@prefix LoadListingRequirement: <http://commonwl.org/cwltool#LoadListingRequirement/> .
@prefix CommandLineBinding: <https://w3id.org/cwl/cwl#CommandLineBinding/> .
@prefix xsd:   <http://www.w3.org/2001/XMLSchema#> .
@prefix DockerRequirement: <https://w3id.org/cwl/cwl#DockerRequirement/> .
@prefix Workflow: <https://w3id.org/cwl/cwl#Workflow/> .
@prefix sld:   <https://w3id.org/cwl/salad#> .
@prefix rdfs:  <http://www.w3.org/2000/01/rdf-schema#> .
@prefix CommandOutputBinding: <https://w3id.org/cwl/cwl#CommandOutputBinding/> .
@prefix ns1:   <http://commonwl.org/cwltool#> .
@prefix NetworkAccess: <http://commonwl.org/cwltool#NetworkAccess/> .
@prefix rdf:   <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix Parameter: <https://w3id.org/cwl/cwl#Parameter/> .
@prefix cwl:   <https://w3id.org/cwl/cwl#> .
@prefix ResourceRequirement: <https://w3id.org/cwl/cwl#ResourceRequirement/> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gunzip_known_sites.cwl#known_sites_file>
        cwl:inputBinding  [ CommandLineBinding:position
                          1 ] ;
        sld:type          cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/bwa_mem/read_group>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/readgroup_str> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-haplotype_caller.cwl#gatk_haplotypecaller/threads>
        cwl:default  "2" ;
        sld:type     xsd:string , sld:null .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/picard_dictionary.cwl#picard_markduplicates>
        a                        cwl:CommandLineTool ;
        ns1:original_cwlVersion  "v1.0" ;
        cwl:arguments            ( [ CommandLineBinding:position  2 ;
                                     CommandLineBinding:prefix    "O=" ;
                                     CommandLineBinding:separate  false ;
                                     cwl:valueFrom                "$(inputs.reference_genome.nameroot).dict"
                                   ]
                                 ) ;
        cwl:baseCommand          ( "picard" "CreateSequenceDictionary" ) ;
        cwl:cwlVersion           <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/v1.2> ;
        cwl:hints                [ a       <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/LoadListingRequirement> ;
                                   LoadListingRequirement:loadListing
                                           "deep_listing"
                                 ] ;
        cwl:hints                [ a                             cwl:ResourceRequirement ;
                                   ResourceRequirement:coresMin  4 ;
                                   ResourceRequirement:ramMin    4000
                                 ] ;
        cwl:hints                [ a                            <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/NetworkAccess> ;
                                   NetworkAccess:networkAccess  true
                                 ] ;
        cwl:inputs               <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/picard_dictionary.cwl#picard_markduplicates/reference_genome> ;
        cwl:outputs              <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/picard_dictionary.cwl#picard_markduplicates/dict> ;
        cwl:requirements         [ a                              cwl:ResourceRequirement ;
                                   ResourceRequirement:outdirMin  7500 ;
                                   ResourceRequirement:tmpdirMin  7700
                                 ] ;
        cwl:requirements         [ a  cwl:InlineJavascriptRequirement ] ;
        cwl:requirements         [ a                             cwl:DockerRequirement ;
                                   DockerRequirement:dockerPull  "quay.io/biocontainers/picard:2.18.25--0"
                                 ] .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/bwa-mem.cwl>
        a                        cwl:CommandLineTool ;
        ns1:original_cwlVersion  "v1.0" ;
        cwl:arguments            ( [ CommandLineBinding:position  2 ;
                                     CommandLineBinding:prefix    "-M"
                                   ]
                                   [ CommandLineBinding:position  2 ;
                                     CommandLineBinding:prefix    "-p"
                                   ]
                                 ) ;
        cwl:baseCommand          ( "bwa" "mem" "-M" "-p" ) ;
        cwl:cwlVersion           <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/v1.2> ;
        cwl:hints                [ a       <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/LoadListingRequirement> ;
                                   LoadListingRequirement:loadListing
                                           "deep_listing"
                                 ] ;
        cwl:hints                [ a                            <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/NetworkAccess> ;
                                   NetworkAccess:networkAccess  true
                                 ] ;
        cwl:hints                [ a                             cwl:ResourceRequirement ;
                                   ResourceRequirement:coresMin  4 ;
                                   ResourceRequirement:ramMin    4000
                                 ] ;
        cwl:inputs               <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/bwa-mem.cwl#sample_name> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/bwa-mem.cwl#trimmed_fastq> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/bwa-mem.cwl#reference_genome> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/bwa-mem.cwl#read_group> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/bwa-mem.cwl#threads> ;
        cwl:outputs              <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/bwa-mem.cwl#aligned_sam> ;
        cwl:requirements         [ a  cwl:MultipleInputFeatureRequirement ] ;
        cwl:requirements         [ a                             cwl:DockerRequirement ;
                                   DockerRequirement:dockerPull  "quay.io/biocontainers/bwa:0.7.17--h84994c4_5"
                                 ] ;
        cwl:requirements         [ a  cwl:InlineJavascriptRequirement ] ;
        cwl:requirements         [ a                              cwl:ResourceRequirement ;
                                   ResourceRequirement:outdirMin  10500 ;
                                   ResourceRequirement:tmpdirMin  10700
                                 ] ;
        cwl:stdout               "$(inputs.sample_name).sam" .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-base_recalibration.cwl#gatk-base_recalibration/unzipped_known_sites_file>
        sld:type  cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-base_recalibration_print_reads.cwl#gatk_base_recalibration_print_reads>
        a                        cwl:CommandLineTool ;
        rdfs:label               "gatk-base_recalibration_print_reads" ;
        ns1:original_cwlVersion  "v1.0" ;
        cwl:arguments            ( [ CommandLineBinding:position  0 ;
                                     CommandLineBinding:prefix    "-dt" ;
                                     cwl:valueFrom                "NONE"
                                   ]
                                   [ CommandLineBinding:position  3 ;
                                     CommandLineBinding:prefix    "-o" ;
                                     cwl:valueFrom                "$(inputs.input.nameroot).bqsr.bam"
                                   ]
                                 ) ;
        cwl:baseCommand          ( "java" "-jar" "/usr/GenomeAnalysisTK.jar" "-T" "PrintReads" ) ;
        cwl:cwlVersion           <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/v1.2> ;
        cwl:hints                [ a                            <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/NetworkAccess> ;
                                   NetworkAccess:networkAccess  true
                                 ] ;
        cwl:hints                [ a       <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/LoadListingRequirement> ;
                                   LoadListingRequirement:loadListing
                                           "deep_listing"
                                 ] ;
        cwl:hints                [ a                             cwl:ResourceRequirement ;
                                   ResourceRequirement:coresMin  8 ;
                                   ResourceRequirement:ramMin    8000
                                 ] ;
        cwl:inputs               <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-base_recalibration_print_reads.cwl#gatk_base_recalibration_print_reads/input> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-base_recalibration_print_reads.cwl#gatk_base_recalibration_print_reads/dict> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-base_recalibration_print_reads.cwl#gatk_base_recalibration_print_reads/br_model> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-base_recalibration_print_reads.cwl#gatk_base_recalibration_print_reads/reference_genome> ;
        cwl:outputs              <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-base_recalibration_print_reads.cwl#gatk_base_recalibration_print_reads/bqsr_bam> ;
        cwl:requirements         [ a                             cwl:DockerRequirement ;
                                   DockerRequirement:dockerPull  "broadinstitute/gatk3:3.6-0"
