102.02 \ 2975.5,99.894"]; tumor_alignment_and_qc -> cnvkit [_draw_="c 7 -#000000 B 4 5869.63 141.04 6300.66 135.11 8596.42 103.51 8892.53 99.43 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 8892.23 101.89 8899.19 99.34 8892.16 96.99 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 7664 118.6 0 46 9 -tumor_bam ", label=tumor_bam, lp="7664,120.5", pos="e,8900.7,99.321 5869.6,141.04 6300.7,135.11 8596.4,103.51 8892.5,99.433"]; tumor_alignment_and_qc -> manta [_draw_="c 7 -#000000 B 7 5869.91 141.67 6233.02 139.94 7906.87 131.72 8426 125 8903.18 118.82 9475.99 105.82 9683.78 100.92 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 9683.76 103.37 9690.7 100.76 9683.64 98.47 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 8963 118.6 0 46 9 -tumor_bam ", label=tumor_bam, lp="8963,120.5", pos="e,9692.2,100.72 5869.9,141.67 6233,139.94 7906.9,131.72 8426,125 8903.2,118.82 9476,105.82 9683.8,100.92"]; tumor_alignment_and_qc -> tumor_bam_to_cram [_draw_="c 7 -#000000 B 10 5869.99 141.59 6105.41 140.22 6890.27 135.74 7539 133 7674.33 132.43 9839.88 132.61 9975 125 10029.91 121.91 10091.87 \ 114.64 10137.48 108.57 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 10137.69 111.02 10144.3 107.66 10137.04 106.16 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 10084.5 118.6 0 19 3 -bam ", label=bam, lp="10084,120.5", pos="e,10146,107.46 5870,141.59 6105.4,140.22 6890.3,135.74 7539,133 7674.3,132.43 9839.9,132.61 9975,125 10030,121.91 10092,114.64 10137,\ 108.57"]; tumor_alignment_and_qc -> concordance [_draw_="c 7 -#000000 B 10 5869.99 141.61 6105.41 140.3 6890.27 136 7539 133 7976.55 130.98 9070.61 137.22 9508 125 9625.01 121.73 9757.98 \ 114.16 9853.75 108.03 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 9853.69 110.49 9860.52 107.6 9853.38 105.6 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 9731 118.6 0 28 5 -bam_1 ", label=bam_1, lp="9731,120.5", pos="e,9862,107.5 5870,141.61 6105.4,140.3 6890.3,136 7539,133 7976.6,130.98 9070.6,137.22 9508,125 9625,121.73 9758,114.16 9853.8,108.03"]; normal_alignment_and_qc -> normal_verify_bam_id_metrics [_draw_="c 7 -#000000 B 10 7541.15 142.27 7387.92 142.23 7010.9 138.71 6697 108 6540.03 92.64 6500.73 87.97 6345 63 6332.27 60.96 6318.56 \ 58.46 6305.84 56.01 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 6306.47 53.64 6299.14 54.7 6305.54 58.45 ", pos="e,6297.6,54.413 7541.1,142.27 7387.9,142.23 7010.9,138.71 6697,108 6540,92.643 6500.7,87.97 6345,63 6332.3,60.959 6318.6,58.458 \ 6305.8,56.01"]; normal_alignment_and_qc -> normal_per_base_coverage_metrics [_draw_="c 7 -#000000 B 7 7541.25 141.48 7408.1 139.91 7108.61 133.58 6858 108 6727.77 94.71 6575.96 69.73 6496.3 55.88 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 6497.16 53.54 6489.84 54.75 6496.32 58.37 ", pos="e,6488.4,54.489 7541.3,141.48 7408.1,139.91 7108.6,133.58 6858,108 6727.8,94.708 6576,69.725 6496.3,55.876"]; normal_alignment_and_qc -> normal_verify_bam_id_depth [_draw_="c 7 -#000000 B 10 7541.06 138.89 7472.7 135.76 7365.66 130.6 7273 125 7019.08 109.66 6954.75 105.83 6704 63 6692.22 60.99 6679.56 \ 58.54 6667.76 56.14 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 6668.58 53.81 6661.23 54.79 6667.59 58.6 ", pos="e,6659.7,54.486 7541.1,138.89 7472.7,135.76 7365.7,130.6 7273,125 7019.1,109.66 6954.8,105.83 6704,63 6692.2,60.988 6679.6,58.54 \ 6667.8,56.137"]; normal_alignment_and_qc -> normal_per_target_hs_metrics [_draw_="c 7 -#000000 B 13 7541.44 136.62 7499.1 133.32 7443.93 128.98 7395 125 7305.2 117.69 7282.53 118.07 7193 108 7050.72 91.99 7015.2 \ 86.74 6874 63 6861.79 60.95 6848.67 58.51 6836.41 56.12 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 6836.9 53.72 6829.56 54.78 6835.96 58.53 ", pos="e,6828.1,54.489 7541.4,136.62 7499.1,133.32 7443.9,128.98 