digraph workflow {
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		bb="0,0,1399,233",
		bgcolor="#eeeeee",
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	edge [arrowsize=0.7,
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		fontcolor=black,
		fontname=Helvetica,
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	subgraph cluster_inputs {
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			rects="578,178.5,632,197.5",
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			rects="345,178.5,421,197.5",
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		bait_intervals	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 636.5 178.5 636.5 197.5 719.5 197.5 719.5 178.5 ",
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			rects="636.5,178.5,719.5,197.5",
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			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 749 185.5 0 34 6 -access ",
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		normal_cram	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 492.5 178.5 492.5 197.5 573.5 197.5 573.5 178.5 ",
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			rects="492.5,178.5,573.5,197.5",
			width=1.125];
		diagram	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 778.5 178.5 778.5 197.5 835.5 197.5 835.5 178.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 807 185.5 0 41 7 -diagram ",
			fillcolor="#94DDF4",
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			label=diagram,
			pos="807,188",
			rects="778.5,178.5,835.5,197.5",
			width=0.79167];
		scatter_plot	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 840 178.5 840 197.5 914 197.5 914 178.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 877 185.5 0 58 12 -scatter_plot ",
			fillcolor="#94DDF4",
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			label=scatter_plot,
			pos="877,188",
			rects="840,178.5,914,197.5",
			width=1.0278];
		drop_low_coverage	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 918.5 178.5 918.5 197.5 1029.5 197.5 1029.5 178.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 974 185.5 0 95 17 -drop_low_coverage ",
			fillcolor="#94DDF4",
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			label=drop_low_coverage,
			pos="974,188",
			rects="918.5,178.5,1029.5,197.5",
			width=1.5417];
	}
	subgraph cluster_outputs {
		graph [_draw_="S 6 -dashed c 7 -#000000 C 7 -#eeeeee P 4 8 8 8 63 1391 63 1391 8 ",
			_ldraw_="F 10 11 -Times-Roman c 7 -#000000 T 62 15 0 92 16 -Workflow Outputs ",
			bb="8,8,1391,63",
			label="Workflow Outputs",
			labelloc=b,
			lheight=0.15,
			lp="62,17.5",
			lwidth=1.28,
			rank=same,
			style=dashed
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		cn_scatter_plot	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 16.5 35.5 16.5 54.5 107.5 54.5 107.5 35.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 62 42.5 0 75 15 -cn_scatter_plot ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=cn_scatter_plot,
			pos="62,45",
			rects="16.5,35.5,107.5,54.5",
			width=1.2639];
		intervals_target	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 112 35.5 112 54.5 206 54.5 206 35.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 159 42.5 0 78 16 -intervals_target ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=intervals_target,
			pos="159,45",
			rects="112,35.5,206,54.5",
			width=1.3056];
		tumor_target_coverage	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 210.5 35.5 210.5 54.5 341.5 54.5 341.5 35.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 276 42.5 0 115 21 -tumor_target_coverage ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=tumor_target_coverage,
			pos="276,45",
			rects="210.5,35.5,341.5,54.5",
			width=1.8194];
		tumor_antitarget_coverage	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 345.5 35.5 345.5 54.5 494.5 54.5 494.5 35.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 420 42.5 0 133 25 -tumor_antitarget_coverage ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=tumor_antitarget_coverage,
			pos="420,45",
			rects="345.5,35.5,494.5,54.5",
			width=2.0694];
		normal_target_coverage	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 499 35.5 499 54.5 635 54.5 635 35.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 567 42.5 0 120 22 -normal_target_coverage ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=normal_target_coverage,