                                 ] ;
        cwl:requirements         [ a            cwl:InitialWorkDirRequirement ;
                                   cwl:listing  [ cwl:entry  "$(inputs.br_model)" ] ;
                                   cwl:listing  [ cwl:entry  "$(inputs.dict)" ] ;
                                   cwl:listing  [ cwl:entry  "$(inputs.reference_genome)" ]
                                 ] ;
        cwl:requirements         [ a  cwl:InlineJavascriptRequirement ] ;
        cwl:requirements         [ a                              cwl:ResourceRequirement ;
                                   ResourceRequirement:outdirMin  7500 ;
                                   ResourceRequirement:tmpdirMin  7700
                                 ] .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-base_recalibration.cwl#gatk-base_recalibration/reference_genome>
        cwl:inputBinding    [ CommandLineBinding:position  1 ;
                              CommandLineBinding:prefix    "-R"
                            ] ;
        cwl:secondaryFiles  []  ;
        sld:type            cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-base_recalibration_print_reads/dict>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/picard_dictionary/dict> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-base_recalibration_print_reads.cwl#gatk_base_recalibration_print_reads/reference_genome>
        cwl:inputBinding    [ CommandLineBinding:position  1 ;
                              CommandLineBinding:prefix    "-R"
                            ] ;
        cwl:secondaryFiles  []  ;
        sld:type            cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-ir.cwl#ir/dict>
        sld:type  cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk3-rtc.cwl#rtc/reference_genome>
        cwl:inputBinding    [ CommandLineBinding:position  1 ;
                              CommandLineBinding:prefix    "-R"
                            ] ;
        cwl:secondaryFiles  []  ;
        sld:type            cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk3-rtc.cwl#rtc/input>
        cwl:inputBinding    [ CommandLineBinding:position  2 ;
                              CommandLineBinding:prefix    "-I"
                            ] ;
        cwl:secondaryFiles  []  ;
        sld:type            cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-haplotype_caller.cwl#gatk_haplotypecaller>
        a                        cwl:CommandLineTool ;
        rdfs:label               "gatk3-haplotypecaller" ;
        ns1:original_cwlVersion  "v1.0" ;
        cwl:arguments            ( [ CommandLineBinding:position  0 ;
                                     CommandLineBinding:prefix    "--num_cpu_threads_per_data_thread" ;
                                     cwl:valueFrom                "$(inputs.threads)"
                                   ]
                                   [ CommandLineBinding:position  0 ;
                                     CommandLineBinding:prefix    "-dt" ;
                                     cwl:valueFrom                "NONE"
                                   ]
                                   [ CommandLineBinding:position  0 ;
                                     CommandLineBinding:prefix    "-rf" ;
                                     cwl:valueFrom                "BadCigar"
                                   ]
                                   [ CommandLineBinding:position  0 ;
                                     CommandLineBinding:prefix    "-ERC" ;
                                     cwl:valueFrom                "GVCF"
                                   ]
                                   [ CommandLineBinding:position  0 ;
                                     CommandLineBinding:prefix    "-variant_index_type" ;
                                     cwl:valueFrom                "LINEAR"
                                   ]
                                   [ CommandLineBinding:position  0 ;
                                     CommandLineBinding:prefix    "-variant_index_parameter" ;
                                     cwl:valueFrom                "128000"
                                   ]
                                   [ CommandLineBinding:position  0 ;
                                     CommandLineBinding:prefix    "-o" ;
                                     cwl:valueFrom                "$(inputs.input.nameroot).vcf.gz"
                                   ]
                                 ) ;
        cwl:baseCommand          ( "java" "-jar" "/usr/GenomeAnalysisTK.jar" "-T" "HaplotypeCaller" "--never_trim_vcf_format_field" ) ;
        cwl:cwlVersion           <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/v1.2> ;
        cwl:hints                [ a                            <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/NetworkAccess> ;
                                   NetworkAccess:networkAccess  true
                                 ] ;
        cwl:hints                [ a                             cwl:ResourceRequirement ;
                                   ResourceRequirement:coresMin  4 ;
                                   ResourceRequirement:ramMin    4000
                                 ] ;
        cwl:hints                [ a       <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/LoadListingRequirement> ;
                                   LoadListingRequirement:loadListing
                                           "deep_listing"
                                 ] ;
        cwl:inputs               <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-haplotype_caller.cwl#gatk_haplotypecaller/dict> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-haplotype_caller.cwl#gatk_haplotypecaller/gqb> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-haplotype_caller.cwl#gatk_haplotypecaller/ploidy> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-haplotype_caller.cwl#gatk_haplotypecaller/reference_genome> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-haplotype_caller.cwl#gatk_haplotypecaller/chromosome> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-haplotype_caller.cwl#gatk_haplotypecaller/threads> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-haplotype_caller.cwl#gatk_haplotypecaller/input> ;
        cwl:outputs              <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-haplotype_caller.cwl#gatk_haplotypecaller/gvcf> ;
        cwl:requirements         [ a  cwl:InlineJavascriptRequirement ] ;
        cwl:requirements         [ a            cwl:InitialWorkDirRequirement ;
                                   cwl:listing  [ cwl:entry  "$(inputs.reference_genome)" ] ;
                                   cwl:listing  [ cwl:entry  "$(inputs.dict)" ]
                                 ] ;
        cwl:requirements         [ a                              cwl:ResourceRequirement ;
                                   ResourceRequirement:outdirMin  7500 ;
                                   ResourceRequirement:tmpdirMin  7700
                                 ] ;
        cwl:requirements         [ a                             cwl:DockerRequirement ;
                                   DockerRequirement:dockerPull  "broadinstitute/gatk3:3.6-0"
                                 ] .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-ir/reference_genome>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/samtools_index/index_fai> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/samtools_sort_bam.cwl#BAM_index>
        a                        cwl:CommandLineTool ;
        rdfs:label               "samtools-bam_sort" ;
        ns1:original_cwlVersion  "v1.0" ;
        cwl:arguments            ( [ CommandLineBinding:position  2 ;
                                     CommandLineBinding:prefix    "-o" ;
                                     cwl:valueFrom                "$(inputs.input.nameroot).sorted.bam"
                                   ]
                                 ) ;
        cwl:baseCommand          ( "samtools" "sort" ) ;
        cwl:cwlVersion           <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/v1.2> ;
        cwl:hints                [ a       <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/LoadListingRequirement> ;
                                   LoadListingRequirement:loadListing
                                           "deep_listing"
                                 ] ;
        cwl:hints                [ a                             cwl:ResourceRequirement ;
                                   ResourceRequirement:coresMin  8 ;
                                   ResourceRequirement:ramMin    8000
                                 ] ;
        cwl:hints                [ a                            <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/NetworkAccess> ;
                                   NetworkAccess:networkAccess  true
                                 ] ;
        cwl:inputs               <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/samtools_sort_bam.cwl#BAM_index/input> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/samtools_sort_bam.cwl#BAM_index/threads> ;
        cwl:outputs              <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/samtools_sort_bam.cwl#BAM_index/sorted_bam> ;
        cwl:requirements         [ a                             cwl:DockerRequirement ;
                                   DockerRequirement:dockerPull  "biocontainers/samtools:1.3.1"
                                 ] ;
