digraph workflow {
	graph [_draw_="c 9 -#fffffe00 C 7 -#eeeeee P 4 0 0 0 233 898 233 898 0 ",
		bb="0,0,898,233",
		bgcolor="#eeeeee",
		clusterrank=local,
		color=black,
		dpi=96,
		fontsize=10,
		labeljust=left,
		nodesep=0.05,
		ranksep=0.22,
		xdotversion=1.7
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	node [color=black,
		fillcolor=lightgoldenrodyellow,
		fontcolor=black,
		fontname=Helvetica,
		fontsize=10,
		height=0,
		label="\N",
		shape=record,
		style=filled,
		width=0
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	edge [arrowsize=0.7,
		color=black,
		fontcolor=black,
		fontname=Helvetica,
		fontsize=8
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	subgraph cluster_inputs {
		graph [_draw_="S 6 -dashed c 7 -#000000 C 7 -#eeeeee P 4 103 170 103 225 890 225 890 170 ",
			_ldraw_="F 10 11 -Times-Roman c 7 -#000000 T 153 213 0 84 15 -Workflow Inputs ",
			bb="103,170,890,225",
			label="Workflow Inputs",
			lheight=0.15,
			lp="153,215.5",
			lwidth=1.17,
			rank=same,
			style=dashed
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		drop_low_coverage	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 111.5 178.5 111.5 197.5 222.5 197.5 222.5 178.5 ",
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			pos="167,188",
			rects="111.5,178.5,222.5,197.5",
			width=1.5417];
		cnvkit_vcf_name	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 690 178.5 690 197.5 790 197.5 790 178.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 740 185.5 0 84 15 -cnvkit_vcf_name ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=cnvkit_vcf_name,
			pos="740,188",
			rects="690,178.5,790,197.5",
			width=1.3889];
		method	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 227 178.5 227 197.5 281 197.5 281 178.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 254 185.5 0 38 6 -method ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=method,
			pos="254,188",
			rects="227,178.5,281,197.5",
			width=0.75];
		diagram	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 285.5 178.5 285.5 197.5 342.5 197.5 342.5 178.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 314 185.5 0 41 7 -diagram ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=diagram,
			pos="314,188",
			rects="285.5,178.5,342.5,197.5",
			width=0.79167];
		scatter_plot	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 347 178.5 347 197.5 421 197.5 421 178.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 384 185.5 0 58 12 -scatter_plot ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=scatter_plot,
			pos="384,188",
			rects="347,178.5,421,197.5",
			width=1.0278];
		male_reference	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 592.5 178.5 592.5 197.5 685.5 197.5 685.5 178.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 639 185.5 0 77 14 -male_reference ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=male_reference,
			pos="639,188",
			rects="592.5,178.5,685.5,197.5",
			width=1.2917];
		reference_cnn	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 425 178.5 425 197.5 511 197.5 511 178.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 468 185.5 0 70 13 -reference_cnn ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=reference_cnn,
			pos="468,188",
			rects="425,178.5,511,197.5",
			width=1.1944];
		segment_filter	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 794.5 178.5 794.5 197.5 881.5 197.5 881.5 178.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 838 185.5 0 71 14 -segment_filter ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=segment_filter,
			pos="838,188",
			rects="794.5,178.5,881.5,197.5",
			width=1.2083];
		tumor_bam	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 515.5 178.5 515.5 197.5 588.5 197.5 588.5 178.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 552 185.5 0 57 9 -tumor_bam ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=tumor_bam,