			pos="567,45",
			rects="499,35.5,635,54.5",
			width=1.8889];
		tumor_bin_level_ratios	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 639 35.5 639 54.5 767 54.5 767 35.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 703 42.5 0 112 22 -tumor_bin_level_ratios ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=tumor_bin_level_ratios,
			pos="703,45",
			rects="639,35.5,767,54.5",
			width=1.7778];
		tumor_segmented_ratios	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 771.5 35.5 771.5 54.5 910.5 54.5 910.5 35.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 841 42.5 0 123 22 -tumor_segmented_ratios ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=tumor_segmented_ratios,
			pos="841,45",
			rects="771.5,35.5,910.5,54.5",
			width=1.9306];
		cn_diagram	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 915 35.5 915 54.5 989 54.5 989 35.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 952 42.5 0 58 10 -cn_diagram ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=cn_diagram,
			pos="952,45",
			rects="915,35.5,989,54.5",
			width=1.0278];
		normal_antitarget_coverage	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 993.5 35.5 993.5 54.5 1148.5 54.5 1148.5 35.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1071 42.5 0 139 26 -normal_antitarget_coverage ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=normal_antitarget_coverage,
			pos="1071,45",
			rects="993.5,35.5,1148.5,54.5",
			width=2.1528];
		reference_coverage	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 1152.5 35.5 1152.5 54.5 1265.5 54.5 1265.5 35.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1209 42.5 0 97 18 -reference_coverage ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=reference_coverage,
			pos="1209,45",
			rects="1152.5,35.5,1265.5,54.5",
			width=1.5694];
		intervals_antitarget	[_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 1269.5 35.5 1269.5 54.5 1382.5 54.5 1382.5 35.5 ",
			_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 1326 42.5 0 97 20 -intervals_antitarget ",
			fillcolor="#94DDF4",
			height=0.27778,
			label=intervals_antitarget,
			pos="1326,45",
			rects="1269.5,35.5,1382.5,54.5",
			width=1.5694];
	}
	tumor_cram_to_bam	[_draw_="c 7 -#000000 C 7 -#fafad2 P 4 295.5 125.5 295.5 144.5 448.5 144.5 448.5 125.5 ",
		_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 372 132.5 0 137 25 -samtools view cram to bam ",
		height=0.27778,
		label="samtools view cram to bam",
		pos="372,135",
		rects="295.5,125.5,448.5,144.5",
		width=2.125];
	reference -> tumor_cram_to_bam	[_draw_="c 7 -#000000 B 10 441.81 178.64 433.28 173.88 422.47 167.73 413 162 406.67 158.17 405.24 156.97 399 153 396.94 151.69 394.79 150.33 \
392.64 148.97 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 393.98 146.92 386.75 145.26 391.37 151.06 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 433 155.6 0 40 9 -reference ",
		label=reference,
		lp="433,157.5",
		pos="e,385.47,144.45 441.81,178.64 433.28,173.88 422.47,167.73 413,162 406.67,158.17 405.24,156.97 399,153 396.94,151.69 394.79,150.33 \
392.64,148.97"];
	normal_cram_to_bam	[_draw_="c 7 -#000000 C 7 -#fafad2 P 4 501.5 125.5 501.5 144.5 654.5 144.5 654.5 125.5 ",
		_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 578 132.5 0 137 25 -samtools view cram to bam ",
		height=0.27778,
		label="samtools view cram to bam",
		pos="578,135",
		rects="501.5,125.5,654.5,144.5",
		width=2.125];
	reference -> normal_cram_to_bam	[_draw_="c 7 -#000000 B 7 468.71 178.68 479.89 171.08 497.43 159.98 514 153 519.46 150.7 525.32 148.63 531.19 146.81 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 531.7 149.21 537.73 144.88 530.32 144.51 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 534 155.6 0 40 9 -reference ",
		label=reference,
		lp="534,157.5",
		pos="e,539.18,144.46 468.71,178.68 479.89,171.08 497.43,159.98 514,153 519.46,150.7 525.32,148.63 531.19,146.81"];
	run_cnvkit	[_draw_="c 7 -#000000 C 7 -#fafad2 P 4 669 80.5 669 99.5 737 99.5 737 80.5 ",
		_ldraw_="F 10 9 -Helvetica c 7 -#000000 T 703 87.5 0 52 10 -run_cnvkit ",
		height=0.27778,
		label=run_cnvkit,
		pos="703,90",
		rects="669,80.5,737,99.5",
		width=0.94444];
	reference -> run_cnvkit	[_draw_="c 7 -#000000 B 7 454.41 178.52 450.93 165.27 446.63 139.64 460 125 486.2 96.31 598.45 91.24 660.81 90.7 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 660.76 93.15 667.75 90.66 660.74 88.25 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 480 133.1 0 40 9 -reference ",