        cwl:requirements         [ a  cwl:InlineJavascriptRequirement ] ;
        cwl:requirements         [ a                              cwl:ResourceRequirement ;
                                   ResourceRequirement:outdirMin  7500 ;
                                   ResourceRequirement:tmpdirMin  7700
                                 ] .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-haplotype_caller.cwl#gatk_haplotypecaller/gvcf>
        cwl:outputBinding   [ CommandOutputBinding:glob
                          "*.gz" ] ;
        cwl:secondaryFiles  []  ;
        sld:type            cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-base_recalibration/dict>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/picard_dictionary/dict> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-haplotype_caller.cwl#gatk_haplotypecaller/gqb>
        cwl:inputBinding  [ CommandLineBinding:position
                          12 ] ;
        sld:type          sld:null ;
        sld:type          [ cwl:inputBinding  [ CommandLineBinding:prefix
                                              "--GVCFGQBands" ] ;
                            sld:items         xsd:int ;
                            sld:type          sld:array
                          ] .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-base_recalibration/reference_genome>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/samtools_index/index_fai> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gunzip>
        cwl:in   <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gunzip/reference_file> ;
        cwl:out  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gunzip/unzipped_fasta> ;
        cwl:run  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gunzip.cwl> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk3-rtc.cwl#rtc/dict>
        sld:type  cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/cutadapt-v.1.18.cwl#cutadapt2>
        a                        cwl:CommandLineTool ;
        rdfs:label               "cutadapt" ;
        ns1:original_cwlVersion  "v1.0" ;
        cwl:arguments            ( [ CommandLineBinding:position  4 ;
                                     CommandLineBinding:prefix    "-o" ;
                                     cwl:valueFrom                "$(inputs.raw_sequences[0].basename + \".trimmed.fastq.gz\")"
                                   ]
                                   [ CommandLineBinding:position  3 ;
                                     CommandLineBinding:prefix    "--overlap" ;
                                     cwl:valueFrom                "6"
                                   ]
                                   [ CommandLineBinding:position  1 ;
                                     CommandLineBinding:prefix    "-j" ;
                                     cwl:valueFrom                "0"
                                   ]
                                   [ CommandLineBinding:position  2 ;
                                     CommandLineBinding:prefix    "--error-rate" ;
                                     cwl:valueFrom                "0.2"
                                   ]
                                 ) ;
        cwl:baseCommand          ( "cutadapt" "--interleaved" ) ;
        cwl:cwlVersion           <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/v1.2> ;
        cwl:hints                [ a                             cwl:ResourceRequirement ;
                                   ResourceRequirement:coresMin  4 ;
                                   ResourceRequirement:ramMin    4000
                                 ] ;
        cwl:hints                [ a       <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/LoadListingRequirement> ;
                                   LoadListingRequirement:loadListing
                                           "deep_listing"
                                 ] ;
        cwl:hints                [ a                            <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/NetworkAccess> ;
                                   NetworkAccess:networkAccess  true
                                 ] ;
        cwl:inputs               <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/cutadapt-v.1.18.cwl#cutadapt2/adaptors_file> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/cutadapt-v.1.18.cwl#cutadapt2/raw_sequences> ;
        cwl:outputs              <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/cutadapt-v.1.18.cwl#cutadapt2/trimmed_fastq> ;
        cwl:requirements         [ a                             cwl:DockerRequirement ;
                                   DockerRequirement:dockerPull  "quay.io/biocontainers/cutadapt:1.18--py36h14c3975_1"
                                 ] ;
        cwl:requirements         [ a                              cwl:ResourceRequirement ;
                                   ResourceRequirement:outdirMin  2500 ;
                                   ResourceRequirement:tmpdirMin  2500
                                 ] ;
        cwl:requirements         [ a  cwl:InlineJavascriptRequirement ] .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gunzip/reference_file>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/reference_genome> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/picard_markduplicates.cwl#picard_markduplicates>
        a                        cwl:CommandLineTool ;
        rdfs:label               "picard-MD" ;
        ns1:original_cwlVersion  "v1.0" ;
        cwl:arguments            ( [ CommandLineBinding:position  0 ;
                                     CommandLineBinding:prefix    "OPTICAL_DUPLICATE_PIXEL_DISTANCE=" ;
                                     CommandLineBinding:separate  false ;
                                     cwl:valueFrom                "100"
                                   ]
                                   [ CommandLineBinding:position  0 ;
                                     CommandLineBinding:prefix    "TAGGING_POLICY=" ;
                                     CommandLineBinding:separate  false ;
                                     cwl:valueFrom                "All"
                                   ]
                                   [ CommandLineBinding:position  0 ;
                                     CommandLineBinding:prefix    "CREATE_INDEX=" ;
                                     CommandLineBinding:separate  false ;
                                     cwl:valueFrom                "true"
                                   ]
                                   [ CommandLineBinding:position  0 ;
                                     CommandLineBinding:prefix    "REMOVE_DUPLICATES=" ;
                                     CommandLineBinding:separate  false ;
                                     cwl:valueFrom                "true"
                                   ]
                                   [ CommandLineBinding:position  0 ;
                                     CommandLineBinding:prefix    "TAG_DUPLICATE_SET_MEMBERS=" ;
                                     CommandLineBinding:separate  false ;
                                     cwl:valueFrom                "true"
                                   ]
                                   [ CommandLineBinding:position  0 ;
                                     CommandLineBinding:prefix    "ASSUME_SORT_ORDER=" ;
                                     CommandLineBinding:separate  false ;
                                     cwl:valueFrom                "coordinate"
                                   ]
                                   [ CommandLineBinding:position  1 ;
                                     CommandLineBinding:prefix    "METRICS_FILE=" ;
                                     CommandLineBinding:separate  false ;
                                     cwl:valueFrom                "$(inputs.input.nameroot).metrics.txt"
                                   ]
                                   [ CommandLineBinding:position  3 ;
                                     CommandLineBinding:prefix    "OUTPUT=" ;
                                     CommandLineBinding:separate  false ;
                                     cwl:valueFrom                "$(inputs.input.nameroot).md.bam"
                                   ]
                                 ) ;
        cwl:baseCommand          ( "picard" "MarkDuplicates" ) ;
        cwl:cwlVersion           <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/v1.2> ;
        cwl:hints                [ a       <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/LoadListingRequirement> ;
                                   LoadListingRequirement:loadListing
                                           "deep_listing"
                                 ] ;
        cwl:hints                [ a                             cwl:ResourceRequirement ;
                                   ResourceRequirement:coresMin  4 ;
                                   ResourceRequirement:ramMin    4000
                                 ] ;
        cwl:hints                [ a                            <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/NetworkAccess> ;
                                   NetworkAccess:networkAccess  true
                                 ] ;
        cwl:inputs               <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/picard_markduplicates.cwl#picard_markduplicates/input> ;