			pos="552,188",
			rects="515.5,178.5,588.5,197.5",
			width=1.0139];
	}
	subgraph cluster_outputs {
		graph [_draw_="S 6 -dashed c 7 -#000000 C 7 -#eeeeee P 4 8 8 8 63 829 63 829 8 ",
			_ldraw_="F 10 11 -Times-Roman c 7 -#000000 T 62 15 0 92 16 -Workflow Outputs ",
			bb="8,8,829,63",
			label="Workflow Outputs",
			labelloc=b,
			lheight=0.15,
			lp="62,17.5",
			lwidth=1.28,
			rank=same,
			style=dashed
		];
		cn_diagram	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 408 35.5 408 54.5 482 54.5 482 35.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 445 42.5 0 58 10 -cn_diagram ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=cn_diagram,
			pos="445,45",
			rects="408,35.5,482,54.5",
			width=1.0278];
		cnvkit_vcf	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 753.5 35.5 753.5 54.5 820.5 54.5 820.5 35.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 787 42.5 0 51 10 -cnvkit_vcf ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=cnvkit_vcf,
			pos="787,45",
			rects="753.5,35.5,820.5,54.5",
			width=0.93056];
		tumor_bin_level_ratios	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 486 35.5 486 54.5 614 54.5 614 35.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 550 42.5 0 112 22 -tumor_bin_level_ratios ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=tumor_bin_level_ratios,
			pos="550,45",
			rects="486,35.5,614,54.5",
			width=1.7778];
		tumor_target_coverage	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 618.5 35.5 618.5 54.5 749.5 54.5 749.5 35.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 684 42.5 0 115 21 -tumor_target_coverage ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=tumor_target_coverage,
			pos="684,45",
			rects="618.5,35.5,749.5,54.5",
			width=1.8194];
		cn_scatter_plot	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 16.5 35.5 16.5 54.5 107.5 54.5 107.5 35.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 62 42.5 0 75 15 -cn_scatter_plot ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=cn_scatter_plot,
			pos="62,45",
			rects="16.5,35.5,107.5,54.5",
			width=1.2639];
		tumor_segmented_ratios	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 111.5 35.5 111.5 54.5 250.5 54.5 250.5 35.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 181 42.5 0 123 22 -tumor_segmented_ratios ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=tumor_segmented_ratios,
			pos="181,45",
			rects="111.5,35.5,250.5,54.5",
			width=1.9306];
		tumor_antitarget_coverage	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 254.5 35.5 254.5 54.5 403.5 54.5 403.5 35.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 329 42.5 0 133 25 -tumor_antitarget_coverage ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=tumor_antitarget_coverage,
			pos="329,45",
			rects="254.5,35.5,403.5,54.5",
			width=2.0694];
	}
	cnvkit_main	[_draw_="c 7 -#000000 C 7 -#fafad2 P 4 406.5 125.5 406.5 144.5 483.5 144.5 483.5 125.5 ",
		_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 445 132.5 0 61 11 -cnvkit_main ",
		height=0.27778,
		label=cnvkit_main,
		pos="445,135",
		rects="406.5,125.5,483.5,144.5",
		width=1.0694];
	drop_low_coverage -> cnvkit_main	[_draw_="c 7 -#000000 B 7 174.62 178.57 182.56 170.42 195.81 158.52 210 153 243.16 140.11 339.75 136.89 398.27 136.15 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 398.13 138.6 405.1 136.07 398.07 133.7 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 249.5 155.6 0 79 17 -drop_low_coverage ",
		label=drop_low_coverage,
		lp="249.5,157.5",
		pos="e,406.61,136.06 174.62,178.57 182.56,170.42 195.81,158.52 210,153 243.16,140.11 339.75,136.89 398.27,136.15"];
	cns_to_vcf	[_draw_="c 7 -#000000 C 7 -#fafad2 P 4 527.5 80.5 527.5 99.5 822.5 99.5 822.5 80.5 ",
		_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 675 87.5 0 279 57 -Convert default cnvkit .cns output to standard vcf format ",
		height=0.27778,