		label=reference,
		lp="480,135",
		pos="e,669.26,90.653 454.41,178.52 450.93,165.27 446.63,139.64 460,125 486.2,96.309 598.45,91.243 660.81,90.701"];
	method -> run_cnvkit	[_draw_="c 7 -#000000 B 10 618.65 178.56 629.83 171.01 645.34 158.99 655 145 660.35 137.25 656.62 132.73 662 125 667.58 116.98 675.53 109.79 \
682.96 104.11 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 684.09 106.31 688.32 100.22 681.21 102.35 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 678 133.1 0 32 6 -method ",
		label=method,
		lp="678,135",
		pos="e,689.54,99.334 618.65,178.56 629.83,171.01 645.34,158.99 655,145 660.35,137.25 656.62,132.73 662,125 667.58,116.98 675.53,109.79 \
682.96,104.11"];
	tumor_cram -> tumor_cram_to_bam	[_draw_="c 7 -#000000 B 4 381.18 178.58 379.66 171.52 377.44 161.24 375.57 152.55 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 377.97 152.07 374.1 145.74 373.18 153.1 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 387.5 155.6 0 21 4 -cram ",
		label=cram,
		lp="387.5,157.5",
		pos="e,373.78,144.26 381.18,178.58 379.66,171.52 377.44,161.24 375.57,152.55"];
	bait_intervals -> run_cnvkit	[_draw_="c 7 -#000000 B 7 682.13 178.52 686.02 170.18 691.73 156.99 695 145 698.35 132.69 700.39 118.4 701.57 107.61 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 704 107.89 702.25 100.68 699.13 107.41 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 726.5 133.1 0 55 14 -bait_intervals ",
		label=bait_intervals,
		lp="726.5,135",
		pos="e,702.4,99.174 682.13,178.52 686.02,170.18 691.73,156.99 695,145 698.35,132.69 700.39,118.4 701.57,107.61"];
	access -> run_cnvkit	[_draw_="c 7 -#000000 B 7 752.56 178.79 757.38 166.34 764.36 142.31 755 125 750.03 115.81 741.37 108.71 732.53 103.43 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 733.79 101.32 726.47 100.14 731.46 105.63 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 773.5 133.1 0 29 6 -access ",
		label=access,
		lp="773.5,135",
		pos="e,725.14,99.413 752.56,178.79 757.38,166.34 764.36,142.31 755,125 750.03,115.81 741.37,108.71 732.53,103.43"];
	normal_cram -> normal_cram_to_bam	[_draw_="c 7 -#000000 B 4 540.43 178.58 547.18 170.93 557.28 159.48 565.31 150.39 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 566.91 152.27 569.71 145.4 563.24 149.03 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 572.5 155.6 0 21 4 -cram ",
		label=cram,
		lp="572.5,157.5",
		pos="e,570.71,144.26 540.43,178.58 547.18,170.93 557.28,159.48 565.31,150.39"];
	diagram -> run_cnvkit	[_draw_="c 7 -#000000 B 7 806.79 178.69 806.04 165.67 802.76 140.37 789 125 777.6 112.27 760.81 104.24 745.09 99.22 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 745.86 96.89 738.45 97.28 744.48 101.59 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 817 133.1 0 34 7 -diagram ",
		label=diagram,
		lp="817,135",
		pos="e,737,96.851 806.79,178.69 806.04,165.67 802.76,140.37 789,125 777.6,112.27 760.81,104.24 745.09,99.216"];
	scatter_plot -> run_cnvkit	[_draw_="c 7 -#000000 B 7 873.68 178.82 867.86 165.52 854.54 139.25 835 125 808.84 105.91 772.93 97.52 745.17 93.84 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 745.58 91.42 738.34 93.02 744.99 96.28 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 877.5 133.1 0 49 12 -scatter_plot ",
		label=scatter_plot,
		lp="877.5,135",
		pos="e,736.83,92.839 873.68,178.82 867.86,165.52 854.54,139.25 835,125 808.84,105.91 772.93,97.518 745.17,93.837"];
	drop_low_coverage -> run_cnvkit	[_draw_="c 7 -#000000 B 7 967.11 178.63 955.43 165.05 930.34 138.39 903 125 852.55 100.29 787.32 93.17 745.32 91.32 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 745.58 88.88 738.49 91.06 745.39 93.77 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 971.5 133.1 0 79 17 -drop_low_coverage ",
		label=drop_low_coverage,
		lp="971.5,135",
		pos="e,736.98,91.006 967.11,178.63 955.43,165.05 930.34,138.39 903,125 852.55,100.29 787.32,93.173 745.32,91.318"];
	tumor_cram_to_bam -> run_cnvkit	[_draw_="c 7 -#000000 B 7 380.35 125.56 386.96 119.48 396.75 111.72 407 108 452.45 91.51 590.6 90.06 660.91 90.47 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 660.61 92.91 667.63 90.51 660.65 88.01 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 430 110.6 0 46 9 -tumor_bam ",