        cwl:outputs              <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/picard_markduplicates.cwl#picard_markduplicates/md_bam> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/picard_markduplicates.cwl#picard_markduplicates/output_metrics> ;
        cwl:requirements         [ a                             cwl:DockerRequirement ;
                                   DockerRequirement:dockerPull  "quay.io/biocontainers/picard:2.18.25--0"
                                 ] ;
        cwl:requirements         [ a  cwl:InlineJavascriptRequirement ] ;
        cwl:requirements         [ a                              cwl:ResourceRequirement ;
                                   ResourceRequirement:outdirMin  7500 ;
                                   ResourceRequirement:tmpdirMin  7700
                                 ] .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/samtools_sort_bam.cwl#BAM_index/sorted_bam>
        cwl:outputBinding  [ CommandOutputBinding:glob
                          "*.sorted.bam" ] ;
        sld:type           cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-base_recalibration/unzipped_known_sites_file>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/unzipped_known_sites/unzipped_known_sites_file> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/picard_markduplicates/input>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/samtools_sort/sorted_bam> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-base_recalibration.cwl#gatk-base_recalibration/input>
        cwl:inputBinding    [ CommandLineBinding:position  2 ;
                              CommandLineBinding:prefix    "-I"
                            ] ;
        cwl:secondaryFiles  []  ;
        sld:type            cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-haplotype_caller.cwl#gatk_haplotypecaller/reference_genome>
        cwl:inputBinding    [ CommandLineBinding:position  1 ;
                              CommandLineBinding:prefix    "-R"
                            ] ;
        cwl:secondaryFiles  []  ;
        sld:type            cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/picard_markduplicates.cwl#picard_markduplicates/input>
        cwl:inputBinding  [ CommandLineBinding:position  2 ;
                            CommandLineBinding:prefix    "INPUT=" ;
                            CommandLineBinding:separate  false
                          ] ;
        sld:type          cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/cutadapt-v.1.18.cwl#cutadapt2/adaptors_file>
        cwl:inputBinding  [ CommandLineBinding:position  10 ;
                            CommandLineBinding:prefix    "-a"
                          ] ;
        sld:type          cwl:File , sld:null .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/bwa-mem.cwl#read_group>
        cwl:default       "@RG\\\\tID:H947YADXX\\\\tSM:NA12878\\\\tPL:ILLUMINA" ;
        cwl:inputBinding  [ CommandLineBinding:position  2 ;
                            CommandLineBinding:prefix    "-R"
                          ] ;
        sld:type          xsd:string .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/bwa_mem/reference_genome>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/bwa_index/output> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk_haplotype_caller/dict>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/picard_dictionary/dict> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-base_recalibration.cwl#gatk-base_recalibration/dict>
        sld:type  cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/unzipped_known_sites>
        cwl:in   <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/unzipped_known_sites/known_sites_file> ;
        cwl:out  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/unzipped_known_sites/unzipped_known_sites_file> ;
        cwl:run  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gunzip_known_sites.cwl> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/fastq_files>
        sld:type  [ sld:items  cwl:File ;
                    sld:type   sld:array
                  ] .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/samtools_index.cwl#fastq_index>
        a                        cwl:CommandLineTool ;
        rdfs:label               "samtools-faidx" ;
        ns1:original_cwlVersion  "v1.0" ;
        cwl:baseCommand          ( "samtools" "faidx" ) ;
        cwl:cwlVersion           <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/v1.2> ;
        cwl:hints                [ a       <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/LoadListingRequirement> ;
                                   LoadListingRequirement:loadListing
                                           "deep_listing"
                                 ] ;
        cwl:hints                [ a                            <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/NetworkAccess> ;
                                   NetworkAccess:networkAccess  true
                                 ] ;
        cwl:hints                [ a                             cwl:ResourceRequirement ;
                                   ResourceRequirement:coresMin  8 ;
                                   ResourceRequirement:ramMin    8000
                                 ] ;
        cwl:inputs               <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/samtools_index.cwl#fastq_index/input> ;
        cwl:outputs              <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/samtools_index.cwl#fastq_index/index_fai> ;
        cwl:requirements         [ a                             cwl:DockerRequirement ;
                                   DockerRequirement:dockerPull  "biocontainers/samtools:1.3.1"
                                 ] ;
        cwl:requirements         [ a                              cwl:ResourceRequirement ;
                                   ResourceRequirement:outdirMin  7500 ;
                                   ResourceRequirement:tmpdirMin  7700
                                 ] ;
        cwl:requirements         [ a            cwl:InitialWorkDirRequirement ;
                                   cwl:listing  [ cwl:entry  "$(inputs.input)" ]
                                 ] ;
        cwl:requirements         [ a  cwl:InlineJavascriptRequirement ] .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/cutadapt2>
        cwl:in   <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/cutadapt2/raw_sequences> ;
        cwl:out  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/cutadapt2/trimmed_fastq> ;
        cwl:run  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/cutadapt-v.1.18.cwl> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/picard_markduplicates.cwl#picard_markduplicates/output_metrics>
        cwl:outputBinding  [ CommandOutputBinding:glob
                          "*.metrics.txt" ] ;
        sld:type           cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/bwa_mem/sample_name>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/sample_name> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/known_indels_file>
        sld:type  cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/bwa_mem>
        cwl:in   <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/bwa_mem/trimmed_fastq> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/bwa_mem/sample_name> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/bwa_mem/reference_genome> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/bwa_mem/read_group> ;
        cwl:out  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/bwa_mem/aligned_sam> ;
        cwl:run  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/bwa-mem.cwl> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/chromosome>
        sld:type  xsd:string , sld:null .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-ir.cwl#ir/rtc_intervals>
        cwl:inputBinding  [ CommandLineBinding:position  3 ;
                            CommandLineBinding:prefix    "-targetIntervals"
                          ] ;
        sld:type          cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/picard_markduplicates>
        rdfs:label  "picard-MD" ;
        cwl:in      <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/picard_markduplicates/input> ;
        cwl:out     <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/picard_markduplicates/md_bam> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/picard_markduplicates/output_metrics> ;
        cwl:run     <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/picard_markduplicates.cwl> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-base_recalibration_print_reads>
        rdfs:label  "gatk-base_recalibration_print_reads" ;
        cwl:in      <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-base_recalibration_print_reads/br_model> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-base_recalibration_print_reads/input> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-base_recalibration_print_reads/reference_genome> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-base_recalibration_print_reads/dict> ;
        cwl:out     <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-base_recalibration_print_reads/bqsr_bam> ;
        cwl:run     <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-base_recalibration_print_reads.cwl> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/metrics>
        cwl:outputSource  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/picard_markduplicates/output_metrics> ;
        sld:type          cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/bwa-mem.cwl#threads>