7395,125 7305.2,117.69 7282.5,118.07 7193,108 7050.7,91.99 7015.2,86.738 \ 6874,63 6861.8,60.948 6848.7,58.507 6836.4,56.124"]; normal_alignment_and_qc -> normal_per_base_hs_metrics [_draw_="c 7 -#000000 B 7 7541.39 134.06 7433.15 121.35 7218.09 94.62 7037 63 7025.21 60.94 7012.54 58.5 7000.7 56.12 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 7001.49 53.78 6994.14 54.78 7000.51 58.58 ", pos="e,6992.7,54.481 7541.4,134.06 7433.1,121.35 7218.1,94.617 7037,63 7025.2,60.942 7012.5,58.498 7000.7,56.115"]; normal_alignment_and_qc -> normal_mark_duplicates_metrics [_draw_="c 7 -#000000 B 4 7568.38 133.56 7479.1 115.89 7272.77 75.05 7176.8 56.05 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 7177.52 53.7 7170.18 54.74 7176.57 58.51 ", pos="e,7168.7,54.45 7568.4,133.56 7479.1,115.89 7272.8,75.051 7176.8,56.055"]; normal_alignment_and_qc -> normal_alignment_summary_metrics [_draw_="c 7 -#000000 B 4 7585.43 133.56 7532.71 116.17 7411.97 76.34 7353.27 56.97 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 7354.26 54.72 7346.84 54.86 7352.72 59.38 ", pos="e,7345.4,54.382 7585.4,133.56 7532.7,116.17 7412,76.34 7353.3,56.974"]; normal_alignment_and_qc -> normal_insert_size_metrics [_draw_="c 7 -#000000 B 4 7601.54 133.82 7582.54 117.39 7539.6 80.25 7516.1 59.93 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 7517.8 58.15 7510.9 55.43 7514.59 61.86 ", pos="e,7509.8,54.438 7601.5,133.82 7582.5,117.39 7539.6,80.25 7516.1,59.928"]; normal_alignment_and_qc -> normal_summary_hs_metrics [_draw_="c 7 -#000000 B 4 7615.18 133.82 7623.31 117.88 7641.39 82.46 7651.93 61.8 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 7654 63.13 7655.01 55.79 7649.64 60.91 ", pos="e,7655.7,54.438 7615.2,133.82 7623.3,117.88 7641.4,82.463 7651.9,61.804"]; normal_alignment_and_qc -> normal_hs_metrics [_draw_="c 7 -#000000 B 4 7627.44 133.65 7660.95 116.63 7737.26 77.87 7776.2 58.09 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 7776.98 60.44 7782.11 55.09 7774.76 56.07 ", pos="e,7783.5,54.4 7627.4,133.65 7661,116.63 7737.3,77.866 7776.2,58.09"]; normal_alignment_and_qc -> normal_per_target_coverage_metrics [_draw_="c 7 -#000000 B 4 7641.58 133.56 7705.01 116.07 7850.79 75.85 7920.5 56.62 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 7921.06 59.01 7927.16 54.78 7919.76 54.28 ", pos="e,7928.6,54.382 7641.6,133.56 7705,116.07 7850.8,75.851 7920.5,56.62"]; normal_alignment_and_qc -> normal_flagstats [_draw_="c 7 -#000000 B 7 7675 133.51 7762.46 121.27 7923.87 96.42 8059 63 8065.88 61.3 8073.16 59.18 8080.06 57.02 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 8080.57 59.43 8086.48 54.95 8079.07 54.76 ", pos="e,8087.9,54.485 7675,133.51 7762.5,121.27 7923.9,96.421 8059,63 8065.9,61.299 8073.2,59.178 8080.1,57.017"]; normal_alignment_and_qc -> detect_variants [_draw_="c 7 -#000000 B 4 7541.18 141.36 7004.58 136.47 3541.17 104.87 2975.94 99.71 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2975.97 97.26 2968.95 99.65 2975.93 102.16 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 5701.5 118.6 0 51 10 -normal_bam ", label=normal_bam, lp="5701.5,120.5", pos="e,2967.4,99.634 7541.2,141.36 7004.6,136.47 3541.2,104.87 2975.9,99.711"]; normal_alignment_and_qc -> cnvkit [_draw_="c 7 -#000000 B 4 7680.67 139.72 7922.86 131.79 8722.67 105.59 8892.23 100.04 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 8892.3 102.49 8899.21 99.81 8892.14 97.59 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 8405 118.6 0 40 9 -reference ", label=reference, lp="8405,120.5", pos="e,8900.7,99.762 7680.7,139.72 7922.9,131.79 8722.7,105.59 8892.2,100.04"]; normal_alignment_and_qc -> manta [_draw_="c 7 -#000000 B 7 7680.92 142.25 7906.76 142.85 8637.06 143.15 9241 125 9397.88 120.28 9581.03 110.1 9683.66 103.97 