		label="Convert default cnvkit .cns output to standard vcf format",
		pos="675,90",
		rects="527.5,80.5,822.5,99.5",
		width=4.0972];
	cnvkit_vcf_name -> cns_to_vcf	[_draw_="c 7 -#000000 B 7 739.66 178.62 738.77 165.93 735.56 141.6 724 125 717.9 116.24 708.76 109.02 700.02 103.52 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 701.44 101.51 694.16 100.08 698.95 105.73 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 760.5 133.1 0 55 11 -output_name ",
		label=output_name,
		lp="760.5,135",
		pos="e,692.85,99.309 739.66,178.62 738.77,165.93 735.56,141.6 724,125 717.9,116.24 708.76,109.02 700.02,103.52"];
	method -> cnvkit_main	[_draw_="c 7 -#000000 B 7 264.47 178.77 275.24 170.77 292.82 158.99 310 153 338.38 143.11 371.9 138.85 398.43 137.07 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 398.43 139.52 405.28 136.66 398.14 134.63 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 326 155.6 0 32 6 -method ",
		label=method,
		lp="326,157.5",
		pos="e,406.79,136.57 264.47,178.77 275.24,170.77 292.82,158.99 310,153 338.38,143.11 371.9,138.85 398.43,137.07"];
	diagram -> cnvkit_main	[_draw_="c 7 -#000000 B 7 322.3 178.63 330.6 170.77 344.11 159.3 358 153 370.54 147.32 384.93 143.53 398.36 141.01 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 398.59 143.46 405.08 139.85 397.76 138.63 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 375 155.6 0 34 7 -diagram ",
		label=diagram,
		lp="375,157.5",
		pos="e,406.57,139.6 322.3,178.63 330.6,170.77 344.11,159.3 358,153 370.54,147.32 384.93,143.53 398.36,141.01"];
	scatter_plot -> cnvkit_main	[_draw_="c 7 -#000000 B 7 386.27 178.66 388.74 171.04 393.38 159.93 401 153 402.94 151.24 405.08 149.65 407.34 148.22 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 408.1 150.6 413.09 145.11 405.76 146.29 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 425.5 155.6 0 49 12 -scatter_plot ",
		label=scatter_plot,
		lp="425.5,157.5",
		pos="e,414.42,144.39 386.27,178.66 388.74,171.04 393.38,159.93 401,153 402.94,151.24 405.08,149.65 407.34,148.22"];
	male_reference -> cns_to_vcf	[_draw_="c 7 -#000000 B 4 642.07 178.82 647.99 163.02 661.09 128.09 668.87 107.36 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 671.14 108.27 671.3 100.86 666.55 106.55 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 693 133.1 0 64 14 -male_reference ",
		label=male_reference,
		lp="693,135",
		pos="e,671.84,99.438 642.07,178.82 647.99,163.02 661.09,128.09 668.87,107.36"];
	male_reference -> cnvkit_main	[_draw_="c 7 -#000000 B 10 614.29 178.51 602.92 174.2 589.45 168.5 578 162 572.2 158.71 572.16 155.54 566 153 542.6 143.34 514.72 138.99 \
491.62 137.1 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 492.01 134.67 484.86 136.62 491.67 139.56 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 610 155.6 0 64 14 -male_reference ",
		label=male_reference,
		lp="610,157.5",
		pos="e,483.35,136.51 614.29,178.51 602.92,174.2 589.45,168.5 578,162 572.2,158.71 572.16,155.54 566,153 542.6,143.34 514.72,138.99 491.62,\
137.1"];
	reference_cnn -> cnvkit_main	[_draw_="c 7 -#000000 B 7 463.43 178.78 460.82 173.96 457.57 167.71 455 162 453.57 158.82 452.15 155.36 450.84 152.04 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 453.22 151.39 448.45 145.71 448.64 153.12 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 484.5 155.6 0 59 13 -reference_cnn ",
		label=reference_cnn,
		lp="484.5,157.5",
		pos="e,447.92,144.29 463.43,178.78 460.82,173.96 457.57,167.71 455,162 453.57,158.82 452.15,155.36 450.84,152.04"];
	segment_filter -> cns_to_vcf	[_draw_="c 7 -#000000 B 7 833.75 178.84 826.42 165.56 810.12 139.32 789 125 772.92 114.1 753.27 106.62 734.84 101.51 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 735.88 99.25 728.49 99.85 734.64 104 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 839.5 133.1 0 59 14 -segment_filter ",
		label=segment_filter,
		lp="839.5,135",