        rdfs:comment      "-t INT        number of threads [1]" ;
        cwl:default       "2" ;
        cwl:inputBinding  [ CommandLineBinding:position  1 ;
                            CommandLineBinding:prefix    "-t"
                          ] ;
        sld:type          xsd:string , sld:null .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/readgroup_str>
        sld:type  xsd:string .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/samtools_index.cwl#fastq_index/input>
        cwl:inputBinding  [ CommandLineBinding:position
                          1 ] ;
        sld:type          cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-ir/dict>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/picard_dictionary/dict> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-base_recalibration.cwl#gatk-base_recalibration/known_indels_file>
        sld:type  cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-base_recalibration/known_indels_file>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/known_indels_file> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-ir.cwl#ir>
        a                        cwl:CommandLineTool ;
        rdfs:label               "ir" ;
        ns1:original_cwlVersion  "v1.0" ;
        cwl:arguments            ( [ CommandLineBinding:position  5 ;
                                     CommandLineBinding:prefix    "-dt" ;
                                     cwl:valueFrom                "NONE"
                                   ]
                                   [ CommandLineBinding:position  6 ;
                                     CommandLineBinding:prefix    "--maxReadsForRealignment" ;
                                     cwl:valueFrom                "200000"
                                   ]
                                   [ CommandLineBinding:position  10 ;
                                     CommandLineBinding:prefix    "-o" ;
                                     cwl:valueFrom                "$(inputs.input.nameroot).realigned.bam"
                                   ]
                                 ) ;
        cwl:baseCommand          ( "java" "-jar" "/usr/GenomeAnalysisTK.jar" "-T" "IndelRealigner" ) ;
        cwl:cwlVersion           <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/v1.2> ;
        cwl:hints                [ a                             cwl:ResourceRequirement ;
                                   ResourceRequirement:coresMin  8 ;
                                   ResourceRequirement:ramMin    8000
                                 ] ;
        cwl:hints                [ a                            <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/NetworkAccess> ;
                                   NetworkAccess:networkAccess  true
                                 ] ;
        cwl:hints                [ a       <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/LoadListingRequirement> ;
                                   LoadListingRequirement:loadListing
                                           "deep_listing"
                                 ] ;
        cwl:inputs               <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-ir.cwl#ir/dict> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-ir.cwl#ir/input> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-ir.cwl#ir/reference_genome> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-ir.cwl#ir/rtc_intervals> ;
        cwl:outputs              <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-ir.cwl#ir/realigned_bam> ;
        cwl:requirements         [ a            cwl:InitialWorkDirRequirement ;
                                   cwl:listing  [ cwl:entry  "$(inputs.dict)" ] ;
                                   cwl:listing  [ cwl:entry  "$(inputs.reference_genome)" ]
                                 ] ;
        cwl:requirements         [ a                             cwl:DockerRequirement ;
                                   DockerRequirement:dockerPull  "broadinstitute/gatk3:3.6-0"
                                 ] ;
        cwl:requirements         [ a                              cwl:ResourceRequirement ;
                                   ResourceRequirement:outdirMin  7500 ;
                                   ResourceRequirement:tmpdirMin  7700
                                 ] ;
        cwl:requirements         [ a  cwl:InlineJavascriptRequirement ] .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/bwa_index>
        cwl:in   <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/bwa_index/reference_genome> ;
        cwl:out  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/bwa_index/output> ;
        cwl:run  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/bwa-index.cwl> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-base_recalibration_print_reads.cwl#gatk_base_recalibration_print_reads/bqsr_bam>
        cwl:outputBinding   [ CommandOutputBinding:glob
                          "$(inputs.input.nameroot).bqsr.bam" ] ;
        cwl:secondaryFiles  []  ;
        sld:type            cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/bwa-index.cwl#block_size>
        cwl:inputBinding  [ CommandLineBinding:position  2 ;
                            CommandLineBinding:prefix    "-b"
                          ] ;
        sld:type          xsd:int , sld:null .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk_haplotype_caller>
        rdfs:label  "gatk-haplotype_caller" ;
        cwl:in      <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk_haplotype_caller/chromosome> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk_haplotype_caller/input> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk_haplotype_caller/reference_genome> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk_haplotype_caller/dict> ;
        cwl:out     <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk_haplotype_caller/gvcf> ;
        cwl:run     <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-haplotype_caller.cwl> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/reference_genome>
        sld:type  [ sld:items  cwl:File ;
                    sld:type   sld:array
                  ] .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-ir>
        rdfs:label  "gatk-ir" ;
        cwl:in      <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-ir/input> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-ir/rtc_intervals> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-ir/dict> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-ir/reference_genome> ;
        cwl:out     <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-ir/realigned_bam> ;
        cwl:run     <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-ir.cwl> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-base_recalibration/input>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-ir/realigned_bam> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-base_recalibration_print_reads.cwl#gatk_base_recalibration_print_reads/input>
        cwl:inputBinding    [ CommandLineBinding:position  2 ;
                              CommandLineBinding:prefix    "-I"
                            ] ;
        cwl:secondaryFiles  []  ;
        sld:type            cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/bwa-index.cwl#output>
        cwl:outputBinding   [ CommandOutputBinding:glob
                          "*.fa" ] ;
        cwl:secondaryFiles  []  ;
        cwl:secondaryFiles  []  ;
        cwl:secondaryFiles  []  ;
        cwl:secondaryFiles  []  ;
        cwl:secondaryFiles  []  ;
        sld:type            cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk3-rtc/known_indels>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/known_indels_file> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-base_recalibration.cwl#gatk-base_recalibration>
        a                        cwl:CommandLineTool ;
        rdfs:label               "gatk3-base_recalibration" ;
        ns1:original_cwlVersion  "v1.0" ;
        cwl:arguments            ( [ CommandLineBinding:position  0 ;
                                     CommandLineBinding:prefix    "-dt" ;
                                     cwl:valueFrom                "NONE"
                                   ]
                                   [ CommandLineBinding:position  0 ;
                                     CommandLineBinding:prefix    "-nct" ;
                                     cwl:valueFrom                "$(inputs.threads)"
                                   ]
                                   [ CommandLineBinding:position  0 ;
                                     CommandLineBinding:prefix    "--knownSites" ;
                                     cwl:valueFrom                "$(inputs.known_indels_file)"
                                   ]
                                   [ CommandLineBinding:position  0 ;
                                     CommandLineBinding:prefix    "--knownSites" ;
                                     cwl:valueFrom                "$(inputs.unzipped_known_sites_file)"
                                   ]
                                   [ CommandLineBinding:position  3 ;
                                     CommandLineBinding:prefix    "-o" ;
                                     cwl:valueFrom                "$(inputs.input.nameroot).recalibrated.grp"
                                   ]
                                 ) ;
        cwl:baseCommand          ( "java" "-jar" "/usr/GenomeAnalysisTK.jar" "-T" "BaseRecalibrator" ) ;