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 9683.78 106.42 9690.62 103.56 9683.48 101.53 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 9481.5 118.6 0 51 10 -normal_bam ", label=normal_bam, lp="9481.5,120.5", pos="e,9692.1,103.47 7680.9,142.25 7906.8,142.85 8637.1,143.15 9241,125 9397.9,120.28 9581,110.1 9683.7,103.97"]; normal_alignment_and_qc -> concordance [_draw_="c 7 -#000000 B 10 7680.87 141.6 8066.19 139.38 9915.02 128.53 9929 125 9937.29 122.91 9938.3 119.71 9946 116 9949.63 114.25 9953.49 \ 112.47 9957.32 110.76 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 9958.22 113.03 9963.64 107.97 9956.25 108.55 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 9960 118.6 0 28 5 -bam_2 ", label=bam_2, lp="9960,120.5", pos="e,9965,107.36 7680.9,141.6 8066.2,139.38 9915,128.53 9929,125 9937.3,122.91 9938.3,119.71 9946,116 9949.6,114.25 9953.5,112.47 9957.3,\ 110.76"]; normal_alignment_and_qc -> normal_bam_to_cram [_draw_="c 7 -#000000 B 7 7680.95 141.56 8087.53 138.99 10129.19 126.06 10145 125 10192.99 121.78 10246.99 114.69 10287.22 108.73 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 10287.54 111.16 10294.1 107.7 10286.81 106.32 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 10243.5 118.6 0 19 3 -bam ", label=bam, lp="10244,120.5", pos="e,10296,107.48 7680.9,141.56 8087.5,138.99 10129,126.06 10145,125 10193,121.78 10247,114.69 10287,108.73"]; normal_index_cram [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 10710.5 35.5 10710.5 54.5 10829.5 54.5 10829.5 35.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 10770 42.5 0 103 19 -samtools index cram ", height=0.27778, label="samtools index cram", pos="10770,45", rects="10710,35.5,10830,54.5", width=1.6528]; normal_index_cram -> normal_cram [_draw_="c 7 -#000000 B 10 10754.93 54.41 10742.17 61.79 10723.13 71.46 10705 75.5 10652.94 87.11 10276.14 90.64 10225 75.5 10214.07 72.26 \ 10203.3 65.6 10194.83 59.32 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 10196.52 57.54 10189.5 55.16 10193.51 61.4 ", pos="e,10188,54.227 10755,54.412 10742,61.789 10723,71.458 10705,75.5 10653,87.106 10276,90.639 10225,75.5 10214,72.264 10203,65.6 10195,\ 59.324"]; manta -> tumor_only_variants [_draw_="c 7 -#000000 B 4 9764 88.58 9764 81.52 9764 71.24 9764 62.55 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 9766.45 62.78 9764 55.78 9761.55 62.78 ", pos="e,9764,54.265 9764,88.578 9764,81.523 9764,71.24 9764,62.547"]; manta -> diploid_variants [_draw_="c 7 -#000000 B 4 9782.16 88.58 9800.16 80.24 9827.88 67.38 9848.17 57.98 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 9849.12 60.24 9854.44 55.07 9847.05 55.79 ", pos="e,9855.8,54.434 9782.2,88.578 9800.2,80.236 9827.9,67.381 9848.2,57.978"]; manta -> small_candidates [_draw_="c 7 -#000000 B 7 9808.51 88.51 9840.31 82.18 9884 72.94 9922 63 9928.95 61.18 9936.33 59.04 9943.36 56.91 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 9943.98 59.28 9949.95 54.87 9942.53 54.6 ", pos="e,9951.4,54.427 9808.5,88.507 9840.3,82.178 9884,72.942 9922,63 9928.9,61.182 9936.3,59.045 9943.4,56.911"]; manta -> somatic_variants [_draw_="c 7 -#000000 B 7 9835.21 88.52 9907.21 79.85 10010.45 67.08 10029 63 10036.4 61.37 10044.24 59.18 10051.59 56.92 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 10051.95 59.37 10057.88 54.91 10050.47 54.71 ", pos="e,10059,54.455 9835.2,88.524 9907.2,79.848 10010,67.075 10029,63 10036,61.373 10044,59.184 10052,56.919"]; manta -> all_candidates [_draw_="c 7 -#000000 B 4 9746.5 88.58 9729.23 80.27 9702.68 67.49 9683.15 58.1 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 9684.26 55.92 9676.89 55.09 9682.14 60.33 ", pos="e,9675.5,54.434 9746.5,88.578 9729.2,80.273 9702.7,67.495 9683.2,58.103"]; tumor_index_cram [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 10587.5 35.5 10587.5 54.5 10706.5 54.5 10706.5 35.