		pos="e,727.03,99.47 833.75,178.84 826.42,165.56 810.12,139.32 789,125 772.92,114.1 753.27,106.62 734.84,101.51"];
	tumor_bam -> cnvkit_main	[_draw_="c 7 -#000000 B 7 542.41 178.67 531.43 169.19 514.5 154.79 511 153 504.87 149.87 498.11 147.28 491.33 145.15 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 492.25 142.87 484.85 143.28 490.89 147.58 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 545 155.6 0 46 9 -tumor_bam ",
		label=tumor_bam,
		lp="545,157.5",
		pos="e,483.39,142.86 542.41,178.67 531.43,169.19 514.5,154.79 511,153 504.87,149.87 498.11,147.28 491.33,145.15"];
	cns_to_vcf -> cnvkit_vcf	[_draw_="c 7 -#000000 B 7 701.26 80.59 715.76 75.77 734.02 69.42 750 63 753.92 61.43 758.02 59.66 762.01 57.88 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 762.73 60.24 768.08 55.11 760.7 55.78 ",
		pos="e,769.46,54.481 701.26,80.59 715.76,75.774 734.02,69.425 750,63 753.92,61.425 758.02,59.66 762.01,57.88"];
	cnvkit_main -> cn_diagram	[_draw_="c 7 -#000000 B 4 445 125.56 445 111.14 445 81.48 445 62.73 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 447.45 62.8 445 55.8 442.55 62.8 ",
		pos="e,445,54.284 445,125.56 445,111.14 445,81.476 445,62.727"];
	cnvkit_main -> tumor_bin_level_ratios	[_draw_="c 7 -#000000 B 7 453.01 125.81 465.37 113.37 490.06 89.21 513 71 518.29 66.8 524.27 62.56 529.86 58.8 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 530.88 61.05 535.38 55.15 528.18 56.97 ",
		pos="e,536.64,54.32 453.01,125.81 465.37,113.37 490.06,89.206 513,71 518.29,66.799 524.27,62.559 529.86,58.795"];
	cnvkit_main -> tumor_target_coverage	[_draw_="c 7 -#000000 B 10 457.29 125.62 479.01 110.84 522.27 81.53 526 80 563.27 64.75 575.66 71.6 615 63 624.04 61.02 633.71 58.75 642.86 \
56.51 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 643.41 58.9 649.62 54.85 642.24 54.14 ",
		pos="e,651.09,54.484 457.29,125.62 479.01,110.84 522.27,81.528 526,80 563.27,64.75 575.66,71.598 615,63 624.04,61.024 633.71,58.746 642.86,\
56.512"];
	cnvkit_main -> cn_scatter_plot	[_draw_="c 7 -#000000 B 7 406.56 127.44 344.03 116.41 216.65 92.44 111 63 104.78 61.27 98.2 59.17 91.95 57.05 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 93.1 54.86 85.69 54.87 91.49 59.49 ",
		pos="e,84.257,54.378 406.56,127.44 344.03,116.41 216.65,92.436 111,63 104.78,61.267 98.198,59.17 91.947,57.05"];
	cnvkit_main -> tumor_segmented_ratios	[_draw_="c 7 -#000000 B 4 419.69 125.56 371.69 109.56 267.48 74.83 214.05 57.02 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 215.09 54.78 207.67 54.89 213.54 59.43 ",
		pos="e,206.24,54.412 419.69,125.56 371.69,109.56 267.48,74.827 214.05,57.017"];
	cnvkit_main -> tumor_antitarget_coverage	[_draw_="c 7 -#000000 B 4 433.88 125.56 413.65 110.21 370.68 77.62 346.49 59.27 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 348.18 57.48 341.13 55.2 345.22 61.38 ",
		pos="e,339.92,54.284 433.88,125.56 413.65,110.21 370.68,77.622 346.49,59.271"];
	cnvkit_main -> cns_to_vcf	[_draw_="c 7 -#000000 B 7 483.39 125.5 512.62 119.08 550.42 110.89 566 108 579.7 105.46 594.41 102.99 608.45 100.76 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 608.6 103.22 615.14 99.71 607.84 98.38 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 581 110.6 0 30 8 -cnr_file ",
		label=cnr_file,
		lp="581,112.5",
		pos="e,616.63,99.476 483.39,125.5 512.62,119.08 550.42,110.89 566,108 579.7,105.46 594.41,102.99 608.45,100.76"];
	cnvkit_main -> cns_to_vcf	[_draw_="c 7 -#000000 B 10 483.45 133.24 513.76 131.78 556.81 127.76 593 117 601.57 114.45 602.63 111.16 611 108 617.05 105.71 623.53 103.61 \
629.96 101.72 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 630.51 104.11 636.58 99.85 629.18 99.39 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 626.5 110.6 0 31 8 -cns_file ",
		label=cns_file,
		lp="626.5,112.5",
		pos="e,638.04,99.443 483.45,133.24 513.76,131.78 556.81,127.76 593,117 601.57,114.45 602.63,111.16 611,108 617.05,105.71 623.53,103.61 \
629.96,101.72"];
}