        cwl:cwlVersion           <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/v1.2> ;
        cwl:hints                [ a                             cwl:ResourceRequirement ;
                                   ResourceRequirement:coresMin  4 ;
                                   ResourceRequirement:ramMin    4000
                                 ] ;
        cwl:hints                [ a                            <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/NetworkAccess> ;
                                   NetworkAccess:networkAccess  true
                                 ] ;
        cwl:hints                [ a       <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/LoadListingRequirement> ;
                                   LoadListingRequirement:loadListing
                                           "deep_listing"
                                 ] ;
        cwl:inputs               <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-base_recalibration.cwl#gatk-base_recalibration/dict> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-base_recalibration.cwl#gatk-base_recalibration/threads> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-base_recalibration.cwl#gatk-base_recalibration/unzipped_known_sites_file> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-base_recalibration.cwl#gatk-base_recalibration/reference_genome> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-base_recalibration.cwl#gatk-base_recalibration/input> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-base_recalibration.cwl#gatk-base_recalibration/known_indels_file> ;
        cwl:outputs              <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-base_recalibration.cwl#gatk-base_recalibration/br_model> ;
        cwl:requirements         [ a            cwl:InitialWorkDirRequirement ;
                                   cwl:listing  [ cwl:entry  "$(inputs.dict)" ] ;
                                   cwl:listing  [ cwl:entry  "$(inputs.reference_genome)" ]
                                 ] ;
        cwl:requirements         [ a  cwl:InlineJavascriptRequirement ] ;
        cwl:requirements         [ a                              cwl:ResourceRequirement ;
                                   ResourceRequirement:outdirMin  7500 ;
                                   ResourceRequirement:tmpdirMin  7700
                                 ] ;
        cwl:requirements         [ a                             cwl:DockerRequirement ;
                                   DockerRequirement:dockerPull  "broadinstitute/gatk3:3.6-0"
                                 ] .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk_haplotype_caller/reference_genome>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/samtools_index/index_fai> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/picard_dictionary.cwl#picard_markduplicates/dict>
        cwl:outputBinding  [ CommandOutputBinding:glob
                          "*.dict" ] ;
        sld:type           cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/sample_name>
        sld:type  xsd:string .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-ir/input>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/picard_markduplicates/md_bam> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/cutadapt-v.1.18.cwl#cutadapt2/raw_sequences>
        cwl:inputBinding  [ CommandLineBinding:position  20 ;
                            CommandLineBinding:prefix    "" ;
                            CommandLineBinding:separate  false
                          ] ;
        sld:type          [ sld:items  cwl:File ;
                            sld:type   sld:array
                          ] .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk3-rtc/reference_genome>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/samtools_index/index_fai> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-base_recalibration_print_reads.cwl#gatk_base_recalibration_print_reads/br_model>
        cwl:inputBinding  [ CommandLineBinding:position  4 ;
                            CommandLineBinding:prefix    "-BQSR"
                          ] ;
        sld:type          cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk3-rtc>
        rdfs:label  "gatk3-rtc" ;
        cwl:in      <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk3-rtc/dict> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk3-rtc/input> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk3-rtc/reference_genome> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk3-rtc/known_indels> ;
        cwl:out     <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk3-rtc/rtc_intervals_file> ;
        cwl:run     <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk3-rtc.cwl> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk3-rtc.cwl#rtc/rtc_intervals_name>
        cwl:default  "rtc_intervals.list" ;
        sld:type     xsd:string , sld:null .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/picard_markduplicates.cwl#picard_markduplicates/md_bam>
        cwl:outputBinding   [ CommandOutputBinding:glob
                          "*.md.bam" ] ;
        cwl:secondaryFiles  []  ;
        sld:type            cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/samtools_index/input>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gunzip/unzipped_fasta> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/cutadapt-v.1.18.cwl#cutadapt2/trimmed_fastq>
        cwl:outputBinding  [ CommandOutputBinding:glob
                          "*.trimmed.fastq.gz" ] ;
        sld:type           cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-ir.cwl#ir/realigned_bam>
        cwl:outputBinding   [ CommandOutputBinding:glob
                          "*.realigned.bam" ] ;
        cwl:secondaryFiles  []  ;
        sld:type            cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-ir.cwl#ir/reference_genome>
        cwl:inputBinding    [ CommandLineBinding:position  1 ;
                              CommandLineBinding:prefix    "-R"
                            ] ;
        cwl:secondaryFiles  []  ;
        sld:type            cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk3-rtc.cwl#rtc/known_indels>
        cwl:inputBinding  [ CommandLineBinding:position  4 ;
                            CommandLineBinding:prefix    "--known"
                          ] ;
        sld:type          cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/unzipped_known_sites/known_sites_file>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/known_sites_file> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-base_recalibration_print_reads/reference_genome>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/samtools_index/index_fai> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gunzip.cwl>
        a                        cwl:CommandLineTool ;
        ns1:original_cwlVersion  "v1.0" ;
        cwl:arguments            ( "-c" "-v" ) ;
        cwl:baseCommand          ( "gunzip" ) ;
        cwl:cwlVersion           <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/v1.2> ;
        cwl:hints                [ a       <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/LoadListingRequirement> ;
                                   LoadListingRequirement:loadListing
                                           "deep_listing"
                                 ] ;
        cwl:hints                [ a                             cwl:ResourceRequirement ;
                                   ResourceRequirement:coresMin  2 ;
                                   ResourceRequirement:ramMin    5000
                                 ] ;
        cwl:hints                [ a                            <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/NetworkAccess> ;
                                   NetworkAccess:networkAccess  true
                                 ] ;
        cwl:inputs               <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gunzip.cwl#reference_file> ;
        cwl:outputs              <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gunzip.cwl#unzipped_fasta> ;
        cwl:requirements         [ a  cwl:InlineJavascriptRequirement ] ;
        cwl:requirements         [ a                              cwl:ResourceRequirement ;
                                   ResourceRequirement:outdirMin  7500 ;
                                   ResourceRequirement:tmpdirMin  7500
                                 ] ;
        cwl:requirements         [ a                             cwl:DockerRequirement ;
                                   DockerRequirement:dockerPull  "jlaitinen/lftpalpine"
                                 ] ;
        cwl:stdout               "$(inputs.reference_file[0].nameroot)" .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/samtools_index>
        cwl:in   <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/samtools_index/input> ;
        cwl:out  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/samtools_index/index_fai> ;
        cwl:run  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/samtools_index.cwl> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/bwa-mem.cwl#reference_genome>
        cwl:inputBinding    [ CommandLineBinding:position
                          3 ] ;
        cwl:secondaryFiles  []  ;
        cwl:secondaryFiles  []  ;
        cwl:secondaryFiles  []  ;
        cwl:secondaryFiles  []  ;
        cwl:secondaryFiles  []  ;