		label=tumor_bam,
		lp="430,112.5",
		pos="e,669.14,90.524 380.35,125.56 386.96,119.48 396.75,111.72 407,108 452.45,91.505 590.6,90.065 660.91,90.466"];
	normal_cram_to_bam -> run_cnvkit	[_draw_="c 7 -#000000 B 7 585.3 125.63 590.9 119.76 599.17 112.22 608 108 624.37 100.18 643.89 95.93 660.96 93.64 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 660.96 96.11 667.62 92.84 660.38 91.24 ",
		_ldraw_="F 8 9 -Helvetica c 7 -#000000 T 633.5 110.6 0 51 10 -normal_bam ",
		label=normal_bam,
		lp="633.5,112.5",
		pos="e,669.12,92.66 585.3,125.63 590.9,119.76 599.17,112.22 608,108 624.37,100.18 643.89,95.935 660.96,93.638"];
	run_cnvkit -> cn_scatter_plot	[_draw_="c 7 -#000000 B 10 669.19 87.8 597.34 85.22 424.15 78.82 279 72 204.75 68.51 184.98 77.1 112 63 104.88 61.63 97.39 59.48 90.44 57.17 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 91.42 54.92 84 54.92 89.8 59.54 ",
		pos="e,82.576,54.415 669.19,87.803 597.34,85.223 424.15,78.821 279,72 204.75,68.511 184.98,77.095 112,63 104.88,61.625 97.392,59.478 \
90.439,57.167"];
	run_cnvkit -> intervals_target	[_draw_="c 7 -#000000 B 7 669.19 88.4 572.87 86.5 298.32 79.73 210 63 202.75 61.63 195.11 59.48 188.02 57.17 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 188.85 54.86 181.43 54.91 187.26 59.5 ",
		pos="e,180,54.417 669.19,88.399 572.87,86.499 298.32,79.731 210,63 202.75,61.627 195.11,59.48 188.02,57.169"];
	run_cnvkit -> tumor_target_coverage	[_draw_="c 7 -#000000 B 7 669.07 88.4 605.38 86.85 463.72 81.45 346 63 335.57 61.36 324.4 58.96 314.12 56.47 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 314.95 54.15 307.57 54.83 313.77 58.91 ",
		pos="e,306.1,54.467 669.07,88.396 605.38,86.849 463.72,81.452 346,63 335.57,61.365 324.4,58.959 314.12,56.469"];
	run_cnvkit -> tumor_antitarget_coverage	[_draw_="c 7 -#000000 B 7 669.3 85.59 628.74 81.29 558.65 73.2 499 63 487.65 61.06 475.46 58.62 464.13 56.19 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 464.9 53.85 457.54 54.76 463.86 58.64 ",
		pos="e,456.06,54.436 669.3,85.594 628.74,81.291 558.65,73.2 499,63 487.65,61.059 475.46,58.615 464.13,56.19"];
	run_cnvkit -> normal_target_coverage	[_draw_="c 7 -#000000 B 4 676.13 80.5 654.8 73.76 624.83 64.28 601.69 56.97 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 602.67 54.71 595.26 54.93 601.19 59.38 ",
		pos="e,593.81,54.478 676.13,80.505 654.8,73.761 624.83,64.284 601.69,56.967"];
	run_cnvkit -> tumor_bin_level_ratios	[_draw_="c 7 -#000000 B 4 703 80.71 703 75.59 703 68.85 703 62.67 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 705.45 62.78 703 55.78 700.55 62.78 ",
		pos="e,703,54.265 703,80.709 703,75.593 703,68.848 703,62.666"];
	run_cnvkit -> tumor_segmented_ratios	[_draw_="c 7 -#000000 B 4 730.26 80.5 751.91 73.76 782.32 64.28 805.8 56.97 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 806.39 59.35 812.35 54.93 804.94 54.67 ",
		pos="e,813.79,54.478 730.26,80.505 751.91,73.761 782.32,64.284 805.8,56.967"];
	run_cnvkit -> cn_diagram	[_draw_="c 7 -#000000 B 7 736.67 87.57 778.24 85.17 850.84 78.92 911 63 916.28 61.6 921.78 59.68 926.97 57.62 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 927.89 59.89 933.41 54.93 926 55.37 ",
		pos="e,934.8,54.341 736.67,87.57 778.24,85.173 850.84,78.92 911,63 916.28,61.603 921.78,59.676 926.97,57.62"];
	run_cnvkit -> normal_antitarget_coverage	[_draw_="c 7 -#000000 B 7 736.73 87.22 790.52 84.1 898.96 76.63 990 63 1002.12 61.18 1015.16 58.69 1027.16 56.17 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1027.46 58.61 1033.8 54.75 1026.44 53.82 ",
		pos="e,1035.3,54.435 736.73,87.221 790.52,84.099 898.96,76.63 990,63 1002.1,61.185 1015.2,58.692 1027.2,56.174"];
	run_cnvkit -> reference_coverage	[_draw_="c 7 -#000000 B 7 736.85 89.53 811.72 90.15 996.8 88.68 1149 63 1157.82 61.51 1167.19 59.21 1175.85 56.78 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1176.4 59.18 1182.43 54.86 1175.02 54.47 ",
		pos="e,1183.9,54.436 736.85,89.527 811.72,90.147 996.8,88.681 1149,63 1157.8,61.512 1167.2,59.214 1175.8,56.784"];
	run_cnvkit -> intervals_antitarget	[_draw_="c 7 -#000000 B 7 736.99 88.48 842.46 86.69 1163.31 79.98 1266 63 1274.82 61.54 1284.2 59.25 1292.85 56.82 ",
		_hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 1293.4 59.22 1299.43 54.9 1292.03 54.51 ",
		pos="e,1300.9,54.474 736.99,88.479 842.46,86.695 1163.3,79.982 1266,63 1274.8,61.541 1284.2,59.254 1292.9,56.824"];
}