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 10647 42.5 0 103 19 -samtools index cram ", height=0.27778, label="samtools index cram", pos="10647,45", rects="10588,35.5,10706,54.5", width=1.6528]; tumor_bam_to_cram -> tumor_index_cram [_draw_="c 7 -#000000 B 10 10272.92 88.53 10274.63 88.35 10276.33 88.17 10278 88 10411.98 74.31 10447.16 85.19 10580 63 10589.89 61.35 10600.47 \ 58.96 10610.23 56.5 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 10610.58 58.94 10616.74 54.8 10609.34 54.2 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 10532.5 73.6 0 21 4 -cram ", label=cram, lp="10532,75.5", pos="e,10618,54.423 10273,88.529 10275,88.348 10276,88.171 10278,88 10412,74.312 10447,85.193 10580,63 10590,61.347 10600,58.961 10610,\ 56.497"]; concordance -> somalier_concordance_statistics [_draw_="c 7 -#000000 B 7 10047.67 88.56 10094.85 82.04 10161.08 72.56 10219 63 10231.88 60.87 10245.75 58.41 10258.71 56.02 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 10259.15 58.43 10265.58 54.75 10258.25 53.62 ", pos="e,10267,54.473 10048,88.56 10095,82.045 10161,72.556 10219,63 10232,60.875 10246,58.408 10259,56.023"]; concordance -> somalier_concordance_metrics [_draw_="c 7 -#000000 B 7 10106.08 88.52 10207.59 81.15 10344.43 70.49 10399 63 10412.4 61.16 10426.86 58.61 10440.1 56.04 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 10440.29 58.5 10446.68 54.74 10439.34 53.69 ", pos="e,10448,54.448 10106,88.524 10208,81.146 10344,70.489 10399,63 10412,61.16 10427,58.609 10440,56.042"]; tumor_index_cram -> tumor_cram [_draw_="c 7 -#000000 B 10 10630.92 54.42 10617.34 61.8 10597.09 71.47 10578 75.5 10514.65 88.88 8308.8 94.82 8247 75.5 8236.6 72.25 8226.51 \ 65.58 8218.61 59.31 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 8220.64 57.81 8213.7 55.19 8217.49 61.57 ", pos="e,8212.5,54.217 10631,54.418 10617,61.797 10597,71.468 10578,75.5 10515,88.878 8308.8,94.825 8247,75.5 8236.6,72.249 8226.5,65.583 \ 8218.6,59.31"]; pad_target_intervals -> detect_variants [_draw_="c 7 -#000000 B 7 1830.66 133.57 1852.3 127.41 1883.26 119.53 1911 116 1999.91 104.67 2602.65 100.51 2820.03 99.36 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2820.04 101.81 2827.02 99.32 2820.01 96.91 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 1936 118.6 0 50 13 -roi_intervals ", label=roi_intervals, lp="1936,120.5", pos="e,2828.5,99.317 1830.7,133.57 1852.3,127.41 1883.3,119.53 1911,116 1999.9,104.67 2602.7,100.51 2820,99.361"]; normal_bam_to_cram -> normal_index_cram [_draw_="c 7 -#000000 B 7 10417.97 93.88 10490.67 89.82 10607.51 81 10707 63 10716.05 61.36 10725.69 59.06 10734.64 56.67 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 10735.07 59.09 10741.17 54.87 10733.77 54.37 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 10658.5 73.6 0 21 4 -cram ", label=cram, lp="10658,75.5", pos="e,10743,54.468 10418,93.88 10491,89.821 10608,81.001 10707,63 10716,61.363 10726,59.056 10735,56.667"]; default1 [_draw_="c 7 -#000000 C 7 -#d5aefc P 4 2009 133.5 2009 152.5 2045 152.5 2045 133.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 2027 140.5 0 20 4 -true ", fillcolor="#D5AEFC", height=0.27778, label=true, pos="2027,143", rects="2009,133.5,2045,152.5", width=0.5]; default1 -> detect_variants [_draw_="c 7 -#000000 B 7 2013.53 133.69 2006.56 128.41 2000.55 121.55 2006 116 2020.17 101.56 2605.5 99.37 2820.15 99.05 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 2820.04 101.5 2827.03 99.04 2820.03 96.6 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 2049 118.6 0 86 18 -strelka_exome_mode ", label=strelka_exome_mode, lp="2049,120.5", pos="e,2828.5,99.037 2013.5,133.69 2006.6,128.41 2000.6,121.55 2006,116 2020.2,101.56 2605.5,99.367 2820.1,99.048"]; }