        sld:type            cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gunzip_known_sites.cwl>
        a                        cwl:CommandLineTool ;
        ns1:original_cwlVersion  "v1.0" ;
        cwl:arguments            ( "-c" ) ;
        cwl:baseCommand          ( "gunzip" ) ;
        cwl:cwlVersion           <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/v1.2> ;
        cwl:hints                [ a       <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/LoadListingRequirement> ;
                                   LoadListingRequirement:loadListing
                                           "deep_listing"
                                 ] ;
        cwl:hints                [ a                            <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/NetworkAccess> ;
                                   NetworkAccess:networkAccess  true
                                 ] ;
        cwl:inputs               <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gunzip_known_sites.cwl#known_sites_file> ;
        cwl:outputs              <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gunzip_known_sites.cwl#unzipped_known_sites_file> ;
        cwl:requirements         [ a  cwl:InlineJavascriptRequirement ] ;
        cwl:requirements         [ a                             cwl:DockerRequirement ;
                                   DockerRequirement:dockerPull  "jlaitinen/lftpalpine"
                                 ] ;
        cwl:requirements         [ a                              cwl:ResourceRequirement ;
                                   ResourceRequirement:coresMin   2 ;
                                   ResourceRequirement:outdirMin  12500 ;
                                   ResourceRequirement:ramMin     2000 ;
                                   ResourceRequirement:tmpdirMin  12500
                                 ] ;
        cwl:stdout               "$(inputs.known_sites_file.nameroot)" .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/cutadapt2/raw_sequences>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/fastq_files> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-base_recalibration_print_reads.cwl#gatk_base_recalibration_print_reads/dict>
        sld:type  cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-base_recalibration.cwl#gatk-base_recalibration/threads>
        sld:type  xsd:string , sld:null .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/picard_dictionary.cwl#picard_markduplicates/reference_genome>
        cwl:inputBinding  [ CommandLineBinding:position  1 ;
                            CommandLineBinding:prefix    "R=" ;
                            CommandLineBinding:separate  false
                          ] ;
        sld:type          cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-ir.cwl#ir/input>
        cwl:inputBinding    [ CommandLineBinding:position  2 ;
                              CommandLineBinding:prefix    "-I"
                            ] ;
        cwl:secondaryFiles  []  ;
        sld:type            cwl:File ;
        sld:type            [ sld:items  cwl:File ;
                              sld:type   sld:array
                            ] .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-haplotype_caller.cwl#gatk_haplotypecaller/dict>
        sld:type  cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/bwa-mem.cwl#sample_name>
        sld:type  xsd:string .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/bwa-index.cwl#algorithm>
        rdfs:comment      "BWT construction algorithm: bwtsw or is (Default: auto)\n" ;
        cwl:inputBinding  [ CommandLineBinding:prefix
                          "-a" ] ;
        sld:type          xsd:string , sld:null .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk3-rtc.cwl#rtc/rtc_intervals_file>
        cwl:outputBinding  [ CommandOutputBinding:glob
                          "*.list" ] ;
        sld:type           cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gunzip.cwl#reference_file>
        cwl:inputBinding  [ CommandLineBinding:position
                          2 ] ;
        sld:type          [ sld:items  cwl:File ;
                            sld:type   sld:array
                          ] .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/picard_dictionary/reference_genome>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gunzip/unzipped_fasta> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk3-rtc.cwl#rtc>
        a                        cwl:CommandLineTool ;
        rdfs:label               "rtc" ;
        ns1:original_cwlVersion  "v1.0" ;
        cwl:arguments            ( [ CommandLineBinding:position  5 ;
                                     CommandLineBinding:prefix    "-dt" ;
                                     cwl:valueFrom                "NONE"
                                   ]
                                   [ CommandLineBinding:position  3 ;
                                     CommandLineBinding:prefix    "-o" ;
                                     cwl:valueFrom                "$(inputs.rtc_intervals_name)"
                                   ]
                                 ) ;
        cwl:baseCommand          ( "java" "-jar" "/usr/GenomeAnalysisTK.jar" "-T" "RealignerTargetCreator" ) ;
        cwl:cwlVersion           <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/v1.2> ;
        cwl:hints                [ a                             cwl:ResourceRequirement ;
                                   ResourceRequirement:coresMin  4 ;
                                   ResourceRequirement:ramMin    8000
                                 ] ;
        cwl:hints                [ a       <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/LoadListingRequirement> ;
                                   LoadListingRequirement:loadListing
                                           "deep_listing"
                                 ] ;
        cwl:hints                [ a                            <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/NetworkAccess> ;
                                   NetworkAccess:networkAccess  true
                                 ] ;
        cwl:inputs               <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk3-rtc.cwl#rtc/reference_genome> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk3-rtc.cwl#rtc/input> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk3-rtc.cwl#rtc/rtc_intervals_name> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk3-rtc.cwl#rtc/known_indels> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk3-rtc.cwl#rtc/dict> ;
        cwl:outputs              <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk3-rtc.cwl#rtc/rtc_intervals_file> ;
        cwl:requirements         [ a                              cwl:ResourceRequirement ;
                                   ResourceRequirement:outdirMin  12500 ;
                                   ResourceRequirement:tmpdirMin  12500
                                 ] ;
        cwl:requirements         [ a            cwl:InitialWorkDirRequirement ;
                                   cwl:listing  [ cwl:entry  "$(inputs.reference_genome)" ] ;
                                   cwl:listing  [ cwl:entry  "$(inputs.dict)" ] ;
                                   cwl:listing  [ cwl:entry  "$(inputs.known_indels)" ]
                                 ] ;
        cwl:requirements         [ a  cwl:InlineJavascriptRequirement ] ;
        cwl:requirements         [ a                             cwl:DockerRequirement ;
                                   DockerRequirement:dockerPull  "broadinstitute/gatk3:3.6-0"
                                 ] .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/samtools_sort/input>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/bwa_mem/aligned_sam> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/bwa_index/reference_genome>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gunzip/unzipped_fasta> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/samtools_sort_bam.cwl#BAM_index/threads>
        cwl:default       8 ;
        cwl:inputBinding  [ CommandLineBinding:position  1 ;
                            CommandLineBinding:prefix    "--threads"
                          ] ;
        sld:type          xsd:string , sld:null .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-haplotype_caller.cwl#gatk_haplotypecaller/ploidy>
        cwl:inputBinding  [ CommandLineBinding:position  5 ;
                            CommandLineBinding:prefix    "-ploidy"
                          ] ;
        sld:type          xsd:int , sld:null .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-haplotype_caller.cwl#gatk_haplotypecaller/input>
        cwl:inputBinding    [ CommandLineBinding:position  2 ;
                              CommandLineBinding:prefix    "-I"
                            ] ;
        cwl:secondaryFiles  []  ;
        sld:type            cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gvcf>
        cwl:outputSource  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk_haplotype_caller/gvcf> ;
        sld:type          cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-haplotype_caller.cwl#gatk_haplotypecaller/chromosome>
        cwl:inputBinding  [ CommandLineBinding:position  3 ;
                            CommandLineBinding:prefix    "-L"
                          ] ;
        sld:type          xsd:string , sld:null .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/bwa-index.cwl>
        a                        cwl:CommandLineTool ;
        ns1:original_cwlVersion  "v1.0" ;
        cwl:baseCommand          ( "bwa" "index" ) ;
        cwl:cwlVersion           <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/v1.2> ;
        cwl:hints                [ a       <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/LoadListingRequirement> ;
                                   LoadListingRequirement:loadListing
                                           "deep_listing"
                                 ] ;
        cwl:hints                [ a                             cwl:ResourceRequirement ;
                                   ResourceRequirement:coresMin  1 ;
                                   ResourceRequirement:ramMin    4000
                                 ] ;
        cwl:hints                [ a                            <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/NetworkAccess> ;
                                   NetworkAccess:networkAccess  true
                                 ] ;
        cwl:inputs               <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/bwa-index.cwl#reference_genome> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/bwa-index.cwl#algorithm> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/bwa-index.cwl#block_size> ;
        cwl:outputs              <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/bwa-index.cwl#output> ;
        cwl:requirements         [ a            cwl:InitialWorkDirRequirement ;
                                   cwl:listing  [ cwl:entry  "$(inputs.reference_genome)" ]
                                 ] ;
        cwl:requirements         [ a                              cwl:ResourceRequirement ;
                                   ResourceRequirement:outdirMin  10500 ;
                                   ResourceRequirement:tmpdirMin  10500
                                 ] ;
        cwl:requirements         [ a                             cwl:DockerRequirement ;
                                   DockerRequirement:dockerPull  "quay.io/biocontainers/bwa:0.7.17--h84994c4_5"
                                 ] ;
        cwl:requirements         [ a  cwl:InlineJavascriptRequirement ] .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gunzip_known_sites.cwl#unzipped_known_sites_file>
        cwl:outputBinding  [ CommandOutputBinding:glob
                          "$(inputs.known_sites_file.nameroot)" ] ;
        sld:type           cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/bwa-mem.cwl#trimmed_fastq>
        cwl:inputBinding  [ CommandLineBinding:position
                          4 ] ;
        sld:type          cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/known_sites_file>
        sld:type  cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/picard_dictionary>
        cwl:in   <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/picard_dictionary/reference_genome> ;
        cwl:out  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/picard_dictionary/dict> ;
        cwl:run  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/picard_dictionary.cwl> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/bwa-index.cwl#reference_genome>
        cwl:inputBinding  [ CommandLineBinding:position
                          4 ] ;
        sld:type          cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/bwa-mem.cwl#aligned_sam>
        cwl:outputBinding  [ CommandOutputBinding:glob
                          "*.sam" ] ;
        sld:type           cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk3-rtc/dict>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/picard_dictionary/dict> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-base_recalibration_print_reads/input>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-ir/realigned_bam> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/bwa_mem/trimmed_fastq>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/cutadapt2/trimmed_fastq> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk3-rtc/input>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/picard_markduplicates/md_bam> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk_haplotype_caller/chromosome>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/chromosome> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-base_recalibration>
        rdfs:label  "gatk-base_recalibration" ;
        cwl:in      <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-base_recalibration/input> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-base_recalibration/known_indels_file> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-base_recalibration/unzipped_known_sites_file> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-base_recalibration/reference_genome> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-base_recalibration/dict> ;
        cwl:out     <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-base_recalibration/br_model> ;
        cwl:run     <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-base_recalibration.cwl> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/samtools_sort_bam.cwl#BAM_index/input>
        cwl:inputBinding  [ CommandLineBinding:position
                          2 ] ;
        sld:type          cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gunzip.cwl#unzipped_fasta>
        Parameter:streamable  true ;
        cwl:outputBinding     [ CommandOutputBinding:glob
                          "$(inputs.reference_file[0].nameroot)" ] ;
        sld:type              cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/samtools_index.cwl#fastq_index/index_fai>
        cwl:outputBinding   [ CommandOutputBinding:glob
                          "*.fa" ] ;
        cwl:secondaryFiles  []  ;
        sld:type            cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-base_recalibration_print_reads/br_model>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-base_recalibration/br_model> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk_haplotype_caller/input>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-base_recalibration_print_reads/bqsr_bam> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-ir/rtc_intervals>
        cwl:source  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk3-rtc/rtc_intervals_file> .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/gatk-base_recalibration.cwl#gatk-base_recalibration/br_model>
        cwl:outputBinding  [ CommandOutputBinding:glob
                          "*.grp" ] ;
        sld:type           cwl:File .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect>
        a                        cwl:Workflow ;
        rdfs:label               "RD_Connect" ;
        ns1:original_cwlVersion  "v1.0" ;
        Workflow:steps           <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-ir> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/samtools_sort> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/bwa_index> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/bwa_mem> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/picard_markduplicates> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/cutadapt2> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/unzipped_known_sites> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-base_recalibration_print_reads> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk3-rtc> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gunzip> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/picard_dictionary> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk-base_recalibration> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gatk_haplotype_caller> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/samtools_index> ;
        cwl:cwlVersion           <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/v1.2> ;
        cwl:hints                [ a       <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/LoadListingRequirement> ;
                                   LoadListingRequirement:loadListing
                                           "deep_listing"
                                 ] ;
        cwl:hints                [ a                            <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/NetworkAccess> ;
                                   NetworkAccess:networkAccess  true
                                 ] ;
        cwl:inputs               <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/reference_genome> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/known_indels_file> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/chromosome> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/fastq_files> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/readgroup_str> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/sample_name> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/known_sites_file> ;
        cwl:outputs              <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/gvcf> , <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/metrics> ;
        cwl:requirements         [ a  cwl:MultipleInputFeatureRequirement ] .

<https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/samtools_sort>
        cwl:in   <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/samtools_sort/input> ;
        cwl:out  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/workflow_localfiles.cwl#rd_connect/samtools_sort/sorted_bam> ;
        cwl:run  <https://w3id.org/cwl/view/git/eaf7d66d3441740d8bd81a170a0d930d2a268a4c/cwl-workflows/demonstrator/samtools_sort_bam.cwl> .
